Gene: EPHA1 (EPH receptor A1)  Homo sapiens

Symbol: EPHA1
Name: EPH receptor A1
Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EPH; EPH tyrosine kinase; eph tyrosine kinase 1; ephrin type-A receptor 1; EPHT; EPHT1; erythropoietin-producing hepatoma amplified sequence; erythropoietin-producing hepatoma receptor; hEpha1; MGC163163; oncogene EPH; OTTHUMP00000208856; soluble EPHA1 variant 1; soluble EPHA1 variant 2; tyrosine-protein kinase receptor EPH
Orthologs: Mus musculus : Epha1 (Eph receptor A1)  MGI
Rattus norvegicus : Epha1 (Eph receptor A1)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_17146,452,029 - 146,468,597-NCBI
Human Alternate Assembly CRA_TCAGchr7v27142,490,337 - 142,508,118-NCBI
Human Genome Assembly HuRef7137,425,521 - 137,443,246-NCBI
Human Genome Assembly GRCh377143,088,205 - 143,105,985-NCBI
Human Genome Assembly Build 367142,798,327 - 142,816,107-NCBI
Human Cytogenetic Map7q34 NCBI
Human Genome Assembly7142,605,042 - 142,622,822 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on EPHA1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1312265
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE