Ripor2 (RHO family interacting cell polarization regulator 2) - Rat Genome Database

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Gene: Ripor2 (RHO family interacting cell polarization regulator 2) Rattus norvegicus
Analyze
Symbol: Ripor2
Name: RHO family interacting cell polarization regulator 2
RGD ID: 1306939
Description: Predicted to enable 14-3-3 protein binding activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of T cell activation; positive regulation of cellular component organization; and regulation of leukocyte migration. Located in apical plasma membrane and stereocilium membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 21 and autosomal recessive nonsyndromic deafness 104. Orthologous to human RIPOR2 (RHO family interacting cell polarization regulator 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ab2-162; Fam65b; family with sequence similarity 65, member B; hypothetical protein LOC306934; LOC306934; RGD1306939; rho family-interacting cell polarization regulator 2; similar to mKIAA0386 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,751,771 - 40,975,611 (-)NCBIGRCr8
mRatBN7.21740,323,748 - 40,547,482 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,323,867 - 40,548,092 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,391,656 - 40,489,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,995,696 - 42,093,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,278,937 - 40,376,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,324,594 - 42,549,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,324,594 - 42,422,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,192,188 - 44,415,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,394,370 - 47,492,203 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11747,404,460 - 47,517,088 (-)NCBI
Celera1739,960,748 - 40,058,550 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (EXP)
amitrole  (EXP)
amphotericin B  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
cobalt dichloride  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dimethylarsinic acid  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
isobutanol  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
pyrethrins  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
apical plasma membrane  (IDA,IEA)
cytoplasm  (IEA,ISO,ISS)
cytoskeleton  (IEA,ISO,ISS)
filopodium  (IEA,ISO,ISS)
stereocilium  (IDA,ISO)
stereocilium membrane  (IDA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing. Diaz-Horta O, etal., Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9864-8. doi: 10.1073/pnas.1401950111. Epub 2014 Jun 23.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17150207   PMID:23241886   PMID:24687993   PMID:25588844   PMID:27269051   PMID:27556504  


Genomics

Comparative Map Data
Ripor2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,751,771 - 40,975,611 (-)NCBIGRCr8
mRatBN7.21740,323,748 - 40,547,482 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,323,867 - 40,548,092 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,391,656 - 40,489,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,995,696 - 42,093,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,278,937 - 40,376,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,324,594 - 42,549,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,324,594 - 42,422,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,192,188 - 44,415,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,394,370 - 47,492,203 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11747,404,460 - 47,517,088 (-)NCBI
Celera1739,960,748 - 40,058,550 (-)NCBICelera
Cytogenetic Map17p11NCBI
RIPOR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,804,284 - 25,042,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,804,282 - 25,042,170 (-)EnsemblGRCh38hg38GRCh38
GRCh37624,804,512 - 25,042,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,947,566 - 24,985,562 (-)NCBINCBI36Build 36hg18NCBI36
Build 34624,947,575 - 24,985,562NCBI
Celera626,037,884 - 26,138,491 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,753,953 - 24,854,449 (-)NCBIHuRef
CHM1_1624,808,618 - 24,913,299 (-)NCBICHM1_1
T2T-CHM13v2.0624,675,432 - 24,907,349 (-)NCBIT2T-CHM13v2.0
Ripor2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391324,685,513 - 24,917,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1324,685,508 - 24,917,799 (+)EnsemblGRCm39 Ensembl
GRCm381324,501,524 - 24,733,806 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,501,525 - 24,733,816 (+)EnsemblGRCm38mm10GRCm38
MGSCv371324,706,479 - 24,825,675 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,676,030 - 24,713,412 (+)NCBIMGSCv36mm8
Celera1324,845,270 - 24,964,462 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.5NCBI
Ripor2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,048,324 - 2,256,589 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,048,236 - 2,257,078 (+)NCBIChiLan1.0ChiLan1.0
RIPOR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,455,658 - 39,581,492 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,455,205 - 35,581,073 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,642,239 - 24,768,074 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,973,412 - 25,099,034 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,973,412 - 25,204,745 (-)Ensemblpanpan1.1panPan2
RIPOR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,823,053 - 23,041,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,824,106 - 23,041,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,790,986 - 23,009,662 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,945,432 - 23,164,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,945,030 - 23,164,199 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,750,468 - 22,968,713 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,799,010 - 23,016,747 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03524,234,583 - 24,454,231 (-)NCBIUU_Cfam_GSD_1.0
