Igf2bp2 (insulin-like growth factor 2 mRNA binding protein 2) - Rat Genome Database

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Gene: Igf2bp2 (insulin-like growth factor 2 mRNA binding protein 2) Rattus norvegicus
Analyze
Symbol: Igf2bp2
Name: insulin-like growth factor 2 mRNA binding protein 2
RGD ID: 1305614
Description: Predicted to enable N6-methyladenosine-containing RNA reader activity; mRNA binding activity; and translation regulator activity. Predicted to be involved in CRD-mediated mRNA stabilization; negative regulation of translation; and nervous system development. Predicted to act upstream of or within cold-induced thermogenesis and energy homeostasis. Predicted to be located in P-body and cytoskeleton. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2); INTERACTS WITH 17beta-estradiol; atrazine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: insulin-like growth factor 2 mRNA-binding protein 2; LOC303824; RGD1305614; similar to IGF-II mRNA-binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Niddm22
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,378,908 - 92,478,893 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1192,378,908 - 92,478,867 (+)EnsemblGRCr8
mRatBN7.21178,874,402 - 78,974,392 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,874,414 - 78,974,377 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1187,609,203 - 87,709,036 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,262,865 - 80,362,682 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01179,323,549 - 79,423,383 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1194,249,007 - 94,348,821 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1192,447,733 - 92,547,674 (+)NCBILyon_Normotensive
Lyon_Hypertensive1193,369,340 - 93,469,281 (+)NCBILyon_Hypertensive
F344_StmMcwi1192,174,310 - 92,274,122 (+)NCBIF344_StmMcwi
Rnor_6.01182,466,071 - 82,621,105 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,466,071 - 82,621,079 (+)Ensemblrn6Rnor6.0
Rnor_5.01185,557,265 - 85,711,768 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41181,115,320 - 81,216,170 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1177,737,081 - 77,836,862 (+)NCBICelera
RGSC_v3.11181,172,908 - 81,271,988 (+)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
corn oil  (EXP)
Cuprizon  (EXP)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
diquat  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nicotine  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentane-2,3-dione  (EXP)
phenobarbital  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
T-2 toxin  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytoplasmic stress granule  (IBA,IEA,ISO)
cytoskeleton  (IEA,ISO)
cytosol  (IBA,IEA,ISO)
nucleus  (IBA,IEA,ISO)
P-body  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9891060   PMID:15618018   PMID:20080952   PMID:22427968   PMID:22513850   PMID:22658674   PMID:22681889   PMID:37981258  


Genomics

Comparative Map Data
Igf2bp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,378,908 - 92,478,893 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1192,378,908 - 92,478,867 (+)EnsemblGRCr8
mRatBN7.21178,874,402 - 78,974,392 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,874,414 - 78,974,377 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1187,609,203 - 87,709,036 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,262,865 - 80,362,682 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01179,323,549 - 79,423,383 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1194,249,007 - 94,348,821 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1192,447,733 - 92,547,674 (+)NCBILyon_Normotensive
Lyon_Hypertensive1193,369,340 - 93,469,281 (+)NCBILyon_Hypertensive
F344_StmMcwi1192,174,310 - 92,274,122 (+)NCBIF344_StmMcwi
Rnor_6.01182,466,071 - 82,621,105 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,466,071 - 82,621,079 (+)Ensemblrn6Rnor6.0
Rnor_5.01185,557,265 - 85,711,768 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41181,115,320 - 81,216,170 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1177,737,081 - 77,836,862 (+)NCBICelera
RGSC_v3.11181,172,908 - 81,271,988 (+)NCBI
Cytogenetic Map11q23NCBI
IGF2BP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,643,130 - 185,825,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3185,643,130 - 185,825,061 (-)Ensemblhg38GRCh38
GRCh373185,360,918 - 185,542,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,844,221 - 187,025,521 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3183,799,612 - 183,980,726 (-)NCBICelera
Cytogenetic Map3q27.2NCBI
HuRef3182,771,322 - 182,953,823 (-)NCBIHuRef
CHM1_13185,324,446 - 185,505,780 (-)NCBICHM1_1
T2T-CHM13v2.03188,458,961 - 188,640,755 (-)NCBIT2T-CHM13v2.0
Igf2bp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391621,877,759 - 21,982,049 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1621,877,759 - 21,982,049 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381622,059,009 - 22,163,299 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,059,009 - 22,163,299 (-)Ensemblmm10GRCm38
MGSCv371622,059,082 - 22,163,372 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361621,974,311 - 22,078,275 (-)NCBIMGSCv36mm8
Celera1622,626,468 - 22,730,584 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.02NCBI
Igf2bp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542021,818,972 - 21,958,440 (+)Ensembl
ChiLan1.0NW_00495542021,818,970 - 21,957,295 (+)NCBIChiLan1.0ChiLan1.0
IGF2BP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22183,508,305 - 183,689,337 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13183,513,038 - 183,694,052 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03182,667,557 - 182,848,528 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13191,141,289 - 191,320,426 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3191,142,063 - 191,320,221 (-)EnsemblpanPan2panpan1.1
IGF2BP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13418,368,509 - 18,522,233 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3418,369,684 - 18,522,157 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3422,454,233 - 22,609,748 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03418,278,310 - 18,433,934 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3418,278,372 - 18,434,741 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13418,313,763 - 18,469,277 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03418,310,091 - 18,465,396 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03418,539,538 - 18,694,889 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Igf2bp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,979,147 - 118,130,531 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365784,070,955 - 4,222,427 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365784,070,997 - 4,222,661 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2BP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13123,485,628 - 123,650,039 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113123,485,619 - 123,650,050 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,022,551 - 133,065,869 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGF2BP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1153,607,764 - 3,793,386 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl153,607,849 - 3,791,631 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606312,362,256 - 12,547,989 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igf2bp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473070,914,804 - 71,059,642 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473070,914,763 - 71,061,313 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Igf2bp2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v146,736,681 - 6,836,649 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:330
Count of miRNA genes:181
Interacting mature miRNAs:224
Transcripts:ENSRNOT00000036958
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
AW535442  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,974,107 - 78,974,258 (+)MAPPERmRatBN7.2
Rnor_6.01182,620,821 - 82,620,971NCBIRnor6.0
Rnor_5.01185,711,484 - 85,711,634UniSTSRnor5.0
RGSC_v3.41181,215,886 - 81,216,036UniSTSRGSC3.4
Celera1177,836,578 - 77,836,728UniSTS
RH 3.4 Map11650.3UniSTS
Cytogenetic Map11q23UniSTS
RH135376  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,888,010 - 78,888,210 (+)MAPPERmRatBN7.2
Rnor_6.01182,479,954 - 82,480,153NCBIRnor6.0
Rnor_5.01185,571,148 - 85,571,347UniSTSRnor5.0
RGSC_v3.41181,128,997 - 81,129,196UniSTSRGSC3.4
Celera1177,750,663 - 77,750,862UniSTS
RH 3.4 Map11650.7UniSTS
Cytogenetic Map11q23UniSTS
RH141735  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,973,674 - 78,973,872 (+)MAPPERmRatBN7.2
Rnor_6.01182,620,388 - 82,620,585NCBIRnor6.0
Rnor_5.01185,711,051 - 85,711,248UniSTSRnor5.0
RGSC_v3.41181,215,453 - 81,215,650UniSTSRGSC3.4
Celera1177,836,145 - 77,836,342UniSTS
RH 3.4 Map11650.9UniSTS
Cytogenetic Map11q23UniSTS
BE117128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,886,281 - 78,886,444 (+)MAPPERmRatBN7.2
Rnor_6.01182,478,226 - 82,478,388NCBIRnor6.0
Rnor_5.01185,569,420 - 85,569,582UniSTSRnor5.0
RGSC_v3.41181,127,269 - 81,127,431UniSTSRGSC3.4
Celera1177,748,954 - 77,749,116UniSTS
RH 3.4 Map11650.7UniSTS
Cytogenetic Map11q23UniSTS
BF408297  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,928,429 - 78,928,524 (+)MAPPERmRatBN7.2
Rnor_6.01182,575,535 - 82,575,629NCBIRnor6.0
Rnor_6.01182,520,255 - 82,520,349NCBIRnor6.0
Rnor_5.01185,666,198 - 85,666,292UniSTSRnor5.0
Rnor_5.01185,610,918 - 85,611,012UniSTSRnor5.0
RGSC_v3.41181,169,814 - 81,169,908UniSTSRGSC3.4
Celera1177,791,173 - 77,791,267UniSTS
RH 3.4 Map11651.8UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 156 91 90 59 72 59 6 336 172 11 135 81 91 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000036958   ⟹   ENSRNOP00000037578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1192,378,908 - 92,478,867 (+)Ensembl
mRatBN7.2 Ensembl1178,874,414 - 78,974,377 (+)Ensembl
Rnor_6.0 Ensembl1182,466,071 - 82,621,079 (+)Ensembl
RefSeq Acc Id: NM_001270598   ⟹   NP_001257527
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,378,908 - 92,478,893 (+)NCBI
mRatBN7.21178,874,402 - 78,974,392 (+)NCBI
Dahl_SR_JrHsd1194,249,007 - 94,348,821 (+)NCBI
Lyon_Normotensive1192,447,733 - 92,547,674 (+)NCBI
Lyon_Hypertensive1193,369,340 - 93,469,281 (+)NCBI
F344_StmMcwi1192,174,310 - 92,274,122 (+)NCBI
Rnor_6.01182,466,071 - 82,621,105 (+)NCBI
Rnor_5.01185,557,265 - 85,711,768 (+)NCBI
Celera1177,737,081 - 77,836,862 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270599   ⟹   NP_001257528
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,378,908 - 92,478,893 (+)NCBI
mRatBN7.21178,874,402 - 78,974,392 (+)NCBI
Dahl_SR_JrHsd1194,249,007 - 94,348,821 (+)NCBI
Lyon_Normotensive1192,447,733 - 92,547,674 (+)NCBI
Lyon_Hypertensive1193,369,340 - 93,469,281 (+)NCBI
F344_StmMcwi1192,174,310 - 92,274,122 (+)NCBI
Rnor_6.01182,466,071 - 82,621,105 (+)NCBI
Rnor_5.01185,557,265 - 85,711,768 (+)NCBI
Celera1177,737,081 - 77,836,862 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001257527 (Get FASTA)   NCBI Sequence Viewer  
  NP_001257528 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78047 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000037578
  ENSRNOP00000037578.6
RefSeq Acc Id: NP_001257527   ⟸   NM_001270598
- Peptide Label: isoform 1
- UniProtKB: D3ZWZ6 (UniProtKB/TrEMBL),   A6JS60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257528   ⟸   NM_001270599
- Peptide Label: isoform 2
- Sequence:
Ensembl Acc Id: ENSRNOP00000037578   ⟸   ENSRNOT00000036958
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZWZ6-F1-model_v2 AlphaFold D3ZWZ6 1-592 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698258
Promoter ID:EPDNEW_R8783
Type:initiation region
Name:Igf2bp2_1
Description:insulin-like growth factor 2 mRNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01182,466,079 - 82,466,139EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305614 AgrOrtholog
BioCyc Gene G2FUF-20796 BioCyc
Ensembl Genes ENSRNOG00000025946 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036958 ENTREZGENE
  ENSRNOT00000036958.8 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  3.30.310.210 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro IGF2BP2_RRM1 UniProtKB/TrEMBL
  IPR004087 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  KH_type_1 UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
KEGG Report rno:303824 UniProtKB/TrEMBL
NCBI Gene 303824 ENTREZGENE
PANTHER KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen Igf2bp2 PhenoGen
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025946 RatGTEx
SMART RRM UniProtKB/TrEMBL
  SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A6JS60 ENTREZGENE, UniProtKB/TrEMBL
  D3ZWZ6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Igf2bp2  insulin-like growth factor 2 mRNA binding protein 2  RGD1305614_predicted  similar to IGF-II mRNA-binding protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1305614_predicted  similar to IGF-II mRNA-binding protein 2 (predicted)  LOC303824_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303824_predicted  similar to IGF-II mRNA-binding protein 2 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL