Itgb1bp1 (integrin subunit beta 1 binding protein 1) - Rat Genome Database

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Gene: Itgb1bp1 (integrin subunit beta 1 binding protein 1) Rattus norvegicus
Analyze
Symbol: Itgb1bp1
Name: integrin subunit beta 1 binding protein 1
RGD ID: 1307810
Description: Predicted to enable GDP-dissociation inhibitor activity; integrin binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including regulation of cell migration; regulation of cell-substrate adhesion; and regulation of signal transduction. Predicted to be located in several cellular components, including cytosol; nucleus; and perinuclear region of cytoplasm. Predicted to be active in several cellular components, including cytoskeleton; lamellipodium; and ruffle. Orthologous to human ITGB1BP1 (integrin subunit beta 1 binding protein 1); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; LOC298914
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,549,994 - 46,564,735 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl646,549,999 - 46,564,398 (-)EnsemblGRCr8
mRatBN7.2640,820,693 - 40,836,074 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,821,339 - 40,836,037 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx641,143,504 - 41,157,832 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,458,196 - 41,472,523 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0640,891,459 - 40,905,787 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,348,927 - 43,363,633 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)Ensemblrn6Rnor6.0
Rnor_5.0660,216,633 - 60,231,381 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4641,830,110 - 41,844,514 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera640,108,431 - 40,122,817 (-)NCBICelera
RGSC_v3.1641,833,498 - 41,847,916 (-)NCBI
Cytogenetic Map6q16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase B activity  (ISO)
angiogenesis  (IEA)
biomineral tissue development  (IEA)
blood vessel diameter maintenance  (ISO)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (ISO)
cell adhesion  (IEA)
cell differentiation  (IEA)
cell migration  (IEA)
cell-matrix adhesion  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to vascular endothelial growth factor stimulus  (ISO)
DNA-templated transcription  (IEA)
integrin activation  (IEA,ISO)
integrin-mediated signaling pathway  (ISO)
myoblast migration  (IEA,ISO)
negative regulation of cell adhesion involved in substrate-bound cell migration  (IEA,ISO)
negative regulation of cell migration  (IEA)
negative regulation of cell migration involved in sprouting angiogenesis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of fibroblast migration  (IEA,ISO)
negative regulation of focal adhesion assembly  (IEA,ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein targeting to membrane  (ISO)
negative regulation of substrate adhesion-dependent cell spreading  (IEA,ISO)
Notch signaling pathway  (IEA)
positive regulation of cell division  (IEA)
positive regulation of cell population proliferation  (ISO)
positive regulation of endothelial cell migration  (ISO)
positive regulation of focal adhesion assembly  (IEA,ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of protein targeting to membrane  (IEA,ISO)
positive regulation of stress fiber assembly  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
protein localization to membrane  (IEA)
protein localization to plasma membrane  (ISO)
receptor clustering  (IEA,ISO)
regulation of cell adhesion mediated by integrin  (IEA,ISO)
regulation of integrin-mediated signaling pathway  (IEA,ISO)
regulation of protein targeting to membrane  (IEA)
regulation of signal transduction  (IEA)
tube formation  (ISO)

Cellular Component
cell periphery  (IEA,ISO)
cytoplasm  (ISO)
cytoskeleton  (IEA,ISO)
cytosol  (ISO)
focal adhesion  (ISO)
lamellipodium  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IEA,ISO)
perinuclear region of cytoplasm  (ISO)
plasma membrane  (IEA,ISO)
ruffle  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Integrin inactivators: balancing cellular functions in vitro and in vivo. Bouvard D, etal., Nat Rev Mol Cell Biol. 2013 Jul;14(7):430-42. doi: 10.1038/nrm3599. Epub 2013 May 30.
2. Talins and kindlins: partners in integrin-mediated adhesion. Calderwood DA, etal., Nat Rev Mol Cell Biol. 2013 Aug;14(8):503-17. doi: 10.1038/nrm3624. Epub 2013 Jul 17.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9281591   PMID:11807099   PMID:11919189   PMID:12473654   PMID:12477932   PMID:15703214   PMID:16741948   PMID:17654484   PMID:17916086   PMID:18227284   PMID:20616313   PMID:23376485  


Genomics

Comparative Map Data
Itgb1bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,549,994 - 46,564,735 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl646,549,999 - 46,564,398 (-)EnsemblGRCr8
mRatBN7.2640,820,693 - 40,836,074 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,821,339 - 40,836,037 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx641,143,504 - 41,157,832 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,458,196 - 41,472,523 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0640,891,459 - 40,905,787 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,348,927 - 43,363,633 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)Ensemblrn6Rnor6.0
Rnor_5.0660,216,633 - 60,231,381 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4641,830,110 - 41,844,514 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera640,108,431 - 40,122,817 (-)NCBICelera
RGSC_v3.1641,833,498 - 41,847,916 (-)NCBI
Cytogenetic Map6q16NCBI
ITGB1BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,403,475 - 9,423,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl29,403,475 - 9,423,891 (-)Ensemblhg38GRCh38
GRCh3729,543,604 - 9,563,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,463,264 - 9,481,094 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3429,496,414 - 9,514,233NCBI
Celera29,457,992 - 9,475,539 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,391,245 - 9,409,126 (-)NCBIHuRef
CHM1_129,475,472 - 9,493,078 (-)NCBICHM1_1
T2T-CHM13v2.029,428,778 - 9,448,648 (-)NCBIT2T-CHM13v2.0
Itgb1bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,317,247 - 21,336,285 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,290,826 - 21,336,285 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381221,267,246 - 21,286,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1221,240,825 - 21,286,284 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl1221,267,420 - 21,286,284 (-)Ensemblmm10GRCm38
MGSCv371221,275,667 - 21,292,098 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361221,516,296 - 21,532,727 (-)NCBIMGSCv36mm8
Celera1219,618,971 - 19,635,133 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.3NCBI
Itgb1bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,134,135 - 5,146,449 (-)Ensembl
ChiLan1.0NW_0049554875,134,135 - 5,146,449 (-)NCBIChiLan1.0ChiLan1.0
ITGB1BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212117,103,099 - 117,119,941 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A117,107,072 - 117,123,914 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,396,553 - 9,413,408 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A9,559,416 - 9,576,899 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A9,556,857 - 9,577,155 (-)EnsemblpanPan2panpan1.1
ITGB1BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,524,602 - 6,537,321 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,524,613 - 6,537,233 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha176,452,429 - 6,465,110 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0176,623,442 - 6,636,129 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,623,416 - 6,636,121 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,515,976 - 6,528,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,518,396 - 6,531,054 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,531,756 - 6,544,438 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Itgb1bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,047,715 - 51,059,189 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365325,799,342 - 5,814,199 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365325,802,761 - 5,814,226 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB1BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,905,810 - 126,922,045 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13126,905,779 - 126,921,961 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,174,258 - 135,295,240 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB1BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,226,666 - 98,244,094 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1498,230,100 - 98,248,862 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604514,079,143 - 14,096,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itgb1bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969290,570 - 301,189 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624969290,601 - 307,152 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Itgb1bp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1737,812,762 - 37,827,192 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Itgb1bp1
37 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:58
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000009401
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)64005241156848866Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat

Markers in Region
D6Got50  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,832,154 - 40,832,315 (+)MAPPERmRatBN7.2
Rnor_6.0643,359,743 - 43,359,903NCBIRnor6.0
Rnor_5.0660,227,449 - 60,227,609UniSTSRnor5.0
RGSC_v3.4641,840,921 - 41,841,082RGDRGSC3.4
RGSC_v3.4641,840,922 - 41,841,082UniSTSRGSC3.4
Celera640,119,243 - 40,119,385UniSTS
RGSC_v3.1641,844,048 - 41,844,208RGD
RH 3.4 Map6223.4UniSTS
RH 3.4 Map6223.4RGD
RH 2.0 Map6375.1RGD
Cytogenetic Map6q16UniSTS
RH143075  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,825,459 - 40,825,759 (+)MAPPERmRatBN7.2
Rnor_6.0643,353,049 - 43,353,348NCBIRnor6.0
Rnor_5.0660,220,755 - 60,221,054UniSTSRnor5.0
RGSC_v3.4641,834,228 - 41,834,527UniSTSRGSC3.4
Celera640,112,549 - 40,112,848UniSTS
RH 3.4 Map6223.5UniSTS
Cytogenetic Map6q16UniSTS
AI449260  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,822,278 - 40,822,362 (+)MAPPERmRatBN7.2
Rnor_6.0643,349,868 - 43,349,951NCBIRnor6.0
Rnor_5.0660,217,574 - 60,217,657UniSTSRnor5.0
RGSC_v3.4641,831,047 - 41,831,130UniSTSRGSC3.4
Celera640,109,368 - 40,109,451UniSTS
Cytogenetic Map6q16UniSTS
RH141519  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8646,550,024 - 46,550,235 (+)Marker Load Pipeline
mRatBN7.2640,821,372 - 40,821,583 (+)MAPPERmRatBN7.2
Rnor_6.0643,348,962 - 43,349,172NCBIRnor6.0
Rnor_5.0660,216,668 - 60,216,878UniSTSRnor5.0
RGSC_v3.4641,830,141 - 41,830,351UniSTSRGSC3.4
Celera640,108,462 - 40,108,672UniSTS
Cytogenetic Map6q16UniSTS
BG372800  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,825,142 - 40,825,276 (+)MAPPERmRatBN7.2
Rnor_6.0643,352,732 - 43,352,865NCBIRnor6.0
Rnor_5.0660,220,438 - 60,220,571UniSTSRnor5.0
RGSC_v3.4641,833,911 - 41,834,044UniSTSRGSC3.4
Celera640,112,232 - 40,112,365UniSTS
RH 3.4 Map6221.0UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC169104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000092192   ⟹   ENSRNOP00000071708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl646,549,999 - 46,564,398 (-)Ensembl
mRatBN7.2 Ensembl640,821,342 - 40,836,037 (-)Ensembl
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103709   ⟹   ENSRNOP00000095877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,821,626 - 40,836,012 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116410   ⟹   ENSRNOP00000086750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,821,339 - 40,825,790 (-)Ensembl
RefSeq Acc Id: NM_001106719   ⟹   NP_001100189
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,398 (-)NCBI
mRatBN7.2640,821,342 - 40,835,747 (-)NCBI
Rnor_6.0643,348,931 - 43,363,335 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
RGSC_v3.4641,830,110 - 41,844,514 (-)RGD
Celera640,108,431 - 40,122,817 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239979   ⟹   XP_006240041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,700 (-)NCBI
mRatBN7.2640,821,338 - 40,836,073 (-)NCBI
Rnor_6.0643,348,927 - 43,363,633 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239980   ⟹   XP_006240042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,735 (-)NCBI
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
Rnor_6.0643,348,927 - 43,363,633 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239981   ⟹   XP_006240043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,567 (-)NCBI
mRatBN7.2640,821,338 - 40,835,894 (-)NCBI
Rnor_6.0643,348,927 - 43,363,491 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111951   ⟹   XP_038967879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,713 (-)NCBI
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
RefSeq Acc Id: XM_039111952   ⟹   XP_038967880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,542 (-)NCBI
mRatBN7.2640,821,338 - 40,835,894 (-)NCBI
RefSeq Acc Id: XM_039111953   ⟹   XP_038967881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,713 (-)NCBI
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
RefSeq Acc Id: XM_063261656   ⟹   XP_063117726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,549,994 - 46,564,542 (-)NCBI
RefSeq Acc Id: NP_001100189   ⟸   NM_001106719
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL),   A6HAV6 (UniProtKB/TrEMBL),   A0A0G2K157 (UniProtKB/TrEMBL),   A0A8I6GLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240041   ⟸   XM_006239979
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240042   ⟸   XM_006239980
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240043   ⟸   XM_006239981
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071708   ⟸   ENSRNOT00000092192
RefSeq Acc Id: XP_038967881   ⟸   XM_039111953
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967879   ⟸   XM_039111951
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967880   ⟸   XM_039111952
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL),   A6HAV6 (UniProtKB/TrEMBL),   A0A0G2K157 (UniProtKB/TrEMBL),   A0A8I6GLU4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095877   ⟸   ENSRNOT00000103709
Ensembl Acc Id: ENSRNOP00000086750   ⟸   ENSRNOT00000116410
RefSeq Acc Id: XP_063117726   ⟸   XM_063261656
- Peptide Label: isoform X1
Protein Domains
PID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DFL3-F1-model_v2 AlphaFold B5DFL3 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694515
Promoter ID:EPDNEW_R5037
Type:single initiation site
Name:Itgb1bp1_1
Description:integrin subunit beta 1 binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0643,363,324 - 43,363,384EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307810 AgrOrtholog
BioCyc Gene G2FUF-38041 BioCyc
Ensembl Genes ENSRNOG00000059402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092192 ENTREZGENE
  ENSRNOT00000092192.3 UniProtKB/TrEMBL
Gene3D-CATH 6.20.360.10 UniProtKB/TrEMBL
InterPro Integrin_bd_ICAP-1 UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
KEGG Report rno:298914 UniProtKB/TrEMBL
NCBI Gene 298914 ENTREZGENE
PANTHER INTEGRIN BETA-1-BINDING PROTEIN 1 UniProtKB/TrEMBL
  PTHR32055 UniProtKB/TrEMBL
Pfam ICAP-1_inte_bdg UniProtKB/TrEMBL
PhenoGen Itgb1bp1 PhenoGen
RatGTEx ENSRNOG00000059402 RatGTEx
SMART PTB UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A0G2K157 ENTREZGENE
  A0A8I6GLU4 ENTREZGENE, UniProtKB/TrEMBL
  A6HAV6 ENTREZGENE, UniProtKB/TrEMBL
  B5DFL3 ENTREZGENE
UniProt Secondary A0A0G2K157 UniProtKB/TrEMBL
  B5DFL3 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Itgb1bp1  integrin subunit beta 1 binding protein 1  Itgb1bp1  integrin beta 1 binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Itgb1bp1  integrin beta 1 binding protein 1   Itgb1bp1_predicted  integrin beta 1 binding protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Itgb1bp1_predicted  integrin beta 1 binding protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED