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Gene: Atp13a5 (ATPase 13A5) Rattus norvegicus

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Symbol:

Atp13a5

Name:

ATPase 13A5

RGD ID:

1306792

Description:

Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity and polyamine transmembrane transporter activity. Predicted to be involved in intracellular calcium ion homeostasis and polyamine transmembrane transport. Predicted to be located in membrane. Predicted to be active in late endosome membrane. Orthologous to human ATP13A5 (ATPase 13A5); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ATPase type 13A5; LOC303856; probable cation-transporting ATPase 13A5; RGD1306792; similar to putative ATPase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATP13A5 (ATPase 13A5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Atp13a5 (ATPase type 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Atp13a5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ATP13A5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATP13A5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Atp13a5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ATP13A5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATP13A5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Atp13a5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Atp13a5 (ATPase 13A5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TRIM56 (tripartite motif containing 56)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ATP13A5 (ATPase 13A5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atp13a5 (ATPase type 13A5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YPK9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YPK9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	anne	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	anne	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	catp-6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	catp-6	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	atp13a5	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	atp13a5	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	84,881,196 - 85,020,597 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	84,881,230 - 85,020,593 (+)	Ensembl				GRCr8
mRatBN7.2	11	71,376,388 - 71,515,789 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	71,376,422 - 71,515,789 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	80,221,615 - 80,361,226 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	72,856,573 - 72,996,189 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	71,911,008 - 72,050,519 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	74,984,538 - 75,124,249 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	74,984,613 - 75,124,249 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	78,029,982 - 78,168,702 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	73,267,689 - 73,418,786 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	70,339,871 - 70,477,936 (+)	NCBI		Celera
RGSC_v3.1	11	73,325,397 - 73,475,692 (+)	NCBI
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

folic acid (ISO)

geldanamycin (ISO)

leflunomide (ISO)

mercury dichloride (ISO)

nickel atom (ISO)

ozone (ISO)

perfluorooctanoic acid (EXP)

riddelliine (EXP)

sodium arsenite (ISO)

Soman (EXP)

testosterone (EXP)

toluene (EXP)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular calcium ion homeostasis (IBA)

monoatomic cation transmembrane transport (IEA)

monoatomic ion transmembrane transport (IEA)

polyamine transmembrane transport (IBA)

Cellular Component

late endosome membrane (IBA)

membrane (IEA)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATPase-coupled monoatomic cation transmembrane transporter activity (IBA,IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

P-type ion transporter activity (IEA)

P-type transmembrane transporter activity (IEA)

polyamine transmembrane transporter activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Atp13a5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	84,881,196 - 85,020,597 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	84,881,230 - 85,020,593 (+)	Ensembl				GRCr8
mRatBN7.2	11	71,376,388 - 71,515,789 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	71,376,422 - 71,515,789 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	80,221,615 - 80,361,226 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	72,856,573 - 72,996,189 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	71,911,008 - 72,050,519 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	74,984,538 - 75,124,249 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	74,984,613 - 75,124,249 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	78,029,982 - 78,168,702 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	73,267,689 - 73,418,786 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	70,339,871 - 70,477,936 (+)	NCBI		Celera
RGSC_v3.1	11	73,325,397 - 73,475,692 (+)	NCBI
Cytogenetic Map	11	q22	NCBI

ATP13A5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	193,274,789 - 193,378,753 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	193,274,789 - 193,378,820 (-)	Ensembl			hg38	GRCh38
GRCh37	3	192,992,578 - 193,096,542 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	194,475,525 - 194,579,208 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	MT	8,479 - 9,206	NCBI
Celera	3	191,408,105 - 191,511,656 (-)	NCBI		Celera
Cytogenetic Map	3	q29	NCBI
HuRef	3	190,379,964 - 190,483,725 (-)	NCBI		HuRef
CHM1_1	3	192,955,701 - 193,059,389 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	195,970,174 - 196,074,132 (-)	NCBI		T2T-CHM13v2.0

Atp13a5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	29,049,242 - 29,208,807 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	29,050,603 - 29,197,550 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	29,230,490 - 29,378,766 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	29,231,851 - 29,378,732 (-)	Ensembl			mm10	GRCm38
MGSCv37	16	29,232,000 - 29,378,818 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	29,151,885 - 29,298,479 (-)	NCBI		MGSCv36	mm8
Celera	16	29,744,008 - 29,891,164 (-)	NCBI		Celera
Cytogenetic Map	16	B2	NCBI
cM Map	16	20.03	NCBI

Atp13a5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	15,200,114 - 15,303,906 (+)	Ensembl
ChiLan1.0	NW_004955420	15,200,164 - 15,303,906 (+)	NCBI	ChiLan1.0	ChiLan1.0

ATP13A5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	191,192,018 - 191,300,494 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	191,196,739 - 191,305,215 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	190,570,844 - 190,675,257 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	200,888,795 - 200,993,217 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	200,889,048 - 200,978,713 (-)	Ensembl			panPan2	panpan1.1

ATP13A5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	24,773,486 - 24,879,022 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	24,774,273 - 24,879,147 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	28,863,491 - 28,969,291 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	24,721,880 - 24,828,014 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	24,722,517 - 24,827,951 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	24,753,697 - 24,859,453 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	24,723,221 - 24,829,318 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	24,964,510 - 25,070,390 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Atp13a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	122,848,497 - 122,962,851 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936711	1,294,892 - 1,402,793 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936711	1,294,974 - 1,402,797 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP13A5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	130,306,570 - 130,420,554 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	130,306,682 - 130,420,542 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	139,829,138 - 139,942,972 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP13A5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	87,357,162 - 87,472,677 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	87,357,409 - 87,451,393 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	61,023,319 - 61,138,613 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp13a5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	64,177,053 - 64,279,732 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	64,177,043 - 64,279,833 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Atp13a5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	14,148,835 - 14,280,875 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Atp13a5
672 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	52
Interacting mature miRNAs:	60
Transcripts:	ENSRNOT00000035049
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	73308487	96070872	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	79618519	99753367	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	58931822	92356038	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	82951028	96351019	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	57754837	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	10	19	133	75	82	57	35	57	6	157	70	4	119	13	62	25	5	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000035049 ⟹ ENSRNOP00000036765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	84,881,230 - 85,020,593 (+)	Ensembl
mRatBN7.2 Ensembl	11	71,376,422 - 71,515,789 (+)	Ensembl
Rnor_6.0 Ensembl	11	74,984,613 - 75,124,249 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103101 ⟹ ENSRNOP00000086336

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	84,881,230 - 85,020,593 (+)	Ensembl
mRatBN7.2 Ensembl	11	71,376,422 - 71,515,789 (+)	Ensembl

RefSeq Acc Id:

NM_001191657 ⟹ NP_001178586

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	84,881,230 - 85,020,593 (+)	NCBI
mRatBN7.2	11	71,376,422 - 71,515,789 (+)	NCBI
Rnor_6.0	11	74,984,613 - 75,124,249 (+)	NCBI
Rnor_5.0	11	78,029,982 - 78,168,702 (+)	NCBI
Celera	11	70,339,871 - 70,477,936 (+)	NCBI

Sequence:

show sequence

GGGCAAGGTGCCAGCGGGTTTTGTAAGCACCTGAGAACAGCGATGACAAGTAGTGCCTGAGTCA
CAGAGGCACAGGTGGCTTTGACAGTGGTCAGAAAGAACCCACACTCGCTGCTCGAGATGGAGAA
GAGCAAGACGGATGGTCACCAGGCTGTGCTCAATGAAGGAGAGGAGAATGAGCTGGAGGTGTTT
GGCTACCAGACTCAGAATTTACGAAGAGCCTTGTGCCTCGTCACAGCCATCCTGACTCTTGGGG
CAGTTCAGCTCATGTTCTACTGGAGGCCTGAGTGGTGGGTGTGGACCAGTTGCATCCCATGCCC
CTTACAAGAAGCAGACATAGTTTTGCTGAGGACAACTGATGAATTTCGAAGATATATGAGGAAA
AAGGTTTTCTGCCTTCACTTATCGACACTGAAGATCCCTATAAGCAAGAACCCAGGGGAACCTC
TGGTAGCTGATCACCACTCGGTCATAAACCAAGCTGTAATGAAGCCAGAATTAAAACTACGATG
CATTCAAGTGCAGAAAATCAGGTACGTGTGGGATTTCTTGAAGAAGCGATTTCAGAAAGTTGGG
TTGCTGGAAGACAGTAACTCCTGCTTTGACATCCACCATACATTTGGATTGGGTCTGACCAGTG
AAGAGCAAGAGGTCAGACGGTTAGTGTGTGGGCCCAATGCTATCGAGGTGGAGATCCAGCCTAT
ATGGAAGCTGCTTGTTAAACAGGTTTTAAATCCATTCTACGTGTTCCAAGCCTTCACCCTCACT
CTATGGCTGTCTCAGGGTTACATAGAATACTCTGTGGCCATCATCATTTTGACTGTTATATCCA
TTGTCTTGAGTGTGTATGACTTGAGACAGCAATCAGTTAAGCTGCACAAGCTTGTGGAGGATCA
CAACAAAGTCCAGGTCACAATCACAGTAAGAGACAAAGGTCTGCAGGAGCTGGAGTCCCGTCTC
CTGGTTCCGGGAGATATTCTCATTCTTCCAGGGAAAATTTCATTGCCCTGTGATGCTGTATTGA
TTGATGGGAGTTGTGTGGTGAATGAAGGAATGCTCACAGGAGAAAGTATACCTGTTACAAAGAC
ACCATTGCCCCAAACGGAGAACACCATGCCCTGGAAATCACACAGTTTGGAGGACTACCGGAAA
CATGTGCTCTTCTGCGGAACAGAAGTGATTCAGGTCAAGCCATCTGGCCAGGGACCTGTTAGAG
CCGTGGTTCTGCAGACAGGTTATAATACAGCAAAAGGAGACTTAGTGAGATCCATCCTCTATCC
CCGACCTCTGAACTTCAAACTGTATAATGATGCCTTCAAGTTCATGGTGTTCCTGGCCTGCATT
GGTGTTGTGGGATTTTTCTATGCCCTAGGTGTCTATTTGTACCATGAAGTTCCTCCGAGAGAAA
CTGTAACCATGGCTCTGATCCTCCTCACTGCCACTGTCCCTCCTGTGCTCCCAGCTGCCCTGAC
CATCGGCAATGTGTATGCCCAGAAGAGGCTGAAGAAGAAGAAGATTTTCTGCATCTCCCCACAG
AGAATCAATATGTGCGGCCAGATCAACCTCGTGTGCTTCGACAAAACAGGAACTCTTACAGAAG
ATGGGCTGGACCTCTGGGGGACGGTTCCCACTGCTGGCAACTGTTTCCAGGCAGTCCACAGCTT
TGCCTCAGGTGAGGCTGTACCCTGGGGCCCACTGTGTGCAGCCATGGCCAGCTGCCACTCCCTG
ATCCTTCTTGATGGGACCATCCAGGGAGACCCTCTGGACCTCAAAATGTTTGAAGGCACTGGCT
GGAATATGGAAGATGGCCAAGTGGCCTCCTGCAAATATAGCACGGCAGATTCCGGCACAGTAAT
AAAACCAGGACCGAACGCTAGCCAGAGTCCCGTGGACAGCATCACCATCTTGCGCCAGTTTCCA
TTTTCCTCAGGACTGCAAAGGATGTCTGTGATTGCTCAGCTGGCTGGTGACCTCCGTCTCCACG
TCTACATGAAGGGTGCCCCGGAAATGGTGGCCAGGTTCTGCAGCTCTGAAACGGTGCCTAAGAA
CTTCCCACAGGAGCTGAGGAATTACACAGTGCAAGGCTTCCGTGTCATCGCTCTTGCCCATAAA
ACCCTGAAGATGGAGAAGGTTTCCGATGTGGAACGTCTAGCAAGGGAGAAAGTGGAGTCCGAGC
TGGCATTTCTGGGTCTTCTCATAATGGAGAATCGCTTGAAAAATGAAACGAGGCCAGTGCTGCA
GGAACTGAGCGAGGCCCGCATCAGGACCGTGATGGTGACAGGTGACAATCTTCAAACTGCCATC
ACTGTTGCTAAAAATTCTGAAATGATTCCTGTGGGCAGCCAGGTCATCATTGTCGAGGCTAATG
AGCCAGGAGACCTTGTTCCTGCTTCTGTGACCTGGCAGCTGGTGGGGACCCAAGAGCCAGGCTC
TGAGAAGAAGGACACCTACATTGATATCGGAAACAGTTCAGTACCTTGTGGGAAAGGTTACCAT
TTTGCAATGAGTGGGAAGTCCTATCAAGTGCTATTTCATCATTTCTACAGCATGCTGCCACAAA
TTCTGGTCAATGGAACCGTTTTTGCAAGAATGTCTCCTGGGCAGAAATCAAGTCTTGTGGAAGA
GTTTCAGAAATTAAATTATTATGTGGGCATGTGTGGAGATGGAGCCAATGACTGTGGGGCTTTG
AAAATGGCGCATGCGGGCATCTCGCTGTCAGAGCAGGAAGCGTCTGTGGCCTCTCCCTTCACCT
CGAAAGTGGCCAATATCGAGTGTGTGCCTCATCTCATCAGGGAGGGACGGGCTGCACTGGTTTC
ATCCTTCGGTGTATTTAAATACTTGACCATGTACGGCATCATCCAGTTTATTGGAACATCACTG
CTGTACTGGCAACTACAGCTCTTCGGTAATTACCAGTATCTCCTGCAAGATGTGGCCATCACCC
TGATGGTCAGCTTAACAATGAGCATAAACCATGCCTACCCGAAGTTGGCTCCATACAGACCAGC
AGGACAACTCCTTTCTCCTCAGTTGCTACTCTCAGTCTTCATGAATTCCTGTTTCACCTGCATT
GTGCTAGTGTGTACGTTTCTCTCTGTGAAACAGCAGCCTTGGTACTGTGAGGTCTACAAATACA
GTGAATGCTTTCTGGTCAACCAAAGTAATTTCTCAACCAACATGGGTTTGGAGCGAAACTGGAC
TGGGAATGCAACCCTGGTTCCTGCTTCGGTGCTAAGTTTCGAGGGCACCACTTTGTGGCCCATT
GTCACCTTCAACTGCATCTCAGCAGCTTTTATTTTTTCTAAGGGAAAGCCATTTCGGAAACCCA
TCTACACCAACTATTTATTCTCGCTTCTGCTGACATCTGCTGTGGGCCTCACTGTTTTCATTCT
GTTTTCTGATTTTCAAGATATATACCGTAGAATGGAGTTCATCCCAACCACAACATCATGGAGA
ATTTCAATTCTGGTGGCAGCCTTTGTCCAGTTCTGTGTGGCATTCTTTGTAGAGGATGCCATCC
TTCAAAATAGAGAGCTCTGGCTGTTTATAAAGAAAGAATTTGGATTCTACTCGAAAAGTCAGTA
TAGGATCTTGCAGAGAAAGCTGGCAGAAGACTCGACGTGGCCTCCCACGAACAGGACAGATTAT
GCAGTCAATGGCAAAAATGGACTCTACATCAACAGAGCCTATGAAAGCCCTGAACAGGTCCCGA
AAGGGAAGCTCAAACTGGGAGGGCAAGCTTCAGAACAGCATTTTTGGACCAGACTGTAACCTGA
ATTGCAGTCACGCCTGATCCACAACATCACCCTTTGTCCCCAAACTAAACATTGTGGAAAGGAG
GAAACTGCATACATATCCTTCTCTTCTCTCTCTGTCGAAGTATCCAATGCACTTCAACATAGCG
ACCCTTGCAGCAAAGAACTTAACATTCATTCTACCCTTCACTAGCTCCAGAGAAACCTGCATGT
CTCAGATCACCTTTGTAATAACCCGTATTCATATTGTATTGTTCTAAATGGACAGCTCTCATGC
AACAAGATTAGATGTATGGACATCGGATGAGAAGAAAAACTGAGAAAGCACTTGGTGTTTGAAA
GTTATAGTAATGTATTAATCGATGTAAGTTTCTTTAGTCTTACATTAATTTGTGGAGCACATTC
ATGTACATACATTGGCCAGGATTATAAGATTCCTCCTGGTTTGCATCTTTGGTGTGACTTAAGT
GGAGAAATAAGATGAATTATTCCACCCTAGGTACACAGGAAGCCAGAGTGGTGTGGAAGTTGAG
AACAGTAGAGATCGGTGCTAATCTTTTATAATCACGGCATGGGTGTTGCTAGGGTGTAAGCAAA
ATACACCAACTTGGTACATTTCAAAAGTATAGTGTATGGGTCTGGGGAGCCTAACAGTGCAGAG
TAGACCAGAATAATGAAATAAACTTTTCAAATGTGTTTTTTCACTTTA

hide sequence

RefSeq Acc Id:

XM_039088300 ⟹ XP_038944228

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	84,881,196 - 85,020,597 (+)	NCBI
mRatBN7.2	11	71,376,388 - 71,515,789 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178586	(Get FASTA)	NCBI Sequence Viewer
	XP_038944228	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL78143	(Get FASTA)	NCBI Sequence Viewer
	EDL78144	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000036765
	ENSRNOP00000036765.6
	ENSRNOP00000086336
	ENSRNOP00000086336.1

RefSeq Acc Id:

NP_001178586 ⟸ NM_001191657

- UniProtKB:

A6JRW3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEKSKTDGHQAVLNEGEENELEVFGYQTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCI
PCPLQEADIVLLRTTDEFRRYMRKKVFCLHLSTLKIPISKNPGEPLVADHHSVINQAVMKPELK
LRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTSEEQEVRRLVCGPNAIEVEI
QPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLV
EDHNKVQVTITVRDKGLQELESRLLVPGDILILPGKISLPCDAVLIDGSCVVNEGMLTGESIPV
TKTPLPQTENTMPWKSHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSI
LYPRPLNFKLYNDAFKFMVFLACIGVVGFFYALGVYLYHEVPPRETVTMALILLTATVPPVLPA
ALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAV
HSFASGEAVPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEGTGWNMEDGQVASCKYSTADSG
TVIKPGPNASQSPVDSITILRQFPFSSGLQRMSVIAQLAGDLRLHVYMKGAPEMVARFCSSETV
PKNFPQELRNYTVQGFRVIALAHKTLKMEKVSDVERLAREKVESELAFLGLLIMENRLKNETRP
VLQELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVIIVEANEPGDLVPASVTWQLVGTQE
PGSEKKDTYIDIGNSSVPCGKGYHFAMSGKSYQVLFHHFYSMLPQILVNGTVFARMSPGQKSSL
VEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKVANIECVPHLIREGRAA
LVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYPKLAPY
RPAGQLLSPQLLLSVFMNSCFTCIVLVCTFLSVKQQPWYCEVYKYSECFLVNQSNFSTNMGLER
NWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYTNYLFSLLLTSAVGLTV
FILFSDFQDIYRRMEFIPTTTSWRISILVAAFVQFCVAFFVEDAILQNRELWLFIKKEFGFYSK
SQYRILQRKLAEDSTWPPTNRTDYAVNGKNGLYINRAYESPEQVPKGKLKLGGQASEQHFWTRL

hide sequence

Ensembl Acc Id:

ENSRNOP00000036765 ⟸ ENSRNOT00000035049

RefSeq Acc Id:	XP_038944228 ⟸ XM_039088300
- Peptide Label:	isoform X1
- UniProtKB:	F1MA70 (UniProtKB/TrEMBL), A6JRW3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000086336 ⟸ ENSRNOT00000103101

Protein Domains

Cation-transporting P-type ATPase N-terminal P5B-type ATPase N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1MA70-F1-model_v2	AlphaFold	F1MA70	1-1216	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306792	AgrOrtholog
BioCyc Gene	G2FUF-20965	BioCyc
Ensembl Genes	ENSRNOG00000024127	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000035049	ENTREZGENE
	ENSRNOT00000035049.7	UniProtKB/TrEMBL
	ENSRNOT00000103101	ENTREZGENE
	ENSRNOT00000103101.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1110.10	UniProtKB/TrEMBL
	3.40.50.1000	UniProtKB/TrEMBL
	Calcium-transporting ATPase, cytoplasmic transduction domain A	UniProtKB/TrEMBL
	Calcium-transporting ATPase, transmembrane domain	UniProtKB/TrEMBL
InterPro	ATPase_P-typ_ATPase-assoc-dom	UniProtKB/TrEMBL
	ATPase_P-typ_cation-transptr_N	UniProtKB/TrEMBL
	ATPase_P-typ_cyto_domN	UniProtKB/TrEMBL
	ATPase_P-typ_ion-transptr	UniProtKB/TrEMBL
	ATPase_P-typ_P_site	UniProtKB/TrEMBL
	ATPase_P-typ_TM_dom	UniProtKB/TrEMBL
	ATPase_P-typ_unknown-pump-sp	UniProtKB/TrEMBL
	HAD-like_sf	UniProtKB/TrEMBL
	HAD_sf	UniProtKB/TrEMBL
	P5A-ATPase_N	UniProtKB/TrEMBL
	P5B-type_ATPase	UniProtKB/TrEMBL
	P_typ_ATPase_HD_dom	UniProtKB/TrEMBL
NCBI Gene	303856	ENTREZGENE
PANTHER	CATION-TRANSPORTING ATPASE 13A5-RELATED	UniProtKB/TrEMBL
	CATION-TRANSPORTING ATPASE-RELATED	UniProtKB/TrEMBL
Pfam	Cation_ATPase	UniProtKB/TrEMBL
	Cation_ATPase_N	UniProtKB/TrEMBL
	E1-E2_ATPase	UniProtKB/TrEMBL
	P5-ATPase	UniProtKB/TrEMBL
PhenoGen	Atp13a5	PhenoGen
PRINTS	CATATPASE	UniProtKB/TrEMBL
	NAKATPASE	UniProtKB/TrEMBL
PROSITE	ATPASE_E1_E2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024127	RatGTEx
Superfamily-SCOP	ATPase_cation_domN	UniProtKB/TrEMBL
	HAD-like_dom	UniProtKB/TrEMBL
	SSF81653	UniProtKB/TrEMBL
	SSF81665	UniProtKB/TrEMBL
UniProt	A0A8I6A7V8_RAT	UniProtKB/TrEMBL
	A6JRW3	ENTREZGENE, UniProtKB/TrEMBL
	F1MA70	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Atp13a5	ATPase 13A5	Atp13a5	ATPase type 13A5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Atp13a5	ATPase type 13A5	RGD1306792_predicted	similar to putative ATPase (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1306792_predicted	similar to putative ATPase (predicted)	LOC303856_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC303856_predicted	similar to putative ATPase (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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