Cdk18 (cyclin-dependent kinase 18) - Rat Genome Database

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Gene: Cdk18 (cyclin-dependent kinase 18) Rattus norvegicus
Analyze
Symbol: Cdk18
Name: cyclin-dependent kinase 18
RGD ID: 1309523
Description: Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in positive regulation of myelination and regulation of cell cycle phase transition. Predicted to be active in cytoplasm and nucleus. Orthologous to human CDK18 (cyclin dependent kinase 18); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cell division protein kinase 18; LOC289019; PCTAIRE protein kinase 3; PCTAIRE-motif protein kinase 3; PCTAIRE3; Pctk3; serine/threonine-protein kinase PCTAIRE-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81346,107,763 - 46,140,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1346,108,911 - 46,140,865 (-)EnsemblGRCr8
mRatBN7.21343,555,597 - 43,582,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,556,748 - 43,588,525 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1346,164,010 - 46,172,223 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,452,154 - 47,460,367 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01344,712,855 - 44,721,069 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01348,893,525 - 48,926,673 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,893,412 - 48,927,483 (-)Ensemblrn6Rnor6.0
Rnor_5.01353,963,482 - 53,996,384 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,996,447 - 45,004,813 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1343,894,168 - 43,902,442 (-)NCBICelera
RGSC_v3.11345,010,140 - 45,052,495 (-)NCBI
Cytogenetic Map13q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (EXP)
amosite asbestos  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper(II) chloride  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
FR900359  (ISO)
inulin  (ISO)
lead diacetate  (ISO)
methoxyacetic acid  (EXP)
methylseleninic acid  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rotenone  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9370357   PMID:12477932   PMID:16641100   PMID:34800366  


Genomics

Comparative Map Data
Cdk18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81346,107,763 - 46,140,705 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1346,108,911 - 46,140,865 (-)EnsemblGRCr8
mRatBN7.21343,555,597 - 43,582,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,556,748 - 43,588,525 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1346,164,010 - 46,172,223 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,452,154 - 47,460,367 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01344,712,855 - 44,721,069 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01348,893,525 - 48,926,673 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,893,412 - 48,927,483 (-)Ensemblrn6Rnor6.0
Rnor_5.01353,963,482 - 53,996,384 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,996,447 - 45,004,813 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1343,894,168 - 43,902,442 (-)NCBICelera
RGSC_v3.11345,010,140 - 45,052,495 (-)NCBI
Cytogenetic Map13q13NCBI
CDK18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381205,504,669 - 205,532,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1205,504,561 - 205,532,976 (+)Ensemblhg38GRCh38
GRCh371205,473,797 - 205,501,918 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361203,740,350 - 203,768,541 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1178,608,860 - 178,637,096 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1176,639,088 - 176,667,323 (+)NCBIHuRef
CHM1_11206,896,957 - 206,925,197 (+)NCBICHM1_1
T2T-CHM13v2.01204,769,067 - 204,797,187 (+)NCBIT2T-CHM13v2.0
Cdk18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,041,285 - 132,067,433 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,039,975 - 132,067,422 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381132,113,547 - 132,139,698 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,112,237 - 132,139,684 (-)Ensemblmm10GRCm38
MGSCv371134,010,124 - 134,036,262 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361133,941,206 - 133,967,230 (-)NCBIMGSCv36mm8
Celera1134,717,874 - 134,746,292 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.24NCBI
Cdk18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540641,228,678 - 41,252,543 (+)Ensembl
ChiLan1.0NW_00495540641,228,802 - 41,256,413 (+)NCBIChiLan1.0ChiLan1.0
CDK18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2143,836,989 - 43,865,185 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1143,802,241 - 43,830,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01181,113,560 - 181,141,758 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11185,399,156 - 185,427,631 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1185,399,162 - 185,427,631 (+)EnsemblpanPan2panpan1.1
CDK18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1381,978,128 - 2,005,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl381,990,061 - 2,002,321 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha382,069,268 - 2,096,515 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0381,972,641 - 1,999,890 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl381,974,237 - 1,999,888 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1381,970,139 - 1,994,040 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0382,361,384 - 2,385,523 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0382,559,737 - 2,587,029 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdk18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934469,651,482 - 69,678,141 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365576,891,806 - 6,918,429 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365576,891,764 - 6,918,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl966,175,678 - 66,202,795 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1966,175,539 - 66,202,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2972,427,470 - 72,448,210 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12523,809,633 - 23,838,350 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2523,809,352 - 23,838,345 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605524,508,636 - 24,537,341 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248075,684,661 - 5,691,456 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248075,683,454 - 5,706,823 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdk18
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1103,700,974 - 3,733,931 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cdk18
331 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:131
Count of miRNA genes:104
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000010976
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134373632747969993Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
RH141393  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21343,555,645 - 43,555,863 (+)MAPPERmRatBN7.2
Rnor_6.01348,893,571 - 48,893,788NCBIRnor6.0
Rnor_5.01353,963,531 - 53,963,748UniSTSRnor5.0
RGSC_v3.41344,995,346 - 44,995,563UniSTSRGSC3.4
Celera1343,893,067 - 43,893,284UniSTS
RH 3.4 Map13113.3UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 51 59 6 315 151 11 138 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000010976   ⟹   ENSRNOP00000010976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1346,108,911 - 46,128,700 (-)Ensembl
mRatBN7.2 Ensembl1343,556,748 - 43,565,655 (-)Ensembl
Rnor_6.0 Ensembl1348,893,412 - 48,927,483 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101022   ⟹   ENSRNOP00000089934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1346,108,911 - 46,140,865 (-)Ensembl
mRatBN7.2 Ensembl1343,556,748 - 43,588,525 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114199   ⟹   ENSRNOP00000095753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1346,108,911 - 46,119,312 (-)Ensembl
mRatBN7.2 Ensembl1343,556,748 - 43,565,477 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117493   ⟹   ENSRNOP00000078003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1346,108,911 - 46,140,086 (-)Ensembl
mRatBN7.2 Ensembl1343,556,748 - 43,576,595 (-)Ensembl
RefSeq Acc Id: NM_001100506   ⟹   NP_001093976
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,108,910 - 46,117,276 (-)NCBI
mRatBN7.21343,556,747 - 43,565,113 (-)NCBI
Rnor_6.01348,894,672 - 48,903,038 (-)NCBI
Rnor_5.01353,963,482 - 53,996,384 (-)NCBI
RGSC_v3.41344,996,447 - 45,004,813 (-)RGD
Celera1343,894,168 - 43,902,442 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249751   ⟹   XP_006249813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,107,763 - 46,134,399 (-)NCBI
mRatBN7.21343,555,597 - 43,582,206 (-)NCBI
Rnor_6.01348,893,525 - 48,920,975 (-)NCBI
Rnor_5.01353,963,482 - 53,996,384 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272067   ⟹   XP_063128137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,107,763 - 46,140,685 (-)NCBI
RefSeq Acc Id: XM_063272068   ⟹   XP_063128138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,107,763 - 46,140,705 (-)NCBI
RefSeq Acc Id: XM_063272070   ⟹   XP_063128140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,107,763 - 46,125,562 (-)NCBI
RefSeq Acc Id: XM_063272071   ⟹   XP_063128141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81346,107,763 - 46,139,366 (-)NCBI
RefSeq Acc Id: NP_001093976   ⟸   NM_001100506
- UniProtKB: O35832 (UniProtKB/Swiss-Prot),   Q641Z0 (UniProtKB/TrEMBL),   A0A0H2UHG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249813   ⟸   XM_006249751
- Peptide Label: isoform X3
- UniProtKB: O35832 (UniProtKB/Swiss-Prot),   Q641Z0 (UniProtKB/TrEMBL),   A0A0H2UHG4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010976   ⟸   ENSRNOT00000010976
Ensembl Acc Id: ENSRNOP00000078003   ⟸   ENSRNOT00000117493
Ensembl Acc Id: ENSRNOP00000089934   ⟸   ENSRNOT00000101022
Ensembl Acc Id: ENSRNOP00000095753   ⟸   ENSRNOT00000114199
RefSeq Acc Id: XP_063128138   ⟸   XM_063272068
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UHG4 (UniProtKB/TrEMBL),   A0A8I6A946 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128137   ⟸   XM_063272067
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHG4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128141   ⟸   XM_063272071
- Peptide Label: isoform X3
- UniProtKB: O35832 (UniProtKB/Swiss-Prot),   A0A0H2UHG4 (UniProtKB/TrEMBL),   Q641Z0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128140   ⟸   XM_063272070
- Peptide Label: isoform X3
- UniProtKB: O35832 (UniProtKB/Swiss-Prot),   A0A0H2UHG4 (UniProtKB/TrEMBL),   Q641Z0 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35832-F1-model_v2 AlphaFold O35832 1-451 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309523 AgrOrtholog
BioCyc Gene G2FUF-18327 BioCyc
Ensembl Genes ENSRNOG00000008137 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000101022 ENTREZGENE
  ENSRNOT00000114199 ENTREZGENE
  ENSRNOT00000117493 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7131722 IMAGE-MGC_LOAD
InterPro CDK UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:289019 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95190 IMAGE-MGC_LOAD
NCBI Gene 289019 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 18 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Cdk18 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008137 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A0H2UHG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZJM9_RAT UniProtKB/TrEMBL
  A0A8I6A946 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLS4_RAT UniProtKB/TrEMBL
  CDK18_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q641Z0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Cdk18  cyclin-dependent kinase 18  Pctk3  PCTAIRE protein kinase 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Pctk3  PCTAIRE protein kinase 3  Pctk3  PCTAIRE-motif protein kinase 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pctk3  PCTAIRE-motif protein kinase 3  Pctk3_predicted  PCTAIRE-motif protein kinase 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pctk3_predicted  PCTAIRE-motif protein kinase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED