Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of KTN1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ktn1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KTN1 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of KTN1 mRNA | CTD | PMID:25380136 | 17alpha-ethynylestradiol | multiple interactions | ISO | Ktn1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KTN1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of KTN1 mRNA | CTD | PMID:19167446 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ktn1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KTN1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KTN1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KTN1 mRNA | CTD | PMID:18691609 more ... | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of KTN1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of KTN1 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of KTN1 protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of KTN1 mRNA | CTD | PMID:24780913 | acrolein | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of KTN1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of KTN1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of KTN1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | KTN1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of KTN1 gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of KTN1 mRNA | CTD | PMID:30928695 | alpha-pinene | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of KTN1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of KTN1 mRNA | CTD | PMID:32699268 | aristolochic acid A | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KTN1 mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KTN1 protein | CTD | PMID:25419056 | atrazine | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of KTN1 mRNA | CTD | PMID:22378314 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of KTN1 gene | CTD | PMID:35440735 | azoxystrobin | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of KTN1 mRNA | CTD | PMID:33512557 | benzatropine | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein | CTD | PMID:34122009 | benzatropine | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Benztropine results in decreased expression of KTN1 protein | CTD | PMID:34122009 | benzo[a]pyrene | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of KTN1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | KTN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KTN1 intron and Benzo(a)pyrene affects the methylation of KTN1 promoter | CTD | PMID:27901495 and PMID:30157460 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KTN1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of KTN1 protein | CTD | PMID:34186270 | bisphenol A | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of KTN1 protein | CTD | PMID:33376534 | bisphenol A | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of KTN1 mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of KTN1 mRNA | CTD | PMID:30816183 | Bisphenol B | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of KTN1 protein | CTD | PMID:34186270 | bisphenol F | increases methylation | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol F results in increased methylation of KTN1 gene | CTD | PMID:31601247 | bisphenol F | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of KTN1 protein | CTD | PMID:34186270 | bortezomib | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of KTN1 mRNA | CTD | PMID:20977926 | caffeine | decreases phosphorylation | ISO | KTN1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of KTN1 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of KTN1 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KTN1 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of KTN1 mRNA | CTD | PMID:37019170 | ciguatoxin CTX1B | affects expression | ISO | Ktn1 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of KTN1 mRNA | CTD | PMID:18353800 | clorgyline | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of KTN1 mRNA | CTD | PMID:19691856 | coumestrol | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of KTN1 mRNA | CTD | PMID:19167446 | Cuprizon | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein | CTD | PMID:34122009 | DDT | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | DDT results in increased expression of KTN1 mRNA | CTD | PMID:25014179 | decabromodiphenyl ether | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of KTN1 protein | CTD | PMID:31675489 | deguelin | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | deguelin results in increased expression of KTN1 mRNA | CTD | PMID:33512557 | diarsenic trioxide | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of KTN1 protein | CTD | PMID:25419056 | dicrotophos | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of KTN1 mRNA | CTD | PMID:28302478 | dioxygen | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of KTN1 mRNA | CTD | PMID:24205000 | disodium selenite | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of KTN1 mRNA | CTD | PMID:18175754 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of KTN1 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KTN1 mRNA | CTD | PMID:27188386 | doxorubicin | affects expression | ISO | KTN1 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of KTN1 protein | CTD | PMID:29385562 | elemental selenium | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | elemental selenium | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | enzyme inhibitor | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of KTN1 protein | CTD | PMID:23301498 | ethanol | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Ethanol results in decreased expression of KTN1 mRNA | CTD | PMID:29018328 | ethanol | affects splicing | ISO | Ktn1 (Mus musculus) | 6480464 | Ethanol affects the splicing of KTN1 mRNA | CTD | PMID:30319688 | ethanol | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Ethanol results in increased expression of KTN1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Ktn1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KTN1 mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | KTN1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of KTN1 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of KTN1 mRNA | CTD | PMID:33387578 | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of KTN1 mRNA | CTD | PMID:24395379 | ivermectin | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of KTN1 protein | CTD | PMID:32959892 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of KTN1 mRNA | CTD | PMID:20080153 | kojic acid | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of KTN1 mRNA | CTD | PMID:16595896 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of KTN1 mRNA | CTD | PMID:30467583 | methyl methanesulfonate | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of KTN1 mRNA | CTD | PMID:23649840 | ozone | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of KTN1 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Ktn1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of KTN1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KTN1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of KTN1 mRNA | CTD | PMID:27153767 | phenethyl isothiocyanate | decreases expression | EXP | | 6480464 | phenethyl isothiocyanate results in decreased expression of KTN1 mRNA | CTD | PMID:17616710 | phenylmercury acetate | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of KTN1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KTN1 mRNA | CTD | PMID:27188386 | picoxystrobin | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of KTN1 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KTN1 mRNA | CTD | PMID:27188386 | selenium atom | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | selenium atom | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | senecionine | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | senecionine results in decreased expression of KTN1 protein | CTD | PMID:35357534 | sunitinib | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of KTN1 mRNA | CTD | PMID:31533062 | tert-butyl hydroperoxide | increases expression | ISO | KTN1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of KTN1 mRNA | CTD | PMID:15336504 | tetrachloromethane | affects expression | ISO | Ktn1 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of KTN1 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of KTN1 mRNA | CTD | PMID:27339419 and PMID:31919559 | thapsigargin | increases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of KTN1 protein | CTD | PMID:24648495 | triptonide | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | triptonide results in decreased expression of KTN1 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of KTN1 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | ISO | Ktn1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of KTN1 mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | KTN1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of KTN1 gene | CTD | PMID:29154799 | vitamin E | multiple interactions | ISO | KTN1 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | vitamin E | decreases expression | ISO | KTN1 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of KTN1 mRNA | CTD | PMID:19244175 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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