Ripor2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049462,388,691 - 2,556,595 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366711,051,742 - 1,093,021 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366711,064,937 - 1,232,985 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIPOR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,609,358 - 19,838,093 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,609,358 - 19,842,345 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,762,727 - 20,990,748 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIPOR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,197,067 - 47,441,413 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,308,984 - 47,451,779 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,739,532 - 24,983,846 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ripor2
1236 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:56
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000048298
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 16 10 19 60 8 11
Low 1 27 41 35 35 8 11 12 35 32 8
Below cutoff 6 6 6 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY325194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000048298   ⟹   ENSRNOP00000048390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,323,867 - 40,421,722 (-)Ensembl
Rnor_6.0 Ensembl1742,324,594 - 42,422,053 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097819   ⟹   ENSRNOP00000094332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,364,701 - 40,419,234 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101796   ⟹   ENSRNOP00000096913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,355,070 - 40,419,234 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102510   ⟹   ENSRNOP00000096012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,355,070 - 40,548,092 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107097   ⟹   ENSRNOP00000096131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,329,495 - 40,418,575 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110402   ⟹   ENSRNOP00000082516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,329,495 - 40,419,234 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117790   ⟹   ENSRNOP00000083444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,355,070 - 40,444,144 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117811   ⟹   ENSRNOP00000077001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,329,495 - 40,419,234 (-)Ensembl
RefSeq Acc Id: NM_001014009   ⟹   NP_001014031
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,751,771 - 40,849,714 (-)NCBI
mRatBN7.21740,323,748 - 40,421,722 (-)NCBI
Rnor_6.01742,324,594 - 42,422,053 (-)NCBI
Rnor_5.01744,192,188 - 44,415,275 (-)NCBI
RGSC_v3.41747,394,370 - 47,492,203 (-)RGD
Celera1739,960,748 - 40,058,550 (-)RGD
Sequence:
RefSeq Acc Id: XM_006253929   ⟹   XP_006253991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,871,818 (-)NCBI
mRatBN7.21740,329,494 - 40,443,820 (-)NCBI
Rnor_6.01742,330,223 - 42,444,317 (-)NCBI
Rnor_5.01744,192,188 - 44,415,275 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253930   ⟹   XP_006253992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,847,309 (-)NCBI
mRatBN7.21740,329,494 - 40,419,317 (-)NCBI
Rnor_6.01742,330,223 - 42,419,374 (-)NCBI
Rnor_5.01744,192,188 - 44,415,275 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600530   ⟹   XP_017456019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,975,611 (-)NCBI
mRatBN7.21740,329,494 - 40,547,480 (-)NCBI
Rnor_6.01742,330,223 - 42,549,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600531   ⟹   XP_017456020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,975,583 (-)NCBI
mRatBN7.21740,329,494 - 40,547,482 (-)NCBI
Rnor_6.01742,330,223 - 42,549,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600533   ⟹   XP_017456022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,975,611 (-)NCBI
mRatBN7.21740,329,494 - 40,547,476 (-)NCBI
Rnor_6.01742,330,223 - 42,549,905 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600534   ⟹   XP_017456023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,783,089 - 40,975,611 (-)NCBI
mRatBN7.21740,355,064 - 40,547,482 (-)NCBI
Rnor_6.01742,355,424 - 42,549,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600535   ⟹   XP_017456024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,783,089 - 40,975,611 (-)NCBI
mRatBN7.21740,355,064 - 40,547,475 (-)NCBI
Rnor_6.01742,355,424 - 42,549,904 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063276411   ⟹   XP_063132481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,846,710 (-)NCBI
RefSeq Acc Id: XM_063276412   ⟹   XP_063132482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,871,966 (-)NCBI
RefSeq Acc Id: XM_063276413   ⟹   XP_063132483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,847,309 (-)NCBI
RefSeq Acc Id: XM_063276414   ⟹   XP_063132484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,757,519 - 40,847,051 (-)NCBI
RefSeq Acc Id: XM_063276415   ⟹   XP_063132485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,783,089 - 40,847,309 (-)NCBI
RefSeq Acc Id: XM_063276416   ⟹   XP_063132486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,783,089 - 40,871,818 (-)NCBI
RefSeq Acc Id: XM_063276417   ⟹   XP_063132487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,783,089 - 40,847,309 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001014031 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253991 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253992 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456019 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456020 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456022 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456023 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456024 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132481 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132482 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132483 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132484 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132485 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132486 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132487 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP92595 (Get FASTA)   NCBI Sequence Viewer  
  EDL86507 (Get FASTA)   NCBI Sequence Viewer  
  EDL86508 (Get FASTA)   NCBI Sequence Viewer  
  EDL86509 (Get FASTA)   NCBI Sequence Viewer  
  EDL86510 (Get FASTA)   NCBI Sequence Viewer  
  EDL86511 (Get FASTA)   NCBI Sequence Viewer  
  EDL86512 (Get FASTA)   NCBI Sequence Viewer  
  EDL86513 (Get FASTA)   NCBI Sequence Viewer  
  EDL86514 (Get FASTA)   NCBI Sequence Viewer  
  EDL86515 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048390
  ENSRNOP00000048390.1
  ENSRNOP00000077001.1
  ENSRNOP00000082516
  ENSRNOP00000082516.1
  ENSRNOP00000083444.1
  ENSRNOP00000094332.1
  ENSRNOP00000096012
  ENSRNOP00000096012.1
  ENSRNOP00000096131.1
  ENSRNOP00000096913
  ENSRNOP00000096913.1
GenBank Protein Q7TP54 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001014031   ⟸   NM_001014009
- UniProtKB: Q7TP54 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006253991   ⟸   XM_006253929
- Peptide Label: isoform X3
- UniProtKB: A6KLG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253992   ⟸   XM_006253930
- Peptide Label: isoform X4
- UniProtKB: A0A8I5Y5T3 (UniProtKB/TrEMBL),   A6KLG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456020   ⟸   XM_017600531
- Peptide Label: isoform X2
- UniProtKB: A6KLG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456019   ⟸   XM_017600530
- Peptide Label: isoform X1
- UniProtKB: A6KLG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456022   ⟸   XM_017600533
- Peptide Label: isoform X6
- UniProtKB: A6KLG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456023   ⟸   XM_017600534
- Peptide Label: isoform X10
- UniProtKB: A0A8I6AQC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456024   ⟸   XM_017600535
- Peptide Label: isoform X12
- UniProtKB: A0A8I6AP27 (UniProtKB/TrEMBL),   A0A8I5ZX07 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000048390   ⟸   ENSRNOT00000048298
RefSeq Acc Id: ENSRNOP00000082516   ⟸   ENSRNOT00000110402
RefSeq Acc Id: ENSRNOP00000077001   ⟸   ENSRNOT00000117811
RefSeq Acc Id: ENSRNOP00000083444   ⟸   ENSRNOT00000117790
RefSeq Acc Id: ENSRNOP00000096913   ⟸   ENSRNOT00000101796
RefSeq Acc Id: ENSRNOP00000096131   ⟸   ENSRNOT00000107097
RefSeq Acc Id: ENSRNOP00000094332   ⟸   ENSRNOT00000097819
RefSeq Acc Id: ENSRNOP00000096012   ⟸   ENSRNOT00000102510
RefSeq Acc Id: XP_063132482   ⟸   XM_063276412
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132483   ⟸   XM_063276413
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132484   ⟸   XM_063276414
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063132481   ⟸   XM_063276411
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063132486   ⟸   XM_063276416
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063132487   ⟸   XM_063276417
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063132485   ⟸   XM_063276415
- Peptide Label: isoform X11
Protein Domains
FAM65 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TP54-F1-model_v2 AlphaFold Q7TP54 1-1310 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306939 AgrOrtholog
BioCyc Gene G2FUF-9416 BioCyc
Ensembl Genes ENSRNOG00000018804 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048298 ENTREZGENE
  ENSRNOT00000048298.2 UniProtKB/Swiss-Prot
  ENSRNOT00000097819.1 UniProtKB/TrEMBL
  ENSRNOT00000101796.1 UniProtKB/TrEMBL
  ENSRNOT00000102510.1 UniProtKB/TrEMBL
  ENSRNOT00000107097.1 UniProtKB/TrEMBL
  ENSRNOT00000110402 ENTREZGENE
  ENSRNOT00000110402.1 UniProtKB/TrEMBL
  ENSRNOT00000117790.1 UniProtKB/TrEMBL
  ENSRNOT00000117811.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1260.10 UniProtKB/Swiss-Prot
  1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAM65_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferritin-like UniProtKB/Swiss-Prot
  Ferritin-like_diiron UniProtKB/Swiss-Prot
  Ferritin-like_SF UniProtKB/Swiss-Prot
  Ferritin_CS UniProtKB/Swiss-Prot
  Ferritin_DPS_dom UniProtKB/Swiss-Prot
  RIPOR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:306934 UniProtKB/Swiss-Prot
NCBI Gene 306934 ENTREZGENE
PANTHER PTHR15829 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15829:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ferritin UniProtKB/Swiss-Prot
  PL48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ripor2 PhenoGen
PROSITE FERRITIN_2 UniProtKB/Swiss-Prot
  FERRITIN_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018804 RatGTEx
Superfamily-SCOP SSF47240 UniProtKB/Swiss-Prot
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y5T3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZX07 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALX2_RAT UniProtKB/TrEMBL
  A0A8I6AP27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLY0_RAT UniProtKB/TrEMBL
  A6KLG3 ENTREZGENE, UniProtKB/TrEMBL
  A6KLG4 ENTREZGENE, UniProtKB/TrEMBL
  Q7TP54 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-07 Ripor2  RHO family interacting cell polarization regulator 2  Fam65b  family with sequence similarity 65, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Fam65b  family with sequence similarity 65, member B  RGD1306939  similar to mKIAA0386 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1306939  similar to mKIAA0386 protein  RGD1306939_predicted  similar to mKIAA0386 protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306939_predicted  similar to mKIAA0386 protein (predicted)  LOC306934_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC306934_predicted  similar to mKIAA0386 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL