Symbol:
Efnb2
Name:
ephrin B2
RGD ID:
1309497
Description:
Predicted to enable ephrin receptor binding activity. Involved in cellular response to lipopolysaccharide and presynapse assembly. Located in dendrite. Is active in glutamatergic synapse and presynaptic membrane. Biomarker of irritable bowel syndrome. Human ortholog(s) of this gene implicated in colon carcinoma; colorectal carcinoma; and esophagus squamous cell carcinoma. Orthologous to human EFNB2 (ephrin B2); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
ephrin-B2; LOC306636
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
EFNB2 (ephrin B2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB
Mus musculus (house mouse):
Efnb2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Efnb2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
EFNB2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
EFNB2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Efnb2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
EFNB2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
EFNB2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Efnb2 (ephrin B2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
EFNB2 (ephrin B2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Efnb2 (ephrin B2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
efnb2a (ephrin-B2a)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
efnb2b (ephrin-B2b)
Alliance
DIOPT (OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
efn-4
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
efn-2
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
Ephrin
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
vab-2
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
efn-3
Alliance
DIOPT (Ensembl Compara|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
efnb2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 87,485,215 - 87,529,224 (+) NCBI GRCr8 mRatBN7.2 16 80,783,389 - 80,827,420 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 80,783,417 - 80,824,391 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 86,062,447 - 86,103,384 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 89,515,058 - 89,556,010 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 84,759,477 - 84,800,448 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 86,631,151 - 86,672,050 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 86,631,064 - 86,675,049 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 86,044,304 - 86,085,652 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 86,187,639 - 86,228,023 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 16 86,173,265 - 86,214,062 (+) NCBI Celera 16 78,561,525 - 78,602,409 (+) NCBI Celera Cytogenetic Map 16 q12.5 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Efnb2 Rat (-)-epigallocatechin 3-gallate decreases expression ISO EFNB2 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of EFNB2 mRNA CTD PMID:16084531 Efnb2 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of EFNB2 mRNA CTD PMID:22079256 Efnb2 Rat 1,2-dimethylhydrazine affects expression ISO Efnb2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine affects the expression of EFNB2 mRNA CTD PMID:22206623 Efnb2 Rat 17beta-estradiol decreases expression ISO EFNB2 (Homo sapiens) 6480464 Estradiol results in decreased expression of EFNB2 mRNA CTD PMID:16474171 Efnb2 Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of EFNB2 mRNA CTD PMID:32741896 Efnb2 Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EFNB2 mRNA CTD PMID:32145629 Efnb2 Rat 17beta-estradiol multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of EFNB2 mRNA and [Progesterone co-treated with Estradiol] results in decreased expression of EFNB2 mRNA CTD PMID:17404688 and PMID:30165855 Efnb2 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of EFNB2 mRNA CTD PMID:32741896 Efnb2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Efnb2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EFNB2 mRNA CTD PMID:19933214 Efnb2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EFNB2 mRNA CTD PMID:33387578 Efnb2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EFNB2 mRNA CTD PMID:34747641 Efnb2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Efnb2 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Efnb2 Rat 2-methylcholine affects expression ISO EFNB2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of EFNB2 mRNA CTD PMID:21179406 Efnb2 Rat 4,4'-diaminodiphenylmethane decreases expression ISO Efnb2 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of