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Gene: Epha1 (Eph receptor A1) Rattus norvegicus

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Symbol:

Epha1

Name:

Eph receptor A1

RGD ID:

1304680

Description:

Predicted to enable fibronectin binding activity; protein kinase binding activity; and transmembrane-ephrin receptor activity. Involved in positive regulation of angiogenesis. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Orthologous to human EPHA1 (EPH receptor A1); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH aflatoxin B1; alpha-Zearalanol; amphetamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ephrin receptor EphA1; ephrin type-A receptor 1; LOC312279

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPHA1 (EPH receptor A1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Epha1 (Eph receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Epha1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EPHA1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPHA1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Epha1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPHA1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPHA1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Epha1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Epha1 (EPH receptor A1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EPHA1 (EPH receptor A1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Epha1 (Eph receptor A1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epha2a (eph receptor A2 a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	epha2b (eph receptor A2 b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	ek1 (eph-like kinase 1)	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	epha4b (eph receptor A4b)	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Eph	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Eph	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER)
Caenorhabditis elegans (roundworm):	vab-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	vab-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	72,213,022 - 72,227,543 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	72,213,037 - 72,227,474 (-)	Ensembl				GRCr8
mRatBN7.2	4	71,246,409 - 71,260,920 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	71,246,409 - 71,260,846 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	76,166,330 - 76,180,773 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	72,079,589 - 72,094,032 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	70,499,006 - 70,513,444 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	71,749,100 - 71,763,681 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	71,749,242 - 71,763,679 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	136,553,640 - 136,568,077 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	70,127,872 - 70,142,309 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	66,176,888 - 66,191,325 (-)	NCBI		Celera
RGSC_v3.1	4	70,404,001 - 70,418,438 (-)	NCBI
Cytogenetic Map	4	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

bladder exstrophy-epispadias-cloacal exstrophy complex (ISO)

Colorectal Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-acetamidofluorene (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

afimoxifene (ISO)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amphetamine (EXP)

antimonite (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

benzopyran (EXP)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bortezomib (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chrysene (ISO)

ciguatoxin CTX1B (ISO)

clofibrate (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

daidzein (ISO)

dioxygen (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

glucose (ISO)

glycitein (ISO)

gold atom (ISO)

gold(0) (ISO)

GSK-J4 (ISO)

indole-3-methanol (EXP)

methapyrilene (ISO)

Monobutylphthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-methyl-N'-nitro-N-nitrosoguanidine (ISO)

okadaic acid (ISO)

oxybenzone (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (ISO)

ponatinib (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (ISO)

rac-lactic acid (ISO)

raloxifene (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

cell adhesion (IEA)

cell surface receptor protein tyrosine kinase signaling pathway (IBA,IEA,ISO)

ephrin receptor signaling pathway (IEA)

negative regulation of cell migration (IEA,ISO)

positive regulation of angiogenesis (IEA,IMP,ISO)

positive regulation of cell migration (IEA,ISO)

positive regulation of cell-matrix adhesion (IEA,ISO)

positive regulation of stress fiber assembly (IEA,ISO,ISS)

substrate adhesion-dependent cell spreading (IEA,ISO)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

receptor complex (IBA)

Molecular Function

ATP binding (IEA)

ephrin receptor activity (IEA,ISO,ISS)

fibronectin binding (IEA,ISO)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein kinase binding (IEA,ISO)

protein tyrosine kinase activity (IEA)

transferase activity (IEA)

transmembrane receptor protein tyrosine kinase activity (IBA,IEA)

transmembrane-ephrin receptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ephrin - ephrin receptor bidirectional signaling axis (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Fibronectin type I repeat is a nonactivating ligand for EphA1 and inhibits ATF3-dependent angiogenesis.	Masuda J, etal., J Biol Chem. 2008 May 9;283(19):13148-55. doi: 10.1074/jbc.M702164200. Epub 2008 Feb 28.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12775584	PMID:19118217	PMID:20043122

Genomics

Comparative Map Data

Epha1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	72,213,022 - 72,227,543 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	72,213,037 - 72,227,474 (-)	Ensembl				GRCr8
mRatBN7.2	4	71,246,409 - 71,260,920 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	71,246,409 - 71,260,846 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	76,166,330 - 76,180,773 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	72,079,589 - 72,094,032 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	70,499,006 - 70,513,444 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	71,749,100 - 71,763,681 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	71,749,242 - 71,763,679 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	136,553,640 - 136,568,077 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	70,127,872 - 70,142,309 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	66,176,888 - 66,191,325 (-)	NCBI		Celera
RGSC_v3.1	4	70,404,001 - 70,418,438 (-)	NCBI
Cytogenetic Map	4	q24	NCBI

