Gene:	Nck2 ( Rattus norvegicus ) NCK adaptor protein 2
Synonyms:	Nck2_predicted; LOC316369; non-catalytic region of tyrosine kinase adaptor protein 2 (predicted); non-catalytic region of tyrosine kinase adaptor protein 2 ;
ArrayIDs:	1398441_at; rc_AA957410_at; 1390056_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: NCK2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Nck2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Nck2 genome assembly 3.1 9 42651481 - 42778381     Rat Celera Assembly 9 43431063 - 43557015     RGSC genome assembly v3.4 9 42650068 - 42776968     Cytogenetic 9 q22 Mus musculus Nck2 Mouse genome assembly build 36.1 1 43502596 - 43627359     Cytogenetic 1 1 C1 Homo sapiens NCK2 human genome assembly 2 105819871 - 105969244     Human genome assembly build 36.2 2 105727786 - 105877160     Cytogenetic 2 q12   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding (details...)
Biological Process	Gene Ontology positive regulation of T cell proliferation,  positive regulation of actin filament polymerization,  lamellipodium assembly ...  (details...)
Cellular Component	Gene Ontology vesicle membrane (details...)
Pathway	Ontology integrin mediated signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: SH3 IPI SMART: SH2 IPI PROSITE: SH3 IPI PROSITE: SH2 IPI UNIPARC: UPI000018282F IPI KEGG Report: rno:316369 ENTREZGENE HomoloGene Group ID: 20794 ENTREZGENE Germonline: 1305965 Pfam: SH3_1 IPI Pfam: SH2 IPI KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04012 ENTREZGENE InterPro: SH3_region. IPI InterPro: SH3_domain. IPI InterPro: SH2. IPI InterPro: Cytoplasmic_NCK. IPI IPI: IPI00211891 IPI Ensembl Protein: ENSRNOP00000023029 IPI Gene3D-CATH: SH2 IPI PIRSF: Cytoplasmic_NCK IPI Entrez Gene: Nck2 ENTREZGENE Ensembl Genes: ENSRNOG00000017155 IPI Superfamily-SCOP: SH3 IPI PRINTS: SH3DOMAIN. IPI PRINTS: SH2DOMAIN. IPI
Sequences	Nucleotide: NM_001108216 Get FASTA Search GEO Profiles Nucleotide: XM_001059817 Get FASTA Search GEO Profiles Nucleotide: CH473965 Get FASTA Search GEO Profiles Nucleotide: XM_237115 Get FASTA Search GEO Profiles Nucleotide: AY724492 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: NP_001101686 Get FASTA Protein: XP_001059817 Get FASTA Protein: EDL99145 Get FASTA Protein: XP_237115 Get FASTA (View all 4 Protein Accessions)
Clusters	UniGene: 9067
References
Curated References	3 references in RGD related to Nck2
Other References	1 other references at PubMed related to Nck2
Database Information
RGD ID	1305965
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 09-SEP-08: Nck2 NCK adaptor protein 2 Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 30-APR-08: Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 Nck2_predicted non-catalytic region of tyrosine kinase adaptor protein 2 (predicted) APPROVED 'predicted' is removed 2292626 12-JAN-05: Nck2_predicted non-catalytic region of tyrosine kinase adaptor protein 2 (predicted) APPROVED Symbol and Name status set to approved 70820