EFNB2 mRNA CTD PMID:18648102 Efnb2 Rat 4,4'-sulfonyldiphenol increases expression ISO Efnb2 (Mus musculus) 6480464 bisphenol S results in increased expression of EFNB2 mRNA CTD PMID:30951980 Efnb2 Rat 4,4'-sulfonyldiphenol affects methylation ISO Efnb2 (Mus musculus) 6480464 bisphenol S affects the methylation of EFNB2 gene CTD PMID:31683443 Efnb2 Rat 4-hydroxyphenyl retinamide increases expression ISO Efnb2 (Mus musculus) 6480464 Fenretinide results in increased expression of EFNB2 mRNA CTD PMID:28973697 Efnb2 Rat 5-aza-2'-deoxycytidine decreases expression ISO Efnb2 (Mus musculus) 6480464 Decitabine results in decreased expression of EFNB2 mRNA CTD PMID:27915011 Efnb2 Rat 5-fluorouracil affects response to substance ISO EFNB2 (Homo sapiens) 6480464 EFNB2 protein affects the susceptibility to Fluorouracil CTD PMID:15352031 and PMID:16217747 Efnb2 Rat 5-fluorouracil decreases expression ISO EFNB2 (Homo sapiens) 6480464 Fluorouracil results in decreased expression of EFNB2 protein CTD PMID:15352031 Efnb2 Rat 7,12-dimethyltetraphene increases expression ISO Efnb2 (Mus musculus) 6480464 9 more ... CTD PMID:32553695 Efnb2 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of EFNB2 mRNA CTD PMID:28959563 Efnb2 Rat actinomycin D multiple interactions ISO EFNB2 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [Tretinoin results in increased expression of EFNB2 mRNA] CTD PMID:16688769 Efnb2 Rat afimoxifene increases expression ISO EFNB2 (Homo sapiens) 6480464 afimoxifene results in increased expression of EFNB2 mRNA CTD PMID:16849584 Efnb2 Rat all-trans-retinoic acid multiple interactions ISO EFNB2 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [Tretinoin results in increased expression of EFNB2 mRNA] CTD PMID:16688769 Efnb2 Rat all-trans-retinoic acid increases expression ISO EFNB2 (Homo sapiens) 6480464 Tretinoin results in increased expression of EFNB2 mRNA CTD PMID:16688769 more ... Efnb2 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of EFNB2 mRNA CTD PMID:30779732 Efnb2 Rat aristolochic acid A increases expression ISO EFNB2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of EFNB2 mRNA CTD PMID:33212167 Efnb2 Rat Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EFNB2 mRNA CTD PMID:34858468 Efnb2 Rat arsane decreases expression ISO Efnb2 (Mus musculus) 6480464 Arsenic results in decreased expression of EFNB2 mRNA CTD PMID:19654921 Efnb2 Rat arsenic atom decreases expression ISO Efnb2 (Mus musculus) 6480464 Arsenic results in decreased expression of EFNB2 mRNA CTD PMID:19654921 Efnb2 Rat arsenite(3-) increases expression ISO Efnb2 (Mus musculus) 6480464 arsenite results in increased expression of EFNB2 mRNA CTD PMID:33053406 Efnb2 Rat atrazine decreases expression ISO EFNB2 (Homo sapiens) 6480464 Atrazine results in decreased expression of EFNB2 mRNA CTD PMID:22378314 Efnb2 Rat benzo[a]pyrene increases expression ISO Efnb2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of EFNB2 mRNA CTD PMID:19770486 and PMID:32417428 Efnb2 Rat benzo[a]pyrene increases methylation ISO EFNB2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of EFNB2 3' UTR CTD PMID:27901495 Efnb2 Rat benzo[a]pyrene decreases expression ISO Efnb2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of EFNB2 mRNA CTD PMID:21569818 Efnb2 Rat benzo[a]pyrene diol epoxide I decreases expression ISO EFNB2 (Homo sapiens) 6480464 7 more ... CTD PMID:20018196 Efnb2 Rat Benzo[k]fluoranthene decreases expression ISO Efnb2 (Mus musculus) 6480464 benzo(k)fluoranthene results in decreased expression of EFNB2 mRNA CTD PMID:26377693 Efnb2 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Efnb2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of EFNB2 mRNA CTD PMID:34319233 Efnb2 Rat bisphenol A decreases expression ISO EFNB2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of EFNB2 mRNA CTD PMID:16474171 and PMID:29275510 Efnb2 Rat bisphenol A increases expression ISO Efnb2 (Mus musculus) 6480464 bisphenol A results in increased expression of EFNB2 mRNA CTD PMID:32156529 and PMID:35479511 Efnb2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EFNB2 mRNA CTD PMID:32145629 Efnb2 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EFNB2 gene CTD PMID:28505145 Efnb2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EFNB2 mRNA CTD PMID:25181051 more ... Efnb2 Rat bisphenol F increases expression ISO Efnb2 (Mus musculus) 6480464 bisphenol F results in increased expression of EFNB2 mRNA CTD PMID:30951980 Efnb2 Rat butanal increases expression ISO EFNB2 (Homo sapiens) 6480464 butyraldehyde results in increased expression of EFNB2 mRNA CTD PMID:26079696 Efnb2 Rat cadmium atom multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of EFNB2 mRNA CTD PMID:36114956 Efnb2 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of EFNB2 mRNA CTD PMID:33453195 Efnb2 Rat cadmium dichloride multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of EFNB2 mRNA CTD PMID:36114956 Efnb2 Rat calcitriol multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of EFNB2 mRNA CTD PMID:21592394 Efnb2 Rat calcitriol decreases expression ISO EFNB2 (Homo sapiens) 6480464 Calcitriol results in decreased expression of EFNB2 mRNA CTD PMID:16002434 and PMID:21592394 Efnb2 Rat carbon nanotube decreases expression ISO Efnb2 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Efnb2 Rat celastrol decreases expression ISO EFNB2 (Homo sapiens) 6480464 celastrol results in decreased expression of EFNB2 mRNA CTD PMID:17010675 Efnb2 Rat chlordecone increases expression ISO Efnb2 (Mus musculus) 6480464 Chlordecone results in increased expression of EFNB2 mRNA CTD PMID:29980752 Efnb2 Rat chloropicrin increases expression ISO EFNB2 (Homo sapiens) 6480464 chloropicrin results in increased expression of EFNB2 mRNA CTD PMID:26352163 Efnb2 Rat chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of EFNB2 mRNA CTD PMID:34858468 Efnb2 Rat choline multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNB2 gene CTD PMID:20938992 Efnb2 Rat chromium(6+) affects expression ISO Efnb2 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of EFNB2 mRNA CTD PMID:28472532 Efnb2 Rat cisplatin multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of EFNB2 mRNA CTD PMID:27392435 Efnb2 Rat cisplatin decreases expression ISO EFNB2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of EFNB2 mRNA CTD PMID:27392435 Efnb2 Rat cocaine increases expression EXP 6480464 Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 Efnb2 Rat copper atom multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of EFNB2 mRNA CTD PMID:20971185 Efnb2 Rat copper atom increases expression EXP 6480464 Copper results in increased expression of EFNB2 mRNA CTD PMID:30556269 Efnb2 Rat copper(0) multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of EFNB2 mRNA CTD PMID:20971185 Efnb2 Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of EFNB2 mRNA CTD PMID:30556269 Efnb2 Rat copper(II) chloride increases expression ISO EFNB2 (Homo sapiens) 6480464 cupric chloride results in increased expression of EFNB2 mRNA CTD PMID:38568856 Efnb2 Rat coumestrol multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 Efnb2 Rat coumestrol decreases expression ISO EFNB2 (Homo sapiens) 6480464 Coumestrol results in decreased expression of EFNB2 mRNA CTD PMID:19167446 Efnb2 Rat dibenz[a,h]anthracene decreases expression ISO Efnb2 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 Efnb2 Rat dorsomorphin multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EFNB2 mRNA CTD PMID:27188386 Efnb2 Rat Enterolactone multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EFNB2 mRNA CTD PMID:19167446 Efnb2 Rat entinostat decreases expression ISO EFNB2 (Homo sapiens) 6480464 entinostat results in decreased expression of EFNB2 mRNA CTD PMID:26272509 Efnb2 Rat entinostat multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EFNB2 mRNA CTD PMID:27188386 Efnb2 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of EFNB2 mRNA CTD PMID:24793618 Efnb2 Rat folic acid multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNB2 gene CTD PMID:20938992 Efnb2 Rat formaldehyde decreases expression ISO EFNB2 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of EFNB2 mRNA CTD PMID:20655997 Efnb2 Rat furan decreases expression EXP 6480464 furan results in decreased expression of EFNB2 mRNA CTD PMID:25539665 Efnb2 Rat gedunin decreases expression ISO EFNB2 (Homo sapiens) 6480464 gedunin results in decreased expression of EFNB2 mRNA CTD PMID:17010675 Efnb2 Rat genistein decreases expression ISO EFNB2 (Homo sapiens) 6480464 Genistein results in decreased expression of EFNB2 mRNA CTD PMID:16474171 and PMID:26865667 Efnb2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of EFNB2 mRNA CTD PMID:33387578 Efnb2 Rat hydrogen peroxide affects expression ISO EFNB2 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of EFNB2 mRNA CTD PMID:20044591 Efnb2 Rat isobutanol multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of EFNB2 mRNA CTD PMID:29432896 Efnb2 Rat L-methionine multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of EFNB2 gene CTD PMID:20938992 Efnb2 Rat lead diacetate increases expression ISO EFNB2 (Homo sapiens) 6480464 lead acetate results in increased expression of EFNB2 mRNA CTD PMID:38568856 Efnb2 Rat Licochalcone B increases expression ISO EFNB2 (Homo sapiens) 6480464 licochalcone B results in increased expression of EFNB2 mRNA CTD PMID:33647349 Efnb2 Rat lithocholic acid multiple interactions ISO EFNB2 (Homo sapiens) 6480464 Lithocholic Acid inhibits the reaction [[EPHB4 protein binds to EFNB2 protein] which results in increased phosphorylation of EPHB4 protein] CTD PMID:21479221 Efnb2 Rat menadione decreases expression ISO Efnb2 (Mus musculus) 6480464 Vitamin K 3 results in decreased expression of EFNB2 mRNA CTD PMID:25270620 Efnb2 Rat methylisothiazolinone increases expression ISO EFNB2 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of EFNB2 mRNA CTD PMID:31629900 Efnb2 Rat mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of EFNB2 mRNA CTD PMID:16809437 Efnb2 Rat N-acetyl-L-cysteine decreases expression ISO EFNB2 (Homo sapiens) 6480464 Acetylcysteine results in decreased expression of EFNB2 mRNA CTD PMID:16084531 Efnb2 Rat nitrofen increases expression EXP 6480464 nitrofen results in increased expression of EFNB2 mRNA and nitrofen results in increased expression of EFNB2 protein CTD PMID:30106123 Efnb2 Rat ozone decreases expression ISO Efnb2 (Mus musculus) 6480464 Ozone results in decreased expression of EFNB2 mRNA CTD PMID:12763052 Efnb2 Rat ozone multiple interactions ISO Efnb2 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EFNB2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of EFNB2 mRNA CTD PMID:34911549 Efnb2 Rat paracetamol increases expression ISO EFNB2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of EFNB2 mRNA CTD PMID:21420995 Efnb2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of EFNB2 mRNA CTD PMID:33387578 Efnb2 Rat pentanal increases expression ISO EFNB2 (Homo sapiens) 6480464 pentanal results in increased expression of EFNB2 mRNA CTD PMID:26079696 Efnb2 Rat phenobarbital affects methylation ISO Efnb2 (Mus musculus) 6480464 Phenobarbital affects the methylation of EFNB2 gene CTD PMID:19233941 Efnb2 Rat pirinixic acid increases expression ISO Efnb2 (Mus musculus) 6480464 pirinixic acid results in increased expression of EFNB2 mRNA CTD PMID:23811191 Efnb2 Rat potassium chromate increases expression ISO EFNB2 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of EFNB2 mRNA CTD PMID:22079256 Efnb2 Rat potassium chromate multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of EFNB2 mRNA CTD PMID:22079256 Efnb2 Rat progesterone multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of EFNB2 mRNA CTD PMID:17404688 Efnb2 Rat progesterone decreases expression ISO EFNB2 (Homo sapiens) 6480464 Progesterone results in decreased expression of EFNB2 mRNA CTD PMID:17404688 Efnb2 Rat propanal increases expression ISO EFNB2 (Homo sapiens) 6480464 propionaldehyde results in increased expression of EFNB2 mRNA CTD PMID:26079696 Efnb2 Rat quercetin increases expression ISO EFNB2 (Homo sapiens) 6480464 Quercetin results in increased expression of EFNB2 mRNA CTD PMID:21632981 Efnb2 Rat resveratrol multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of EFNB2 mRNA CTD PMID:19167446 Efnb2 Rat SB 431542 increases expression ISO EFNB2 (Homo sapiens) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of EFNB2 protein CTD PMID:25670856 Efnb2 Rat SB 431542 multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EFNB2 mRNA CTD PMID:27188386 Efnb2 Rat silicon dioxide increases expression ISO EFNB2 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of EFNB2 mRNA and Silicon Dioxide results in increased expression of EFNB2 mRNA CTD PMID:23806026 more ... Efnb2 Rat sodium arsenite decreases expression ISO EFNB2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of EFNB2 mRNA CTD PMID:12727804 more ... Efnb2 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of EFNB2 mRNA CTD PMID:35314868 Efnb2 Rat streptozocin affects expression ISO Efnb2 (Mus musculus) 6480464 Streptozocin affects the expression of EFNB2 mRNA CTD PMID:26073000 Efnb2 Rat sulforaphane decreases expression ISO EFNB2 (Homo sapiens) 6480464 sulforaphane results in decreased expression of EFNB2 mRNA CTD PMID:31838189 Efnb2 Rat sunitinib increases expression ISO EFNB2 (Homo sapiens) 6480464 Sunitinib results in increased expression of EFNB2 mRNA CTD PMID:31533062 Efnb2 Rat testosterone multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of EFNB2 mRNA CTD PMID:21592394 Efnb2 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of EFNB2 mRNA CTD PMID:32741896 Efnb2 Rat testosterone decreases expression ISO EFNB2 (Homo sapiens) 6480464 Testosterone results in decreased expression of EFNB2 mRNA CTD PMID:21592394 Efnb2 Rat testosterone enanthate affects expression ISO EFNB2 (Homo sapiens) 6480464 testosterone enanthate affects the expression of EFNB2 mRNA CTD PMID:17440010 Efnb2 Rat tetrachloromethane increases expression ISO Efnb2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of EFNB2 mRNA CTD PMID:17484886 Efnb2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of EFNB2 mRNA CTD PMID:34492290 Efnb2 Rat thiram increases expression ISO EFNB2 (Homo sapiens) 6480464 Thiram results in increased expression of EFNB2 mRNA CTD PMID:38568856 Efnb2 Rat titanium dioxide increases methylation ISO Efnb2 (Mus musculus) 6480464 titanium dioxide results in increased methylation of EFNB2 promoter CTD PMID:35295148 Efnb2 Rat titanium dioxide decreases methylation ISO Efnb2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of EFNB2 promoter CTD PMID:35295148 Efnb2 Rat trichostatin A increases expression ISO EFNB2 (Homo sapiens) 6480464 trichostatin A results in increased expression of EFNB2 mRNA CTD PMID:24935251 Efnb2 Rat trimellitic anhydride decreases expression ISO Efnb2 (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of EFNB2 mRNA CTD PMID:19042947 Efnb2 Rat triptonide increases expression ISO Efnb2 (Mus musculus) 6480464 triptonide results in increased expression of EFNB2 mRNA CTD PMID:33045310 Efnb2 Rat tris(2-butoxyethyl) phosphate affects expression ISO EFNB2 (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate affects the expression of EFNB2 mRNA CTD PMID:29024780 Efnb2 Rat troglitazone increases expression ISO Efnb2 (Mus musculus) 6480464 troglitazone results in increased expression of EFNB2 mRNA CTD PMID:17569031 Efnb2 Rat tunicamycin increases expression ISO Efnb2 (Mus musculus) 6480464 Tunicamycin results in increased expression of EFNB2 mRNA CTD PMID:17127020 Efnb2 Rat tunicamycin decreases expression ISO EFNB2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of EFNB2 mRNA CTD PMID:22378314 Efnb2 Rat urethane increases expression ISO EFNB2 (Homo sapiens) 6480464 Urethane results in increased expression of EFNB2 mRNA CTD PMID:28818685 Efnb2 Rat valproic acid affects expression ISO EFNB2 (Homo sapiens) 6480464 Valproic Acid affects the expression of EFNB2 mRNA CTD PMID:25979313 Efnb2 Rat valproic acid increases expression ISO EFNB2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of EFNB2 mRNA CTD PMID:24383497 more ... Efnb2 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of EFNB2 mRNA CTD PMID:19015723 Efnb2 Rat zinc atom multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EFNB2 mRNA CTD PMID:18593933 Efnb2 Rat zinc(0) multiple interactions ISO EFNB2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EFNB2 mRNA CTD PMID:18593933 Efnb2 Rat zoledronic acid decreases expression ISO EFNB2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of EFNB2 mRNA CTD PMID:24714768
Imported Annotations - PID (archival)
(-)-epigallocatechin 3-gallate (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2-methylcholine (ISO) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-aza-2'-deoxycytidine (ISO) 5-fluorouracil (ISO) 7,12-dimethyltetraphene (ISO) acrylamide (EXP) actinomycin D (ISO) afimoxifene (ISO) all-trans-retinoic acid (ISO) amphetamine (EXP) aristolochic acid A (ISO) Aroclor 1254 (EXP) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) atrazine (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) Benzo[k]fluoranthene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) butanal (ISO) cadmium atom (ISO) cadmium dichloride (EXP,ISO) calcitriol (ISO) carbon nanotube (ISO) celastrol (ISO) chlordecone (ISO) chloropicrin (ISO) chlorpyrifos (EXP) choline (ISO) chromium(6+) (ISO) cisplatin (ISO) cocaine (EXP) copper atom (EXP,ISO) copper(0) (EXP,ISO) copper(II) chloride (ISO) coumestrol (ISO) dibenz[a,h]anthracene (ISO) dorsomorphin (ISO) Enterolactone (ISO) entinostat (ISO) flutamide (EXP) folic acid (ISO) formaldehyde (ISO) furan (EXP) gedunin (ISO) genistein (ISO) gentamycin (EXP) hydrogen peroxide (ISO) isobutanol (ISO) L-methionine (ISO) lead diacetate (ISO) Licochalcone B (ISO) lithocholic acid (ISO) menadione (ISO) methylisothiazolinone (ISO) mono(2-ethylhexyl) phthalate (EXP) N-acetyl-L-cysteine (ISO) nitrofen (EXP) ozone (ISO) paracetamol (EXP,ISO) pentanal (ISO) phenobarbital (ISO) pirinixic acid (ISO) potassium chromate (ISO) progesterone (ISO) propanal (ISO) quercetin (ISO) resveratrol (ISO) SB 431542 (ISO) silicon dioxide (ISO) sodium arsenite (EXP,ISO) streptozocin (ISO) sulforaphane (ISO) sunitinib (ISO) testosterone (EXP,ISO) testosterone enanthate (ISO) tetrachloromethane (ISO) thioacetamide (EXP) thiram (ISO) titanium dioxide (ISO) trichostatin A (ISO) trimellitic anhydride (ISO) triptonide (ISO) tris(2-butoxyethyl) phosphate (ISO) troglitazone (ISO) tunicamycin (ISO) urethane (ISO) valproic acid (ISO) vinclozolin (EXP) zinc atom (ISO) zinc(0) (ISO) zoledronic acid (ISO)
Biological Process
adherens junction organization (IEA,ISO) animal organ morphogenesis (IEA,ISO) blood vessel morphogenesis (IEA,ISO) cell adhesion (IEA,ISO) cell differentiation (IEA) cell migration involved in sprouting angiogenesis (IEA,ISO) cellular response to lipopolysaccharide (IEP) ephrin receptor signaling pathway (IEA,ISO) keratinocyte proliferation (IEA,ISO) lymph vessel development (IEA,ISO) negative regulation of keratinocyte proliferation (IEA,ISO) negative regulation of neuron projection development (IEA,ISO) nephric duct morphogenesis (IEA,ISO) nervous system development (IEA) positive regulation of aorta morphogenesis (IEA,ISO) positive regulation of cardiac muscle cell differentiation (IEA,ISO) positive regulation of cell population proliferation (IEA,ISO) presynapse assembly (IDA,IMP) regulation of chemotaxis (IEA,ISO) regulation of postsynaptic membrane neurotransmitter receptor levels (IEA,ISO) regulation of postsynaptic neurotransmitter receptor internalization (IEA,ISO) T cell costimulation (IEA,ISO) venous blood vessel morphogenesis (IEA,ISO)
1.
DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.
Alam SK, etal., Cell Death Differ. 2016 Apr;23(4):707-22. doi: 10.1038/cdd.2015.133. Epub 2015 Oct 23.
2.
Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation.
Aoto J, etal., J Neurosci. 2007 Jul 11;27(28):7508-19. doi: 10.1523/JNEUROSCI.0705-07.2007.
3.
Ephrin-B2 and EphB2 regulation of astrocyte-meningeal fibroblast interactions in response to spinal cord lesions in adult rats.
Bundesen LQ, etal., J Neurosci. 2003 Aug 27;23(21):7789-800.
4.
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.
Cissé M, etal., Nature. 2011 Jan 6;469(7328):47-52. doi: 10.1038/nature09635. Epub 2010 Nov 28.
5.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
7.
Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer.
Kataoka H, etal., J Cancer Res Clin Oncol. 2002 Jul;128(7):343-8. doi: 10.1007/s00432-002-0355-0. Epub 2002 Jun 26.
8.
Increased EphB2 expression predicts cholangiocarcinoma metastasis.
Khansaard W, etal., Tumour Biol. 2014 Oct;35(10):10031-41. doi: 10.1007/s13277-014-2295-0. Epub 2014 Jul 11.
9.
Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer.
Liu W, etal., Br J Cancer. 2004 Apr 19;90(8):1620-6. doi: 10.1038/sj.bjc.6601723.
10.
Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1.
McClelland AC, etal., Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20487-92. doi: 10.1073/pnas.0811862106. Epub 2009 Nov 13.
11.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
12.
Expression levels of EPHB4, EFNB2 and caspase-8 are associated with clinicopathological features and progression of esophageal squamous cell cancer.
Ni Q, etal., Oncol Lett. 2020 Jan;19(1):917-929. doi: 10.3892/ol.2019.11160. Epub 2019 Nov 28.
13.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14.
GOA pipeline
RGD automated data pipeline
15.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
16.
BIBF1120 (Vargatef) Inhibits Preretinal Neovascularization and Enhances Normal Vascularization in a Model of Vasoproliferative Retinopathy.
Rivera JC, etal., Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7897-907. doi: 10.1167/iovs.15-17146.
17.
Downregulation of the endothelial genes Notch1 and ephrinB2 in patients with nodular regenerative hyperplasia.
Rothweiler S, etal., Liver Int. 2014 Apr;34(4):594-603. doi: 10.1111/liv.12261. Epub 2013 Jul 21.
18.
Ephrin-B2 reverse signaling regulates progression and lymph node metastasis of oral squamous cell carcinoma.
Sasabe E, etal., PLoS One. 2017 Nov 30;12(11):e0188965. doi: 10.1371/journal.pone.0188965. eCollection 2017.
19.
Arterialization and anomalous vein wall remodeling in varicose veins is associated with upregulated FoxC2-Dll4 pathway.
Surendran S, etal., Lab Invest. 2016 Apr;96(4):399-408. doi: 10.1038/labinvest.2015.167. Epub 2016 Jan 25.
20.
Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma.
Tachibana M, etal., Dig Liver Dis. 2007 Aug;39(8):725-32. doi: 10.1016/j.dld.2007.05.013. Epub 2007 Jul 3.
21.
EphB2 knockdown decreases the formation of astroglial-fibrotic scars to promote nerve regeneration after spinal cord injury in rats.
Wu J, etal., CNS Neurosci Ther. 2021 Jun;27(6):714-724. doi: 10.1111/cns.13641. Epub 2021 Apr 1.
22.
EphrinB2/ephB2-mediated myenteric synaptic plasticity: mechanisms underlying the persistent muscle hypercontractility and pain in postinfectious IBS.
Zhang L, etal., FASEB J. 2019 Dec;33(12):13644-13659. doi: 10.1096/fj.201901192R. Epub 2019 Oct 25.
23.
[The expressions of EphrinB2 and VEGF in nasopharyngeal carcinoma and their clinical significance].
Zhang R, etal., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Feb;27(4):178-80.
Efnb2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 87,485,215 - 87,529,224 (+) NCBI GRCr8 mRatBN7.2 16 80,783,389 - 80,827,420 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 80,783,417 - 80,824,391 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 86,062,447 - 86,103,384 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 89,515,058 - 89,556,010 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 84,759,477 - 84,800,448 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 86,631,151 - 86,672,050 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 86,631,064 - 86,675,049 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 86,044,304 - 86,085,652 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 86,187,639 - 86,228,023 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 16 86,173,265 - 86,214,062 (+) NCBI Celera 16 78,561,525 - 78,602,409 (+) NCBI Celera Cytogenetic Map 16 q12.5 NCBI
EFNB2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 13 106,489,745 - 106,535,662 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 13 106,489,745 - 106,535,662 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 13 107,142,093 - 107,188,010 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 13 105,940,094 - 105,985,338 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 13 105,940,097 - 105,985,338 NCBI Celera 13 87,986,327 - 88,031,570 (-) NCBI Celera Cytogenetic Map 13 q33.3 NCBI HuRef 13 87,733,581 - 87,778,804 (-) NCBI HuRef CHM1_1 13 107,110,751 - 107,156,066 (-) NCBI CHM1_1 T2T-CHM13v2.0 13 105,710,156 - 105,756,072 (-) NCBI T2T-CHM13v2.0
Efnb2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 8 8,667,235 - 8,711,242 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 8 8,667,434 - 8,711,242 (-) Ensembl GRCm39 Ensembl GRCm38 8 8,617,235 - 8,661,242 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 8 8,617,434 - 8,661,242 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 8 8,617,439 - 8,660,773 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 8 8,617,406 - 8,660,745 (-) NCBI MGSCv36 mm8 Celera 8 8,790,063 - 8,833,410 (-) NCBI Celera Cytogenetic Map 8 A1.1 NCBI cM Map 8 3.42 NCBI
Efnb2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955404 5,000,906 - 5,030,126 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955404 5,000,906 - 5,030,068 (+) NCBI ChiLan1.0 ChiLan1.0
EFNB2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 14 107,986,859 - 108,032,680 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 13 106,667,225 - 106,713,015 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 13 87,629,831 - 87,675,652 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 13 106,770,296 - 106,815,542 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 13 106,770,296 - 106,815,548 (-) Ensembl panpan1.1 panPan2
EFNB2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 22 55,567,992 - 55,609,210 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 22 55,566,039 - 55,609,443 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 22 55,325,721 - 55,366,922 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 22 56,079,969 - 56,121,281 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 22 56,078,458 - 56,121,514 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 22 55,672,831 - 55,714,054 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 22 55,659,581 - 55,700,849 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 22 55,698,309 - 55,739,598 (-) NCBI UU_Cfam_GSD_1.0
Efnb2 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404945 190,770,785 - 190,813,404 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936472 5,138,745 - 5,181,668 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936472 5,138,751 - 5,181,630 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
EFNB2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 11 74,186,640 - 74,233,354 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 11 74,188,337 - 74,232,768 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 11 81,565,082 - 81,609,512 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
EFNB2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 3 84,904,421 - 84,949,292 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 3 84,904,435 - 84,949,465 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666046 41,467,321 - 41,512,883 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Efnb2
.
