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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309523
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk18
Name: cyclin-dependent kinase 18
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk18decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CDK18 mRNAPMID:30816183 PMID:32145629
Cdk18increases expressionEXP 6480464CTDbisphenol A results in increased expression of CDK18 mRNAPMID:25181051
Cdk18multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of CDK18 mRNAPMID:26496021
Cdk18increases methylationISOCdk18 (Mus musculus)6480464CTDbisphenol A results in increased methylation of CDK18 promoterPMID:27312807
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