Pip5k1c (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma) - Rat Genome Database

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Gene: Pip5k1c (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma) Rattus norvegicus
Analyze
Symbol: Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
RGD ID: 1309938
Description: Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and talin binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process; regulation of postsynaptic neurotransmitter receptor internalization; and regulation of synaptic vesicle endocytosis. Predicted to act upstream of or within axonogenesis; phosphatidylinositol biosynthetic process; and platelet aggregation. Is active in presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; E-cadherin signaling pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC314641; MGC124518; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; PIP5K1-gamma; PIP5KIgamma; ptdIns(4)P-5-kinase 1 gamma; ptdIns(4)P-5-kinase gamma; ptdInsPKIgamma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,048,135 - 9,076,751 (-)NCBIGRCr8
mRatBN7.278,397,406 - 8,426,030 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,397,406 - 8,425,988 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,282,985 - 11,310,700 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,158,469 - 13,186,184 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,026,097 - 11,053,748 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,267,207 - 11,294,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,267,218 - 11,294,249 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,433,945 - 11,461,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,881,767 - 9,909,651 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,884,380 - 9,909,590 (-)NCBI
Celera76,586,357 - 6,614,359 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
10. PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse. Wenk MR, etal., Neuron. 2001 Oct 11;32(1):79-88.
Additional References at PubMed
PMID:9535851   PMID:12477932   PMID:12847086   PMID:14741049   PMID:15386003   PMID:15481814   PMID:20622009   PMID:22243752   PMID:23372168   PMID:25588945   PMID:30053369  


Genomics

Comparative Map Data
Pip5k1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,048,135 - 9,076,751 (-)NCBIGRCr8
mRatBN7.278,397,406 - 8,426,030 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,397,406 - 8,425,988 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,282,985 - 11,310,700 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,158,469 - 13,186,184 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,026,097 - 11,053,748 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,267,207 - 11,294,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,267,218 - 11,294,249 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,433,945 - 11,461,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,881,767 - 9,909,651 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,884,380 - 9,909,590 (-)NCBI
Celera76,586,357 - 6,614,359 (-)NCBICelera
Cytogenetic Map7q11NCBI
PIP5K1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,630,183 - 3,700,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,630,183 - 3,700,468 (-)EnsemblGRCh38hg38GRCh38
GRCh37193,630,181 - 3,700,466 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,581,182 - 3,651,445 (-)NCBINCBI36Build 36hg18NCBI36
Build 34193,581,181 - 3,651,445NCBI
Celera193,567,024 - 3,637,289 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,395,505 - 3,464,912 (-)NCBIHuRef
CHM1_1193,629,775 - 3,700,077 (-)NCBICHM1_1
T2T-CHM13v2.0193,608,310 - 3,678,870 (-)NCBIT2T-CHM13v2.0
Pip5k1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,128,669 - 81,155,808 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,128,797 - 81,155,807 (+)EnsemblGRCm39 Ensembl
GRCm381081,292,835 - 81,319,974 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,292,963 - 81,319,973 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,755,717 - 80,782,719 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,696,109 - 80,721,034 (+)NCBIMGSCv36mm8
Celera1082,313,321 - 82,340,709 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Pip5k1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,573,549 - 5,617,847 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,573,549 - 5,616,957 (-)NCBIChiLan1.0ChiLan1.0
PIP5K1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,027,215 - 8,099,311 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,258,946 - 7,330,918 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,655,674 - 2,727,454 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,606,279 - 3,641,933 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,606,279 - 3,641,933 (-)Ensemblpanpan1.1panPan2
PIP5K1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,751,055 - 55,801,740 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,751,158 - 55,799,160 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,476,548 - 55,527,110 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,411,292 - 56,461,900 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,411,262 - 56,459,374 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,467,880 - 55,517,545 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,950,522 - 56,001,018 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,149,116 - 56,199,654 (+)NCBIUU_Cfam_GSD_1.0
Pip5k1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,746,672 - 215,763,912 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,068,952 - 2,091,956 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,070,873 - 2,088,144 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP5K1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,977,274 - 75,046,895 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,977,266 - 75,046,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,568,768 - 75,615,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIP5K1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,389,575 - 3,454,108 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,389,056 - 3,453,836 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,797,989 - 5,073,344 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip5k1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248286,324,156 - 6,369,394 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pip5k1c
99 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:691
Count of miRNA genes:283
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000061159
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat

Markers in Region
RH139092  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,398,409 - 8,398,594 (+)MAPPERmRatBN7.2
Rnor_6.0711,268,211 - 11,268,395NCBIRnor6.0
Rnor_5.0711,434,949 - 11,435,133UniSTSRnor5.0
RGSC_v3.479,882,771 - 9,882,955UniSTSRGSC3.4
Celera76,587,361 - 6,587,545UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 35 22 6 19 6 3 74 34 33 11
Low 1 8 35 35 35 8 8 1 8 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC094643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY850259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB557931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB581409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB696331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK366332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000061159   ⟹   ENSRNOP00000057873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,397,417 - 8,425,988 (-)Ensembl
Rnor_6.0 Ensembl711,267,218 - 11,294,249 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088364   ⟹   ENSRNOP00000068990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,397,406 - 8,425,988 (-)Ensembl
Rnor_6.0 Ensembl711,267,218 - 11,294,249 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095691   ⟹   ENSRNOP00000086276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,397,417 - 8,413,392 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107025   ⟹   ENSRNOP00000077990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,401,782 - 8,425,988 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115219   ⟹   ENSRNOP00000097462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,397,417 - 8,413,392 (-)Ensembl
RefSeq Acc Id: NM_001009967   ⟹   NP_001009967
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,135 - 9,076,716 (-)NCBI
mRatBN7.278,397,406 - 8,425,988 (-)NCBI
Rnor_6.0711,267,207 - 11,294,249 (-)NCBI
Rnor_5.0711,433,945 - 11,461,690 (-)NCBI
RGSC_v3.479,881,767 - 9,909,651 (-)RGD
Celera76,586,357 - 6,614,359 (-)RGD
Sequence:
RefSeq Acc Id: NM_001033970   ⟹   NP_001029142
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,135 - 9,076,716 (-)NCBI
mRatBN7.278,397,406 - 8,425,988 (-)NCBI
Rnor_6.0711,267,207 - 11,294,249 (-)NCBI
Rnor_5.0711,433,945 - 11,461,690 (-)NCBI
RGSC_v3.479,881,767 - 9,909,651 (-)RGD
Celera76,586,357 - 6,614,359 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240935   ⟹   XP_006240997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,137 - 9,076,747 (-)NCBI
mRatBN7.278,397,406 - 8,426,028 (-)NCBI
Rnor_6.0711,267,207 - 11,294,290 (-)NCBI
Rnor_5.0711,433,945 - 11,461,690 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765101   ⟹   XP_008763323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,137 - 9,076,748 (-)NCBI
mRatBN7.278,397,406 - 8,426,029 (-)NCBI
Rnor_6.0711,267,207 - 11,294,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765103   ⟹   XP_008763325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,137 - 9,076,751 (-)NCBI
mRatBN7.278,397,406 - 8,426,028 (-)NCBI
Rnor_6.0711,267,207 - 11,294,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079020   ⟹   XP_038934948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,048,137 - 9,076,748 (-)NCBI
mRatBN7.278,397,406 - 8,426,030 (-)NCBI
RefSeq Acc Id: NP_001009967   ⟸   NM_001009967
- Peptide Label: isoform c
- UniProtKB: F1M8H6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001029142   ⟸   NM_001033970
- Peptide Label: isoform b
- UniProtKB: Q3MID5 (UniProtKB/TrEMBL),   A0A8I5XWP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240997   ⟸   XM_006240935
- Peptide Label: isoform X4
- UniProtKB: F1M8H6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763325   ⟸   XM_008765103
- Peptide Label: isoform X3
- UniProtKB: F1M8H6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763323   ⟸   XM_008765101
- Peptide Label: isoform X1
- UniProtKB: F1M8H6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057873   ⟸   ENSRNOT00000061159
RefSeq Acc Id: ENSRNOP00000068990   ⟸   ENSRNOT00000088364
RefSeq Acc Id: XP_038934948   ⟸   XM_039079020
- Peptide Label: isoform X2
- UniProtKB: F1M8H6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000097462   ⟸   ENSRNOT00000115219
RefSeq Acc Id: ENSRNOP00000086276   ⟸   ENSRNOT00000095691
RefSeq Acc Id: ENSRNOP00000077990   ⟸   ENSRNOT00000107025
Protein Domains
PIPK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5I6B8-F1-model_v2 AlphaFold Q5I6B8 1-688 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694977
Promoter ID:EPDNEW_R5502
Type:multiple initiation site
Name:Pip5k1c_1
Description:phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,294,270 - 11,294,330EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309938 AgrOrtholog
BioCyc Gene G2FUF-35013 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6352 [3-phosphoinositide biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6352 BioCyc
Ensembl Genes ENSRNOG00000020577 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061159 ENTREZGENE
  ENSRNOT00000061159.5 UniProtKB/TrEMBL
  ENSRNOT00000088364.2 UniProtKB/TrEMBL
  ENSRNOT00000095691 ENTREZGENE
  ENSRNOT00000095691.1 UniProtKB/TrEMBL
  ENSRNOT00000107025.1 UniProtKB/TrEMBL
  ENSRNOT00000115219.1 UniProtKB/TrEMBL
Gene3D-CATH 2-Layer Sandwich UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.800.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7933923 IMAGE-MGC_LOAD
InterPro PInositol-4-P-5-kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314641 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:124518 IMAGE-MGC_LOAD
NCBI Gene 314641 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23086 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PIP5K UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pip5k1c PhenoGen
PROSITE PIPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020577 RatGTEx
SMART PIPKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JU72_RAT UniProtKB/TrEMBL
  A0A8I5XWP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3A3_RAT UniProtKB/TrEMBL
  A0A8I6ARF9_RAT UniProtKB/TrEMBL
  F1M8H6 ENTREZGENE, UniProtKB/TrEMBL
  PI51C_RAT UniProtKB/Swiss-Prot
  Q3MID5 ENTREZGENE, UniProtKB/TrEMBL
  Q5I6B8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-20 Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase type 1 gamma  Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma  Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma  Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pip5k1c  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma  Pip5k1c_predicted  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pip5k1c_predicted  phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (predicted)      Symbol and Name status set to approved 70820 APPROVED