EPHA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	143,391,129 - 143,408,856 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	143,390,289 - 143,408,856 (-)	Ensembl			hg38	GRCh38
GRCh37	7	143,088,222 - 143,105,949 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	142,798,327 - 142,816,107 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	142,605,042 - 142,622,822	NCBI
Celera	7	137,925,469 - 137,943,251 (-)	NCBI		Celera
Cytogenetic Map	7	q34-q35	NCBI
HuRef	7	137,425,521 - 137,443,246 (-)	NCBI		HuRef
CHM1_1	7	143,025,132 - 143,041,700 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	144,746,556 - 144,764,287 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	142,490,337 - 142,508,118 (-)	NCBI

Epha1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	42,335,421 - 42,350,249 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	42,335,421 - 42,350,202 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	42,358,487 - 42,373,314 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	42,358,487 - 42,373,268 (-)	Ensembl			mm10	GRCm38
MGSCv37	6	42,308,486 - 42,323,267 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	42,288,094 - 42,302,875 (-)	NCBI		MGSCv36	mm8
Celera	6	42,303,129 - 42,317,914 (-)	NCBI		Celera
Cytogenetic Map	6	B2.1	NCBI
cM Map	6	20.65	NCBI

Epha1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955494	255,162 - 268,777 (+)	Ensembl
ChiLan1.0	NW_004955494	256,008 - 268,777 (+)	NCBI	ChiLan1.0	ChiLan1.0

EPHA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	180,243,561 - 180,261,720 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	32,253,818 - 32,271,977 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	135,385,894 - 135,403,632 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	147,875,028 - 147,892,064 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	147,875,363 - 147,892,745 (-)	Ensembl			panPan2	panpan1.1

EPHA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	6,287,757 - 6,304,082 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	6,287,910 - 6,304,090 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	7,276,373 - 7,292,601 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	6,141,123 - 6,157,305 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	6,141,091 - 6,157,301 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	6,089,005 - 6,105,222 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	5,940,565 - 5,956,781 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	6,015,778 - 6,032,015 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Epha1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	12,055,439 - 12,069,849 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	830,112 - 848,512 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	833,578 - 847,824 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPHA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	6,843,299 - 6,860,989 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	18	6,843,305 - 6,860,976 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	7,081,296 - 7,098,902 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPHA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	112,276,941 - 112,294,505 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	112,277,427 - 112,294,424 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666072	9,023,000 - 9,040,431 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Epha1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624800	11,364,848 - 11,380,725 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624800	11,364,685 - 11,380,725 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Epha1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	97,844,469 - 97,858,643 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Epha1
45 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	135
Count of miRNA genes:	114
Interacting mature miRNAs:	125
Transcripts:	ENSRNOT00000024037
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	39431983	123203361	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	59753119	104753119	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	41400577	86400577	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	44425024	89425024	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58817672	103817672	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58080146	80212111	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	71647492	116647492	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	40471453	75939996	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	41400603	86400603	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	30448961	82336920	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	65060960	127749483	Rat
2317577	Eae24	Experimental allergic encephalomyelitis QTL 24			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	67960112	73752811	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	45429897	149763204	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	51085655	113588029	Rat
2317588	Eae27	Experimental allergic encephalomyelitis QTL 27			nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	69036742	114036742	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	40490442	117737312	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	57613339	151163960	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	57613242	102613242	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	57613242	102613242	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	35113290	80113290	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	57613242	102613242	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	40490442	75726188	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	58079875	82597589	Rat
2306547	Iddm38	Insulin dependent diabetes mellitus QTL 38			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	68353567	113353567	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	59836842	104836842	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	37269577	82269577	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	45429897	149763204	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	61041057	94638356	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63245026	129846354	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	64209744	109209744	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	41400577	86400577	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	57664252	127749483	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	58079875	92690793	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	64084079	109084079	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	63224393	108224393	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	63900458	88813920	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	33538597	116185060	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	59603319	80216952	Rat

Markers in Region

RH141119

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	71,246,091 - 71,246,282 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	71,748,925 - 71,749,115	NCBI	Rnor6.0
Rnor_5.0	4	136,553,323 - 136,553,513	UniSTS	Rnor5.0
RGSC_v3.4	4	70,127,555 - 70,127,745	UniSTS	RGSC3.4
Celera	4	66,176,571 - 66,176,761	UniSTS
RH 3.4 Map	12	176.8	UniSTS
Cytogenetic Map	4	q23	UniSTS

UniSTS:495879

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	71,251,631 - 71,252,258 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	71,754,465 - 71,755,091	NCBI	Rnor6.0
Rnor_5.0	4	136,558,863 - 136,559,489	UniSTS	Rnor5.0
RGSC_v3.4	4	70,133,095 - 70,133,721	UniSTS	RGSC3.4
Celera	4	66,182,111 - 66,182,737	UniSTS
Cytogenetic Map	4	q23	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	67	158	91	90	59	89	59	6	352	188	10	137	81	92	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024037 ⟹ ENSRNOP00000024037

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	72,213,037 - 72,227,474 (-)	Ensembl
mRatBN7.2 Ensembl	4	71,246,409 - 71,260,846 (-)	Ensembl
Rnor_6.0 Ensembl	4	71,749,242 - 71,763,679 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095445 ⟹ ENSRNOP00000088800

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	72,213,037 - 72,227,474 (-)	Ensembl
mRatBN7.2 Ensembl	4	71,246,409 - 71,260,846 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119936 ⟹ ENSRNOP00000092481

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	71,246,409 - 71,260,846 (-)	Ensembl

RefSeq Acc Id:

NM_001107858 ⟹ NP_001101328

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	72,213,037 - 72,227,474 (-)	NCBI
mRatBN7.2	4	71,246,409 - 71,260,846 (-)	NCBI
Rnor_6.0	4	71,749,242 - 71,763,679 (-)	NCBI
Rnor_5.0	4	136,553,640 - 136,568,077 (-)	NCBI
RGSC_v3.4	4	70,127,872 - 70,142,309 (-)	RGD
Celera	4	66,176,888 - 66,191,325 (-)	RGD

Sequence:

show sequence

CAGTCCCTCGCGACCTGGCCCAGCCGTAGGGGCCGTGGTCCCAGGTCCCGGCCGGCGCCATGGA
GCGGCGCTGGCCCCTGGGGCTCGCACTGCTGCTGCTGCTGCTCTGCGCCCCGCTGCCCCCGGGG
GCGCGCGCCGAGGAAGTCACTTTAATGGACACGAGCACAGCACAAGGAGAGTTGGGCTGGCTTC
TGGATCCCCCAGAGACTGGGTGGAGTGAGGTGCAACAAATGCTGAACGGGACACCCCTGTACAT
GTACCAAGACTGCCCAATACAGGAAGGTGGAGATACTGACCACTGGCTTCGCTCCAACTGGATC
TACCGAGGAGAGGAAGCCTCACGTGTCCACGTAGAGCTGCAGTTCACTGTGCGGGACTGTAAAA
GTTTCCCAGGGGGAGCTGGGCCTCTGGGATGCAAAGAGACCTTCAACCTTTTCTACATGGAGAG
TGACCAGGATGTGGGCATTCAACTCCGACGGCCTTTGTTCCAAAAGGTAACAACTGTGGCAGCA
GACCAGAGCTTCACCATCAGAGACCTGGCCTCTGGCTCTGTAAAGCTGAACGTAGAGCACTGCT
CCTTGGGTCACCTCACCCGCCGTGGTCTCTACCTAGCTTTCCACAACCCGGGATCCTGTGTGGC
GCTCGTATCTGTAAGGGTGTTCTACCAGCGCTGCGCAGAGACTGTGCATGGCTTGGCCCACTTC
CCTCACACTCTCCCTGGACCTACAGGGTTGGTAGAAGTAGCTGGAACCTGCCTCTCCCATGCAC
AGATCAGCCTGGGGTCCTCAGGTACACCACGCATGCATTGCAGCCCTGATGGCGAGTGGTTGGT
GCCTGTGGGTCAGTGCCAGTGCGAGCCTGGCTATGAGGAAAGCGGTGGAAGTGTGGGATGCACT
GCCTGTCCTACTGGTTTCTATCGAATGGACATGAATACTCTCCACTGTCTCAAGTGCCCCCAAC
ATAGCGTAGCAGAGTCTGAGGGGTCTACCATCTGTACCTGTGAGAATGGACATTATCGAGCCCC
TGGGGAGGGCCCCCAGGTAGCATGCACGCGTCCCCCATCAGCTCCCCAAAATCTGAGCTTCTCT
GCATCAGGCACTCAGCTCTCCCTACGCTGGGAGCCCCCAAGAGATACAGGGGGACGCCAAGATA
TCAGATACAGTGTGGAATGCTTGCAGTGTCGGGGCATTGCACAGGATGGGGGTCCCTGCCAACC
CTGTGGAAAAGGTGTGCACTTTTCCCCGGCAGCTTCCGGGCTCACCGCATCTACTGTGCAAGTT
GAAGGCCTCGAGCCTTATGCCAACTACACGTTTACCATCAAATCCCAGAACAGAGTGTCGGGAC
TGGACAGTTCCAGCCCTAGCAGCGCTTCTCTCAGTATCAACATGGGGCAAGCAGAGTCACTCTC
TGGCCTGTCACTGAAGCTGGTGAAGAAAGAGCCGAGGCAGCTGGAGCTGACTTGGGCAGGGTCC
CGACTCCAAAACCCTGGGGGGAATCTGAGCTATGAGCTGCACGTGCTGAACCAGGATGAAGAAT
GGCACCAAATGGTGCTGGAACCCAGGGTCTTGCTGACAAAACTTCAGCCAGATACCACATACAT
TGTCAGAGTACGAACACTGACCCCACTGGGGCCTGGCCCTTTCTCCCCTGACCATGAGTTCCGG
ACAAGCCCACCAGTTTCCAGAAGCCTGACTGGAGGAGAGATTGTGGCCATCATCTTTGGATTGC
TGCTTGGAATAGCTCTGCTGATCGGGATTTATGTCTTCCGTTCAAGGAGAGGCCAGCGACAGAG
ACAGCAGAGGCAGCGTGAACGCACCACCAATGTCGATCGAGAGGACAAGCTGTGGCTAAAACCC
TATGTGGACCTCCAGGCCTATGAGGACCCTGCACAGGGAGCCTTAGACTTTGCCCAGGAACTGG
ACCCTGCCTGGCTGATTGTGGACACTGTCATAGGAGAAGGGGAGTTTGGGGAAGTGTATCGGGG
AGCCCTGAGAATCCCCAGCCAAGACTGCAAGACCGTGGCCATTAAGACCTTGAAAGACACATCC
CCAGATGGCTACTGGTGGAATTTCCTTCGAGAAGCAACTATCATGGGCCAGTTCAACCACCCAC
ACATTCTACGCCTAGAAGGTGTCATCACGAAAAGAAAGCCGATCATGATCATCACAGAATTTAT
GGAAAATGGAGCCCTTGATGCCTTTCTGAAGGAACGGGAGGACCAGCTAGTTCCTGGTCAGCTA
GTGGCTATGCTTCTGGGCATAGCATCAGGCATGAACTACCTCAGTGGCCACAATTATGTCCATA
GAGACCTGGCTGCCAGGAACATCTTGGTGAATCAGAACTTGTGCTGCAAGGTATCTGACTTTGG
CCTGACCCGCCTCCTGGATGACTTCGATGGCACCTATGAAACCCAGGGAGGAAAGATCCCTATC
CGTTGGACAGCCCCAGAAGCTATTGCCCATCGGATCTTCACCACAGCCAGTGATGTTTGGAGCT
TTGGGATTGTAATGTGGGAGGTGTTGAGTTTTGGCGACAAACCCTATGGGGAGATGAGCAATCA
AGAGGTAATGAAAAGCATTGAGGATGGGTACCGGCTGCCCCCTCCTGTGGATTGTCCTGCCCCC
CTGTATGAACTCATGAAGAACTGCTGGGCTTACGACCGTGCCCGTCGGCCCCACTTCCTCCAGC
TGCAGGCACATCTGGAACAGCTGCTCACGGACCCCCATTCCCTAAGGACAATTGCCAACTTTGA
CCCTAGGGTGACCCTACGTCTGCCCAGCCTGAGTGGCTCTGATGGGATCCCTTATCGAAGTGTC
TCTGAGTGGCTTGAATCCATACGCATGAAGCGCTACATCCTGCACTTCCGCTCGGCAGGCCTGG
ACACCATGGAGTGTGTGCTGGAGCTGACAGCCGAGGACCTGACGCAGATGGGAATCACATTGCC
AGGGCACCAGAAGCGCATTCTCTGCAGTATTCAAGGATTTAAGGACTGAGCATCCACTGAAAAG
ATGTTCCAGCCCTCTGTCCACTCCCTGGGCCTTTCCTCAGCCTACGAAATGTAGGCTATTGGTG
CTGCTCCTGCCCAGTCAATCAGAACTCTGCCTTTGGACCAAGGAGCCTTTGTTTATAAAGGGGG
TGGGTGGGGTACAAGTGAAGGGGACTGTGGGTGGGTGGGTGCTGGGGGGAGGGTTTAATATATA
TACTTACATATGCATTATCTATTTTTGTAAATAAACAGAGTTGAGTTT

hide sequence

RefSeq Acc Id:

XM_008762883 ⟹ XP_008761105

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	72,213,022 - 72,227,543 (-)	NCBI
mRatBN7.2	4	71,246,512 - 71,260,920 (-)	NCBI
Rnor_6.0	4	71,749,100 - 71,763,681 (-)	NCBI

Sequence:

show sequence

CCCAGTCCCTCGCGACCTGGCCCAGCCGTAGGGGCCGTGGTCCCAGGTCCCGGCCGGCGCCATG
GAGCGGCGCTGGCCCCTGGGGCTCGCACTGCTGCTGCTGCTGCTCTGCGCCCCGCTGCCCCCGG
GGGCGCGCGCCGAGGAAGTCACTTTAATGGACACGAGCACAGCACAAGGAGAGTTGGGCTGGCT
TCTGGATCCCCCAGAGACTGGGTGGAGTGAGGTGCAACAAATGCTGAACGGGACACCCCTGTAC
ATGTACCAAGACTGCCCAATACAGGAAGGTGGAGATACTGACCACTGGCTTCGCTCCAACTGGA
TCTACCGAGGAGAGGAAGCCTCACGTGTCCACGTAGAGCTGCAGTTCACTGTGCGGGACTGTAA
AAGTTTCCCAGGGGGAGCTGGGCCTCTGGGATGCAAAGAGACCTTCAACCTTTTCTACATGGAG
AGTGACCAGGATGTGGGCATTCAACTCCGACGGCCTTTGTTCCAAAAGGTAACAACTGTGGCAG
CAGACCAGAGCTTCACCATCAGAGACCTGGCCTCTGGCTCTGTAAAGCTGAACGTAGAGCACTG
CTCCTTGGGTCACCTCACCCGCCGTGGTCTCTACCTAGCTTTCCACAACCCGGGATCCTGTGTG
GCGCTCGTATCTGTAAGGGTGTTCTACCAGCGCTGCGCAGAGACTGTGCATGGCTTGGCCCACT
TCCCTCACACTCTCCCTGGACCTACAGGGTTGGTAGAAGTAGCTGGAACCTGCCTCTCCCATGC
ACAGATCAGCCTGGGGTCCTCAGGTACACCACGCATGCATTGCAGCCCTGATGGCGAGTGGTTG
GTGCCTGTGGGTCAGTGCCAGTGCGAGCCTGGCTATGAGGAAAGCGGTGGAAGTGTGGGATGCA
CTGCCTGTCCTACTGGTTTCTATCGAATGGACATGAATACTCTCCACTGTCTCAAGTGCCCCCA
ACATAGCGTAGCAGAGTCTGAGGGGTCTACCATCTGTACCTGTGAGAATGGACATTATCGAGCC
CCTGGGGAGGGCCCCCAGGTAGCATGCACGCGTCCCCCATCAGCTCCCCAAAATCTGAGCTTCT
CTGCATCAGGCACTCAGCTCTCCCTACGCTGGGAGCCCCCAAGAGATACAGGGGGACGCCAAGA
TATCAGATACAGTGTGGAATGCTTGCAGTGTCGGGGCATTGCACAGGATGGGGGTCCCTGCCAA
CCCTGTGGAAAAGGTGTGCACTTTTCCCCGGCAGCTTCCGGGCTCACCGCATCTACTGTGCAAG
TTGAAGGCCTCGAGCCTTATGCCAACTACACGTTTACCATCAAATCCCAGAACAGAGTGTCGGG
ACTGGACAGTTCCAGCCCTAGCAGCGCTTCTCTCAGTATCAACATGGGGCAAGCAGAGTCACTC
TCTGGCCTGTCACTGAAGCTGGTGAAGAAAGAGCCGAGGCAGCTGGAGCTGACTTGGGCAGGGT
CCCGACTCCAAAACCCTGGGGGGAATCTGAGCTATGAGCTGCACGTGCTGAACCAGGATGAAGA
ATGGCACCAAATGGTGCTGGAACCCAGGGTCTTGCTGACAAAACTTCAGCCAGATACCACATAC
ATTGTCAGAGTACGAACACTGACCCCACTGGGGCCTGGCCCTTTCTCCCCTGACCATGAGTTCC
GGACAAGCCCACCAGTTTCCAGAAGCCTGACTGGAGGAGAGATTGTGGCCATCATCTTTGGATT
