Wdr6 (WD repeat domain 6) - Rat Genome Database

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Gene: Wdr6 (WD repeat domain 6) Rattus norvegicus
Analyze
Symbol: Wdr6
Name: WD repeat domain 6
RGD ID: 1307649
Description: Enables insulin receptor substrate binding activity. Predicted to be involved in negative regulation of autophagy; negative regulation of cell population proliferation; and wobble position ribose methylation. Predicted to act upstream of with a negative effect on G1 to G0 transition. Part of protein-containing complex. Orthologous to human WDR6 (WD repeat domain 6); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC301007; MGC105944; tRNA (34-2'-O)-methyltransferase regulator WDR6; WD repeat domain 6 protein; WD repeat-containing protein 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,146,608 - 118,153,024 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,146,608 - 118,153,092 (-)EnsemblGRCr8
mRatBN7.28109,268,079 - 109,274,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,268,079 - 109,274,499 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,886,331 - 114,892,761 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,085,665 - 113,092,095 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,928,305 - 110,934,735 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,358,345 - 117,364,761 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,358,787 - 117,366,096 (-)Ensemblrn6Rnor6.0
Rnor_5.08116,702,848 - 116,709,264 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,618,341 - 113,624,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,563,853 - 108,570,269 (-)NCBICelera
RGSC_v3.18113,637,801 - 113,638,950 (-)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Dwarfism  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromuconazole  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
ivermectin  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
miconazole  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nitrates  (ISO)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
COP9 signalosome  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
protein-containing complex  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: Implications for longevity. Chiba T, etal., Neurobiol Aging. 2007 Aug 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15632090   PMID:17216128   PMID:18850735   PMID:22354037   PMID:22658674  


Genomics

Comparative Map Data
Wdr6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,146,608 - 118,153,024 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,146,608 - 118,153,092 (-)EnsemblGRCr8
mRatBN7.28109,268,079 - 109,274,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,268,079 - 109,274,499 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,886,331 - 114,892,761 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,085,665 - 113,092,095 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,928,305 - 110,934,735 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,358,345 - 117,364,761 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,358,787 - 117,366,096 (-)Ensemblrn6Rnor6.0
Rnor_5.08116,702,848 - 116,709,264 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,618,341 - 113,624,757 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,563,853 - 108,570,269 (-)NCBICelera
RGSC_v3.18113,637,801 - 113,638,950 (-)NCBI
Cytogenetic Map8q32NCBI
WDR6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,007,391 - 49,015,951 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl349,007,062 - 49,015,953 (+)Ensemblhg38GRCh38
GRCh37349,044,824 - 49,053,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,019,830 - 49,028,390 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34349,019,829 - 49,028,386NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,102,440 - 49,111,251 (+)NCBIHuRef
CHM1_1348,997,191 - 49,005,947 (+)NCBICHM1_1
T2T-CHM13v2.0349,035,431 - 49,043,991 (+)NCBIT2T-CHM13v2.0
Wdr6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,449,510 - 108,455,862 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,449,510 - 108,455,938 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm389108,572,311 - 108,578,713 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,572,311 - 108,578,739 (-)Ensemblmm10GRCm38
MGSCv379108,474,644 - 108,481,001 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369108,430,416 - 108,436,869 (-)NCBIMGSCv36mm8
Celera9108,183,554 - 108,189,907 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.51NCBI
Wdr6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,028,466 - 1,039,020 (+)Ensembl
ChiLan1.0NW_0049555321,029,857 - 1,039,020 (+)NCBIChiLan1.0ChiLan1.0
WDR6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,986,031 - 48,994,763 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,990,824 - 48,999,529 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,931,669 - 48,940,591 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1350,013,570 - 50,022,034 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,013,708 - 50,021,367 (+)EnsemblpanPan2panpan1.1
WDR6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,148,262 - 40,157,770 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,148,928 - 40,157,650 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2040,066,440 - 40,075,980 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02040,505,441 - 40,515,223 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,505,441 - 40,515,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,872,036 - 39,881,691 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,275,813 - 40,285,364 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,555,322 - 40,564,865 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdr6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,971,461 - 63,980,835 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529730,716 - 745,427 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936529731,958 - 741,334 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,642,325 - 31,651,361 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11331,642,207 - 31,651,367 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,885,702 - 34,894,484 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,407,421 - 10,416,295 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,407,703 - 10,415,633 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041156,665,972 - 156,675,272 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,055,610 - 3,063,153 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247303,058,947 - 3,063,709 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Wdr6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1899,901,942 - 99,908,459 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wdr6
54 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:324
Count of miRNA genes:202
Interacting mature miRNAs:236
Transcripts:ENSRNOT00000027411
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH128647  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,274,659 - 109,274,840 (+)MAPPERmRatBN7.2
Rnor_6.08117,364,926 - 117,365,106NCBIRnor6.0
Rnor_5.08116,709,429 - 116,709,609UniSTSRnor5.0
RGSC_v3.48113,624,922 - 113,625,102UniSTSRGSC3.4
Celera8108,570,434 - 108,570,614UniSTS
RH 3.4 Map81117.6UniSTS
Cytogenetic Map8q32UniSTS
BB128974  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,274,626 - 109,274,710 (+)MAPPERmRatBN7.2
Rnor_6.08117,364,893 - 117,364,976NCBIRnor6.0
Rnor_5.08116,709,396 - 116,709,479UniSTSRnor5.0
RGSC_v3.48113,624,889 - 113,624,972UniSTSRGSC3.4
Celera8108,570,401 - 108,570,484UniSTS
Cytogenetic Map8q32UniSTS
AI853847  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,274,645 - 109,274,766 (+)MAPPERmRatBN7.2
Rnor_6.08117,364,912 - 117,365,032NCBIRnor6.0
Rnor_5.08116,709,415 - 116,709,535UniSTSRnor5.0
RGSC_v3.48113,624,908 - 113,625,028UniSTSRGSC3.4
Celera8108,570,420 - 108,570,540UniSTS
Cytogenetic Map8q32UniSTS
RH137218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,268,123 - 109,268,306 (+)MAPPERmRatBN7.2
Rnor_6.08117,358,390 - 117,358,572NCBIRnor6.0
Rnor_5.08116,702,893 - 116,703,075UniSTSRnor5.0
RGSC_v3.48113,618,386 - 113,618,568UniSTSRGSC3.4
Celera8108,563,898 - 108,564,080UniSTS
RH 3.4 Map81117.6UniSTS
Cytogenetic Map8q32UniSTS
AW530353  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,271,649 - 109,271,814 (+)MAPPERmRatBN7.2
Rnor_6.08117,361,916 - 117,362,080NCBIRnor6.0
Rnor_5.08116,706,419 - 116,706,583UniSTSRnor5.0
RGSC_v3.48113,621,912 - 113,622,076UniSTSRGSC3.4
Celera8108,567,424 - 108,567,588UniSTS
RH 3.4 Map81116.7UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027411   ⟹   ENSRNOP00000027411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,146,608 - 118,153,092 (-)Ensembl
mRatBN7.2 Ensembl8109,268,079 - 109,274,499 (-)Ensembl
Rnor_6.0 Ensembl8117,358,787 - 117,366,096 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112677   ⟹   ENSRNOP00000097790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,146,608 - 118,153,024 (-)Ensembl
mRatBN7.2 Ensembl8109,268,079 - 109,274,499 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000162223   ⟹   ENSRNOP00000106773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,146,608 - 118,152,485 (-)Ensembl
RefSeq Acc Id: NM_001006988   ⟹   NP_001006989
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,146,608 - 118,153,024 (-)NCBI
mRatBN7.28109,268,079 - 109,274,495 (-)NCBI
Rnor_6.08117,358,345 - 117,364,761 (-)NCBI
Rnor_5.08116,702,848 - 116,709,264 (-)NCBI
RGSC_v3.48113,618,341 - 113,624,757 (-)RGD
Celera8108,563,853 - 108,570,269 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001006989 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH84708 (Get FASTA)   NCBI Sequence Viewer  
  EDL77156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027411
  ENSRNOP00000027411.5
GenBank Protein Q5XFW6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001006989   ⟸   NM_001006988
- UniProtKB: Q5XFW6 (UniProtKB/Swiss-Prot),   A0A8I6AWT4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027411   ⟸   ENSRNOT00000027411
Ensembl Acc Id: ENSRNOP00000097790   ⟸   ENSRNOT00000112677
Ensembl Acc Id: ENSRNOP00000106773   ⟸   ENSRNOT00000162223

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XFW6-F1-model_v2 AlphaFold Q5XFW6 1-1125 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696312
Promoter ID:EPDNEW_R6836
Type:initiation region
Name:Wdr6_1
Description:WD repeat domain 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,364,626 - 117,364,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307649 AgrOrtholog
BioCyc Gene G2FUF-29124 BioCyc
Ensembl Genes ENSRNOG00000020185 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027411 ENTREZGENE
  ENSRNOT00000027411.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7301769 IMAGE-MGC_LOAD
InterPro Quinoprotein_ADH-like_supfam UniProtKB/Swiss-Prot
  tRNA_Anticodon_Mtase-Reg UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:301007 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105944 IMAGE-MGC_LOAD
NCBI Gene 301007 ENTREZGENE
PANTHER WD REPEAT PROTEIN UniProtKB/Swiss-Prot
  WD REPEAT-CONTAINING PROTEIN 6 UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Wdr6 PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020185 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
  SSF50998 UniProtKB/Swiss-Prot
UniProt A0A8I6AWT4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LPI6_RAT UniProtKB/TrEMBL
  Q5XFW6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Wdr6  WD repeat domain 6  Wdr6_predicted  WD repeat domain 6 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdr6_predicted  WD repeat domain 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED