Gene: Mrap2 (melanocortin 2 receptor accessory protein 2) Rattus norvegicus
Analyze
Symbol:
Mrap2
Name:
melanocortin 2 receptor accessory protein 2
RGD ID:
1309873
Description:
Predicted to enable identical protein binding activity; melanocortin receptor binding activity; and signaling receptor regulator activity. Predicted to be involved in several processes, including negative regulation of protein localization to plasma membrane; protein localization to plasma membrane; and regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
hypothetical protein LOC363112; LOC363112; melanocortin-2 receptor accessory protein 2; RGD1309873; similar to hypothetical protein BC010003; uncharacterized protein LOC363112
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 96,968,239 - 97,024,581 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 8 96,988,079 - 97,024,579 (+) Ensembl GRCr8 mRatBN7.2 8 88,088,293 - 88,144,636 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 88,088,272 - 88,143,886 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 8 93,759,921 - 93,815,629 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 91,959,128 - 92,014,842 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 89,792,874 - 89,848,464 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 8 97,882,191 - 97,937,776 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 8 99,978,244 - 100,033,823 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 8 98,467,514 - 98,523,097 (+) NCBI Lyon_Hypertensive F344_StmMcwi 8 89,923,827 - 89,979,854 (+) NCBI F344_StmMcwi Rnor_6.0 8 94,801,336 - 94,858,192 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 94,801,336 - 94,857,443 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 8 94,308,773 - 94,370,052 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 8 92,385,844 - 92,442,482 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 8 87,674,071 - 87,729,420 (+) NCBI Celera RGSC_v3.1 8 92,405,298 - 92,462,270 (+) NCBI Cytogenetic Map 8 q31 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Mrap2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Mrap2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mrap2 Rat 1,2-dichloroethane increases expression ISO Mrap2 (Mus musculus) 6480464 ethylene dichloride results in increased expression of MRAP2 mRNA CTD PMID:28960355 Mrap2 Rat 17beta-estradiol multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of MRAP2 mRNA; [Estradiol co-treated more ... CTD PMID:20404318|PMID:30165855 Mrap2 Rat 17beta-estradiol decreases expression ISO Mrap2 (Mus musculus) 6480464 Estradiol results in decreased expression of MRAP2 mRNA CTD PMID:39298647 Mrap2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Mrap2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mrap2 Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Mrap2 (Mus musculus) 6480464 2,2',4,4'-tetrabromodiphenyl ether affects the expression of MRAP2 mRNA CTD PMID:30294300 Mrap2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Mrap2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mrap2 Rat 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO MRAP2 (Homo sapiens) 6480464 2,5,2',5'-tetrachlorobiphenyl analog results in decreased expression of MRAP2 mRNA CTD PMID:36804509 Mrap2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Mrap2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mrap2 Rat 4,4'-sulfonyldiphenol increases expression ISO Mrap2 (Mus musculus) 6480464 bisphenol S results in increased expression of MRAP2 mRNA CTD PMID:39298647 Mrap2 Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Mrap2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MRAP2 mRNA CTD PMID:24780913 Mrap2 Rat Aflatoxin B2 alpha increases methylation ISO MRAP2 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of MRAP2 intron CTD PMID:30157460 Mrap2 Rat all-trans-retinoic acid decreases expression ISO MRAP2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of MRAP2 mRNA CTD PMID:23724009 Mrap2 Rat all-trans-retinoic acid multiple interactions ISO Mrap2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MRAP2 mRNA CTD PMID:36189433 Mrap2 Rat all-trans-retinoic acid decreases expression ISO Mrap2 (Mus musculus) 6480464 Tretinoin results in decreased expression of MRAP2 mRNA CTD PMID:36189433 Mrap2 Rat arsane multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MRAP2 more ... CTD PMID:32525701 Mrap2 Rat arsenic atom multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MRAP2 more ... CTD PMID:32525701 Mrap2 Rat arsenous acid decreases expression ISO MRAP2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MRAP2 mRNA CTD PMID:26705709 Mrap2 Rat atrazine increases expression ISO MRAP2 (Homo sapiens) 6480464 Atrazine results in increased expression of MRAP2 mRNA CTD PMID:22378314 Mrap2 Rat benzo[a]pyrene affects methylation ISO MRAP2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MRAP2 promoter CTD PMID:27901495 Mrap2 Rat benzo[e]pyrene increases methylation ISO MRAP2 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of MRAP2 intron CTD PMID:30157460 Mrap2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MRAP2 mRNA CTD PMID:25181051|PMID:34947998|PMID:41034487 Mrap2 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Mrap2 Rat bisphenol A decreases methylation ISO MRAP2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of MRAP2 gene CTD PMID:31601247 Mrap2 Rat bisphenol A multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MRAP2 gene CTD PMID:31601247 Mrap2 Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 Mrap2 Rat cadmium atom multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MRAP2 more ... CTD PMID:35301059 Mrap2 Rat cadmium dichloride multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MRAP2 more ... CTD PMID:35301059 Mrap2 Rat carbamazepine affects expression ISO MRAP2 (Homo sapiens) 6480464 Carbamazepine affects the expression of MRAP2 mRNA CTD PMID:25979313 Mrap2 Rat carbon nanotube increases expression ISO Mrap2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of MRAP2 mRNA CTD PMID:25620056 Mrap2 Rat copper(II) sulfate decreases expression ISO MRAP2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of MRAP2 mRNA CTD PMID:19549813 Mrap2 Rat deoxynivalenol decreases expression ISO MRAP2 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of MRAP2 mRNA CTD PMID:31863870 Mrap2 Rat diarsenic trioxide decreases expression ISO MRAP2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MRAP2 mRNA CTD PMID:26705709 Mrap2 Rat diazinon increases methylation ISO MRAP2 (Homo sapiens) 6480464 Diazinon results in increased methylation of MRAP2 gene CTD PMID:22964155 Mrap2 Rat ethanol affects expression ISO Mrap2 (Mus musculus) 6480464 Ethanol affects the expression of MRAP2 mRNA CTD PMID:30319688 Mrap2 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of MRAP2 mRNA CTD PMID:30307764 Mrap2 Rat fulvestrant multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MRAP2 gene CTD PMID:31601247 Mrap2 Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of MRAP2 mRNA CTD PMID:36653537 Mrap2 Rat methapyrilene increases methylation ISO MRAP2 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of MRAP2 intron CTD PMID:30157460 Mrap2 Rat methylmercury chloride decreases expression ISO MRAP2 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of MRAP2 mRNA CTD PMID:28001369 Mrap2 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Mrap2 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MRAP2 mRNA CTD PMID:36189433 Mrap2 Rat nickel atom decreases expression ISO MRAP2 (Homo sapiens) 6480464 Nickel results in decreased expression of MRAP2 mRNA CTD PMID:24768652|PMID:25583101 Mrap2 Rat okadaic acid decreases expression ISO MRAP2 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of MRAP2 mRNA CTD PMID:38832940 Mrap2 Rat PCB138 multiple interactions ISO Mrap2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Mrap2 Rat resveratrol multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of MRAP2 mRNA CTD PMID:23557933 Mrap2 Rat silicon dioxide decreases expression ISO MRAP2 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of MRAP2 mRNA CTD PMID:25895662 Mrap2 Rat sodium arsenate multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MRAP2 more ... CTD PMID:32525701 Mrap2 Rat sotorasib multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MRAP2 mRNA CTD PMID:36139627 Mrap2 Rat T-2 toxin decreases expression ISO MRAP2 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of MRAP2 mRNA CTD PMID:31863870 Mrap2 Rat Theaflavin 3,3'-digallate affects expression ISO MRAP2 (Homo sapiens) 6480464 theaflavin-3,3'-digallate affects the expression of MRAP2 mRNA CTD PMID:34925699 Mrap2 Rat thimerosal decreases expression ISO MRAP2 (Homo sapiens) 6480464 Thimerosal results in decreased expression of MRAP2 mRNA CTD PMID:27188386 Mrap2 Rat titanium dioxide decreases expression ISO Mrap2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of MRAP2 mRNA CTD PMID:29264374 Mrap2 Rat trametinib multiple interactions ISO MRAP2 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MRAP2 mRNA CTD PMID:36139627 Mrap2 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of MRAP2 mRNA CTD PMID:33387578 Mrap2 Rat triclosan decreases expression ISO MRAP2 (Homo sapiens) 6480464 Triclosan results in decreased expression of MRAP2 mRNA CTD PMID:30510588 Mrap2 Rat tunicamycin decreases expression ISO MRAP2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of MRAP2 mRNA CTD PMID:22378314 Mrap2 Rat valproic acid increases expression ISO MRAP2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of MRAP2 mRNA CTD PMID:24935251