OTOR (otoraplin) - Rat Genome Database

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Gene: OTOR (otoraplin) Canis lupus familiaris
Analyze
Symbol: OTOR
Name: otoraplin
RGD ID: 12187937
Description: INVOLVED IN cartilage condensation (ortholog); ASSOCIATED WITH familial hyperinsulinemic hypoglycemia 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1246,095,781 - 6,099,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl246,096,412 - 6,099,285 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,962,455 - 5,966,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0246,502,291 - 6,506,381 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl246,502,737 - 6,505,834 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,111,419 - 6,115,509 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,207,791 - 6,211,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0246,484,138 - 6,488,229 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OTOR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1246,095,781 - 6,099,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl246,096,412 - 6,099,285 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,962,455 - 5,966,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0246,502,291 - 6,506,381 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl246,502,737 - 6,505,834 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,111,419 - 6,115,509 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,207,791 - 6,211,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0246,484,138 - 6,488,229 (-)NCBIUU_Cfam_GSD_1.0
OTOR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382016,748,358 - 16,752,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2016,748,358 - 16,770,062 (+)EnsemblGRCh38hg38GRCh38
GRCh372016,729,003 - 16,732,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362016,677,003 - 16,680,809 (+)NCBINCBI36Build 36hg18NCBI36
Build 342016,677,002 - 16,680,809NCBI
Celera2016,804,076 - 16,807,889 (+)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2016,691,848 - 16,695,666 (+)NCBIHuRef
CHM1_12016,729,013 - 16,732,824 (+)NCBICHM1_1
T2T-CHM13v2.02016,799,479 - 16,803,287 (+)NCBIT2T-CHM13v2.0
Otor
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392142,920,313 - 142,923,633 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2142,920,393 - 142,923,633 (+)EnsemblGRCm39 Ensembl
GRCm382143,078,393 - 143,081,713 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2143,078,473 - 143,081,713 (+)EnsemblGRCm38mm10GRCm38
MGSCv372142,904,228 - 142,907,436 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362142,769,933 - 142,773,141 (+)NCBIMGSCv36mm8
Celera2144,253,506 - 144,256,709 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map270.89NCBI
Otor
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83150,868,886 - 150,872,141 (+)NCBIGRCr8
mRatBN7.23130,415,339 - 130,418,601 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3130,415,339 - 130,418,601 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3134,321,343 - 134,324,604 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03142,905,383 - 142,908,644 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03140,608,550 - 140,611,812 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03137,154,086 - 137,157,341 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3137,154,086 - 137,157,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03143,596,458 - 143,599,713 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43131,432,572 - 131,435,827 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13131,338,161 - 131,419,405 (+)NCBI
Celera3129,337,118 - 129,340,373 (+)NCBICelera
Cytogenetic Map3q41NCBI
Otor
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541525,897,320 - 25,901,059 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541525,897,320 - 25,901,059 (+)NCBIChiLan1.0ChiLan1.0
OTOR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,638,719 - 17,642,800 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12017,635,557 - 17,639,638 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02016,708,799 - 16,712,906 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12016,689,253 - 16,692,470 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2016,689,253 - 16,692,470 (+)Ensemblpanpan1.1panPan2
Otor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640154,853,952 - 154,857,889 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364853,282,824 - 3,289,128 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364853,285,363 - 3,288,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTOR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11725,380,179 - 25,383,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21728,639,994 - 28,643,375 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTOR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1245,669,511 - 45,677,479 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl245,673,719 - 45,676,435 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660546,056,527 - 6,060,042 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otor
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474117,908,579 - 17,911,354 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474117,904,923 - 17,912,124 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in OTOR
30 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 4 4
Below cutoff 4 5 14 3 6 3 6 3 8 8 10 6

Sequence


RefSeq Acc Id: ENSCAFT00000044148   ⟹   ENSCAFP00000039726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl246,096,412 - 6,099,285 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068789   ⟹   ENSCAFP00000064227
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl246,097,136 - 6,099,285 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034298   ⟹   ENSCAFP00845026847
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl246,502,737 - 6,505,834 (-)Ensembl
RefSeq Acc Id: XM_003639837   ⟹   XP_003639885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1246,096,551 - 6,099,568 (-)NCBI
Dog10K_Boxer_Tasha245,963,460 - 5,966,436 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022409331   ⟹   XP_022265039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1246,095,781 - 6,099,583 (-)NCBI
Dog10K_Boxer_Tasha245,962,455 - 5,966,546 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038432852   ⟹   XP_038288780
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0246,502,291 - 6,506,381 (-)NCBI
RefSeq Acc Id: XM_038432853   ⟹   XP_038288781
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0246,503,296 - 6,506,271 (-)NCBI
RefSeq Acc Id: XM_038509618   ⟹   XP_038365546
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1246,111,419 - 6,115,509 (-)NCBI
RefSeq Acc Id: XM_038509619   ⟹   XP_038365547
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1246,112,424 - 6,115,399 (-)NCBI
RefSeq Acc Id: XM_038571360   ⟹   XP_038427288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0246,484,138 - 6,488,229 (-)NCBI
RefSeq Acc Id: XM_038571361   ⟹   XP_038427289
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0246,485,143 - 6,488,119 (-)NCBI
RefSeq Acc Id: XM_038635555   ⟹   XP_038491483
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0246,207,791 - 6,211,883 (-)NCBI
RefSeq Acc Id: XM_038635557   ⟹   XP_038491485
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0246,208,796 - 6,211,773 (-)NCBI
RefSeq Acc Id: XP_003639885   ⟸   XM_003639837
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LZ94 (UniProtKB/TrEMBL),   A0A8C0RT94 (UniProtKB/TrEMBL),   A0A8I3P5B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022265039   ⟸   XM_022409331
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QJF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000039726   ⟸   ENSCAFT00000044148
RefSeq Acc Id: ENSCAFP00000064227   ⟸   ENSCAFT00000068789
RefSeq Acc Id: XP_038365546   ⟸   XM_038509618
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038365547   ⟸   XM_038509619
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038491483   ⟸   XM_038635555
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038491485   ⟸   XM_038635557
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038288780   ⟸   XM_038432852
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QJF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038288781   ⟸   XM_038432853
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LZ94 (UniProtKB/TrEMBL),   A0A8C0RT94 (UniProtKB/TrEMBL),   A0A8I3P5B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427288   ⟸   XM_038571360
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QJF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427289   ⟸   XM_038571361
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LZ94 (UniProtKB/TrEMBL),   A0A8C0RT94 (UniProtKB/TrEMBL),   A0A8I3P5B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845026847   ⟸   ENSCAFT00845034298
Protein Domains
SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030197 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025137 UniProtKB/TrEMBL
  ENSCAFG00040005029 UniProtKB/TrEMBL
  ENSCAFG00845019434 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000044148.3 UniProtKB/TrEMBL
  ENSCAFT00030046394.1 UniProtKB/TrEMBL
  ENSCAFT00040009437.1 UniProtKB/TrEMBL
  ENSCAFT00040009456.1 UniProtKB/TrEMBL
  ENSCAFT00845034298 ENTREZGENE
  ENSCAFT00845034298.1 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
InterPro OTOR UniProtKB/TrEMBL
  Otoraplin_SH3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report cfa:100856431 UniProtKB/TrEMBL
NCBI Gene OTOR ENTREZGENE
PANTHER OTORAPLIN UniProtKB/TrEMBL
  PTHR47146 UniProtKB/TrEMBL
Pfam SH3_2 UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
UniProt A0A8C0LZ94 ENTREZGENE
  A0A8C0Q3U7_CANLF UniProtKB/TrEMBL
  A0A8C0QJF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RT94 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P5B5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54722 ENTREZGENE