Symbol:
Sfn
Name:
stratifin
RGD ID:
1304729
Description:
Predicted to enable several functions, including identical protein binding activity; phosphoserine residue binding activity; and protein sequestering activity. Predicted to be involved in several processes, including apoptotic signaling pathway; cAMP/PKA signal transduction; and regulation of protein localization. Predicted to act upstream of or within several processes, including keratinocyte differentiation; negative regulation of cell population proliferation; and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in nucleus. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to human SFN (stratifin); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2-acetamidofluorene; 5-aza-2'-deoxycytidine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
14-3-3 protein sigma; LOC313017
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SFN (stratifin) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Sfn (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Sfn (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SFN (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SFN (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Sfn (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SFN (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
SFN (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Sfn (stratifin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SFN (stratifin)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Sfn (stratifin)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ywhaqb (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
ywhaqa (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
14-3-3zeta
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
ftt-2
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
par-5
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 151,110,582 - 151,111,854 (-) NCBI GRCr8 mRatBN7.2 5 145,826,722 - 145,827,994 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 145,826,201 - 145,831,314 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 5 151,823,422 - 151,824,937 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 151,823,887 - 151,824,633 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 5 155,512,802 - 155,514,320 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 151,475,395 - 151,479,996 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 5 151,485,433 - 151,490,434 (+) NCBI Celera 5 144,247,261 - 144,248,776 (-) NCBI Celera Cytogenetic Map 5 q36 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Sfn Rat (+)-Tetrandrine increases expression ISO SFN (Homo sapiens) 6480464 tetrandrine results in increased expression of SFN protein CTD PMID:26822499 Sfn Rat (-)-alpha-phellandrene increases expression ISO Sfn (Mus musculus) 6480464 alpha phellandrene results in increased expression of SFN protein CTD PMID:24861204 Sfn Rat (Z)-3-butylidenephthalide increases expression ISO SFN (Homo sapiens) 6480464 butylidenephthalide results in increased expression of SFN protein CTD PMID:23770345 Sfn Rat 1,2-dimethylhydrazine multiple interactions ISO Sfn (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of SFN mRNA] CTD PMID:22206623 Sfn Rat 1,2-dimethylhydrazine increases expression ISO Sfn (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of SFN mRNA CTD PMID:22206623 Sfn Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of SFN mRNA CTD PMID:30723492 Sfn Rat 17alpha-ethynylestradiol increases expression ISO Sfn (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of SFN mRNA CTD PMID:17555576 and PMID:17942748 Sfn Rat 17alpha-ethynylestradiol multiple interactions ISO Sfn (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFN mRNA CTD PMID:17942748 Sfn Rat 17beta-estradiol increases expression ISO SFN (Homo sapiens) 6480464 Estradiol results in increased expression of SFN mRNA CTD PMID:19167446 Sfn Rat 17beta-estradiol decreases expression ISO SFN (Homo sapiens) 6480464 Estradiol results in decreased expression of SFN mRNA CTD PMID:23019147 and PMID:23094148 Sfn Rat 17beta-estradiol multiple interactions ISO Sfn (Mus musculus) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of SFN mRNA CTD PMID:18556351 Sfn Rat 17beta-estradiol multiple interactions ISO SFN (Homo sapiens) 6480464 [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA and [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein CTD PMID:22534328 Sfn Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Sfn (Mus musculus) 6480464 [3 more ... CTD PMID:23457121 Sfn Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO SFN (Homo sapiens) 6480464 2 more ... CTD PMID:38568856 Sfn Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Sfn (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SFN mRNA CTD PMID:17942748 Sfn Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO SFN (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of SFN mRNA CTD PMID:27913140 Sfn Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Sfn (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of SFN mRNA CTD PMID:21354282 Sfn Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Sfn (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SFN mRNA CTD PMID:19770486 Sfn Rat 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO SFN (Homo sapiens) 6480464 2 more ... CTD PMID:17547211 Sfn Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Sfn (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Sfn Rat 2,6-dimethoxyphenol multiple interactions ISO SFN (Homo sapiens) 6480464 [Sodium Chloride co-treated with pyrogallol 1 more ... CTD PMID:38598786 Sfn Rat 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of SFN mRNA CTD PMID:19167416 and PMID:22213190 Sfn Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Sfn (Mus musculus) 6480464 [3 more ... CTD PMID:23457121 Sfn Rat 4,4'-sulfonyldiphenol increases methylation ISO SFN (Homo sapiens) 6480464 bisphenol S results in increased methylation of SFN promoter CTD PMID:30616060 Sfn Rat 4,4'-sulfonyldiphenol increases expression ISO Sfn (Mus musculus) 6480464 bisphenol S results in increased expression of SFN mRNA CTD PMID:30951980 Sfn Rat 4,4'-sulfonyldiphenol multiple interactions ISO Sfn (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of SFN mRNA CTD PMID:30951980 Sfn Rat 4-nitrophenol decreases expression ISO Sfn (Mus musculus) 6480464 4-nitrophenol results in decreased expression of SFN mRNA CTD PMID:34673133 Sfn Rat 5-(hydroxymethyl)cytosine multiple interactions ISO SFN (Homo sapiens) 6480464 [hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:23940045 Sfn Rat 5-aza-2'-deoxycytidine decreases methylation EXP 6480464 Decitabine results in decreased methylation of SFN promoter CTD PMID:15979784 Sfn Rat 5-aza-2'-deoxycytidine multiple interactions ISO SFN (Homo sapiens) 6480464 [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with Decitabine] results in increased expression of SFN mRNA CTD PMID:22534328 Sfn Rat 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of SFN mRNA CTD PMID:15979784 Sfn Rat 5-aza-2'-deoxycytidine increases expression ISO SFN (Homo sapiens) 6480464 Decitabine results in increased expression