Actl7a (actin-like 7a) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Actl7a (actin-like 7a) Rattus norvegicus
Analyze
Symbol: Actl7a
Name: actin-like 7a
RGD ID: 1304697
Description: Predicted to enable structural molecule activity. Predicted to be involved in acrosome assembly and fertilization. Part of protein-containing complex. Human ortholog(s) of this gene implicated in male infertility and spermatogenic failure 86. Orthologous to human ACTL7A (actin like 7A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-like protein 7A; Arp7a; LOC298017; T-actin 2; Tact2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8576,242,201 - 76,245,647 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl576,240,427 - 76,247,023 (+)EnsemblGRCr8
mRatBN7.2571,447,447 - 71,450,440 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl571,447,071 - 71,450,908 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx573,336,422 - 73,337,897 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0575,167,856 - 75,169,331 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0575,139,932 - 75,141,407 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd576,290,559 - 76,292,034 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive577,957,152 - 77,958,627 (+)NCBILyon_Normotensive
Lyon_Hypertensive577,179,008 - 77,180,483 (+)NCBILyon_Hypertensive
F344_StmMcwi571,056,063 - 71,057,538 (+)NCBIF344_StmMcwi
Rnor_6.0573,494,582 - 73,498,012 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl573,496,027 - 73,497,609 (+)Ensemblrn6Rnor6.0
Rnor_5.0577,653,984 - 77,655,459 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4574,649,956 - 74,651,431 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera570,303,022 - 70,304,497 (+)NCBICelera
RGSC_v3.1574,655,068 - 74,656,543 (+)NCBI
Cytogenetic Map5q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
acrosomal vesicle  (ISO,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
cytoskeleton  (IEA)
Golgi apparatus  (IEA,ISO,ISS)
male germ cell nucleus  (ISO)
motile cilium  (ISO)
nucleus  (IBA,IEA,ISO,ISS)
perinuclear theca  (ISO)
protein-containing complex  (IDA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cancer-Testis Antigens as New Candidate Diagnostic Biomarkers for Transitional Cell Carcinoma of Bladder. Afsharpad M, etal., Pathol Oncol Res. 2017 Oct 20. pii: 10.1007/s12253-017-0313-4. doi: 10.1007/s12253-017-0313-4.
2. Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A. Boeda B, etal., J Biol Chem. 2011 Apr 1;286(13):11543-54. doi: 10.1074/jbc.M110.171264. Epub 2011 Jan 29.
3. Immune Infertility Should Be Positively Diagnosed Using an Accurate Method by Monitoring the Level of Anti-ACTL7a Antibody. Fu J, etal., Sci Rep. 2016 Mar 9;6:22844. doi: 10.1038/srep22844.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:12672658   PMID:15489334   PMID:21630459  


Genomics

Comparative Map Data
Actl7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8576,242,201 - 76,245,647 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl576,240,427 - 76,247,023 (+)EnsemblGRCr8
mRatBN7.2571,447,447 - 71,450,440 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl571,447,071 - 71,450,908 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx573,336,422 - 73,337,897 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0575,167,856 - 75,169,331 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0575,139,932 - 75,141,407 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd576,290,559 - 76,292,034 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive577,957,152 - 77,958,627 (+)NCBILyon_Normotensive
Lyon_Hypertensive577,179,008 - 77,180,483 (+)NCBILyon_Hypertensive
F344_StmMcwi571,056,063 - 71,057,538 (+)NCBIF344_StmMcwi
Rnor_6.0573,494,582 - 73,498,012 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl573,496,027 - 73,497,609 (+)Ensemblrn6Rnor6.0
Rnor_5.0577,653,984 - 77,655,459 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4574,649,956 - 74,651,431 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera570,303,022 - 70,304,497 (+)NCBICelera
RGSC_v3.1574,655,068 - 74,656,543 (+)NCBI
Cytogenetic Map5q24NCBI
ACTL7A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389108,862,266 - 108,863,756 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9108,862,266 - 108,863,756 (+)Ensemblhg38GRCh38
GRCh379111,624,546 - 111,626,036 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369110,664,424 - 110,665,856 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349108,704,157 - 108,705,590NCBI
Celera982,123,898 - 82,125,330 (+)NCBICelera
Cytogenetic Map9q31.3NCBI
HuRef981,224,355 - 81,225,787 (+)NCBIHuRef
CHM1_19111,771,219 - 111,772,651 (+)NCBICHM1_1
T2T-CHM13v2.09121,031,393 - 121,032,883 (+)NCBIT2T-CHM13v2.0
Actl7a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39456,743,422 - 56,744,925 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl456,743,413 - 56,744,925 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38456,743,422 - 56,744,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl456,743,413 - 56,744,925 (+)Ensemblmm10GRCm38
MGSCv37456,756,294 - 56,757,797 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36456,837,501 - 56,838,971 (+)NCBIMGSCv36mm8
Celera456,651,325 - 56,652,828 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map431.66NCBI
Actl7a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541918,102,980 - 18,106,405 (-)Ensembl
ChiLan1.0NW_00495541918,102,980 - 18,106,405 (-)NCBIChiLan1.0ChiLan1.0
ACTL7A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21130,542,675 - 30,545,968 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1930,545,039 - 30,548,332 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0980,014,898 - 80,016,379 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19108,188,077 - 108,189,597 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9108,188,166 - 108,189,473 (+)EnsemblpanPan2panpan1.1
ACTL7A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11164,031,305 - 64,033,908 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1164,032,358 - 64,033,788 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1162,434,226 - 62,436,139 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01165,166,116 - 65,168,030 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1165,166,603 - 65,167,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11163,687,312 - 63,689,226 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01163,706,106 - 63,708,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01164,399,081 - 64,400,995 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Actl7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947179,279,866 - 179,281,368 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365593,985,327 - 3,986,649 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365593,983,288 - 3,986,932 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTL7A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,883,311 - 249,884,630 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11249,883,247 - 249,884,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21280,413,651 - 280,415,200 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACTL7A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11230,690,891 - 30,692,636 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1230,691,018 - 30,692,325 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603511,991,659 - 11,993,178 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actl7a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247582,650,360 - 2,651,682 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247582,650,235 - 2,651,843 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Actl7a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1194,867,749 - 94,869,222 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Actl7a
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:38
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000022395
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)573779642103472210Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 15 11 110 129 55 54 27 111 23 18 332 256 6 110 38 68 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000022395   ⟹   ENSRNOP00000022395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,240,478 - 76,247,023 (+)Ensembl
mRatBN7.2 Ensembl571,447,071 - 71,450,908 (+)Ensembl
Rnor_6.0 Ensembl573,496,027 - 73,497,609 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146373   ⟹   ENSRNOP00000102903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,240,427 - 76,247,023 (+)Ensembl
RefSeq Acc Id: NM_001011973   ⟹   NP_001011973
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,244,172 - 76,245,647 (+)NCBI
mRatBN7.2571,448,965 - 71,450,440 (+)NCBI
Dahl_SR_JrHsd576,290,559 - 76,292,034 (+)NCBI
Lyon_Normotensive577,957,152 - 77,958,627 (+)NCBI
Lyon_Hypertensive577,179,008 - 77,180,483 (+)NCBI
F344_StmMcwi571,056,063 - 71,057,538 (+)NCBI
Rnor_6.0573,496,075 - 73,497,550 (+)NCBI
Rnor_5.0577,653,984 - 77,655,459 (+)NCBI
RGSC_v3.4574,649,956 - 74,651,431 (+)RGD
Celera570,303,022 - 70,304,497 (+)RGD
Sequence:
RefSeq Acc Id: XM_008763707   ⟹   XP_008761929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,242,648 - 76,245,647 (+)NCBI
mRatBN7.2571,447,447 - 71,450,440 (+)NCBI
Rnor_6.0573,494,582 - 73,498,012 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063287305   ⟹   XP_063143375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,242,201 - 76,245,647 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001011973 (Get FASTA)   NCBI Sequence Viewer  
  XP_008761929 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143375 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH82101 (Get FASTA)   NCBI Sequence Viewer  
  EDL91692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022395.4
  ENSRNOP00000102903
GenBank Protein Q641W9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001011973   ⟸   NM_001011973
- UniProtKB: Q641W9 (UniProtKB/Swiss-Prot),   A6KDR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761929   ⟸   XM_008763707
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000022395   ⟸   ENSRNOT00000022395
RefSeq Acc Id: XP_063143375   ⟸   XM_063287305
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000102903   ⟸   ENSRNOT00000146373
Protein Domains
Actin-like protein 7A N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q641W9-F1-model_v2 AlphaFold Q641W9 1-440 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693751
Promoter ID:EPDNEW_R4276
Type:initiation region
Name:Actl7a_1
Description:actin-like 7a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0573,496,044 - 73,496,104EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304697 AgrOrtholog
BioCyc Gene G2FUF-41221 BioCyc
Ensembl Genes ENSRNOG00000016641 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022395.6 UniProtKB/Swiss-Prot
  ENSRNOT00000146373 ENTREZGENE
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
  Actin, Chain A, domain 4 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134568 IMAGE-MGC_LOAD
InterPro Actin UniProtKB/Swiss-Prot
  ACTL7A_N UniProtKB/Swiss-Prot
  ATPase_NBD UniProtKB/Swiss-Prot
KEGG Report rno:298017 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95295 IMAGE-MGC_LOAD
NCBI Gene 298017 ENTREZGENE
PANTHER PTHR11937 UniProtKB/Swiss-Prot
Pfam Actin UniProtKB/Swiss-Prot
  ACTL7A_N UniProtKB/Swiss-Prot
PhenoGen Actl7a PhenoGen
PRINTS ACTIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016641 RatGTEx
SMART ACTIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot
UniProt A6KDR3 ENTREZGENE, UniProtKB/TrEMBL
  ACL7A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Actl7a  actin-like 7a  Actl7a_predicted  actin-like 7a (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Actl7a_predicted  actin-like 7a (predicted)      Symbol and Name status set to approved 70820 APPROVED