Traf3 (Tnf receptor-associated factor 3) - Rat Genome Database

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Gene: Traf3 (Tnf receptor-associated factor 3) Rattus norvegicus
Analyze
Symbol: Traf3
Name: Tnf receptor-associated factor 3
RGD ID: 1304633
Description: Predicted to enable several functions, including enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in several processes, including regulation of defense response; regulation of macromolecule metabolic process; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within several processes, including antiviral innate immune response; mRNA transcription; and positive regulation of type I interferon production. Predicted to be part of CD40 receptor complex. Predicted to be active in cytoplasmic side of plasma membrane; endosome membrane; and mitochondrion. Human ortholog(s) of this gene implicated in immunodeficiency 132A and immunodeficiency 132B. Orthologous to human TRAF3 (TNF receptor associated factor 3); PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362788
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,025,097 - 136,128,363 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6136,027,157 - 136,128,363 (+)EnsemblGRCr8
mRatBN7.26130,199,696 - 130,307,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,206,484 - 130,305,481 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6130,377,365 - 130,477,985 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,673,357 - 130,773,978 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,035,648 - 130,137,227 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06135,610,698 - 135,720,247 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,610,743 - 135,718,564 (+)Ensemblrn6Rnor6.0
Rnor_5.06144,694,225 - 144,804,047 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46135,925,375 - 136,027,270 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6127,764,032 - 127,864,462 (+)NCBICelera
RGSC_v3.16136,003,658 - 136,028,793 (+)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-taxifolin  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
capsaicin  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
furan  (EXP)
Fusarenone X  (ISO)
glucose  (ISO)
glyphosate  (ISO)
hydroxychloroquine  (ISO)
ibrutinib  (ISO)
isoflurane  (EXP)
lipopolysaccharide  (ISO)
metformin  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
o-anisidine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pentobarbital  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
propiconazole  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triptonide  (ISO)
tungsten  (ISO)
urethane  (EXP)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
VX nerve agent  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11279055   PMID:11728344   PMID:16306937   PMID:17015635   PMID:17158868   PMID:17626074   PMID:20185819   PMID:20614026   PMID:22871113   PMID:23871208   PMID:24803166   PMID:30497068  
PMID:32111144   PMID:33405047   PMID:37000116   PMID:38605440  


Genomics

Comparative Map Data
Traf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,025,097 - 136,128,363 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6136,027,157 - 136,128,363 (+)EnsemblGRCr8
mRatBN7.26130,199,696 - 130,307,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,206,484 - 130,305,481 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6130,377,365 - 130,477,985 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,673,357 - 130,773,978 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,035,648 - 130,137,227 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06135,610,698 - 135,720,247 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,610,743 - 135,718,564 (+)Ensemblrn6Rnor6.0
Rnor_5.06144,694,225 - 144,804,047 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46135,925,375 - 136,027,270 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6127,764,032 - 127,864,462 (+)NCBICelera
RGSC_v3.16136,003,658 - 136,028,793 (+)NCBI
Cytogenetic Map6q32NCBI
TRAF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814102,777,449 - 102,911,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14102,777,326 - 102,911,500 (+)Ensemblhg38GRCh38
GRCh3714103,243,786 - 103,377,837 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614102,313,569 - 102,442,381 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1483,297,948 - 83,426,752 (+)NCBICelera
Cytogenetic Map14q32.32NCBI
HuRef1483,420,470 - 83,553,138 (+)NCBIHuRef
CHM1_114103,181,586 - 103,315,592 (+)NCBICHM1_1
T2T-CHM13v2.01497,013,797 - 97,147,747 (+)NCBIT2T-CHM13v2.0
Traf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,132,799 - 111,233,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,132,804 - 111,233,587 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3812111,166,321 - 111,267,155 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,166,370 - 111,267,153 (+)Ensemblmm10GRCm38
MGSCv3712112,404,759 - 112,505,359 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612111,667,619 - 111,714,956 (+)NCBIMGSCv36mm8
Celera12112,414,118 - 112,461,451 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.94NCBI
Traf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,954,152 - 2,013,367 (+)Ensembl
ChiLan1.0NW_0049555381,954,152 - 2,013,367 (+)NCBIChiLan1.0ChiLan1.0
TRAF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215103,925,240 - 104,063,777 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,141,744 - 103,280,275 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01483,392,689 - 83,530,974 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114103,263,222 - 103,346,383 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14103,263,440 - 103,340,670 (+)EnsemblpanPan2panpan1.1
TRAF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1870,739,389 - 70,794,448 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl870,739,417 - 70,790,645 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha870,191,158 - 70,304,538 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0870,955,838 - 71,067,673 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,955,772 - 71,069,303 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1870,619,852 - 70,733,066 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0870,684,215 - 70,797,522 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,084,379 - 71,197,763 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Traf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,240,015 - 3,351,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835844,727 - 950,664 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936835844,747 - 955,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27128,912,139 - 129,006,560 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRAF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12480,735,234 - 80,872,104 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2480,789,699 - 80,866,480 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605367,926,789 - 68,064,185 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Traf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,728,255 - 1,786,010 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247341,728,353 - 1,820,345 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Traf3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17128,815,397 - 128,840,328 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Traf3
3895 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:532
Count of miRNA genes:238
Interacting mature miRNAs:323
Transcripts:ENSRNOT00000010906
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6131392689143944780Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
D6Rat101  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,245,261 - 130,245,370 (+)MAPPERmRatBN7.2
Rnor_6.06135,658,470 - 135,658,578NCBIRnor6.0
Rnor_5.06144,755,897 - 144,756,005UniSTSRnor5.0
RGSC_v3.46135,964,407 - 135,964,844RGDRGSC3.4
RGSC_v3.46135,964,411 - 135,964,519UniSTSRGSC3.4
Celera6127,802,576 - 127,802,684UniSTS
RGSC_v3.16135,970,598 - 135,970,706RGD
RH 3.4 Map6781.7RGD
RH 3.4 Map6781.7UniSTS
RH 2.0 Map61118.0RGD
SHRSP x BN Map681.7698RGD
Cytogenetic Map6q32UniSTS
AI528849  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,306,850 - 130,306,963 (+)MAPPERmRatBN7.2
Rnor_6.06135,719,934 - 135,720,046NCBIRnor6.0
Rnor_5.06144,694,429 - 144,694,541UniSTSRnor5.0
RGSC_v3.46136,026,957 - 136,027,069UniSTSRGSC3.4
Celera6127,864,149 - 127,864,261UniSTS
Cytogenetic Map6q32UniSTS
BE119065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,264,923 - 130,265,073 (+)MAPPERmRatBN7.2
Rnor_6.06135,678,011 - 135,678,160NCBIRnor6.0
Rnor_5.06144,736,315 - 144,736,464UniSTSRnor5.0
RGSC_v3.46135,984,077 - 135,984,226UniSTSRGSC3.4
Celera6127,822,242 - 127,822,391UniSTS
Cytogenetic Map6q32UniSTS
TRAF3_1584  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,301,628 - 130,302,520 (+)MAPPERmRatBN7.2
Rnor_6.06135,714,712 - 135,715,603NCBIRnor6.0
Rnor_5.06144,698,872 - 144,699,763UniSTSRnor5.0
RGSC_v3.46136,021,735 - 136,022,626UniSTSRGSC3.4
Celera6127,858,939 - 127,859,830UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010906   ⟹   ENSRNOP00000010906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6136,027,601 - 136,128,363 (+)Ensembl
mRatBN7.2 Ensembl6130,206,484 - 130,305,481 (+)Ensembl
Rnor_6.0 Ensembl6135,610,743 - 135,718,564 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077770   ⟹   ENSRNOP00000074381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6136,088,727 - 136,128,363 (+)Ensembl
mRatBN7.2 Ensembl6130,267,645 - 130,305,481 (+)Ensembl
Rnor_6.0 Ensembl6135,680,615 - 135,715,273 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108306   ⟹   ENSRNOP00000094542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6136,088,727 - 136,128,363 (+)Ensembl
mRatBN7.2 Ensembl6130,206,484 - 130,305,481 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127387   ⟹   ENSRNOP00000111538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6136,027,157 - 136,123,896 (+)Ensembl
RefSeq Acc Id: NM_001395112   ⟹   NP_001382041
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,027,049 - 136,128,363 (+)NCBI
mRatBN7.26130,205,848 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112583   ⟹   XP_038968511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,081,013 - 136,128,359 (+)NCBI
mRatBN7.26130,267,323 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112584   ⟹   XP_038968512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,081,013 - 136,128,359 (+)NCBI
mRatBN7.26130,267,320 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112585   ⟹   XP_038968513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,027,045 - 136,128,359 (+)NCBI
mRatBN7.26130,205,836 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112588   ⟹   XP_038968516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,027,860 - 136,128,359 (+)NCBI
mRatBN7.26130,206,657 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112589   ⟹   XP_038968517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,027,331 - 136,128,359 (+)NCBI
mRatBN7.26130,206,133 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112590   ⟹   XP_038968518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,065,618 - 136,128,359 (+)NCBI
mRatBN7.26130,242,840 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112591   ⟹   XP_038968519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,025,097 - 136,128,359 (+)NCBI
mRatBN7.26130,199,696 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_039112592   ⟹   XP_038968520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,060,002 - 136,128,359 (+)NCBI
mRatBN7.26130,238,936 - 130,307,168 (+)NCBI
RefSeq Acc Id: XM_063262147   ⟹   XP_063118217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,065,647 - 136,128,359 (+)NCBI
Ensembl Acc Id: ENSRNOP00000074381   ⟸   ENSRNOT00000077770
Ensembl Acc Id: ENSRNOP00000010906   ⟸   ENSRNOT00000010906
RefSeq Acc Id: XP_038968519   ⟸   XM_039112591
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968513   ⟸   XM_039112585
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968517   ⟸   XM_039112589
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968516   ⟸   XM_039112588
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968520   ⟸   XM_039112592
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968518   ⟸   XM_039112590
- Peptide Label: isoform X3
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968512   ⟸   XM_039112584
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968511   ⟸   XM_039112583
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K7X2 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094542   ⟸   ENSRNOT00000108306
RefSeq Acc Id: NP_001382041   ⟸   NM_001395112
- UniProtKB: D3Z9G0 (UniProtKB/TrEMBL),   A6KBQ0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118217   ⟸   XM_063262147
- Peptide Label: isoform X3
- UniProtKB: A6KBQ0 (UniProtKB/TrEMBL),   D3Z9G0 (UniProtKB/TrEMBL),   A0A8I6ARU4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111538   ⟸   ENSRNOT00000127387
Protein Domains
MATH   RING-type   TRAF-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7X2-F1-model_v2 AlphaFold A0A0G2K7X2 1-610 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304633 AgrOrtholog
BioCyc Gene G2FUF-35855 BioCyc
Ensembl Genes ENSRNOG00000008145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010906 ENTREZGENE
  ENSRNOT00000010906.8 UniProtKB/TrEMBL
  ENSRNOT00000077770 ENTREZGENE
  ENSRNOT00000077770.3 UniProtKB/TrEMBL
  ENSRNOT00000108306 ENTREZGENE
  ENSRNOT00000108306.2 UniProtKB/TrEMBL
  ENSRNOT00000127387 ENTREZGENE
  ENSRNOT00000127387.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A UniProtKB/TrEMBL
InterPro MATH UniProtKB/TrEMBL
  TNF_recpt_TRAF UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
  TRAF3 UniProtKB/TrEMBL
  TRAF3/5_RING UniProtKB/TrEMBL
  TRAF3_MATH UniProtKB/TrEMBL
  TRAF_MEP1_MATH_dom UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
NCBI Gene 362788 ENTREZGENE
PANTHER PTHR10131 UniProtKB/TrEMBL
  PTHR10131:SF76 UniProtKB/TrEMBL
Pfam TRAF-mep_MATH UniProtKB/TrEMBL
  TRAF3_RING UniProtKB/TrEMBL
  zf-TRAF UniProtKB/TrEMBL
PhenoGen Traf3 PhenoGen
PIRSF TRAF UniProtKB/TrEMBL
PROSITE MATH UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008145 RatGTEx
SMART MATH UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
  Trimerization domain of TRAF UniProtKB/TrEMBL
UniProt A0A0G2K7X2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARU4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M0U2_RAT UniProtKB/TrEMBL
  A6KBQ0 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9G0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Traf3  Tnf receptor-associated factor 3   Traf3_predicted  Tnf receptor-associated factor 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Traf3_predicted  Tnf receptor-associated factor 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED