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Gene: Traip (TRAF-interacting protein) Rattus norvegicus

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Symbol:

Traip

Name:

TRAF-interacting protein

RGD ID:

1309761

Description:

Predicted to enable identical protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of interferon-beta production; negative regulation of tumor necrosis factor-mediated signaling pathway; and replication fork processing. Predicted to act upstream of or within signal transduction. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus and site of DNA damage. Human ortholog(s) of this gene implicated in Seckel syndrome 9. Orthologous to human TRAIP (TRAF interacting protein); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 1H-pyrazole.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

E3 ubiquitin-protein ligase TRAIP; LOC367167

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRAIP (TRAF interacting protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Traip (TRAF-interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Traip (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRAIP (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRAIP (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Traip (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRAIP (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRAIP (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Traip (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Traip (TRAF interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Traip (TRAF-interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TRAIP (TRAF interacting protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	traip (TRAF-interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	traip (TRAF-interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	B0432.13	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	B0432.13	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	nopo	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	nopo	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	traip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	traip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,520,476 - 117,540,253 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,520,441 - 117,540,253 (+)	Ensembl				GRCr8
mRatBN7.2	8	108,641,860 - 108,661,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,641,852 - 108,661,638 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,268,299 - 114,288,111 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,467,623 - 112,487,434 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,310,262 - 110,330,074 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,730,170 - 116,750,528 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,730,641 - 116,750,709 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,085,076 - 116,104,852 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,220,855 - 113,240,631 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	107,946,305 - 107,966,080 (+)	NCBI		Celera
RGSC_v3.1	8	113,240,295 - 113,260,085 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Desbuquois dysplasia (ISO)

Dwarfism (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

microcephaly (ISO)

Seckel syndrome 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

1H-pyrazole (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-palmitoylglycerol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

DDE (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

ethanol (EXP)

ethyl methanesulfonate (ISO)

folic acid (ISO)

furan (EXP)

gallic acid (ISO)

geraniol (ISO)

ketamine (EXP)

L-methionine (ISO)

lidocaine (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

p-menthan-3-ol (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (ISO)

trimellitic anhydride (ISO)

trovafloxacin (ISO)

tungsten (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA,ISO)

DNA repair (IEA)

negative regulation of interferon-beta production (IEA,ISO)

negative regulation of tumor necrosis factor-mediated signaling pathway (IEA,ISO)

obsolete negative regulation of NF-kappaB transcription factor activity (ISO)

protein ubiquitination (IBA,IEA,ISO)

replication fork processing (IBA,IEA,ISO)

signal transduction (IEA,ISO)

Cellular Component

chromosome (IEA)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IEA,ISO)

site of DNA damage (IBA,IEA,ISO)

Molecular Function

identical protein binding (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (IBA,IEA,ISO)

ubiquitin-protein transferase activity (IEA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9104814	PMID:9109628	PMID:12477932	PMID:17544371	PMID:19151749	PMID:22945920	PMID:27462463

Genomics

Comparative Map Data

Traip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,520,476 - 117,540,253 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,520,441 - 117,540,253 (+)	Ensembl				GRCr8
mRatBN7.2	8	108,641,860 - 108,661,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,641,852 - 108,661,638 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,268,299 - 114,288,111 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,467,623 - 112,487,434 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,310,262 - 110,330,074 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,730,170 - 116,750,528 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,730,641 - 116,750,709 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,085,076 - 116,104,852 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,220,855 - 113,240,631 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	107,946,305 - 107,966,080 (+)	NCBI		Celera
RGSC_v3.1	8	113,240,295 - 113,260,085 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

TRAIP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	49,828,601 - 49,856,564 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	49,828,595 - 49,856,597 (-)	Ensembl			hg38	GRCh38
GRCh37	3	49,866,034 - 49,893,997 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,841,032 - 49,868,996 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	3	49,831,372 - 49,859,800 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,924,552 - 49,952,533 (-)	NCBI		HuRef
CHM1_1	3	49,818,089 - 49,846,065 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	49,858,496 - 49,886,461 (-)	NCBI		T2T-CHM13v2.0

Traip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,828,158 - 107,849,469 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,827,335 - 107,849,469 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	107,950,325 - 107,972,270 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	107,950,136 - 107,972,270 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	107,853,294 - 107,874,599 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,809,064 - 107,830,369 (+)	NCBI		MGSCv36	mm8
Celera	9	107,559,385 - 107,580,687 (+)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	59.07	NCBI

Traip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,726,061 - 1,746,591 (-)	Ensembl
ChiLan1.0	NW_004955532	1,725,608 - 1,746,690 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRAIP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	49,813,521 - 49,844,114 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	49,818,276 - 49,848,889 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	49,760,528 - 49,789,637 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	50,996,647 - 51,025,243 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	50,996,647 - 51,025,241 (-)	Ensembl			panPan2	panpan1.1

TRAIP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,430,109 - 39,454,437 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,430,489 - 39,453,933 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	39,351,169 - 39,375,285 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,787,196 - 39,811,318 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,787,356 - 39,811,310 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	39,154,232 - 39,178,342 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,558,472 - 39,582,589 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	39,838,028 - 39,862,140 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Traip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	64,674,131 - 64,705,756 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	1,435,089 - 1,465,016 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	1,434,629 - 1,466,382 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRAIP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,345,599 - 32,379,766 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	32,332,336 - 32,380,988 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	35,523,737 - 35,561,789 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRAIP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	11,220,152 - 11,262,942 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	11,233,996 - 11,262,830 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	155,734,150 - 155,764,250 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Traip
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	3,748,894 - 3,774,489 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	3,749,183 - 3,775,062 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Traip
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	99,282,854 - 99,303,378 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Traip
228 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	276
Count of miRNA genes:	184
Interacting mature miRNAs:	210
Transcripts:	ENSRNOT00000052289
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

PMC126259P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,640,093 - 108,640,174 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,728,986 - 116,729,066	NCBI	Rnor6.0
Rnor_5.0	8	116,083,310 - 116,083,390	UniSTS	Rnor5.0
RGSC_v3.4	8	113,219,089 - 113,219,169	UniSTS	RGSC3.4
Celera	8	107,944,539 - 107,944,619	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH137038

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,661,428 - 108,661,612 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,750,317 - 116,750,500	NCBI	Rnor6.0
Rnor_5.0	8	116,104,641 - 116,104,824	UniSTS	Rnor5.0
RGSC_v3.4	8	113,240,420 - 113,240,603	UniSTS	RGSC3.4
Celera	8	107,965,869 - 107,966,052	UniSTS
RH 3.4 Map	8	1117.2	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	64	159	88	87	56	86	56	6	339	183	11	138	76	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC162006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000052289 ⟹ ENSRNOP00000048198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,520,441 - 117,540,253 (+)	Ensembl
mRatBN7.2 Ensembl	8	108,641,860 - 108,661,638 (+)	Ensembl
Rnor_6.0 Ensembl	8	116,730,641 - 116,750,709 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118550 ⟹ ENSRNOP00000096734

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,520,441 - 117,540,253 (+)	Ensembl
mRatBN7.2 Ensembl	8	108,641,852 - 108,661,633 (+)	Ensembl

RefSeq Acc Id:

NM_001109004 ⟹ NP_001102474

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,520,476 - 117,540,253 (+)	NCBI
mRatBN7.2	8	108,641,860 - 108,661,640 (+)	NCBI
Rnor_6.0	8	116,730,752 - 116,750,528 (+)	NCBI
Rnor_5.0	8	116,085,076 - 116,104,852 (+)	NCBI
RGSC_v3.4	8	113,220,855 - 113,240,631 (+)	RGD
Celera	8	107,946,305 - 107,966,080 (+)	RGD

Sequence:

show sequence

GTGGGAACCGCGGCCGGTTCGGCCACCCAACTGTGTCTGTTGCTGGCTGCTGGCTCTCTGTGCT
GCTTGAGCCGAGCCATCATGCCTATCCGCGCGCTGTGCACTATCTGCTCCGATTTCTTCGATCA
CTCCCGTGACGTGGCTGCCATCCACTGTGGCCACACTTTTCATCTGCAATGCCTAATCCAGTGG
TTTGAGACAGCACCAAGTCGGACCTGCCCCCAGTGTAGAATCCAGGTTGGCAAAAAGACTATCA
TCAACAAGCTCTTTTTTGACCTTGCCCAGGAAGAGGAGAGTGTCTTGGATGCAGAATTCTTAAA
GAATGAACTGGACAGTATCAAGGCCCAGCTCTCCCAAAAAGACAGGGAGAAACGGGACAGCCAG
GCCATTATCGACACTCTACGGGACACATTGGAGGAACGCAATGCCACTGTGGAGTCCCTGCAGA
ACGCCTTAAACAAGGCAGAGATGCTGTGTTCCACCCTGAAAAAACAGATGAAATTCCTGGAGCA
GCAGCGGGATGAGACCAAACACGCTCAGGAGGAGGCCCGCCAACTCAAGAGCAAGATGAAAACC
ATGGAGCAAATTGAGCTCCTACTCCAGAGCCAGCGGTCTGAGGTAGAGGAGATGATCCGAGACA
TGGGTGTGGGACAGTCAGCGGTGGAGCAGCTAGCTGTGTACTGCATATCCCTCAAGAAAGAGTA
TGAGAATCTGAAAGAAGCTCGGAAGGCCTCAGGGGAGCTGGCTGACAGGCTGAGGAAAGACTTG
GCGTCTTCTAGGAGCAAGCTGAAGACTGTCAACACTGAGCTGGATCAGGCCAAGTTAGAACTGA
GGTCAGCCCAGAAGGACTTACAGAGCGCTGACAAGGAGATCACGAGCCTAAGAAAGAAGCTAAC
GATCCTGCAGGGGACCTTGAGCCTGCCTCCAGTGACCAGTGAGACTGTCAGCCGCCTGGTTTTT
GAGAGCCCAGCCCCCGTGGAAATGCTGAAGCCAAGGCTTCACCGACCACCCTTCAGTGATGAGA
TTGATCTCAACGCTACCTTTGATGTAAATACCCCTCCTGCCCAGACCTCCAGCTCCCAGCATTG
CCACCCCAAGAAGCTCTGCCTGGAGAGGGCACGCTCTCCCATGCAGGACATCCTCAAGATACCC
AAAGTCTCCAAGTCGGAGTCCCAGCTCTCACTGGGTGGCCAGCGATGTGTAGGAGAGCCAGATG
AGGAGCTGGCTGGTGCCTTCCCTCTCTTCATCCGGAATGCTGTCCGGGGTCAGAAACAGCCCAA
CAGGACCACAGCAGAATCCCGTTACAGCACAGATGTGGTAAGAATAGGCTTCGATGGGCTTGGA
GGACGAACAAAATTCATCCAACCTACAGACCCAACCATTATCCGACCAATGCCTGTTAAACCCA
AGGCCAAGAGTAAACAGAAAGTGAGAATAAAGACTGTGAATTCTGCCTCCCAGCCCAAGCTGGA
TACCTTCTTATGTCAGTGAAGTGACCAGAGTCATGTCTTCAATCAGTAGACCAAGACCTGGCCA
ACCGGAAGTGTTTTAGAAGATGGCTCCTCTTGGAACAGTCTAAGAAAGAGGCCCAGAAAACACA
CTTACTGTGTTCACTGCGCCCTGTACCACACTGGGAAGTGACGTGACCAGTTTACAGTTCTGAT
CAGCAGGGCCTGCTTCTAGTTGCAGGGTTTTGCTTATAGCTACAACTGGGAGTGGCTGGGCTCC
TTCTGGTTTTATAGAACAGGGTCACATTGACTCTTAAGTGGACGGAAGTGCTGGAGGATTCCTA
AGCAGGCCACCTTGAACTTCTGCCTGCCTCCAGTTTTATTGCTTGAAATGGGGGTTTTGGGGGG
ATGATAGGGAAGGTTTCCGTGTAAAATAAAAAGGCATCTTTTCTTCTAGAAAAAAAAAAAAAAA
AAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039081887 ⟹ XP_038937815

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,528,650 - 117,540,252 (+)	NCBI
mRatBN7.2	8	108,650,025 - 108,661,639 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102474	(Get FASTA)	NCBI Sequence Viewer
	XP_038937815	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI62006	(Get FASTA)	NCBI Sequence Viewer
	EDL77208	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000048198
	ENSRNOP00000048198.3
	ENSRNOP00000096734.2

RefSeq Acc Id:

NP_001102474 ⟸ NM_001109004

- UniProtKB:

B1WC52 (UniProtKB/TrEMBL), F7ETT8 (UniProtKB/TrEMBL), A0A8I6GLQ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFF
DLAQEEESVLDAEFLKNELDSIKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKA
EMLCSTLKKQMKFLEQQRDETKHAQEEARQLKSKMKTMEQIELLLQSQRSEVEEMIRDMGVGQS
AVEQLAVYCISLKKEYENLKEARKASGELADRLRKDLASSRSKLKTVNTELDQAKLELRSAQKD
LQSADKEITSLRKKLTILQGTLSLPPVTSETVSRLVFESPAPVEMLKPRLHRPPFSDEIDLNAT
FDVNTPPAQTSSSQHCHPKKLCLERARSPMQDILKIPKVSKSESQLSLGGQRCVGEPDEELAGA
FPLFIRNAVRGQKQPNRTTAESRYSTDVVRIGFDGLGGRTKFIQPTDPTIIRPMPVKPKAKSKQ
KVRIKTVNSASQPKLDTFLCQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000048198 ⟸ ENSRNOT00000052289

RefSeq Acc Id:	XP_038937815 ⟸ XM_039081887
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000096734 ⟸ ENSRNOT00000118550

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WC52-F1-model_v2	AlphaFold	B1WC52	1-469	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696284

Promoter ID:

EPDNEW_R6809

Type:

single initiation site

Name:

Traip_1

Description:

TRAF-interacting protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	116,730,723 - 116,730,783	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309761	AgrOrtholog
BioCyc Gene	G2FUF-29166	BioCyc
Ensembl Genes	ENSRNOG00000030101	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000052289	ENTREZGENE
	ENSRNOT00000052289.6	UniProtKB/TrEMBL
	ENSRNOT00000118550.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9089897	IMAGE-MGC_LOAD
InterPro	TRAIP_ubiq-protein_ligase	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
KEGG Report	rno:367167	UniProtKB/TrEMBL
MGC_CLONE	MGC:187865	IMAGE-MGC_LOAD
NCBI Gene	367167	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE TRAIP	UniProtKB/TrEMBL
Pfam	zf-RING_2	UniProtKB/TrEMBL
PhenoGen	Traip	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030101	RatGTEx
SMART	RING	UniProtKB/TrEMBL
Superfamily-SCOP	Prefoldin	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A8I6GLQ9	ENTREZGENE, UniProtKB/TrEMBL
	B1WC52	ENTREZGENE, UniProtKB/TrEMBL
	F7ETT8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Traip	TRAF-interacting protein	Traip_predicted	TRAF-interacting protein (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Traip_predicted	TRAF-interacting protein (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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