ADGRB1 (adhesion G protein-coupled receptor B1) - Rat Genome Database

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Gene: ADGRB1 (adhesion G protein-coupled receptor B1) Sus scrofa
Analyze
Symbol: ADGRB1
Name: adhesion G protein-coupled receptor B1
RGD ID: 13885237
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); lipopolysaccharide binding (inferred); PDZ domain binding (inferred); INVOLVED IN positive regulation of synapse assembly (ortholog); postsynaptic actin cytoskeleton organization (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); glioblastoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: brain-specific angiogenesis inhibitor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,582,330 - 1,647,573 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,582,321 - 1,658,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ADGRB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,582,330 - 1,647,573 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,582,321 - 1,658,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ADGRB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388142,449,649 - 142,545,007 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8142,449,430 - 142,545,009 (+)EnsemblGRCh38hg38GRCh38
GRCh378143,531,010 - 143,626,368 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,542,379 - 143,623,370 (+)NCBINCBI36Build 36hg18NCBI36
Build 348143,542,378 - 143,623,369NCBI
Celera8139,855,778 - 139,937,685 (+)NCBICelera
Cytogenetic Map8q24.3ENTREZGENE
HuRef8138,802,096 - 138,882,338 (+)NCBIHuRef
CHM1_18143,585,613 - 143,666,276 (+)NCBICHM1_1
T2T-CHM13v2.08143,591,907 - 143,688,308 (+)NCBIT2T-CHM13v2.0
Adgrb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,388,045 - 74,461,314 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,388,044 - 74,461,314 (+)EnsemblGRCm39 Ensembl
GRCm381574,516,196 - 74,589,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,516,195 - 74,589,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371574,346,626 - 74,419,894 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,343,939 - 74,416,478 (+)NCBIMGSCv36mm8
Celera1576,016,847 - 76,094,001 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.22NCBI
Adgrb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,293,681 - 108,365,892 (+)NCBIGRCr8
mRatBN7.27106,404,827 - 106,476,902 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,404,958 - 106,476,902 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,175,524 - 108,234,904 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,397,026 - 110,456,403 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,345,121 - 110,404,495 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07115,766,484 - 115,828,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07115,675,214 - 115,734,250 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47112,622,235 - 112,682,897 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17112,656,235 - 112,717,613 (+)NCBI
Celera7102,819,252 - 102,878,228 (+)NCBICelera
Cytogenetic Map7q34NCBI
Adgrb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554541,237,363 - 1,314,127 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554541,250,261 - 1,313,547 (+)NCBIChiLan1.0ChiLan1.0
ADGRB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27159,880,740 - 159,977,860 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,403,850 - 135,501,242 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,154,065 - 139,251,115 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,221,371 - 142,277,665 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,220,827 - 142,301,070 (+)Ensemblpanpan1.1panPan2
ADGRB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11336,627,791 - 36,649,013 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1336,614,498 - 36,690,936 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,495,752 - 36,557,393 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,023,275 - 37,084,917 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,023,070 - 37,084,917 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11336,742,111 - 36,803,620 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01336,831,945 - 36,893,408 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,253,730 - 37,315,304 (+)NCBIUU_Cfam_GSD_1.0
LOC101964702
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,864,971 - 1,887,131 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364709,248,319 - 9,313,230 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364709,247,749 - 9,313,230 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103237529
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18136,704,318 - 136,784,581 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8136,704,341 - 136,783,991 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660393,266,514 - 3,311,250 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473514,050,213 - 14,113,534 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473514,049,621 - 14,126,287 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ADGRB1
728 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system
High
Medium 1
Low 2 3 2 22
Below cutoff 4 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000039458   ⟹   ENSSSCP00000054635
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,582,330 - 1,646,781 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000074770   ⟹   ENSSSCP00000066412
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,582,330 - 1,646,781 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076993   ⟹   ENSSSCP00000065747
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,583,418 - 1,647,573 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000088362   ⟹   ENSSSCP00000065895
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,582,324 - 1,659,163 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091359   ⟹   ENSSSCP00000064546
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,592,804 - 1,646,781 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091499   ⟹   ENSSSCP00000070871
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl41,635,710 - 1,646,781 (-)Ensembl
RefSeq Acc Id: XM_021088791   ⟹   XP_020944450
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.141,582,321 - 1,658,639 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020944450 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000054635
  ENSSSCP00000054635.2
  ENSSSCP00000064546.1
  ENSSSCP00000065747.1
  ENSSSCP00000066412.1
  ENSSSCP00000070871.1
  ENSSSCP00045044920.1
Reference Protein Sequences
RefSeq Acc Id: XP_020944450   ⟸   XM_021088791
- UniProtKB: A0A8D1J945 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000065895   ⟸   ENSSSCT00000088362
RefSeq Acc Id: ENSSSCP00000054635   ⟸   ENSSSCT00000039458
RefSeq Acc Id: ENSSSCP00000066412   ⟸   ENSSSCT00000074770
RefSeq Acc Id: ENSSSCP00000064546   ⟸   ENSSSCT00000091359
RefSeq Acc Id: ENSSSCP00000070871   ⟸   ENSSSCT00000091499
RefSeq Acc Id: ENSSSCP00000065747   ⟸   ENSSSCT00000076993
Protein Domains
Adhesion G protein-coupled receptor B N-terminal   G-protein coupled receptors family 2 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035891 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00045036726 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039458 ENTREZGENE
  ENSSSCT00000039458.3 UniProtKB/TrEMBL
  ENSSSCT00000074770.2 UniProtKB/TrEMBL
  ENSSSCT00000076993.1 UniProtKB/TrEMBL
  ENSSSCT00000091359.2 UniProtKB/TrEMBL
  ENSSSCT00000091499.2 UniProtKB/TrEMBL
  ENSSSCT00045063651.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.610 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro AGRB_N UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_brain_angio_inhib UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene ADGRB1 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR B1 UniProtKB/TrEMBL
  ADHESION G PROTEIN-COUPLED RECEPTOR B2 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  ISTHMIN-2 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  AGRB_N UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS BAIPRECURSOR UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
  TSP1REPEAT UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF111418 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A287BET6_PIG UniProtKB/TrEMBL
  A0A5G2QQT7_PIG UniProtKB/TrEMBL
  A0A5G2QR73_PIG UniProtKB/TrEMBL
  A0A5G2QUV7_PIG UniProtKB/TrEMBL
  A0A5G2RHL5_PIG UniProtKB/TrEMBL
  A0A8D1J945 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:85120 ENTREZGENE