Predicted Target Of
Count of predictions: 61 Count of miRNA genes: 56 Interacting mature miRNAs: 61 Transcripts: ENSRNOT00000019675 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2300163 Bmd64 Bone mineral density QTL 64 5.3 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 16 37752156 82752156 Rat 7411648 Foco22 Food consumption QTL 22 15 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 16 52726464 84729064 Rat 2293690 Bss45 Bone structure and strength QTL 45 5.13 0.0001 lumbar vertebra morphology trait (VT:0010494) lumbar vertebra cortical cross-sectional area (CMO:0001690) 16 37752156 82752156 Rat 8694364 Abfw7 Abdominal fat weight QTL 7 12.22 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 16 52726464 84729064 Rat 8694429 Bw164 Body weight QTL 164 5 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 16 52726464 84729064 Rat 7205510 Activ5 Activity QTL 5 3.78 0.00028 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 16 42396345 84729064 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor diameter (CMO:0001889) 16 17696791 82635055 Rat 631525 Pia14 Pristane induced arthritis QTL 14 4.4 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 16 55711087 83402471 Rat
RH143318
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 80,826,828 - 80,827,118 (+) MAPPER mRatBN7.2 Rnor_6.0 16 86,674,488 - 86,674,777 NCBI Rnor6.0 Rnor_5.0 16 86,088,090 - 86,088,379 UniSTS Rnor5.0 Celera 16 78,604,847 - 78,605,136 UniSTS RH 3.4 Map 16 788.5 UniSTS Cytogenetic Map 16 q12.5 UniSTS
BE098957
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 80,806,455 - 80,806,647 (+) MAPPER mRatBN7.2 Rnor_6.0 16 86,653,441 - 86,653,632 NCBI Rnor6.0 Rnor_5.0 16 86,067,043 - 86,067,234 UniSTS Rnor5.0 RGSC_v3.4 16 86,210,572 - 86,210,763 UniSTS RGSC3.4 Celera 16 78,584,479 - 78,584,670 UniSTS RH 3.4 Map 16 787.5 UniSTS Cytogenetic Map 16 q12.5 UniSTS
Efnb2
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 80,825,304 - 80,825,530 (+) MAPPER mRatBN7.2 Rnor_6.0 16 86,672,964 - 86,673,189 NCBI Rnor6.0 Rnor_5.0 16 86,086,566 - 86,086,791 UniSTS Rnor5.0 RGSC_v3.4 16 86,229,195 - 86,229,420 UniSTS RGSC3.4 Celera 16 78,603,323 - 78,603,548 UniSTS Cytogenetic Map 16 q12.5 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000019675 ⟹ ENSRNOP00000019675
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 16 86,631,064 - 86,675,049 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000093850 ⟹ ENSRNOP00000093640
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 80,783,417 - 80,824,391 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000103879 ⟹ ENSRNOP00000084601
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 80,783,417 - 80,824,391 (+) Ensembl
RefSeq Acc Id:
NM_001107328 ⟹ NP_001100798
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 87,485,215 - 87,526,184 (+) NCBI mRatBN7.2 16 80,783,417 - 80,824,391 (+) NCBI Rnor_6.0 16 86,631,151 - 86,672,050 (+) NCBI Rnor_5.0 16 86,044,304 - 86,085,652 (+) NCBI RGSC_v3.4 16 86,187,639 - 86,228,023 (+) RGD Celera 16 78,561,525 - 78,602,409 (+) RGD
Sequence:
GGTTTGGCCATGGCCATGGCCCGGTCCAGGAGGGACTCTGTGTGGAAGTACTGTTGGGGACTTTTGATGGTTTTGTGCAGAACTGCGATCTCCAGATCGATAGTTCTAGAGCCTATCTACTGGAATTC
hide sequence
RefSeq Acc Id:
XM_039094605 ⟹ XP_038950533
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 87,485,221 - 87,529,224 (+) NCBI mRatBN7.2 16 80,783,389 - 80,827,420 (+) NCBI
RefSeq Acc Id:
NP_001100798 ⟸ NM_001107328
- UniProtKB:
B2B9A9 (UniProtKB/TrEMBL), A6IWT6 (UniProtKB/TrEMBL), A0A8I5ZYG5 (UniProtKB/TrEMBL)
- Sequence:
MAMARSRRDSVWKYCWGLLMVLCRTAISRSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKEQADRCTIKKENTPLLNCARPDQDVKFTIKFQEFSPNLWGLE
hide sequence
Ensembl Acc Id:
ENSRNOP00000019675 ⟸ ENSRNOT00000019675
RefSeq Acc Id:
XP_038950533 ⟸ XM_039094605
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I6AJ66 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000093640 ⟸ ENSRNOT00000093850
Ensembl Acc Id:
ENSRNOP00000084601 ⟸ ENSRNOT00000103879
RGD ID: 13700251 Promoter ID: EPDNEW_R10775 Type: initiation region Name: Efnb2_1 Description: ephrin B2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 16 86,630,974 - 86,631,034 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2008-04-30
Efnb2
ephrin B2
Efnb2_predicted
ephrin B2 (predicted)
'predicted' is removed
2292626 APPROVED
2005-01-12
Efnb2_predicted
ephrin B2 (predicted)
Symbol and Name status set to approved
70820 APPROVED
