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Gene: Adgrb1 (adhesion G protein-coupled receptor B1) Rattus norvegicus

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Symbol:

Adgrb1 (Ensembl: AABR07058422.1)

Name:

adhesion G protein-coupled receptor B1

RGD ID:

1305608

Description:

Predicted to enable several functions, including PDZ domain binding activity; lipopolysaccharide binding activity; and phosphatidylserine binding activity. Involved in postsynaptic actin cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic membrane. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Bai1; brain-specific angiogenesis inhibitor 1; LOC362931

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	108,293,681 - 108,365,892 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	108,293,818 - 108,365,870 (+)	Ensembl				GRCr8
mRatBN7.2	7	106,404,827 - 106,476,902 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	106,404,958 - 106,476,902 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	108,175,524 - 108,234,904 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	110,397,026 - 110,456,403 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	110,345,121 - 110,404,495 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	115,766,484 - 115,828,514 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	115,675,214 - 115,734,250 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	112,622,235 - 112,682,897 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	102,819,252 - 102,878,228 (+)	NCBI		Celera
RGSC_v3.1	7	112,656,235 - 112,717,613 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colorectal cancer (ISO)

glioblastoma (ISO)

invasive ductal carcinoma (ISO)

Lymphatic Metastasis (ISO)

malignant astrocytoma (ISO)

Neoplasm Metastasis (ISO)

pancreatic adenocarcinoma (ISO)

renal cell carcinoma (ISO)

stomach cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-naringenin (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-nitrophenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aldehydo-D-glucose (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbon nanotube (ISO)

choline (ISO)

D-glucose (ISO)

decabromodiphenyl ether (EXP)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

elemental selenium (ISO)

ethanol (ISO)

ethylparaben (ISO)

folic acid (ISO)

fructose (ISO)

gentamycin (EXP)

glucose (ISO)

indole-3-methanol (EXP)

L-methionine (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

maneb (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (ISO)

paraquat (ISO)

pentanal (ISO)

perfluorohexanesulfonic acid (ISO)

propanal (ISO)

quercetin (ISO)

quercitrin (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

triclosan (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic cell clearance (IEA,ISO)

cell surface receptor signaling pathway (IEA)

defense response to Gram-negative bacterium (IEA,ISO)

engulfment of apoptotic cell (IBA,IEA,ISO)

G protein-coupled receptor signaling pathway (IBA,IEA)

immune system process (IEA)

innate immune response (IEA)

muscle organ development (IEA)

negative regulation of angiogenesis (IEA,ISO)

negative regulation of endothelial cell migration (IEA,ISO)

negative regulation of protein catabolic process (IEA,ISO)

negative regulation of protein ubiquitination (IEA,ISO)

nervous system development (IEA)

phagocytosis (IEA)

phagocytosis, engulfment (IEA,ISO)

phagocytosis, recognition (IEA,ISO)

positive regulation of myoblast fusion (IEA,ISO)

positive regulation of reactive oxygen species biosynthetic process (IEA,ISO)

positive regulation of synapse assembly (ISO)

postsynaptic actin cytoskeleton organization (IDA,IMP)

regulation of synaptic plasticity (IEA,ISO)

signal transduction (IEA)

Cellular Component

cell junction (IEA)

dendrite (IBA,IEA,ISO)

dendritic spine (IEA)

extracellular region (IEA)

extracellular space (IEA,ISO)

focal adhesion (IEA,ISO)

glutamatergic synapse (IDA,IEP,IMP)

membrane (IEA)

perinuclear region of cytoplasm (IEA,ISO)

phagocytic cup (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

postsynaptic density (IBA,IEA,ISO)

postsynaptic membrane (IDA,IEP,IMP)

Molecular Function

G protein-coupled receptor activity (IBA,IEA,ISO)

lipopolysaccharide binding (IEA,ISO)

PDZ domain binding (IEA,ISO)

phosphatidylserine binding (IEA,ISO)

protein binding (IPI,ISO)

transmembrane signaling receptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

p53 signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis.	Duda DG, etal., Br J Cancer. 2002 Feb 1;86(3):490-6. doi: 10.1038/sj.bjc.6600067.
2.	The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.	Duman JG, etal., J Neurosci. 2013 Apr 17;33(16):6964-78. doi: 10.1523/JNEUROSCI.3978-12.2013.
3.	Brain-specific angiogenesis inhibitor 1 expression is inversely correlated with vascularity and distant metastasis of colorectal cancer.	Fukushima Y, etal., Int J Oncol. 1998 Nov;13(5):967-70.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Brain-specific angiogenesis inhibitor 1 is a putative factor for inhibition of neovascular formation in renal cell carcinoma.	Izutsu T, etal., J Urol. 2011 Jun;185(6):2353-8. doi: 10.1016/j.juro.2011.02.019. Epub 2011 Apr 21.
7.	Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas.	Kang X, etal., Cancer Gene Ther. 2006 Apr;13(4):385-92. doi: 10.1038/sj.cgt.7700898.
8.	Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression.	Kaur B, etal., Am J Pathol. 2003 Jan;162(1):19-27. doi: 10.1016/S0002-9440(10)63794-7.
9.	Comparative study of angiostatic and anti-invasive gene expressions as prognostic factors in gastric cancer.	Lee JH, etal., Int J Oncol. 2001 Feb;18(2):355-61.
10.	Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.	Meisen WH, etal., Mol Cancer Ther. 2015 Jan;14(1):307-14. doi: 10.1158/1535-7163.MCT-14-0659. Epub 2014 Nov 5.
11.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
12.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
13.	GOA pipeline	RGD automated data pipeline
14.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
16.	Expression of brain-specific angiogenesis inhibitor 1 is inversely correlated with pathological grade, angiogenesis and peritumoral brain edema in human astrocytomas.	Wang W, etal., Oncol Lett. 2013 May;5(5):1513-1518. doi: 10.3892/ol.2013.1250. Epub 2013 Mar 12.

Additional References at PubMed

PMID:8889548	PMID:15782143	PMID:17960134	PMID:19176395	PMID:20888903	PMID:21245295	PMID:22330140	PMID:23615608	PMID:23782696	PMID:24509909	PMID:24613359	PMID:25751059
PMID:26838550

Genomics

Comparative Map Data

Adgrb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	108,293,681 - 108,365,892 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	108,293,818 - 108,365,870 (+)	Ensembl				GRCr8
mRatBN7.2	7	106,404,827 - 106,476,902 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	106,404,958 - 106,476,902 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	108,175,524 - 108,234,904 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	110,397,026 - 110,456,403 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	110,345,121 - 110,404,495 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	115,766,484 - 115,828,514 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	115,675,214 - 115,734,250 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	112,622,235 - 112,682,897 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	102,819,252 - 102,878,228 (+)	NCBI		Celera
RGSC_v3.1	7	112,656,235 - 112,717,613 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

ADGRB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	142,449,649 - 142,545,007 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	142,449,430 - 142,545,009 (+)	Ensembl			hg38	GRCh38
GRCh37	8	143,531,010 - 143,626,368 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	143,542,379 - 143,623,370 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	143,542,378 - 143,623,369	NCBI
Celera	8	139,855,778 - 139,937,685 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	ENTREZGENE
HuRef	8	138,802,096 - 138,882,338 (+)	NCBI		HuRef
CHM1_1	8	143,585,613 - 143,666,276 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	143,591,907 - 143,688,308 (+)	NCBI		T2T-CHM13v2.0

Adgrb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	74,388,045 - 74,461,314 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	74,388,044 - 74,461,314 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	74,516,196 - 74,589,465 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	74,516,195 - 74,589,465 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	74,346,626 - 74,419,894 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	74,343,939 - 74,416,478 (+)	NCBI		MGSCv36	mm8
Celera	15	76,016,847 - 76,094,001 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	34.22	NCBI

Adgrb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	1,237,363 - 1,314,127 (+)	Ensembl
ChiLan1.0	NW_004955454	1,250,261 - 1,313,547 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADGRB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	159,880,740 - 159,977,860 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	135,403,850 - 135,501,242 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	139,154,065 - 139,251,115 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	142,221,371 - 142,277,665 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	142,220,827 - 142,301,070 (+)	Ensembl			panPan2	panpan1.1

ADGRB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	36,627,791 - 36,649,013 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	36,614,498 - 36,690,936 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	36,495,752 - 36,557,393 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	37,023,275 - 37,084,917 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	37,023,070 - 37,084,917 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	36,742,111 - 36,803,620 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	36,831,945 - 36,893,408 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	37,253,730 - 37,315,304 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC101964702
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	1,864,971 - 1,887,131 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	9,248,319 - 9,313,230 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	9,247,749 - 9,313,230 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADGRB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	1,582,330 - 1,658,942 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	1,582,321 - 1,658,639 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ADGRB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	136,704,318 - 136,784,581 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	136,704,341 - 136,783,991 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	3,266,514 - 3,311,250 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adgrb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	14,050,213 - 14,113,534 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624735	14,049,621 - 14,126,287 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Adgrb1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	247,262,594 - 247,334,161 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Adgrb1
219 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1331723	Bw25	Body weight QTL 25	3.348		body mass (VT:0001259)	body weight (CMO:0000012)	7	96700404	111672180	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	63889858	108889858	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	63889858	108889858	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
3	18	46	8	74	35	10	45	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001170597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BF417969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB581992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB738223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

NM_001170597 ⟹ NP_001164068

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,818 - 108,365,892 (+)	NCBI
mRatBN7.2	7	106,404,827 - 106,476,902 (+)	NCBI
Rnor_6.0	7	115,766,484 - 115,828,514 (+)	NCBI
Rnor_5.0	7	115,675,214 - 115,734,250 (+)	NCBI
Celera	7	102,819,252 - 102,878,228 (+)	NCBI

Sequence:

show sequence

AGCTACCATTGGAAGCCACAGGCAAGCACCAGGAACCTGGACTTTAGGAGTCATTGCTGGTCTC
ACTGTCTCCTGAAACCCTGCCCTGTCCCCACCTTGCCTTCACCCAGCCCCTGCCTCTGGCTCAC
TGCCCTGGACGGCCCTGCCTGCTGCCGGACCCTGGCATGTCAAGGCCTGGCCTGCACTTGCCTG
CCCAGCCCGCGGAACCCCAGCGGCCCCGCGAGCTAGGATGAGGGGCCAGGCTGCTGCCCCGGGC
CCCATCTGGATCCTTGCTCCACTCCTGCTGTTACTATTGCTACTGGGGCGCTGGGCACGTGCTG
CCTCTGGGGCAGACATAGGGCCTGGGACAGAGCAGTGCACCACATTGGTGCAGGGCAAGTTCTT
CGGATACTTCTCCGCGGCTGCTGTGTTTCCAGCCAACGCCTCACGCTGCTCTTGGACTCTTCGC
AACCCGGACCCTCGTCGTTACACGCTCTACATGAAGGTGGCCAAGGCACCTGCACCCTGCAGCG
GCCCTGGCCGAGTTCGCACCTACCAGTTCGACTCTTTCTTGGAATCCACGCGCACCTACCTGGG
TGTGGAGAGCTTTGACGAAGTTCTGCGGCTCTGCGATCCCTCTGCACCCCTAGCCTTCCTGCAG
GCCAGCAAACAGTTCCTACAGATGCAGCGCCAACAGCCACCCCAAGATGGTGACCTTGGTCCCC
AGGGCTCTGGTGACGACTTCTCTGTGGAGTACCTGGTGGTGGGCAATCGCAACCCCAGCCACGC
TGCCTGTCAGATGCTGTGCCGTTGGCTGGATGCCTGTCTAGCTGGCAGCCGCAGCTCACACCCC
TGTGGCATCATGCAGACTCCCTGTGCCTGCCTGGGTGGAGAAGCTGGAGACACTGCTTCCAGCC
CCTTGGTCCCCCGTGGGGACGTCTGCTTGAGAGACGGCGTAGCTGGTGGCCCTGAGAACTGCCT
CACCAGCCTGACCCAGGACCGAGGTGGGCACGGCTCAGCAGGTGGCTGGAAACTGTGGTCCTTG
TGGGGCGAATGTACGCGGGACTGCGGGGGAGGCCTACAAACTCGAACCCGCACTTGCTCGCCCA
CCCTTGGCGTGGAGGGCAGAGGCTGTGAGGGCGTTCTGGAAGAAGGCCGCCTGTGCAATCGCAA
GGCCTGCGGTCCCACTGGGCGCACCAGCTCACGGAGCCAGTCCCTGAGGTCCACGGATGCCCGG
CGTCGTGAGGAGTTTGGGGATGAGCTGCAACAGTTTGGGTTCCCATCCCCCCAGACTGGTGACC
CAGCAGCTGAGGAGTGGTCCCCATGGAGCGTATGCTCCAGCACCTGTGGCGAGGGATGGCAGAC
CCGTACGCGCTTCTGCGTGTCATCCTCGTACAGTACTCAGTGCAGTGGACCTCTGAGGGAGCAG
CGGCTCTGCAACAACTCAGCAGTGTGTCCAGTGCATGGAGCCTGGGATGAGTGGTCACCCTGGA
GCCTCTGCTCCAGTACCTGTGGCCGTGGCTTCCGTGACCGTACTCGCACTTGCAGGCCCCCTCA
GTTTGGAGGCAACCCCTGTGAGGGTCCGGAGAAGCAAACCAAGTTCTGCAACATTGCCCTGTGC
CCTGGCCGGGCAGTGGACGGAAACTGGAATGAATGGTCCAGCTGGAGCACCTGCTCTGCCAGTT
GCTCCCAAGGCCGCCAGCAACGGACCCGGGAGTGCAATGGTCCTTCCTATGGGGGTGCCGAGTG
CCAGGGCCACTGGGTGGAGACTCGAGACTGCTTCCTGCAGCAATGCCCAGTGGACGGCAAATGG
CAGGCCTGGGCATCATGGGGCAGCTGCAGCGTCACGTGTGGAGGTGGAAGCCAGCGACGGGAGC
GTGTCTGCTCTGGACCTTTCTTTGGGGGAGCAGCCTGCCAGGGCCCCCAAGATGAGTACCGACA
GTGTGGCGCTCAGCGATGTCCCGAGCCCCATGAGATTTGTGATGAGGACAACTTTGGGGCCGTG
GTCTGGAAGGAGACCCCAGCTGGAGAGGTGGCTGCAGTCCGGTGTCCCCGCAATGCCACAGGCC
TTATCCTGCGCCGCTGTGAGCTGGACGAGGAGGGCATCGCCTTCTGGGAGCCACCCACCTACAT
CCGCTGTGTCTCCATTGACTACCGGAACATCCAGATGATGACCCGAGAGCACCTGGCGAAGGCG
CAGCGGGGGCTGCCAGGGGAGGGGGTCTCAGAGGTCATCCAGACACTGCTGGAGATCTCACAGG
ATGGCACCAGCTACAGCGGCGACCTGCTCTCCACCATCGATGTCCTGAGGAACATGACAGAGAT
CTTCCGCAGGGCTTACTATAGCCCCACACCCGGGGATGTGCAGAACTTTGTCCAGATCATCAGC
AACCTGCTGGCGGAGGAGAACCGGGACAAGTGGGAGGAGGCACAGCTGATGGGCCCCAACGCCA
AGGAGCTCTTTCGACTGGTGGAAGACTTTGTGGATGTCATCGGCTTCCGCATGAAGGATTTGAG
GGATGCCTACCAGGTGACAGACAATCTGGTGCTCAGCATCCACAAGCTTCCAGCCAGTGGGGCC
ACCGACATCAGTTTCCCTATGAAGGGCTGGCGTGCCACTGGAGACTGGGCCAAGGTGCCAGAGG
ACAGGGTCACCGTGTCCAAGAGTGTGTTTTCCACAGGGCTGGCAGAAGCTGACGATTCATCTGT
GTTCGTGGTTGGTACTGTGCTCTACCGGAACTTGGGCAGCTTCCTAGCCCTGCAGAGGAACACA
ACTGTCCTCAACTCTAAGGTCATCTCCGTGACTGTGAAGCCCCCACCTCGATCGCTCCTCACAC
CCTTGGAGATCGAGTTCGCCCACATGTACAATGGCACCACCAACCAGACTTGTATCCTGTGGGA
TGAGACAGATGGACCCTCCTCCTCCGCCCCCCCGCAGCTCGGGCCCTGGTCGTGGCGCGGCTGC
CGCACGGTGCCCCTCGATGCCCTCCGGACGCGCTGCCTGTGTGACCGGCTCTCCACCTTCGCCA
TCTTAGCCCAGCTCAGCGCCGACGCGACCATGGATAAGGTGACCGTGCCATCTGTGACGCTCAT
CGTGGGCTGTGGCGTGTCTTCCCTCACCCTGCTCATGCTGGTCATCATCTACGTGTCTGTGTGG
AGGTACATTCGCTCAGAGCGGTCCGTCATCCTCATCAACTTCTGCCTGTCCATCATCTCCTCTA
ATGCCCTCATTCTCATTGGGCAGACCCAGACCCGCAACAAGGTTGTGTGCACACTGGTGGCTGC
CTTTTTGCACTTCTTCTTCCTGTCCTCATTCTGCTGGGTGCTCACCGAGGCCTGGCAATCCTAC
ATGGCTGTCACCGGCCGCCTCCGGAGCCGGCTCGTCCGCAAGCGCTTTCTCTGCCTGGGCTGGG
GGCTCCCTGCGCTGGTGGTGGCCATTTCTGTGGGATTCACCAAGGCCAAGGGGTACAGCACCAT
GAACTATTGCTGGCTCTCCCTGGAGGGGGGACTTCTGTATGCCTTCGTGGGACCGGCTGCTGCA
GTTGTGCTGGTGAACATGGTGATCGGGATCCTGGTGTTCAACAAGCTCGTGTCCAAGGACGGCA
TCACGGACAAGAAGCTGAAGGAGCGGGCAGGGGCCTCCCTGTGGAGCTCCTGCGTGGTGCTGCC
GCTGCTGGCGCTGACCTGGATGTCTGCTGTGCTTGCTGTCACCGACCGCCGCTCCGCCCTCTTC
CAGATCCTCTTCGCTGTCTTCGACTCACTGGAGGGCTTCGTCATCGTGATGGTGCACTGCATTC
TGCGAAGAGAGGTCCAGGATGCTGTGAAGTGTCGTGTGGTAGATCGACAAGAGGAGGGCAACGG
GGACTCGGGGGGCTCCTTCCAGAACGGCCACGCTCAGCTCATGACCGACTTTGAGAAGGATGTG
GATCTGGCCTGTAGATCAGTGCTGAACAAAGACATTGCAGCCTGCCGCACGGCAACTATCACAG
GTACCTTCAAGCGACCATCACTGCCTGAAGAGGAGAAGATGAAGCTGGCCAAGGGCCCACCCCC
CACCTTCAACAGCCTACCAGCTAATGTGTCCAAGCTGCACCTGCACGGTTCACCCCGCTACCCC
GGTGGGCCACTGCCTGACTTCCCCAACCATTCACTCACCCTTAAAAAGGACAAGGCCCCCAAGT
CCTCTTTTATTGGTGATGGGGACATCTTTAAGAAACTGGACTCTGAGCTGAGCCGGGCCCAGGA
GAAGGCTCTGGACACGAGCTACGTGATCCTGCCCACGGCCACGGCCACACTCCGGCCCAAACCC
AAGGAGGAACCCAAATACAGCATCAACATTGACCAGATGCCCCAAACCCGACTCATCCACCTTA
GCATGGCGCCCGACGCCAGCTTCCCTACCCGAAGCCCACCTGCCCGTGAGCCCCCAGGTGGTGC
ACCCCCTGAGGTGCCCCCTGTCCAGCCACCACCACCACCTCCACCACCCCCTCCACCCCAACAG
CCCATACCCCCACCACCCTCCCTGGAGCCTGCACCTCCCAGCCTGGGGGACACAGGGGAGCCTT
CGGCCCACCCAGGACCCAGTTCAGGTGCTGGGACCAAGAATGAGAACGTGGCCACCTTGTCAGT
GAGCTCCTTGGAGCGGCGGAAATCACGGTATGCAGAACTGGACTTCGAGAAGATCATGCACACA
CGGAAGCGACACCAGGACATGTTCCAGGACCTGAACCGGAAGCTGCAGCATGCGGCTGAGAAGG
AGAAGGAGGTGCCAGGCGTAGACAACAAGCCAGAGAAGCAGCAAACTCCCAACAAGAGGGCCTG
GGAGAGCCTCCGCAAGCCCCATGGGACACCCGCTTGGGTAAAGAAGGAGCTGGAGCCACTGCCC
CCGTCTCCATTGGAGCTGCGGAGTGTGGAGTGGGAGAAGGCGGGTGCCACCATCCCACTGGTTG
GCCAGGACATCATCGACCTCCAGACCGAGGTCTGAGCGGGCGGGCCGTGGCCCCACACCGGGCC
AGGAGGTGGGATGCTGCTCTGCCCGCTCCGCCATAGGACGGGCACAGATGCGCTCGCGGTGGCG
GGCCGGGTCCAGCCCCGGCCTCAGGGCGCTCAGAGGCGGCCAGGCAGAGGGCCCGCGGTGCTGG
GACCAGAGCCAGACACAGGACAGGAGGTGGCATGGCCGGCGGGCACAGGGATCCAGAGGCCGGA
TGGTGCCTCAGACTCTGCCCTCCTTGGGCAACCCCGGGCAGGCAGGCAAGCGGCTGTGGACATG
GACAGGCCTGGTGTGGCCAGCGTCCCCAGGATGCCCACCTCAGCCACCACTGCAGAGGACTGCC
TGCGGCCCACCAGCCTGGCTCCGATTTTTAGATACCCCCTACCCCTTGGGAAGCAGCCAGACCC
CCCCACTCCCTTCCAGGACCCTGGGCCCCTCCCAGACCCAGGCAGAGAGCATGGTCCTGACCCA
GAGCCCCCCGGGGCAGGACTGAGACCACTCTGGAAAGAAGCAGGGTGGGGAATCTATTTTTTCT
CTCCTTTTCTTTTCTTCAATAAAAAGAATTAAAAACCCA

hide sequence

RefSeq Acc Id:

XM_039079532 ⟹ XP_038935460

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,817 - 108,365,892 (+)	NCBI
mRatBN7.2	7	106,404,860 - 106,476,902 (+)	NCBI

RefSeq Acc Id:

XM_063263857 ⟹ XP_063119927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,816 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263858 ⟹ XP_063119928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,818 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263859 ⟹ XP_063119929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,821 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263860 ⟹ XP_063119930

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,823 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263861 ⟹ XP_063119931

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,823 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263862 ⟹ XP_063119932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,681 - 108,354,149 (+)	NCBI

RefSeq Acc Id:

XM_063263863 ⟹ XP_063119933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,340,116 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263864 ⟹ XP_063119934

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,339,838 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263865 ⟹ XP_063119935

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,340,116 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263866 ⟹ XP_063119936

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,340,116 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263867 ⟹ XP_063119937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,339,841 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263868 ⟹ XP_063119938

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,340,116 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XM_063263869 ⟹ XP_063119939

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,339,843 - 108,365,892 (+)	NCBI

RefSeq Acc Id:

XR_010053007

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	108,293,681 - 108,360,824 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001164068	(Get FASTA)	NCBI Sequence Viewer
	XP_038935460	(Get FASTA)	NCBI Sequence Viewer
	XP_063119927	(Get FASTA)	NCBI Sequence Viewer
	XP_063119928	(Get FASTA)	NCBI Sequence Viewer
	XP_063119929	(Get FASTA)	NCBI Sequence Viewer
	XP_063119930	(Get FASTA)	NCBI Sequence Viewer
	XP_063119931	(Get FASTA)	NCBI Sequence Viewer
	XP_063119932	(Get FASTA)	NCBI Sequence Viewer
	XP_063119933	(Get FASTA)	NCBI Sequence Viewer
	XP_063119934	(Get FASTA)	NCBI Sequence Viewer
	XP_063119935	(Get FASTA)	NCBI Sequence Viewer
	XP_063119936	(Get FASTA)	NCBI Sequence Viewer
	XP_063119937	(Get FASTA)	NCBI Sequence Viewer
	XP_063119938	(Get FASTA)	NCBI Sequence Viewer
	XP_063119939	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	C0HL12	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000077654
	ENSRNOP00000096011

RefSeq Acc Id:	NP_001164068 ⟸ NM_001170597
- Peptide Label:	precursor
- UniProtKB:	C0HL12 (UniProtKB/Swiss-Prot), A0A8I5ZZU7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRGQAAAPGPIWILAPLLLLLLLLGRWARAASGADIGPGTEQCTTLVQGKFFGYFSAAAVFPAN ASRCSWTLRNPDPRRYTLYMKVAKAPAPCSGPGRVRTYQFDSFLESTRTYLGVESFDEVLRLCD PSAPLAFLQASKQFLQMQRQQPPQDGDLGPQGSGDDFSVEYLVVGNRNPSHAACQMLCRWLDAC LAGSRSSHPCGIMQTPCACLGGEAGDTASSPLVPRGDVCLRDGVAGGPENCLTSLTQDRGGHGS AGGWKLWSLWGECTRDCGGGLQTRTRTCSPTLGVEGRGCEGVLEEGRLCNRKACGPTGRTSSRS QSLRSTDARRREEFGDELQQFGFPSPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYST QCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQ TKFCNIALCPGRAVDGNWNEWSSWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFL QQCPVDGKWQAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCPEPHEI CDEDNFGAVVWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAFWEPPTYIRCVSIDYRNIQM MTREHLAKAQRGLPGEGVSEVIQTLLEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGD VQNFVQIISNLLAEENRDKWEEAQLMGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLS IHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLAEADDSSVFVVGTVLYRNLG SFLALQRNTTVLNSKVISVTVKPPPRSLLTPLEIEFAHMYNGTTNQTCILWDETDGPSSSAPPQ LGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADATMDKVTVPSVTLIVGCGVSSLTLLM LVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCW VLTEAWQSYMAVTGRLRSRLVRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGLL YAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLA VTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQ LMTDFEKDVDLACRSVLNKDIAACRTATITGTFKRPSLPEEEKMKLAKGPPPTFNSLPANVSKL HLHGSPRYPGGPLPDFPNHSLTLKKDKAPKSSFIGDGDIFKKLDSELSRAQEKALDTSYVILPT ATATLRPKPKEEPKYSINIDQMPQTRLIHLSMAPDASFPTRSPPAREPPGGAPPEVPPVQPPPP PPPPPPPQQPIPPPPSLEPAPPSLGDTGEPSAHPGPSSGAGTKNENVATLSVSSLERRKSRYAE LDFEKIMHTRKRHQDMFQDLNRKLQHAAEKEKEVPGVDNKPEKQQTPNKRAWESLRKPHGTPAW VKKELEPLPPSPLELRSVEWEKAGATIPLVGQDIIDLQTEV hide sequence

RefSeq Acc Id:	XP_038935460 ⟸ XM_039079532
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5Y6L4 (UniProtKB/TrEMBL), A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119932 ⟸ XM_063263862
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063119927 ⟸ XM_063263857
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119928 ⟸ XM_063263858
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119929 ⟸ XM_063263859
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119931 ⟸ XM_063263861
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119930 ⟸ XM_063263860
- Peptide Label:	isoform X5
- UniProtKB:	C0HL12 (UniProtKB/Swiss-Prot), A0A8I5ZZU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119934 ⟸ XM_063263864
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063119937 ⟸ XM_063263867
- Peptide Label:	isoform X10

RefSeq Acc Id:	XP_063119939 ⟸ XM_063263869
- Peptide Label:	isoform X11
- UniProtKB:	A0A8I6ASL1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119933 ⟸ XM_063263863
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063119935 ⟸ XM_063263865
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063119936 ⟸ XM_063263866
- Peptide Label:	isoform X10

RefSeq Acc Id:	XP_063119938 ⟸ XM_063263868
- Peptide Label:	isoform X11
- UniProtKB:	A0A8I6ASL1 (UniProtKB/TrEMBL)

Protein Domains

G-protein coupled receptors family 2 profile GAIN-B TSP type-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-C0HL12-F1-model_v2	AlphaFold	C0HL12	1-1577	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305608	AgrOrtholog
BioCyc Gene	G2FUF-33038	BioCyc
Ensembl Genes	ENSRNOG00000029450	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000076127	ENTREZGENE
	ENSRNOT00000076380	ENTREZGENE
Gene3D-CATH	1.25.40.610	UniProtKB/Swiss-Prot
	2.20.100.10	UniProtKB/Swiss-Prot
	2.60.220.50	UniProtKB/Swiss-Prot
	4.10.1240.10	UniProtKB/Swiss-Prot
	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	AGRB_N	UniProtKB/Swiss-Prot
	GAIN_B	UniProtKB/Swiss-Prot
	GAIN_dom_N	UniProtKB/Swiss-Prot
	GAIN_dom_sf	UniProtKB/Swiss-Prot
	GPCR_2-like	UniProtKB/Swiss-Prot
	GPCR_2_brain_angio_inhib	UniProtKB/Swiss-Prot
	GPCR_2_extracell_dom_sf	UniProtKB/Swiss-Prot
	GPCR_2_extracellular_dom	UniProtKB/Swiss-Prot
	GPCR_2_secretin-like	UniProtKB/Swiss-Prot
	GPS	UniProtKB/Swiss-Prot
	TSP1_rpt	UniProtKB/Swiss-Prot
	TSP1_rpt_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:362931	UniProtKB/Swiss-Prot
NCBI Gene	362931	ENTREZGENE
PANTHER	ADHESION G PROTEIN-COUPLED RECEPTOR B1	UniProtKB/Swiss-Prot
	ADHESION G-PROTEIN COUPLED RECEPTOR	UniProtKB/Swiss-Prot
Pfam	7tm_2	UniProtKB/Swiss-Prot
	AGRB_N	UniProtKB/Swiss-Prot
	GAIN	UniProtKB/Swiss-Prot
	GPS	UniProtKB/Swiss-Prot
	HRM	UniProtKB/Swiss-Prot
	TSP_1	UniProtKB/Swiss-Prot
PhenoGen	Adgrb1	PhenoGen
PRINTS	BAIPRECURSOR	UniProtKB/Swiss-Prot
	GPCRSECRETIN	UniProtKB/Swiss-Prot
	TSP1REPEAT	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F2_3	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F2_4	UniProtKB/Swiss-Prot
	GPS	UniProtKB/Swiss-Prot
	TSP1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000029450	RatGTEx
SMART	GPS	UniProtKB/Swiss-Prot
	HormR	UniProtKB/Swiss-Prot
	TSP1	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF82895	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y6L4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZX20_RAT	UniProtKB/TrEMBL
	A0A8I5ZZU7	ENTREZGENE
	A0A8I6ASL1	ENTREZGENE, UniProtKB/TrEMBL
	AGRB1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-03-16	Adgrb1	adhesion G protein-coupled receptor B1	Bai1	brain-specific angiogenesis inhibitor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Bai1	brain-specific angiogenesis inhibitor 1	Bai1_predicted	brain-specific angiogenesis inhibitor 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Bai1_predicted	brain-specific angiogenesis inhibitor 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)