Otor (otoraplin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Otor (otoraplin) Rattus norvegicus
Analyze
Symbol: Otor
Name: otoraplin
RGD ID: 1305253
Description: Predicted to be involved in cartilage condensation. Predicted to be located in extracellular region. Orthologous to human OTOR (otoraplin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC366206
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83150,868,886 - 150,872,141 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3150,868,886 - 150,872,141 (+)EnsemblGRCr8
mRatBN7.23130,415,339 - 130,418,601 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3130,415,339 - 130,418,601 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3134,321,343 - 134,324,604 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03142,905,383 - 142,908,644 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03140,608,550 - 140,611,812 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03137,154,086 - 137,157,341 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3137,154,086 - 137,157,341 (+)Ensemblrn6Rnor6.0
Rnor_5.03143,596,458 - 143,599,713 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43131,432,572 - 131,435,827 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3129,337,118 - 129,340,373 (+)NCBICelera
RGSC_v3.13131,338,161 - 131,419,405 (+)NCBI
Cytogenetic Map3q41NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10998416  


Genomics

Comparative Map Data
Otor
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83150,868,886 - 150,872,141 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3150,868,886 - 150,872,141 (+)EnsemblGRCr8
mRatBN7.23130,415,339 - 130,418,601 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3130,415,339 - 130,418,601 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3134,321,343 - 134,324,604 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03142,905,383 - 142,908,644 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03140,608,550 - 140,611,812 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03137,154,086 - 137,157,341 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3137,154,086 - 137,157,341 (+)Ensemblrn6Rnor6.0
Rnor_5.03143,596,458 - 143,599,713 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43131,432,572 - 131,435,827 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3129,337,118 - 129,340,373 (+)NCBICelera
RGSC_v3.13131,338,161 - 131,419,405 (+)NCBI
Cytogenetic Map3q41NCBI
OTOR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382016,748,358 - 16,752,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2016,748,358 - 16,770,062 (+)Ensemblhg38GRCh38
GRCh372016,729,003 - 16,732,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362016,677,003 - 16,680,809 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342016,677,002 - 16,680,809NCBI
Celera2016,804,076 - 16,807,889 (+)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2016,691,848 - 16,695,666 (+)NCBIHuRef
CHM1_12016,729,013 - 16,732,824 (+)NCBICHM1_1
T2T-CHM13v2.02016,799,479 - 16,803,287 (+)NCBIT2T-CHM13v2.0
Otor
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392142,920,313 - 142,923,633 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2142,920,393 - 142,923,633 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382143,078,393 - 143,081,713 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2143,078,473 - 143,081,713 (+)Ensemblmm10GRCm38
MGSCv372142,904,228 - 142,907,436 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362142,769,933 - 142,773,141 (+)NCBIMGSCv36mm8
Celera2144,253,506 - 144,256,709 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map270.89NCBI
Otor
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541525,897,320 - 25,901,059 (+)Ensembl
ChiLan1.0NW_00495541525,897,320 - 25,901,059 (+)NCBIChiLan1.0ChiLan1.0
OTOR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,638,719 - 17,642,800 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12017,635,557 - 17,639,638 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02016,708,799 - 16,712,906 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12016,689,253 - 16,692,470 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2016,689,253 - 16,692,470 (+)EnsemblpanPan2panpan1.1
OTOR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1246,095,781 - 6,099,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl246,096,412 - 6,099,285 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha245,962,455 - 5,966,546 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0246,502,291 - 6,506,381 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl246,502,737 - 6,505,834 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,111,419 - 6,115,509 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,207,791 - 6,211,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0246,484,138 - 6,488,229 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Otor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640154,853,952 - 154,857,889 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364853,282,824 - 3,289,128 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364853,285,363 - 3,288,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTOR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11725,380,179 - 25,383,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21728,639,994 - 28,643,375 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTOR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1245,669,511 - 45,677,479 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl245,673,719 - 45,676,435 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660546,056,527 - 6,060,042 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otor
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474117,908,579 - 17,911,354 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474117,904,923 - 17,912,124 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Otor
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15122,561,584 - 122,564,913 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Otor
21 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:39
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000034252
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 2 35 127 69 69 38 73 38 6 240 128 2 113 60 76 31 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000034252   ⟹   ENSRNOP00000033828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3150,868,886 - 150,872,141 (+)Ensembl
mRatBN7.2 Ensembl3130,415,339 - 130,418,601 (+)Ensembl
Rnor_6.0 Ensembl3137,154,086 - 137,157,341 (+)Ensembl
RefSeq Acc Id: NM_001108960   ⟹   NP_001102430
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83150,868,886 - 150,872,141 (+)NCBI
mRatBN7.23130,415,339 - 130,418,601 (+)NCBI
Rnor_6.03137,154,086 - 137,157,341 (+)NCBI
Rnor_5.03143,596,458 - 143,599,713 (+)NCBI
RGSC_v3.43131,432,572 - 131,435,827 (+)RGD
Celera3129,337,118 - 129,340,373 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102430 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL95187 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033828
  ENSRNOP00000033828.5
RefSeq Acc Id: NP_001102430   ⟸   NM_001108960
- Peptide Label: precursor
- UniProtKB: D4A1F5 (UniProtKB/TrEMBL),   A6K732 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033828   ⟸   ENSRNOT00000034252
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1F5-F1-model_v2 AlphaFold D4A1F5 1-128 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305253 AgrOrtholog
BioCyc Gene G2FUF-47632 BioCyc
Ensembl Genes ENSRNOG00000028721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034252 ENTREZGENE
  ENSRNOT00000034252.5 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
InterPro OTOR UniProtKB/TrEMBL
  Otoraplin_SH3 UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report rno:366206 UniProtKB/TrEMBL
NCBI Gene 366206 ENTREZGENE
PANTHER OTORAPLIN UniProtKB/TrEMBL
  PTHR47146 UniProtKB/TrEMBL
Pfam SH3_2 UniProtKB/TrEMBL
PhenoGen Otor PhenoGen
PROSITE SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028721 RatGTEx
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SH3 UniProtKB/TrEMBL
UniProt A6K732 ENTREZGENE, UniProtKB/TrEMBL
  D4A1F5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Otor  otoraplin   Otor_predicted  otoraplin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Otor_predicted  otoraplin (predicted)      Symbol and Name status set to approved 70820 APPROVED