Usp5 (ubiquitin specific peptidase 5) - Rat Genome Database

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Gene: Usp5 (ubiquitin specific peptidase 5) Rattus norvegicus
Analyze
Symbol: Usp5
Name: ubiquitin specific peptidase 5
RGD ID: 1308438
Description: Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in several processes, including protein K48-linked deubiquitination; regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation protein catabolic process at presynapse. Predicted to act upstream of or within several processes, including negative regulation of T cell activation; negative regulation of T cell mediated immune response to tumor cell; and positive regulation of macromolecule biosynthetic process. Predicted to be located in presynapse. Predicted to be active in cytosol and nucleus. Orthologous to human USP5 (ubiquitin specific peptidase 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911959; LOC297593; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin carboxyl-terminal hydrolase 5-like; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,305,927 - 159,321,345 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4159,305,938 - 159,320,956 (-)EnsemblGRCr8
mRatBN7.24157,619,663 - 157,634,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)Ensemblrn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-cyanoalanine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
acetamide  (EXP)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bortezomib  (ISO)
Brodifacoum  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
chlordecone  (ISO)
clozapine  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
GSK-J4  (ISO)
haloperidol  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
methylazoxymethanol  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitrates  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
warfarin  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
cytoplasmic stress granule  (IEA)
cytosol  (IBA)
nucleus  (IBA,IEA)
presynapse  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19098288   PMID:19182904   PMID:22871113   PMID:23375434   PMID:24424410   PMID:28131823  