GCTGCTTGGAATAGCTCTGCTGATCGGGATTTATGTCTTCCGTTCAAGGAGAGGCCAGCGACAG
AGACAGCAGAGGCAGCGTGAACGCACCACCAATGTCGATCGAGAGGACAAGCTGTGGCTAAAAC
CCTATGTGGACCTCCAGGCCTATGAGGACCCTGCACAGGGAGCCTTAGACTTTGCCCAGGAACT
GGACCCTGCCTGGCTGATTGTGGACACTGTCATAGGAGAAGGGGAGTTTGGGGAAGTGTATCGG
GGAGCCCTGAGAATCCCCAGCCAAGACTGCAAGACCGTGGCCATTAAGACCTTGAAAGACACAT
CCCCAGATGGCTACTGGTGGAATTTCCTTCGAGAAGCAACTATCATGGGCCAGTTCAACCACCC
ACACATTCTACGCCTAGAAGGTGTCATCACGAAAAGAAAGCCGATCATGATCATCACAGAATTT
ATGGAAAATGGAGCCCTTGATGCCTTTCTGAAGGTGAGGCCGGCAGAGGGTCAGTTCAGGAGGG
GTCACACCTTGGAGTCTCATGTCTCACAGACTTTTCATCCTCTGATATATACATTCGCCCTACT
ACAGGAACGGGAGGACCAGCTAGTTCCTGGTCAGCTAGTGGCTATGCTTCTGGGCATAGCATCA
GGCATGAACTACCTCAGTGGCCACAATTATGTCCATAGAGACCTGGCTGCCAGGAACATCTTGG
TGAATCAGAACTTGTGCTGCAAGGTATCTGACTTTGGCCTGACCCGCCTCCTGGATGACTTCGA
TGGCACCTATGAAACCCAGGGAGGAAAGATCCCTATCCGTTGGACAGCCCCAGAAGCTATTGCC
CATCGGATCTTCACCACAGCCAGTGATGTTTGGAGCTTTGGGATTGTAATGTGGGAGGTGTTGA
GTTTTGGCGACAAACCCTATGGGGAGATGAGCAATCAAGAGGTAATGAAAAGCATTGAGGATGG
GTACCGGCTGCCCCCTCCTGTGGATTGTCCTGCCCCCCTGTATGAACTCATGAAGAACTGCTGG
GCTTACGACCGTGCCCGTCGGCCCCACTTCCTCCAGCTGCAGGCACATCTGGAACAGCTGCTCA
CGGACCCCCATTCCCTAAGGACAATTGCCAACTTTGACCCTAGGGTGACCCTACGTCTGCCCAG
CCTGAGTGGCTCTGATGGGATCCCTTATCGAAGTGTCTCTGAGTGGCTTGAATCCATACGCATG
AAGCGCTACATCCTGCACTTCCGCTCGGCAGGCCTGGACACCATGGAGTGTGTGCTGGAGCTGA
CAGCCGAGGACCTGACGCAGATGGGAATCACATTGCCAGGGCACCAGAAGCGCATTCTCTGCAG
TATTCAAGGATTTAAGGACTGAGCATCCACTGAAAAGATGTTCCAGCCCTCTGTCCACTCCCTG
GGCCTTTCCTCAGCCTACGAAATGTAGGCTATTGGTGCTGCTCCTGCCCAGTCAATCAGAACTC
TGCCTTTGGACCAAGGAGCCTTTGTTTATAAAGGGGGTGGGTGGGGTACAAGTGAAGGGGACTG
TGGGTGGGTGGGTGCTGGGGGGAGGGTTTAATATATATACTTACATATGCATTATCTATTTTTG
TAAATAAACAGAGTTGAGTTTTTATCCCTCCCCTGATCTTTTTCCCCATCAAGACCCTTTATTT
CAACTCCAAGAGTATAGGGTATTATCAAAAAACCAAGTGCTAGCAATTCTGGAAAATGAGGTTT
TATAATCTTAGCTGTGGCCACAACCTAGCAGCACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101328	(Get FASTA)	NCBI Sequence Viewer
	XP_008761105	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM15513	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024037
	ENSRNOP00000024037.3
	ENSRNOP00000088800.1

RefSeq Acc Id:	NP_001101328 ⟸ NM_001107858
- Peptide Label:	precursor
- UniProtKB:	D3ZDH4 (UniProtKB/TrEMBL), A6IF76 (UniProtKB/TrEMBL), A0A8I6AH50 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERRWPLGLALLLLLLCAPLPPGARAEEVTLMDTSTAQGELGWLLDPPETGWSEVQQMLNGTPL YMYQDCPIQEGGDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLFYM ESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLASGSVKLNVEHCSLGHLTRRGLYLAFHNPGSC VALVSVRVFYQRCAETVHGLAHFPHTLPGPTGLVEVAGTCLSHAQISLGSSGTPRMHCSPDGEW LVPVGQCQCEPGYEESGGSVGCTACPTGFYRMDMNTLHCLKCPQHSVAESEGSTICTCENGHYR APGEGPQVACTRPPSAPQNLSFSASGTQLSLRWEPPRDTGGRQDIRYSVECLQCRGIAQDGGPC QPCGKGVHFSPAASGLTASTVQVEGLEPYANYTFTIKSQNRVSGLDSSSPSSASLSINMGQAES LSGLSLKLVKKEPRQLELTWAGSRLQNPGGNLSYELHVLNQDEEWHQMVLEPRVLLTKLQPDTT YIVRVRTLTPLGPGPFSPDHEFRTSPPVSRSLTGGEIVAIIFGLLLGIALLIGIYVFRSRRGQR QRQQRQRERTTNVDREDKLWLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVY RGALRIPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITE FMENGALDAFLKEREDQLVPGQLVAMLLGIASGMNYLSGHNYVHRDLAARNILVNQNLCCKVSD FGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMS NQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLTDPHSLRTIAN FDPRVTLRLPSLSGSDGIPYRSVSEWLESIRMKRYILHFRSAGLDTMECVLELTAEDLTQMGIT LPGHQKRILCSIQGFKD hide sequence

RefSeq Acc Id:	XP_008761105 ⟸ XM_008762883
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AH50 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERRWPLGLALLLLLLCAPLPPGARAEEVTLMDTSTAQGELGWLLDPPETGWSEVQQMLNGTPL YMYQDCPIQEGGDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLFYM ESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLASGSVKLNVEHCSLGHLTRRGLYLAFHNPGSC VALVSVRVFYQRCAETVHGLAHFPHTLPGPTGLVEVAGTCLSHAQISLGSSGTPRMHCSPDGEW LVPVGQCQCEPGYEESGGSVGCTACPTGFYRMDMNTLHCLKCPQHSVAESEGSTICTCENGHYR APGEGPQVACTRPPSAPQNLSFSASGTQLSLRWEPPRDTGGRQDIRYSVECLQCRGIAQDGGPC QPCGKGVHFSPAASGLTASTVQVEGLEPYANYTFTIKSQNRVSGLDSSSPSSASLSINMGQAES LSGLSLKLVKKEPRQLELTWAGSRLQNPGGNLSYELHVLNQDEEWHQMVLEPRVLLTKLQPDTT YIVRVRTLTPLGPGPFSPDHEFRTSPPVSRSLTGGEIVAIIFGLLLGIALLIGIYVFRSRRGQR QRQQRQRERTTNVDREDKLWLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVY RGALRIPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITE FMENGALDAFLKVRPAEGQFRRGHTLESHVSQTFHPLIYTFALLQEREDQLVPGQLVAMLLGIA SGMNYLSGHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAI AHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNC WAYDRARRPHFLQLQAHLEQLLTDPHSLRTIANFDPRVTLRLPSLSGSDGIPYRSVSEWLESIR MKRYILHFRSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD hide sequence

Ensembl Acc Id:

ENSRNOP00000024037 ⟸ ENSRNOT00000024037

Ensembl Acc Id:

ENSRNOP00000088800 ⟸ ENSRNOT00000095445

Ensembl Acc Id:

ENSRNOP00000092481 ⟸ ENSRNOT00000119936

Protein Domains

Eph LBD Fibronectin type-III Protein kinase SAM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZDH4-F1-model_v2	AlphaFold	D3ZDH4	1-977	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693012

Promoter ID:

EPDNEW_R3535

Type:

multiple initiation site

Name:

Epha1_1

Description:

Eph receptor A1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	71,763,678 - 71,763,738	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304680	AgrOrtholog
BioCyc Gene	G2FUF-45086	BioCyc
Ensembl Genes	ENSRNOG00000017525	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024037	ENTREZGENE
	ENSRNOT00000024037.6	UniProtKB/TrEMBL
	ENSRNOT00000095445.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.50	UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/TrEMBL
	ephrin a2 ectodomain	UniProtKB/TrEMBL
	Galactose-binding domain-like	UniProtKB/TrEMBL
	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
	Tumor Necrosis Factor Receptor, subunit A, domain 2	UniProtKB/TrEMBL
InterPro	Eph_TM	UniProtKB/TrEMBL
	EphA1_rcpt_lig-bd	UniProtKB/TrEMBL
	Ephrin_rcpt_lig-bd	UniProtKB/TrEMBL
	Ephrin_rcpt_TKs	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	FN_III	UniProtKB/TrEMBL
	Galactose-bd-like	UniProtKB/TrEMBL
	Growth_fac_rcpt	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	SAM	UniProtKB/TrEMBL
	SAM_type	UniProtKB/TrEMBL
	Ser-Thr/Tyr-Pkinase	UniProtKB/TrEMBL
	Tyr-kin_ephrin_A/B_rcpt-like	UniProtKB/TrEMBL
	Tyr_Pkinase_cat_dom	UniProtKB/TrEMBL
	Tyr_prot_kinase_AS	UniProtKB/TrEMBL
	Tyr_prot_kinase_ephrin_rcpt	UniProtKB/TrEMBL
	Tyr_prot_kinase_rcpt_V_CS	UniProtKB/TrEMBL
KEGG Report	rno:312279	UniProtKB/TrEMBL
NCBI Gene	312279	ENTREZGENE
PANTHER	EPH RECEPTOR A5	UniProtKB/TrEMBL
	RECEPTOR PROTEIN-TYROSINE KINASE	UniProtKB/TrEMBL
Pfam	EphA2_TM	UniProtKB/TrEMBL
	Ephrin_CRD	UniProtKB/TrEMBL
	Ephrin_lbd	UniProtKB/TrEMBL
	fn3	UniProtKB/TrEMBL
	GCC2_GCC3	UniProtKB/TrEMBL
	Pkinase_Tyr	UniProtKB/TrEMBL
	SAM_1	UniProtKB/TrEMBL
PhenoGen	Epha1	PhenoGen
PIRSF	TyrPK_ephrin_receptor	UniProtKB/TrEMBL
PRINTS	TYRKINASE	UniProtKB/TrEMBL
PROSITE	EPH_LBD	UniProtKB/TrEMBL
	FN3	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
	RECEPTOR_TYR_KIN_V_1	UniProtKB/TrEMBL
	RECEPTOR_TYR_KIN_V_2	UniProtKB/TrEMBL
	SAM_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017525	RatGTEx
SMART	EPH_lbd	UniProtKB/TrEMBL
	Ephrin_rec_like	UniProtKB/TrEMBL
	FN3	UniProtKB/TrEMBL
	SAM	UniProtKB/TrEMBL
	TyrKc	UniProtKB/TrEMBL
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
	Gal_bind_like	UniProtKB/TrEMBL
	Grow_fac_recept	UniProtKB/TrEMBL
	Kinase_like	UniProtKB/TrEMBL
	SAM_homology	UniProtKB/TrEMBL
UniProt	A0A8I6AAL3_RAT	UniProtKB/TrEMBL
	A0A8I6AH50	ENTREZGENE
	A6IF76	ENTREZGENE, UniProtKB/TrEMBL
	D3ZDH4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Epha1	Eph receptor A1	Epha1_predicted	Eph receptor A1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Epha1_predicted	Eph receptor A1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)