of SFN protein CTD PMID:22534328 and PMID:25189999 Sfn Rat 5-fluorouracil multiple interactions ISO SFN (Homo sapiens) 6480464 SFN protein affects the susceptibility to [Fluorouracil co-treated with Cisplatin] more ... CTD PMID:15016801 more ... Sfn Rat 5-fluorouracil increases expression ISO SFN (Homo sapiens) 6480464 Fluorouracil results in increased expression of SFN mRNA CTD PMID:16557594 and PMID:17982676 Sfn Rat 5-fluorouracil affects expression ISO SFN (Homo sapiens) 6480464 Fluorouracil affects the expression of SFN mRNA CTD PMID:16584549 Sfn Rat 5-methylcytosine multiple interactions ISO SFN (Homo sapiens) 6480464 [hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine CTD PMID:23940045 Sfn Rat 6-O-methylguanine multiple interactions ISO SFN (Homo sapiens) 6480464 [O(6)-benzylguanine co-treated with O-(6)-methylguanine] results in decreased expression of SFN mRNA CTD PMID:29666243 Sfn Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SFN mRNA CTD PMID:30047161 Sfn Rat 7,12-dimethyltetraphene increases expression ISO SFN (Homo sapiens) 6480464 9 more ... CTD PMID:21527772 Sfn Rat actinomycin D increases expression ISO SFN (Homo sapiens) 6480464 Dactinomycin results in increased expression of SFN mRNA CTD PMID:21527772 Sfn Rat actinomycin D multiple interactions ISO SFN (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of SFN mRNA and [Dactinomycin co-treated with nutlin 3] results in increased secretion of SFN protein CTD PMID:38460933 Sfn Rat adefovir pivoxil increases expression ISO SFN (Homo sapiens) 6480464 adefovir dipivoxil results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat aflatoxin B1 affects expression ISO SFN (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of SFN protein CTD PMID:20106945 Sfn Rat aflatoxin B1 increases expression ISO SFN (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of SFN mRNA CTD PMID:21527772 more ... Sfn Rat all-trans-retinoic acid multiple interactions ISO Sfn (Mus musculus) 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of SFN mRNA more ... CTD PMID:30951980 and PMID:36189433 Sfn Rat all-trans-retinoic acid decreases expression ISO Sfn (Mus musculus) 6480464 Tretinoin results in decreased expression of SFN mRNA CTD PMID:36189433 Sfn Rat alpha-phellandrene increases expression ISO Sfn (Mus musculus) 6480464 alpha phellandrene results in increased expression of SFN protein CTD PMID:24861204 Sfn Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of SFN mRNA CTD PMID:35163327 Sfn Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of SFN mRNA CTD PMID:30047161 Sfn Rat antirheumatic drug decreases expression ISO SFN (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of SFN mRNA CTD PMID:24449571 Sfn Rat aristolochic acid A increases expression ISO SFN (Homo sapiens) 6480464 aristolochic acid I results in increased expression of SFN mRNA and aristolochic acid I results in increased expression of SFN protein CTD PMID:33212167 Sfn Rat arsane increases expression ISO SFN (Homo sapiens) 6480464 Arsenic results in increased expression of SFN mRNA CTD PMID:19945496 Sfn Rat arsenic atom increases expression ISO SFN (Homo sapiens) 6480464 Arsenic results in increased expression of SFN mRNA CTD PMID:19945496 Sfn Rat arsenous acid decreases response to substance ISO SFN (Homo sapiens) 6480464 SFN protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Sfn Rat azathioprine increases expression ISO SFN (Homo sapiens) 6480464 Azathioprine results in increased expression of SFN mRNA CTD PMID:22623647 Sfn Rat benzalkonium chloride increases expression ISO Sfn (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 Sfn Rat benzene increases expression ISO SFN (Homo sapiens) 6480464 Benzene results in increased expression of SFN mRNA CTD PMID:33064461 Sfn Rat benzo[a]pyrene increases expression ISO SFN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of SFN mRNA CTD PMID:20106945 more ... Sfn Rat benzo[a]pyrene decreases methylation ISO SFN (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of SFN promoter CTD PMID:27901495 Sfn Rat benzo[a]pyrene increases expression ISO Sfn (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of SFN mRNA CTD PMID:19770486 Sfn Rat benzo[a]pyrene increases mutagenesis ISO SFN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of SFN gene CTD PMID:25435355 Sfn Rat Benzo[k]fluoranthene decreases expression ISO Sfn (Mus musculus) 6480464 benzo(k)fluoranthene results in decreased expression of SFN mRNA CTD PMID:26377693 Sfn Rat beta-lapachone increases expression ISO SFN (Homo sapiens) 6480464 beta-lapachone results in increased expression of SFN mRNA CTD PMID:38218311 Sfn Rat beta-naphthoflavone increases expression ISO SFN (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of SFN mRNA CTD PMID:19737606 Sfn Rat bis(2-chloroethyl) sulfide increases alkylation ISO SFN (Homo sapiens) 6480464 Mustard Gas results in increased alkylation of SFN protein CTD PMID:18342354 Sfn Rat bis(2-ethylhexyl) phthalate decreases expression ISO SFN (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of SFN protein CTD PMID:31163220 Sfn Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SFN mRNA CTD PMID:25181051 Sfn Rat bisphenol A increases expression ISO Sfn (Mus musculus) 6480464 bisphenol A results in increased expression of SFN mRNA CTD PMID:32156529 Sfn Rat bisphenol A increases expression ISO SFN (Homo sapiens) 6480464 bisphenol A results in increased expression of SFN protein CTD PMID:37567409 Sfn Rat bisphenol A multiple interactions ISO Sfn (Mus musculus) 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of SFN mRNA CTD PMID:30951980 Sfn Rat bisphenol A affects expression ISO SFN (Homo sapiens) 6480464 bisphenol A affects the expression of SFN mRNA CTD PMID:30903817 Sfn Rat bisphenol A decreases methylation ISO Sfn (Mus musculus) 6480464 bisphenol A results in decreased methylation of SFN promoter CTD PMID:27312807 Sfn Rat bisphenol F multiple interactions ISO Sfn (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of SFN mRNA CTD PMID:30951980 Sfn Rat bisphenol F decreases expression ISO Sfn (Mus musculus) 6480464 bisphenol F results in decreased expression of SFN mRNA CTD PMID:38685157 Sfn Rat bisphenol F increases expression ISO Sfn (Mus musculus) 6480464 bisphenol F results in increased expression of SFN mRNA CTD PMID:30951980 Sfn Rat bortezomib increases expression ISO SFN (Homo sapiens) 6480464 Bortezomib results in increased expression of SFN mRNA CTD PMID:20977926 Sfn Rat bortezomib multiple interactions ISO SFN (Homo sapiens) 6480464 [irinotecan co-treated with Bortezomib] results in decreased expression of SFN protein CTD PMID:16373703 Sfn Rat bucladesine multiple interactions ISO SFN (Homo sapiens) 6480464 [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA and [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein CTD PMID:22534328 Sfn Rat butan-1-ol multiple interactions ISO SFN (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SFN mRNA CTD PMID:29432896 Sfn Rat cadmium atom multiple interactions ISO Sfn (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SFN mRNA CTD PMID:37325564 Sfn Rat cadmium dichloride increases expression ISO SFN (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of SFN mRNA CTD PMID:12160620 more ... Sfn Rat cadmium dichloride multiple interactions ISO Sfn (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SFN mRNA CTD PMID:37325564 Sfn Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SFN mRNA CTD PMID:31077537 Sfn Rat calcitriol increases expression ISO SFN (Homo sapiens) 6480464 Calcitriol results in increased expression of SFN mRNA CTD PMID:26485663 Sfn Rat camptothecin increases expression ISO SFN (Homo sapiens) 6480464 Camptothecin results in increased expression of SFN mRNA CTD PMID:38460933 Sfn Rat cannabidiol increases expression ISO SFN (Homo sapiens) 6480464 Cannabidiol results in increased expression of SFN mRNA CTD PMID:36519830 Sfn Rat carbamazepine affects expression ISO SFN (Homo sapiens) 6480464 Carbamazepine affects the expression of SFN mRNA CTD PMID:25979313 Sfn Rat carbon nanotube affects expression ISO SFN (Homo sapiens) 6480464 Nanotubes and Carbon affects the expression of SFN protein CTD PMID:22001959 Sfn Rat carbon nanotube increases expression ISO Sfn (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Sfn Rat chlorambucil increases expression ISO SFN (Homo sapiens) 6480464 Chlorambucil results in increased expression of SFN mRNA CTD PMID:18092340 Sfn Rat chloroacetaldehyde increases expression ISO SFN (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat chloropicrin decreases expression ISO SFN (Homo sapiens) 6480464 chloropicrin results in decreased expression of SFN mRNA CTD PMID:26352163 Sfn Rat chloroprene increases expression ISO Sfn (Mus musculus) 6480464 Chloroprene results in increased expression of SFN mRNA CTD PMID:23125180 Sfn Rat choline multiple interactions ISO Sfn (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFN mRNA CTD PMID:20938992 Sfn Rat chrysin increases expression ISO SFN (Homo sapiens) 6480464 chrysin results in increased expression of SFN mRNA and chrysin results in increased expression of SFN protein CTD PMID:18331776 Sfn Rat cidofovir anhydrous increases expression ISO SFN (Homo sapiens) 6480464 Cidofovir results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat cisplatin decreases expression ISO SFN (Homo sapiens) 6480464 Cisplatin results in decreased expression of SFN protein CTD PMID:21924258 Sfn Rat cisplatin increases expression ISO SFN (Homo sapiens) 6480464 Cisplatin results in increased expression of SFN mRNA CTD PMID:21532991 more ... Sfn Rat cisplatin affects expression ISO SFN (Homo sapiens) 6480464 Cisplatin affects the expression of SFN mRNA CTD PMID:25450742 Sfn Rat cisplatin affects response to substance ISO SFN (Homo sapiens) 6480464 SFN protein affects the susceptibility to Cisplatin CTD PMID:26894857 Sfn Rat cisplatin multiple interactions ISO SFN (Homo sapiens) 6480464 Cisplatin promotes the reaction [jinfukang results in increased expression of SFN mRNA] more ... CTD PMID:15999354 and PMID:27392435 Sfn Rat clodronic acid increases expression ISO SFN (Homo sapiens) 6480464 Clodronic Acid results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat copper atom increases expression EXP 6480464 Copper results in increased expression of SFN mRNA CTD PMID:22465980 Sfn Rat copper atom multiple interactions ISO SFN (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which affects the expression of SFN mRNA CTD PMID:30911355 Sfn Rat copper atom multiple interactions ISO Sfn (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of SFN mRNA CTD PMID:15467011 Sfn Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of SFN mRNA CTD PMID:22465980 Sfn Rat copper(0) multiple interactions ISO SFN (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which affects the expression of SFN mRNA CTD PMID:30911355 Sfn Rat copper(0) multiple interactions ISO Sfn (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of SFN mRNA CTD PMID:15467011 Sfn Rat copper(II) chloride increases expression ISO SFN (Homo sapiens) 6480464 cupric chloride results in increased expression of SFN mRNA CTD PMID:38568856 Sfn Rat copper(II) sulfate increases expression ISO SFN (Homo sapiens) 6480464 Copper Sulfate results in increased expression of SFN mRNA CTD PMID:19549813 Sfn Rat coumestrol multiple interactions ISO SFN (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SFN mRNA CTD PMID:19167446 Sfn Rat coumestrol increases expression ISO SFN (Homo sapiens) 6480464 Coumestrol results in increased expression of SFN mRNA CTD PMID:19167446 Sfn Rat crocidolite asbestos increases expression ISO SFN (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of SFN protein CTD PMID:29553831 Sfn Rat cyclophosphamide increases expression ISO SFN (Homo sapiens) 6480464 Cyclophosphamide results in increased expression of SFN mRNA CTD PMID:21527772 Sfn Rat cyclosporin A increases expression ISO SFN (Homo sapiens) 6480464 Cyclosporine results in increased expression of SFN mRNA CTD PMID:20106945 more ... Sfn Rat cytarabine decreases response to substance ISO SFN (Homo sapiens) 6480464 SFN protein results in decreased susceptibility to Cytarabine CTD PMID:25189999 Sfn Rat diallyl disulfide multiple interactions EXP 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SFN mRNA CTD PMID:31077537 Sfn Rat diarsenic trioxide decreases response to substance ISO SFN (Homo sapiens) 6480464 SFN protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Sfn Rat Dibutyl phosphate affects expression ISO SFN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of SFN mRNA CTD PMID:37042841 Sfn Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of SFN mRNA CTD PMID:21266533 Sfn Rat diclofenac increases expression ISO SFN (Homo sapiens) 6480464 Diclofenac results in increased expression of SFN mRNA CTD PMID:17379860 Sfn Rat diethylstilbestrol increases expression ISO Sfn (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of SFN mRNA CTD PMID:15171707 and PMID:16636312 Sfn Rat dioxygen increases expression ISO SFN (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat dioxygen multiple interactions ISO Sfn (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SFN mRNA CTD PMID:30529165 Sfn Rat dorsomorphin multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Sfn Rat doxorubicin increases expression ISO SFN (Homo sapiens) 6480464 Doxorubicin results in increased expression of SFN protein CTD PMID:24816189 Sfn Rat doxorubicin affects response to substance ISO SFN (Homo sapiens) 6480464 SFN protein affects the susceptibility to Doxorubicin CTD PMID:26894857 Sfn Rat doxorubicin multiple interactions ISO SFN (Homo sapiens) 6480464 TP53 protein mutant form affects the reaction [Doxorubicin results in decreased expression of SFN mRNA] and TP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of SFN protein] CTD PMID:24816189 Sfn Rat doxorubicin decreases expression ISO SFN (Homo sapiens) 6480464 Doxorubicin results in decreased expression of SFN mRNA CTD PMID:24816189 Sfn Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SFN mRNA CTD PMID:29391264 Sfn Rat Enterolactone multiple interactions ISO SFN (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SFN mRNA CTD PMID:19167446 Sfn Rat entinostat increases expression ISO SFN (Homo sapiens) 6480464 entinostat results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat ethanol multiple interactions ISO SFN (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SFN mRNA CTD PMID:29432896 Sfn Rat Ethyl maltol increases expression ISO SFN (Homo sapiens) 6480464 ethyl maltol results in increased expression of SFN mRNA CTD PMID:37606557 Sfn Rat Ethyl maltol multiple interactions ISO SFN (Homo sapiens) 6480464 APP protein inhibits the reaction [ethyl maltol results in increased expression of SFN mRNA] CTD PMID:37606557 Sfn Rat ethyl methanesulfonate increases expression ISO SFN (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of SFN mRNA CTD PMID:23649840 Sfn Rat etoposide increases expression ISO SFN (Homo sapiens) 6480464 Etoposide results in increased expression of SFN mRNA CTD PMID:21527772 Sfn Rat folic acid multiple interactions ISO Sfn (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFN mRNA more ... CTD PMID:20938992 and PMID:22206623 Sfn Rat formaldehyde increases expression ISO SFN (Homo sapiens) 6480464 Formaldehyde results in increased expression of SFN mRNA CTD PMID:23649840 Sfn Rat furfural multiple interactions ISO SFN (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of SFN protein and [Sodium Chloride co-treated with Furaldehyde] results in increased expression of SFN protein CTD PMID:38598786 Sfn Rat gefitinib decreases expression ISO SFN (Homo sapiens) 6480464 gefitinib results in decreased expression of SFN mRNA CTD PMID:16685379 Sfn Rat gemcitabine affects response to substance ISO SFN (Homo sapiens) 6480464 SFN protein affects the susceptibility to Gemcitabine CTD PMID:26894857 Sfn Rat gemcitabine multiple interactions ISO SFN (Homo sapiens) 6480464 [DNMT1 protein binds to SFN promoter] inhibits the reaction [Gemcitabine results in decreased susceptibility to Gemcitabine] more ... CTD PMID:25189999 and PMID:26894857 Sfn Rat gemcitabine increases methylation ISO SFN (Homo sapiens) 6480464 Gemcitabine results in increased methylation of SFN gene CTD PMID:25189999 Sfn Rat gemcitabine decreases response to substance ISO SFN (Homo sapiens) 6480464 SFN protein results in decreased susceptibility to Gemcitabine CTD PMID:25189999 and PMID:26894857 Sfn Rat GW 4064 increases expression ISO SFN (Homo sapiens) 6480464 GW 4064 results in increased expression of SFN mRNA CTD PMID:31437187 Sfn Rat hydroquinone increases expression ISO SFN (Homo sapiens) 6480464 hydroquinone results in increased expression of SFN mRNA CTD PMID:23940045 Sfn Rat hydroquinone multiple interactions ISO SFN (Homo sapiens) 6480464 [hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine more ... CTD PMID:23940045 Sfn Rat hydroquinone affects methylation ISO SFN (Homo sapiens) 6480464 hydroquinone affects the methylation of SFN promoter CTD PMID:23940045 Sfn Rat ibuprofen increases expression ISO SFN (Homo sapiens) 6480464 Ibuprofen results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat ifosfamide increases expression ISO SFN (Homo sapiens) 6480464 Ifosfamide results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat irinotecan multiple interactions ISO SFN (Homo sapiens) 6480464 [Irinotecan co-treated with Bortezomib] results in decreased expression of SFN protein CTD PMID:16373703 Sfn Rat isobutanol multiple interactions ISO SFN (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SFN mRNA CTD PMID:29432896 Sfn Rat isoniazide decreases expression ISO SFN (Homo sapiens) 6480464 Isoniazid results in decreased expression of SFN mRNA CTD PMID:30008028 Sfn Rat isoprenaline decreases expression ISO SFN (Homo sapiens) 6480464 Isoproterenol results in decreased expression of SFN mRNA CTD PMID:24286936 Sfn Rat ivermectin decreases expression ISO SFN (Homo sapiens) 6480464 Ivermectin results in decreased expression of SFN protein CTD PMID:32959892 Sfn Rat kaempferol increases expression ISO SFN (Homo sapiens) 6480464 kaempferol results in increased expression of SFN mRNA and kaempferol results in increased expression of SFN protein CTD PMID:18331776 Sfn Rat L-methionine multiple interactions ISO Sfn (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SFN mRNA CTD PMID:20938992 Sfn Rat Lasiocarpine increases expression ISO SFN (Homo sapiens) 6480464 lasiocarpine results in increased expression of SFN mRNA CTD PMID:32234424 Sfn Rat lead diacetate decreases expression ISO Sfn (Mus musculus) 6480464 lead acetate results in decreased expression of SFN mRNA CTD PMID:20680508 Sfn Rat lead diacetate increases expression ISO SFN (Homo sapiens) 6480464 lead acetate results in increased expression of SFN mRNA CTD PMID:38568856 Sfn Rat Licochalcone B increases expression ISO SFN (Homo sapiens) 6480464 licochalcone B results in increased expression of SFN mRNA CTD PMID:33647349 Sfn Rat lipopolysaccharide multiple interactions ISO SFN (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of SFN mRNA CTD PMID:35811015 Sfn Rat luteolin increases expression ISO SFN (Homo sapiens) 6480464 Luteolin results in increased expression of SFN mRNA and Luteolin results in increased expression of SFN protein CTD PMID:18331776 Sfn Rat medroxyprogesterone acetate multiple interactions ISO SFN (Homo sapiens) 6480464 [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA and [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein CTD PMID:22534328 Sfn Rat mercury dibromide increases expression ISO SFN (Homo sapiens) 6480464 mercuric bromide results in increased expression of SFN mRNA CTD PMID:26272509 Sfn Rat mercury dibromide multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat metformin increases expression EXP 6480464 Metformin results in increased expression of SFN mRNA CTD PMID:25596134 Sfn Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of SFN mRNA CTD PMID:30047161 Sfn Rat methotrexate increases expression ISO SFN (Homo sapiens) 6480464 Methotrexate results in increased expression of SFN mRNA CTD PMID:17379860 and PMID:21678067 Sfn Rat methyl methanesulfonate increases expression ISO SFN (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of SFN mRNA CTD PMID:21527772 and PMID:23649840 Sfn Rat methylmercury chloride increases expression ISO SFN (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of SFN mRNA CTD PMID:28001369 Sfn Rat mitoxantrone affects response to substance ISO SFN (Homo sapiens) 6480464 SFN protein affects the susceptibility to Mitoxantrone CTD PMID:16217747 Sfn Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Sfn (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SFN mRNA CTD PMID:36189433 Sfn Rat monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of SFN mRNA CTD PMID:28954212 Sfn Rat N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO SFN (Homo sapiens) 6480464 N more ... CTD PMID:18778698 Sfn Rat N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO SFN (Homo sapiens) 6480464 TP53 mutant form inhibits the reaction [N more ... CTD PMID:18778698 Sfn Rat N-methyl-4-phenylpyridinium increases expression ISO Sfn (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SFN protein CTD PMID:26558463 Sfn Rat N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SFN mRNA CTD PMID:28801915 Sfn Rat N-nitrosodiethylamine multiple interactions ISO Sfn (Mus musculus) 6480464 [3 more ... CTD PMID:23457121 Sfn Rat N-nitrosodimethylamine increases expression ISO SFN (Homo sapiens) 6480464 Dimethylnitrosamine results in increased expression of SFN mRNA CTD PMID:17547211 Sfn Rat N-Nitrosopyrrolidine increases expression ISO SFN (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in increased expression of SFN mRNA CTD PMID:32234424 Sfn Rat naphthalene increases expression ISO Sfn (Mus musculus) 6480464 naphthalene results in increased expression of SFN mRNA CTD PMID:18978301 Sfn Rat nickel atom increases expression ISO SFN (Homo sapiens) 6480464 Nickel results in increased expression of SFN mRNA CTD PMID:25583101 Sfn Rat nickel sulfate increases expression ISO Sfn (Mus musculus) 6480464 nickel sulfate results in increased expression of SFN mRNA CTD PMID:16100012 and PMID:16166746 Sfn Rat nitrates multiple interactions ISO Sfn (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of SFN mRNA CTD PMID:35964746 Sfn Rat Nutlin-3 multiple interactions ISO SFN (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of SFN mRNA and [Dactinomycin co-treated with nutlin 3] results in increased secretion of SFN protein CTD PMID:38460933 Sfn Rat obeticholic acid decreases expression ISO SFN (Homo sapiens) 6480464 obeticholic acid results in decreased expression of SFN mRNA CTD PMID:27939613 Sfn Rat ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of SFN mRNA CTD PMID:19237604 Sfn Rat ochratoxin A decreases expression ISO SFN (Homo sapiens) 6480464 ochratoxin A results in decreased expression of SFN mRNA CTD PMID:30008028 and PMID:30559759 Sfn Rat ozone increases expression ISO Sfn (Mus musculus) 6480464 Ozone results in increased expression of SFN mRNA CTD PMID:12763052 more ... Sfn Rat ozone multiple interactions ISO Sfn (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SFN mRNA more ... CTD PMID:25658374 more ... Sfn Rat p-chloromercuribenzoic acid increases expression ISO SFN (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of SFN mRNA CTD PMID:26272509 Sfn Rat p-chloromercuribenzoic acid multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat panobinostat multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat panobinostat increases expression ISO SFN (Homo sapiens) 6480464 panobinostat results in increased expression of SFN mRNA CTD PMID:26272509 Sfn Rat paracetamol decreases expression ISO SFN (Homo sapiens) 6480464 Acetaminophen results in decreased expression of SFN mRNA CTD PMID:21420995 and PMID:29067470 Sfn Rat paracetamol increases expression ISO SFN (Homo sapiens) 6480464 Acetaminophen results in increased expression of SFN mRNA CTD PMID:22230336 Sfn Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of SFN mRNA CTD PMID:32680482 Sfn Rat perfluorohexanesulfonic acid decreases expression ISO Sfn (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of SFN mRNA CTD PMID:37995155 Sfn Rat perfluorononanoic acid decreases expression ISO SFN (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of SFN mRNA CTD PMID:32588087 Sfn Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of SFN mRNA CTD PMID:35163327 Sfn Rat perfluorooctanoic acid decreases expression ISO Sfn (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of SFN protein CTD PMID:36214631 Sfn Rat perfluorooctanoic acid increases expression ISO Sfn (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of SFN protein CTD PMID:37422089 Sfn Rat phenylmercury acetate increases expression ISO SFN (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of SFN mRNA CTD PMID:26272509 Sfn Rat phenylmercury acetate multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat pirinixic acid decreases expression ISO Sfn (Mus musculus) 6480464 pirinixic acid results in decreased expression of SFN mRNA CTD PMID:17426115 Sfn Rat potassium bromate increases expression ISO SFN (Homo sapiens) 6480464 potassium bromate results in increased expression of SFN mRNA CTD PMID:30008028 and PMID:30559759 Sfn Rat progesterone decreases expression ISO Sfn (Mus musculus) 6480464 Progesterone results in decreased expression of SFN mRNA CTD PMID:16966611 Sfn Rat progesterone multiple interactions ISO Sfn (Mus musculus) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of SFN mRNA CTD PMID:18556351 Sfn Rat progesterone increases phosphorylation EXP 6480464 Progesterone results in increased phosphorylation of SFN protein CTD PMID:17303654 Sfn Rat quercetin increases expression ISO SFN (Homo sapiens) 6480464 Quercetin results in increased expression of SFN mRNA and Quercetin results in increased expression of SFN protein CTD PMID:14750173 more ... Sfn Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO SFN (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of SFN mRNA CTD PMID:35811015 Sfn Rat SB 431542 multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Sfn Rat silver atom increases expression ISO Sfn (Mus musculus) 6480464 Silver results in increased expression of SFN mRNA CTD PMID:27131904 Sfn Rat silver(0) increases expression ISO Sfn (Mus musculus) 6480464 Silver results in increased expression of SFN mRNA CTD PMID:27131904 Sfn Rat sodium arsenite decreases expression ISO SFN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of SFN mRNA CTD PMID:12760830 and PMID:38568856 Sfn Rat sodium arsenite increases expression ISO SFN (Homo sapiens) 6480464 sodium arsenite results in increased expression of SFN mRNA CTD PMID:29301061 and PMID:34032870 Sfn Rat sodium chloride multiple interactions ISO SFN (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of SFN protein more ... CTD PMID:38598786 Sfn Rat sodium fluoride increases expression ISO Sfn (Mus musculus) 6480464 Sodium Fluoride results in increased expression of SFN protein CTD PMID:27548804 Sfn Rat sotorasib multiple interactions ISO SFN (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFN mRNA CTD PMID:36139627 Sfn Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of SFN mRNA CTD PMID:30047161 Sfn Rat sulforaphane affects binding ISO SFN (Homo sapiens) 6480464 SFN protein binds to sulforaphane CTD PMID:21838287 Sfn Rat tamoxifen increases expression ISO Sfn (Mus musculus) 6480464 Tamoxifen results in increased expression of SFN mRNA CTD PMID:17555576 Sfn Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SFN mRNA CTD PMID:30723492 Sfn Rat tetraphene decreases expression ISO Sfn (Mus musculus) 6480464 benz(a)anthracene results in decreased expression of SFN mRNA CTD PMID:26377693 Sfn Rat tetrathiomolybdate(2-) decreases expression ISO SFN (Homo sapiens) 6480464 tetrathiomolybdate results in decreased expression of SFN mRNA CTD PMID:37290678 Sfn Rat Theaflavin 3,3'-digallate affects expression ISO SFN (Homo sapiens) 6480464 theaflavin-3 and 3'-digallate affects the expression of SFN mRNA CTD PMID:34925699 Sfn Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SFN mRNA CTD PMID:34492290 Sfn Rat titanium dioxide increases expression ISO Sfn (Mus musculus) 6480464 titanium dioxide results in increased expression of SFN mRNA CTD PMID:27760801 Sfn Rat titanium dioxide increases methylation ISO Sfn (Mus musculus) 6480464 titanium dioxide results in increased methylation of SFN enhancer CTD PMID:35295148 Sfn Rat trametinib multiple interactions ISO SFN (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of SFN mRNA CTD PMID:36139627 Sfn Rat tributylstannane increases expression ISO Sfn (Mus musculus) 6480464 tributyltin results in increased expression of SFN mRNA CTD PMID:31939706 Sfn Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SFN mRNA CTD PMID:33387578 Sfn Rat trichostatin A increases expression ISO SFN (Homo sapiens) 6480464 trichostatin A results in increased expression of SFN mRNA CTD PMID:24935251 and PMID:26272509 Sfn Rat trichostatin A multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat triphenyl phosphate affects expression ISO SFN (Homo sapiens) 6480464 triphenyl phosphate affects the expression of SFN mRNA CTD PMID:37042841 Sfn Rat Triptolide increases expression ISO Sfn (Mus musculus) 6480464 triptolide results in increased expression of SFN mRNA and triptolide results in increased expression of SFN protein CTD PMID:26990902 and PMID:32835833 Sfn Rat urethane decreases expression ISO SFN (Homo sapiens) 6480464 Urethane results in decreased expression of SFN mRNA CTD PMID:28818685 Sfn Rat valproic acid affects expression ISO SFN (Homo sapiens) 6480464 Valproic Acid affects the expression of SFN mRNA CTD PMID:25979313 Sfn Rat valproic acid increases expression ISO SFN (Homo sapiens) 6480464 Valproic Acid results in increased expression of SFN mRNA CTD PMID:23179753 more ... Sfn Rat valproic acid multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat vorinostat multiple interactions ISO SFN (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFN mRNA CTD PMID:27188386 Sfn Rat zinc atom multiple interactions ISO SFN (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SFN mRNA CTD PMID:18593933 Sfn Rat zinc(0) multiple interactions ISO SFN (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SFN mRNA CTD PMID:18593933
Imported Annotations - KEGG (archival)
Imported Annotations - PID (archival)
(+)-Tetrandrine (ISO) (-)-alpha-phellandrene (ISO) (Z)-3-butylidenephthalide (ISO) 1,2-dimethylhydrazine (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (ISO) 17beta-estradiol (ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 2,3-dimethoxynaphthalene-1,4-dione (ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,6-dimethoxyphenol (ISO) 2-acetamidofluorene (EXP) 3,3',4,4',5-pentachlorobiphenyl (ISO) 4,4'-sulfonyldiphenol (ISO) 4-nitrophenol (ISO) 5-(hydroxymethyl)cytosine (ISO) 5-aza-2'-deoxycytidine (EXP,ISO) 5-fluorouracil (ISO) 5-methylcytosine (ISO) 6-O-methylguanine (ISO) 6-propyl-2-thiouracil (EXP) 7,12-dimethyltetraphene (ISO) actinomycin D (ISO) adefovir pivoxil (ISO) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) alpha-phellandrene (ISO) alpha-Zearalanol (EXP) amitrole (EXP) antirheumatic drug (ISO) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) arsenous acid (ISO) azathioprine (ISO) benzalkonium chloride (ISO) benzene (ISO) benzo[a]pyrene (ISO) Benzo[k]fluoranthene (ISO) beta-lapachone (ISO) beta-naphthoflavone (ISO) bis(2-chloroethyl) sulfide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) bortezomib (ISO) bucladesine (ISO) butan-1-ol (ISO) cadmium atom (ISO) cadmium dichloride (EXP,ISO) calcitriol (ISO) camptothecin (ISO) cannabidiol (ISO) carbamazepine (ISO) carbon nanotube (ISO) chlorambucil (ISO) chloroacetaldehyde (ISO) chloropicrin (ISO) chloroprene (ISO) choline (ISO) chrysin (ISO) cidofovir anhydrous (ISO) cisplatin (ISO) clodronic acid (ISO) copper atom (EXP,ISO) copper(0) (EXP,ISO) copper(II) chloride (ISO) copper(II) sulfate (ISO) coumestrol (ISO) crocidolite asbestos (ISO) cyclophosphamide (ISO) cyclosporin A (ISO) cytarabine (ISO) diallyl disulfide (EXP) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) diclofenac (ISO) diethylstilbestrol (ISO) dioxygen (ISO) dorsomorphin (ISO) doxorubicin (ISO) endosulfan (EXP) Enterolactone (ISO) entinostat (ISO) ethanol (ISO) Ethyl maltol (ISO) ethyl methanesulfonate (ISO) etoposide (ISO) folic acid (ISO) formaldehyde (ISO) furfural (ISO) gefitinib (ISO) gemcitabine (ISO) GW 4064 (ISO) hydroquinone (ISO) ibuprofen (ISO) ifosfamide (ISO) irinotecan (ISO) isobutanol (ISO) isoniazide (ISO) isoprenaline (ISO) ivermectin (ISO) kaempferol (ISO) L-methionine (ISO) Lasiocarpine (ISO) lead diacetate (ISO) Licochalcone B (ISO) lipopolysaccharide (ISO) luteolin (ISO) medroxyprogesterone acetate (ISO) mercury dibromide (ISO) metformin (EXP) methimazole (EXP) methotrexate (ISO) methyl methanesulfonate (ISO) methylmercury chloride (ISO) mitoxantrone (ISO) mono(2-ethylhexyl) phthalate (ISO) monosodium L-glutamate (EXP) N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO) N-methyl-4-phenylpyridinium (EXP,ISO) N-nitrosodiethylamine (ISO) N-nitrosodimethylamine (ISO) N-Nitrosopyrrolidine (ISO) naphthalene (ISO) nickel atom (ISO) nickel sulfate (ISO) nitrates (ISO) Nutlin-3 (ISO) obeticholic acid (ISO) ochratoxin A (EXP,ISO) ozone (ISO) p-chloromercuribenzoic acid (ISO) panobinostat (ISO) paracetamol (ISO) paraquat (EXP) perfluorohexanesulfonic acid (ISO) perfluorononanoic acid (ISO) perfluorooctanoic acid (EXP,ISO) phenylmercury acetate (ISO) pirinixic acid (ISO) potassium bromate (ISO) progesterone (EXP,ISO) quercetin (ISO) S-(1,2-dichlorovinyl)-L-cysteine (ISO) SB 431542 (ISO) silver atom (ISO) silver(0) (ISO) sodium arsenite (ISO) sodium chloride (ISO) sodium fluoride (ISO) sotorasib (ISO) sulfadimethoxine (EXP) sulforaphane (ISO) tamoxifen (ISO) tetrachloromethane (EXP) tetraphene (ISO) tetrathiomolybdate(2-) (ISO) Theaflavin 3,3'-digallate (ISO) thioacetamide (EXP) titanium dioxide (ISO) trametinib (ISO) tributylstannane (ISO) trichloroethene (EXP) trichostatin A (ISO) triphenyl phosphate (ISO) Triptolide (ISO) urethane (ISO) valproic acid (ISO) vorinostat (ISO) zinc atom (ISO) zinc(0) (ISO)
Biological Process
biological_process (ND) cAMP/PKA signal transduction (IEA,ISO) establishment of skin barrier (IEA,ISO) intrinsic apoptotic signaling pathway in response to DNA damage (ISO) keratinization (IEA,ISO) keratinocyte development (IEA,ISO) keratinocyte differentiation (IEA,ISO) keratinocyte proliferation (IEA,ISO) negative regulation of innate immune response (ISO) negative regulation of keratinocyte proliferation (IEA,ISO) negative regulation of protein localization to plasma membrane (ISO) negative regulation of stem cell proliferation (IEA,ISO) negative regulation of transcription by RNA polymerase II (IEA,ISO) positive regulation of cell adhesion (ISO) positive regulation of cell growth (IEA,ISO) positive regulation of epidermal cell differentiation (IEA,ISO) positive regulation of protein export from nucleus (IEA,ISO) positive regulation of protein localization (ISO) protein export from nucleus (IEA,ISO) protein localization (IBA) regulation of cell cycle (IEA,ISO) regulation of cell-cell adhesion (ISO) regulation of cyclin-dependent protein serine/threonine kinase activity (ISO) regulation of epidermal cell division (IEA,ISO) regulation of protein localization (ISO) release of cytochrome c from mitochondria (ISO) signal transduction (IBA) skin development (IEA,ISO) stem cell proliferation (IEA,ISO)
1.
Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation.
Akahira J, etal., Clin Cancer Res. 2004 Apr 15;10(8):2687-93.
2.
Coincident inactivation of 14-3-3sigma and p16INK4a is an early event in vulval squamous neoplasia.
Gasco M, etal., Oncogene. 2002 Mar 14;21(12):1876-81.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
5.
Epigenetic and proteolytic inactivation of 14-3-3sigma in breast and prostate cancers.
Horie-Inoue K and Inoue S, Semin Cancer Biol. 2006 Jun;16(3):235-9. Epub 2006 Apr 1.
6.
Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas.
Kunze E, etal., Int J Mol Med. 2006 Oct;18(4):547-57.
7.
Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: molecular signatures of chemoresistant tumors.
L'Esperance S, etal., Int J Oncol. 2006 Jul;29(1):5-24.
8.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
9.
Increasing 14-3-3 sigma expression with declining estrogen receptor alpha and estrogen-responsive finger protein expression defines malignant progression of endometrial carcinoma.
Nakayama H, etal., Pathol Int. 2005 Nov;55(11):707-15.
10.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
11.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12.
GOA pipeline
RGD automated data pipeline
13.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
14.
Comprehensive gene review and curation
RGD comprehensive gene curation
15.
Predicting outcome in minimally invasive (T1a and T1b) urothelial bladder carcinoma using a panel of biomarkers: A high throughput tissue microarray analysis Mhawech-Fauceglia P, Fischer G, Alvarez V Jr, Ahmed A, Herrmann FR, Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute, Buffalo, NY.
See WA Urol Oncol. 2008 May-Jun;26(3):336.
Sfn Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 151,110,582 - 151,111,854 (-) NCBI GRCr8 mRatBN7.2 5 145,826,722 - 145,827,994 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 145,826,201 - 145,831,314 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 5 151,823,422 - 151,824,937 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 151,823,887 - 151,824,633 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 5 155,512,802 - 155,514,320 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 151,475,395 - 151,479,996 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 5 151,485,433 - 151,490,434 (+) NCBI Celera 5 144,247,261 - 144,248,776 (-) NCBI Celera Cytogenetic Map 5 q36 NCBI
SFN Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 26,863,149 - 26,864,456 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 26,863,149 - 26,864,456 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 27,189,640 - 27,190,947 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 27,062,220 - 27,063,534 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 26,873,774 - 26,875,089 NCBI Celera 1 25,586,728 - 25,588,042 (+) NCBI Celera Cytogenetic Map 1 p36.11 NCBI HuRef 1 25,443,317 - 25,444,639 (+) NCBI HuRef CHM1_1 1 27,302,848 - 27,304,162 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 26,701,224 - 26,702,527 (+) NCBI T2T-CHM13v2.0
Sfn Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 4 133,327,867 - 133,329,163 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 4 133,327,867 - 133,329,479 (-) Ensembl GRCm39 Ensembl GRCm38 4 133,600,556 - 133,602,168 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 4 133,600,556 - 133,602,168 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 4 133,156,471 - 133,158,083 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 4 132,872,632 - 132,873,884 (-) NCBI MGSCv36 mm8 Celera 4 131,765,686 - 131,767,298 (-) NCBI Celera Cytogenetic Map 4 D2.3 NCBI cM Map 4 66.25 NCBI
Sfn Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955452 6,217,698 - 6,218,444 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955452 6,217,519 - 6,218,481 (+) NCBI ChiLan1.0 ChiLan1.0
SFN Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 200,004,931 - 200,006,544 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 199,109,040 - 199,110,562 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 26,126,212 - 26,127,761 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 27,182,629 - 27,184,075 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 27,182,834 - 27,183,580 (+) Ensembl panpan1.1 panPan2
SFN Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 2 73,268,289 - 73,269,663 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 2 73,268,791 - 73,269,537 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 2 69,846,343 - 69,847,691 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 2 73,832,085 - 73,833,433 (-) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 2 70,657,031 - 70,658,379 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 2 71,662,570 - 71,663,918 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 2 72,665,732 - 72,667,080 (-) NCBI UU_Cfam_GSD_1.0
Sfn Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405058 45,450,127 - 45,454,645 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936474 11,246,534 - 11,279,433 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936474 11,274,927 - 11,279,427 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
SFN Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 84,188,445 - 84,189,827 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 84,188,521 - 84,189,824 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 77,750,656 - 77,760,032 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
SFN Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 20 105,902,481 - 105,904,313 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 20 105,902,974 - 105,903,720 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666033 10,524,809 - 10,527,364 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Sfn
.
Predicted Target Of
Count of predictions: 166 Count of miRNA genes: 125 Interacting mature miRNAs: 130 Transcripts: ENSRNOT00000005553, ENSRNOT00000043959 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1331796 Thshl2 Thyroid stimulating hormone level QTL 2 2.3 blood thyroid-stimulating hormone amount (VT:0005119) serum thyroid stimulating hormone level (CMO:0001248) 5 102105698 152749382 Rat 10053720 Scort26 Serum corticosterone level QTL 26 2.06 0.0147 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 5 130249266 172190305 Rat 1549845 Scl44 Serum cholesterol level QTL 44 6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 44924861 153890773 Rat 8552960 Pigfal15 Plasma insulin-like growth factor 1 level QTL 15 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 5 116702075 161702075 Rat 1354583 Despr3 Despair related QTL3 4.98 0.0002 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 5 132930505 172190305 Rat 61444 Strs2 Sensitivity to stroke QTL 2 4.7 cerebrum integrity trait (VT:0010549) post-insult time to onset of cerebrovascular lesion (CMO:0002343) 5 141212838 172190305 Rat 1300119 Bp180 Blood pressure QTL 180 3.82 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 5 149642129 171146538 Rat 61452 Ciaa5 CIA Autoantibody QTL 5 3.5 blood autoantibody amount (VT:0003725) calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281) 5 99905133 172190305 Rat 70156 Niddm30 Non-insulin dependent diabetes mellitus QTL 30 3.98 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 5 134369218 156289444 Rat 8552908 Pigfal4 Plasma insulin-like growth factor 1 level QTL 4 6.6 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 5 133789363 172190305 Rat 1331803 Rf32 Renal function QTL 32 2.798 kidney blood vessel physiology trait (VT:0100012) absolute change in renal vascular resistance (CMO:0001900) 5 134369199 172190305 Rat 61393 Bp7 Blood pressure QTL 7 4.5 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 65089051 166764498 Rat 7794791 Mcs33 Mammary carcinoma susceptibility QTL 33 1.93 mammary gland integrity trait (VT:0010552) mammary tumor incidence/prevalence measurement (CMO:0000946) 5 136631198 172190305 Rat 7207486 Bss109 Bone structure and strength QTL 109 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 5 112142946 157142946 Rat 7207481 Bss106 Bone structure and strength QTL 106 7.9 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 5 112142946 157142946 Rat 1302790 Scl20 Serum cholesterol level QTL 20 6.4 0.0001 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 110770739 155770739 Rat 1598861 Cm64 Cardiac mass QTL 64 2.9 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 5 133081618 172190305 Rat 1578766 Tcas11 Tongue tumor susceptibility QTL 11 4.12 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 5 51657967 166600247 Rat 631263 Cm24 Cardiac mass QTL 24 3.5 heart mass (VT:0007028) heart left ventricle weight to body weight ratio (CMO:0000530) 5 149805999 162987697 Rat 631505 Bp103 Blood pressure QTL 103 3.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 138002522 170842766 Rat 1549838 Bss4 Bone structure and strength QTL 4 9.2 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 5 112142946 157142946 Rat 1581505 Rf54 Renal function QTL 54 kidney physiology trait (VT:0002136) kidney 20-HETE level (CMO:0001854) 5 133270647 172190305 Rat 2317753 Glom24 Glomerulus QTL 24 3.1 kidney glomerulus integrity trait (VT:0010546) kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269) 5 141764300 172190305 Rat 8694169 Bw148 Body weight QTL 148 5 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 5 133789363 172190305 Rat 1331721 Bp210 Blood pressure QTL 210 3.413 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 5 148093485 172129029 Rat 1581510 Cm54 Cardiac mass QTL 54 3.4 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 5 125969677 172190305 Rat 1576312 Emca8 Estrogen-induced mammary cancer QTL 8 4.1 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 5 55124766 172190305 Rat 2317056 Wbc3 White blood cell count QTL 3 2.51 0.01 leukocyte quantity (VT:0000217) white blood cell count (CMO:0000027) 5 111236572 156236572 Rat 724525 Bp147 Blood pressure QTL 147 4.3 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 131708216 172190305 Rat 1598847 Cm62 Cardiac mass QTL 62 3.4 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 5 114131300 159131300 Rat 2293642 Bss37 Bone structure and strength QTL 37 4.64 0.0001 femur strength trait (VT:0010010) femur ultimate force (CMO:0001675) 5 125969677 156302135 Rat 2313096 Bmd78 Bone mineral density QTL 78 3.1 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 5 149661912 166600247 Rat 7207488 Bss110 Bone structure and strength QTL 1 8.4 femur strength trait (VT:0010010) femur stiffness (CMO:0001674) 5 112142946 157142946 Rat 8694441 Bw169 Body weight QTL 169 17.61 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 5 116702075 161702075 Rat 7207491 Bss112 Bone structure and strength QTL 112 7 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 5 112142946 157142946 Rat 8694389 Bw160 Body weight QTL 160 6.17 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 5 116702075 161702075 Rat 1354598 Srn6 Serum renin concentration QTL 6 3.8 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 5 74335621 156302135 Rat 8694198 Abfw3 Abdominal fat weight QTL 3 16.13 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 5 116702075 161702075 Rat 1298089 Scl14 Serum cholesterol level QTL 14 5.8 0.0004 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 114131300 159131300 Rat 1598819 Bp292 Blood pressure QTL 292 4.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 133081618 172190305 Rat 1358187 Emca1 Estrogen-induced mammary cancer QTL 1 4.4 mammary gland integrity trait (VT:0010552) post-insult time to mammary tumor formation (CMO:0000345) 5 104262817 153890625 Rat
RH135032
Rat Assembly Chr Position (strand) Source JBrowse Cytogenetic Map 6 q13 UniSTS Cytogenetic Map 5 q36 UniSTS
AW433686
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 5 145,833,256 - 145,833,469 (+) MAPPER mRatBN7.2 Rnor_6.0 5 151,829,957 - 151,830,169 NCBI Rnor6.0 Rnor_5.0 5 155,519,337 - 155,519,549 UniSTS Rnor5.0 RGSC_v3.4 5 151,473,648 - 151,473,860 UniSTS RGSC3.4 Celera 5 144,253,796 - 144,254,008 UniSTS RH 3.4 Map 5 966.11 UniSTS Cytogenetic Map 5 q36 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
8
49
110
86
85
54
25
54
6
210
96
90
45
57
31
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Ensembl Acc Id:
ENSRNOT00000043959 ⟹ ENSRNOP00000040819
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 145,826,201 - 145,831,314 (-) Ensembl Rnor_6.0 Ensembl 5 151,823,887 - 151,824,633 (-) Ensembl
RefSeq Acc Id:
NM_001416777 ⟹ NP_001403706
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 5 151,110,582 - 151,111,854 (-) NCBI mRatBN7.2 5 145,826,722 - 145,827,994 (-) NCBI
Ensembl Acc Id:
ENSRNOP00000040819 ⟸ ENSRNOT00000043959
RefSeq Acc Id:
NP_001403706 ⟸ NM_001416777
- UniProtKB:
G3V9A3 (UniProtKB/TrEMBL), A6ISX9 (UniProtKB/TrEMBL), Q68FS0 (UniProtKB/TrEMBL)
RGD ID: 13694125 Promoter ID: EPDNEW_R4645 Type: single initiation site Name: Sfn_1 Description: stratifin SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 5 151,824,696 - 151,824,756 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2008-04-30
Sfn
stratifin
Sfn_predicted
stratifin (predicted)
'predicted' is removed
2292626 APPROVED
2005-01-12
Sfn_predicted
stratifin (predicted)
Symbol and Name status set to approved
70820 APPROVED