Genomics

Comparative Map Data
Usp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,305,927 - 159,321,345 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4159,305,938 - 159,320,956 (-)EnsemblGRCr8
mRatBN7.24157,619,663 - 157,634,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)Ensemblrn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
USP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,852,150 - 6,866,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,852,122 - 6,866,632 (+)Ensemblhg38GRCh38
GRCh37126,961,314 - 6,975,796 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,831,546 - 6,846,057 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34126,831,583 - 6,846,054NCBI
Celera128,578,571 - 8,593,082 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,815,013 - 6,829,524 (+)NCBIHuRef
CHM1_1126,960,283 - 6,974,794 (+)NCBICHM1_1
T2T-CHM13v2.0126,861,449 - 6,875,929 (+)NCBIT2T-CHM13v2.0
Usp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,791,982 - 124,806,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,791,982 - 124,806,447 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386124,815,019 - 124,829,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,815,019 - 124,829,484 (-)Ensemblmm10GRCm38
MGSCv376124,765,037 - 124,779,465 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366124,780,638 - 124,795,066 (-)NCBIMGSCv36mm8
Celera6126,491,148 - 126,505,576 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Usp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,451,622 - 4,466,832 (+)Ensembl
ChiLan1.0NW_0049554134,451,530 - 4,466,832 (+)NCBIChiLan1.0ChiLan1.0
USP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,414,488 - 12,429,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,411,246 - 12,426,552 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,895,416 - 6,909,936 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)EnsemblpanPan2panpan1.1
USP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,158,850 - 38,172,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,158,834 - 38,172,071 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha278,444,116 - 8,457,897 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02738,511,741 - 38,525,542 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,511,746 - 38,524,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,385,805 - 38,399,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,426,829 - 38,440,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,922,848 - 7,936,630 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Usp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,284,676 - 102,298,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709952,182 - 966,498 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936709952,225 - 966,429 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,843,745 - 63,858,716 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1563,843,742 - 63,858,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,279,250 - 66,294,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,885,401 - 6,899,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,885,311 - 6,898,442 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660631,323,576 - 1,338,147 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,519,113 - 3,532,687 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248603,519,106 - 3,532,690 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Usp5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1623,062,327 - 23,077,265 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Usp5
116 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:272
Count of miRNA genes:167
Interacting mature miRNAs:186
Transcripts:ENSRNOT00000020785
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
AI411387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,619,843 - 157,620,056 (-)MAPPERmRatBN7.2
mRatBN7.24157,619,843 - 157,620,056 (+)MAPPERmRatBN7.2
Rnor_6.04157,332,936 - 157,333,148NCBIRnor6.0
Rnor_6.0920,212,509 - 20,212,721NCBIRnor6.0
Rnor_5.04224,350,532 - 224,350,744UniSTSRnor5.0
Rnor_5.0919,088,485 - 19,088,697UniSTSRnor5.0
RGSC_v3.44160,937,902 - 160,938,114UniSTSRGSC3.4
Celera4146,357,822 - 146,358,034UniSTS
RH 3.4 Map41005.8UniSTS
Cytogenetic Map4q42UniSTS
MARC_7181-7182:996687603:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,622,121 - 157,622,508 (-)MAPPERmRatBN7.2
mRatBN7.24157,622,121 - 157,622,508 (+)MAPPERmRatBN7.2
Rnor_6.0920,210,057 - 20,210,443NCBIRnor6.0
Rnor_6.04157,335,214 - 157,335,600NCBIRnor6.0
Rnor_5.0919,086,033 - 19,086,419UniSTSRnor5.0
Rnor_5.04224,352,810 - 224,353,196UniSTSRnor5.0
RGSC_v3.44160,940,180 - 160,940,566UniSTSRGSC3.4
Celera4146,360,100 - 146,360,486UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020785   ⟹   ENSRNOP00000020785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4159,305,938 - 159,320,956 (-)Ensembl
mRatBN7.2 Ensembl4157,619,648 - 157,634,711 (-)Ensembl
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109840   ⟹   ENSRNOP00000078694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)Ensembl
RefSeq Acc Id: NM_001106619   ⟹   NP_001100089
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,938 - 159,320,956 (-)NCBI
mRatBN7.24157,619,663 - 157,634,681 (-)NCBI
Rnor_6.04157,332,740 - 157,347,803 (-)NCBI
Rnor_5.04224,350,331 - 224,365,479 (-)NCBI
RGSC_v3.44160,937,706 - 160,952,769 (-)RGD
Celera4146,357,626 - 146,372,628 (-)RGD
Sequence:
RefSeq Acc Id: NM_001394369   ⟹   NP_001381298
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,938 - 159,320,956 (-)NCBI
mRatBN7.24157,619,663 - 157,634,681 (-)NCBI
RefSeq Acc Id: XM_063285907   ⟹   XP_063141977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,927 - 159,321,345 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100089 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381298 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141977 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM01922 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020785
  ENSRNOP00000020785.4
RefSeq Acc Id: NP_001100089   ⟸   NM_001106619
- Peptide Label: isoform 1
- UniProtKB: D3ZVQ0 (UniProtKB/TrEMBL),   A6ILL7 (UniProtKB/TrEMBL),   A0A8I5ZLA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020785   ⟸   ENSRNOT00000020785
Ensembl Acc Id: ENSRNOP00000078694   ⟸   ENSRNOT00000109840
RefSeq Acc Id: NP_001381298   ⟸   NM_001394369
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZLA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141977   ⟸   XM_063285907
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLA4 (UniProtKB/TrEMBL)
Protein Domains
UBA   UBP-type   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVQ0-F1-model_v2 AlphaFold D3ZVQ0 1-858 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693391
Promoter ID:EPDNEW_R3916
Type:initiation region
Name:Usp5_1
Description:ubiquitin specific peptidase 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,347,773 - 157,347,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308438 AgrOrtholog
BioCyc Gene G2FUF-43065 BioCyc
Ensembl Genes ENSRNOG00000015409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020785 ENTREZGENE
  ENSRNOT00000020785.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Pept_C19ubi-hydrolase_C_CS UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitinyl_hydrolase UniProtKB/TrEMBL
  UBP13_Znf-UBP_var UniProtKB/TrEMBL
  UBP5_UBA1 UniProtKB/TrEMBL
  UCH/PAN2 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report rno:297593 UniProtKB/TrEMBL
NCBI Gene 297593 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
Pfam UBA_7 UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
  zf-UBP_var UniProtKB/TrEMBL
PhenoGen Usp5 PhenoGen
PIRSF UBP UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
  UCH_2_1 UniProtKB/TrEMBL
  UCH_2_2 UniProtKB/TrEMBL
  UCH_2_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015409 RatGTEx
SMART UBA UniProtKB/TrEMBL
  ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt A0A8I5ZLA4 ENTREZGENE
  A6ILL7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVQ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Usp5  ubiquitin specific peptidase 5  LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like  Data merged from RGD:6489834 737654 PROVISIONAL
2016-04-13 Usp5  ubiquitin specific peptidase 5  Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)      Symbol and Name status set to approved 70820 APPROVED