Rrp15 (ribosomal RNA processing 15 homolog) - Rat Genome Database

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Pathways
Gene: Rrp15 (ribosomal RNA processing 15 homolog) Rattus norvegicus
Analyze
Symbol: Rrp15
Name: ribosomal RNA processing 15 homolog
RGD ID: 1306106
Description: Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Orthologous to human RRP15 (ribosomal RNA processing 15 homolog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360895; MGC105708; RGD1306106; ribosomal RNA processing 15 homolog (S. cerevisiae); ribosomal RNA-processing protein 15; RRP15-like protein; similar to RIKEN cDNA 2810430M08
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813100,807,729 - 100,830,812 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13100,807,722 - 100,830,834 (-)EnsemblGRCr8
mRatBN7.21398,276,276 - 98,299,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1398,276,134 - 98,299,370 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13100,793,786 - 100,816,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013102,180,954 - 102,204,035 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01399,376,101 - 99,399,202 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013105,155,824 - 105,178,907 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13105,155,441 - 105,179,095 (-)Ensemblrn6Rnor6.0
Rnor_5.013109,807,397 - 109,830,711 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413102,833,812 - 102,856,894 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1397,784,470 - 97,807,553 (-)NCBICelera
RGSC_v3.113103,022,855 - 103,045,937 (-)NCBI
Cytogenetic Map13q26NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15769876  


Genomics

Comparative Map Data
Rrp15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813100,807,729 - 100,830,812 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13100,807,722 - 100,830,834 (-)EnsemblGRCr8
mRatBN7.21398,276,276 - 98,299,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1398,276,134 - 98,299,370 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13100,793,786 - 100,816,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013102,180,954 - 102,204,035 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01399,376,101 - 99,399,202 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013105,155,824 - 105,178,907 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13105,155,441 - 105,179,095 (-)Ensemblrn6Rnor6.0
Rnor_5.013109,807,397 - 109,830,711 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413102,833,812 - 102,856,894 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1397,784,470 - 97,807,553 (-)NCBICelera
RGSC_v3.113103,022,855 - 103,045,937 (-)NCBI
Cytogenetic Map13q26NCBI
RRP15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,285,293 - 218,337,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,285,290 - 218,337,983 (+)Ensemblhg38GRCh38
GRCh371218,458,635 - 218,511,325 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361216,525,252 - 216,577,948 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1191,675,091 - 191,727,786 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1189,126,828 - 189,179,495 (+)NCBIHuRef
CHM1_11219,730,946 - 219,783,677 (+)NCBICHM1_1
T2T-CHM13v2.01217,520,058 - 217,572,747 (+)NCBIT2T-CHM13v2.0
Rrp15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391186,453,283 - 186,481,555 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1186,453,175 - 186,481,555 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381186,721,086 - 186,749,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,720,978 - 186,749,358 (-)Ensemblmm10GRCm38
MGSCv371188,544,965 - 188,573,237 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361188,421,880 - 188,452,712 (-)NCBIMGSCv36mm8
Celera1193,664,585 - 193,683,559 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.95NCBI
Rrp15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955406262,346 - 296,439 (-)Ensembl
ChiLan1.0NW_004955406260,447 - 295,842 (-)NCBIChiLan1.0ChiLan1.0
RRP15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2131,074,833 - 31,121,954 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1131,037,398 - 31,083,991 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01193,846,921 - 193,900,077 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11198,698,849 - 198,745,011 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1198,698,850 - 198,745,011 (+)EnsemblpanPan2panpan1.1
RRP15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13813,377,518 - 13,416,809 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3813,377,571 - 13,421,810 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3813,419,617 - 13,459,111 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03813,411,023 - 13,450,593 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3813,409,972 - 13,456,853 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13813,420,320 - 13,466,150 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03813,766,942 - 13,812,671 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03814,075,819 - 14,121,556 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rrp15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934458,391,000 - 58,446,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936628408,911 - 456,425 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936628408,854 - 456,464 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRP15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl108,253,822 - 8,303,860 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1108,253,798 - 8,296,143 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21010,300,927 - 10,339,246 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RRP15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12511,273,756 - 11,318,280 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2511,274,241 - 11,318,290 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605511,685,342 - 11,729,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rrp15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248352,314,499 - 2,349,259 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248352,314,341 - 2,355,741 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rrp15
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11064,860,452 - 64,881,320 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rrp15
116 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:47
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000003359
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH130884  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21398,276,305 - 98,276,522 (+)MAPPERmRatBN7.2
Rnor_6.013105,155,854 - 105,156,070NCBIRnor6.0
Rnor_5.013109,807,427 - 109,807,643UniSTSRnor5.0
RGSC_v3.413102,833,842 - 102,834,058UniSTSRGSC3.4
Celera1397,784,500 - 97,784,716UniSTS
RH 3.4 Map13670.0UniSTS
Cytogenetic Map13q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 161 91 90 59 92 59 6 354 190 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003359   ⟹   ENSRNOP00000003359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13100,807,722 - 100,830,834 (-)Ensembl
mRatBN7.2 Ensembl1398,276,134 - 98,299,370 (-)Ensembl
Rnor_6.0 Ensembl13105,155,441 - 105,179,095 (-)Ensembl
RefSeq Acc Id: NM_001009702   ⟹   NP_001009702
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813100,807,729 - 100,830,812 (-)NCBI
mRatBN7.21398,276,276 - 98,299,357 (-)NCBI
Rnor_6.013105,155,824 - 105,178,907 (-)NCBI
Rnor_5.013109,807,397 - 109,830,711 (-)NCBI
RGSC_v3.413102,833,812 - 102,856,894 (-)RGD
Celera1397,784,470 - 97,807,553 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009702 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87649 (Get FASTA)   NCBI Sequence Viewer  
  EDL94933 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003359
  ENSRNOP00000003359.4
GenBank Protein Q5M947 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009702   ⟸   NM_001009702
- UniProtKB: Q5M947 (UniProtKB/Swiss-Prot),   A6JGS7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003359   ⟸   ENSRNOT00000003359

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M947-F1-model_v2 AlphaFold Q5M947 1-280 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699098
Promoter ID:EPDNEW_R9623
Type:multiple initiation site
Name:Rrp15_1
Description:ribosomal RNA processing 15 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013105,178,922 - 105,178,982EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306106 AgrOrtholog
BioCyc Gene G2FUF-16956 BioCyc
Ensembl Genes ENSRNOG00000002450 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003359 ENTREZGENE
  ENSRNOT00000003359.7 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7310706 IMAGE-MGC_LOAD
InterPro Rrp15 UniProtKB/Swiss-Prot
KEGG Report rno:360895 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105708 IMAGE-MGC_LOAD
NCBI Gene 360895 ENTREZGENE
PANTHER PTHR13245 UniProtKB/Swiss-Prot
  RRP15-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Rrp15p UniProtKB/Swiss-Prot
PhenoGen Rrp15 PhenoGen
RatGTEx ENSRNOG00000002450 RatGTEx
UniProt A6JGS7 ENTREZGENE, UniProtKB/TrEMBL
  Q5M947 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-30 Rrp15  ribosomal RNA processing 15 homolog  Rrp15  ribosomal RNA processing 15 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Rrp15  ribosomal RNA processing 15 homolog (S. cerevisiae)  RGD1306106  similar to RIKEN cDNA 2810430M08  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1306106  similar to RIKEN cDNA 2810430M08  RGD1306106_predicted  similar to RIKEN cDNA 2810430M08 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1306106_predicted  similar to RIKEN cDNA 2810430M08 (predicted)  LOC360895_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC360895_predicted  similar to RIKEN cDNA 2810430M08 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL