TRAF3 (TNF receptor associated factor 3) - Rat Genome Database

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Gene: TRAF3 (TNF receptor associated factor 3) Sus scrofa
Analyze
Symbol: TRAF3
Name: TNF receptor associated factor 3
RGD ID: 14092107
Description: ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); protein kinase binding (inferred); INVOLVED IN negative regulation of NF-kappaB transcription factor activity (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease axonal type 2O (ortholog); Herpes Simplex Encephalitis (ortholog); Herpes Simplex Encephalitis 3 (ortholog); FOUND IN endosome (ortholog); endosome membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TNF receptor-associated factor 3; TRAF3_TV1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27128,912,139 - 129,006,560 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRAF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27128,912,139 - 129,006,560 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRAF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814102,777,449 - 102,911,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14102,777,449 - 102,911,500 (+)EnsemblGRCh38hg38GRCh38
GRCh3714103,243,786 - 103,377,837 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614102,313,569 - 102,442,381 (+)NCBINCBI36Build 36hg18NCBI36
Celera1483,297,948 - 83,426,752 (+)NCBICelera
Cytogenetic Map14q32.32NCBI
HuRef1483,420,470 - 83,553,138 (+)NCBIHuRef
CHM1_114103,181,586 - 103,315,592 (+)NCBICHM1_1
T2T-CHM13v2.01497,013,797 - 97,147,747 (+)NCBIT2T-CHM13v2.0
Traf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,132,799 - 111,233,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,132,804 - 111,233,587 (+)EnsemblGRCm39 Ensembl
GRCm3812111,166,321 - 111,267,155 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,166,370 - 111,267,153 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712112,404,759 - 112,505,359 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,667,619 - 111,714,956 (+)NCBIMGSCv36mm8
Celera12112,414,118 - 112,461,451 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.94NCBI
Traf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,025,097 - 136,128,363 (+)NCBIGRCr8
mRatBN7.26130,199,696 - 130,307,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,206,484 - 130,305,481 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6130,377,365 - 130,477,985 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,673,357 - 130,773,978 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,035,648 - 130,137,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06135,610,698 - 135,720,247 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,610,743 - 135,718,564 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,694,225 - 144,804,047 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,925,375 - 136,027,270 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16136,003,658 - 136,028,793 (+)NCBI
Celera6127,764,032 - 127,864,462 (+)NCBICelera
Cytogenetic Map6q32NCBI
Traf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,954,152 - 2,013,367 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555381,954,152 - 2,013,367 (+)NCBIChiLan1.0ChiLan1.0
TRAF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215103,925,240 - 104,063,777 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,141,744 - 103,280,275 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01483,392,689 - 83,530,974 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114103,263,222 - 103,346,383 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14103,263,440 - 103,340,670 (+)Ensemblpanpan1.1panPan2
TRAF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1870,739,389 - 70,794,448 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl870,739,417 - 70,790,645 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,191,158 - 70,304,538 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0870,955,838 - 71,067,673 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,955,772 - 71,069,303 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1870,619,852 - 70,733,066 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0870,684,215 - 70,797,522 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,084,379 - 71,197,763 (+)NCBIUU_Cfam_GSD_1.0
Traf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,240,015 - 3,351,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835844,727 - 950,664 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936835844,747 - 955,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12480,735,234 - 80,872,104 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2480,789,699 - 80,866,480 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605367,926,789 - 68,064,185 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Traf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,728,255 - 1,786,010 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247341,728,353 - 1,820,345 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Protein Sequences
Protein RefSeqs XP_005666501 (Get FASTA)   NCBI Sequence Viewer  
  XP_013833875 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937282 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937283 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937284 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937285 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937286 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937287 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937288 (Get FASTA)   NCBI Sequence Viewer  
  XP_020937289 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000028739.4
  ENSSSCP00000029902
  ENSSSCP00000029902.3
  ENSSSCP00000043474
  ENSSSCP00000043474.1
  ENSSSCP00000075413
  ENSSSCP00000075413.1
  ENSSSCP00005023880.1
  ENSSSCP00005023900.1
  ENSSSCP00005023934.1
  ENSSSCP00005023965.1
  ENSSSCP00005023980.1
  ENSSSCP00005023997.1
  ENSSSCP00015006669.1
  ENSSSCP00015006695.1
  ENSSSCP00015006722.1
  ENSSSCP00015006730.1
  ENSSSCP00025013674.1
  ENSSSCP00025013715.1
  ENSSSCP00025013749.1
  ENSSSCP00025013793.1
  ENSSSCP00030023138.1
  ENSSSCP00030023144.1
  ENSSSCP00030023155.1
  ENSSSCP00030023161.1
  ENSSSCP00035031105.1
  ENSSSCP00035031107.1
  ENSSSCP00035031111.1
  ENSSSCP00040047688.1
  ENSSSCP00040047697.1
  ENSSSCP00040047703.1
  ENSSSCP00040047721.1
  ENSSSCP00045012226.1
  ENSSSCP00045012278.1
  ENSSSCP00045012319.1
  ENSSSCP00045012387.1
  ENSSSCP00050038092.1
  ENSSSCP00050038098.1
  ENSSSCP00050038100.1
  ENSSSCP00050038104.1
  ENSSSCP00055033354.1
  ENSSSCP00055033561.1
  ENSSSCP00055033656.1
  ENSSSCP00055033847.1
  ENSSSCP00060006805.1
  ENSSSCP00060006814.1
  ENSSSCP00060006817.1
  ENSSSCP00060006823.1
  ENSSSCP00065016268.1
  ENSSSCP00065016281.1
  ENSSSCP00065016282.1
  ENSSSCP00065016288.1
  ENSSSCP00070018428.1
  ENSSSCP00070018472.1
  ENSSSCP00070018478.1
  ENSSSCP00070018485.1
  ENSSSCP00070018490.1
GenBank Protein JAA53552 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
MATH   RING-type   TRAF-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002525 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024074 UniProtKB/TrEMBL
  ENSSSCG00015012754 UniProtKB/TrEMBL
  ENSSSCG00025024002 UniProtKB/TrEMBL
  ENSSSCG00030036527 UniProtKB/TrEMBL
  ENSSSCG00035056964 UniProtKB/TrEMBL
  ENSSSCG00040075385 UniProtKB/TrEMBL
  ENSSSCG00045010435 UniProtKB/TrEMBL
  ENSSSCG00050065174 UniProtKB/TrEMBL
  ENSSSCG00055021203 UniProtKB/TrEMBL
  ENSSSCG00060013028 UniProtKB/TrEMBL
  ENSSSCG00065028556 UniProtKB/TrEMBL
  ENSSSCG00070011410 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000034635.4 UniProtKB/TrEMBL
  ENSSSCT00000034942 ENTREZGENE
  ENSSSCT00000034942.3 UniProtKB/TrEMBL
  ENSSSCT00000064816 ENTREZGENE
  ENSSSCT00000064816.3 UniProtKB/TrEMBL
  ENSSSCT00000101908 ENTREZGENE
  ENSSSCT00000101908.1 UniProtKB/TrEMBL
  ENSSSCT00005038872.1 UniProtKB/TrEMBL
  ENSSSCT00005038909.1 UniProtKB/TrEMBL
  ENSSSCT00005038964.1 UniProtKB/TrEMBL
  ENSSSCT00005039014.1 UniProtKB/TrEMBL
  ENSSSCT00005039047.1 UniProtKB/TrEMBL
  ENSSSCT00005039076.1 UniProtKB/TrEMBL
  ENSSSCT00015017057.1 UniProtKB/TrEMBL
  ENSSSCT00015017106.1 UniProtKB/TrEMBL
  ENSSSCT00015017176.1 UniProtKB/TrEMBL
  ENSSSCT00015017197.1 UniProtKB/TrEMBL
  ENSSSCT00025032761.1 UniProtKB/TrEMBL
  ENSSSCT00025032861.1 UniProtKB/TrEMBL
  ENSSSCT00025032942.1 UniProtKB/TrEMBL
  ENSSSCT00025033080.1 UniProtKB/TrEMBL
  ENSSSCT00030050877.1 UniProtKB/TrEMBL
  ENSSSCT00030050891.1 UniProtKB/TrEMBL
  ENSSSCT00030050907.1 UniProtKB/TrEMBL
  ENSSSCT00030050918.1 UniProtKB/TrEMBL
  ENSSSCT00035076178.1 UniProtKB/TrEMBL
  ENSSSCT00035076180.1 UniProtKB/TrEMBL
  ENSSSCT00035076185.1 UniProtKB/TrEMBL
  ENSSSCT00040104589.1 UniProtKB/TrEMBL
  ENSSSCT00040104602.1 UniProtKB/TrEMBL
  ENSSSCT00040104610.1 UniProtKB/TrEMBL
  ENSSSCT00040104639.1 UniProtKB/TrEMBL
  ENSSSCT00045017757.1 UniProtKB/TrEMBL
  ENSSSCT00045017829.1 UniProtKB/TrEMBL
  ENSSSCT00045017889.1 UniProtKB/TrEMBL
  ENSSSCT00045017985.1 UniProtKB/TrEMBL
  ENSSSCT00050088780.1 UniProtKB/TrEMBL
  ENSSSCT00050088789.1 UniProtKB/TrEMBL
  ENSSSCT00050088791.1 UniProtKB/TrEMBL
  ENSSSCT00050088795.1 UniProtKB/TrEMBL
  ENSSSCT00055041892.1 UniProtKB/TrEMBL
  ENSSSCT00055042151.1 UniProtKB/TrEMBL
  ENSSSCT00055042270.1 UniProtKB/TrEMBL
  ENSSSCT00055042516.1 UniProtKB/TrEMBL
  ENSSSCT00060017129.1 UniProtKB/TrEMBL
  ENSSSCT00060017147.1 UniProtKB/TrEMBL
  ENSSSCT00060017151.1 UniProtKB/TrEMBL
  ENSSSCT00060017161.1 UniProtKB/TrEMBL
  ENSSSCT00065038534.1 UniProtKB/TrEMBL
  ENSSSCT00065038561.1 UniProtKB/TrEMBL
  ENSSSCT00065038566.1 UniProtKB/TrEMBL
  ENSSSCT00065038580.1 UniProtKB/TrEMBL
  ENSSSCT00070022258.1 UniProtKB/TrEMBL
  ENSSSCT00070022314.1 UniProtKB/TrEMBL
  ENSSSCT00070022318.1 UniProtKB/TrEMBL
  ENSSSCT00070022329.1 UniProtKB/TrEMBL
  ENSSSCT00070022334.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro MATH/TRAF_dom UniProtKB/TrEMBL
  TNF_rcpt--assoc_TRAF UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
  TRAF3 UniProtKB/TrEMBL
  TRAF3/5_RING UniProtKB/TrEMBL
  TRAF3_MATH UniProtKB/TrEMBL
  TRAF_MEP1_MATH_dom UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
KEGG Report ssc:100156979 UniProtKB/TrEMBL
NCBI Gene TRAF3 ENTREZGENE
PANTHER PTHR10131 UniProtKB/TrEMBL
  PTHR10131:SF76 UniProtKB/TrEMBL
Pfam TRAF-mep_MATH UniProtKB/TrEMBL
  TRAF3_RING UniProtKB/TrEMBL
  zf-TRAF UniProtKB/TrEMBL
PIRSF TRAF UniProtKB/TrEMBL
PROSITE MATH UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
SMART MATH UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
  Trimerization domain of TRAF UniProtKB/TrEMBL
UniProt A0A4X1TQG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TQG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TT78_PIG UniProtKB/TrEMBL
  A0A4X1TTD0_PIG UniProtKB/TrEMBL
  A0A4X1TTD5_PIG UniProtKB/TrEMBL
  A0A5K1UKG6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JDD0_PIG UniProtKB/TrEMBL
  A0A8D0JEN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JG63_PIG UniProtKB/TrEMBL
  A0A8D0JI68 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JI78_PIG UniProtKB/TrEMBL
  A0A8D0LNQ4_PIG UniProtKB/TrEMBL
  A0A8D0WLU2_PIG UniProtKB/TrEMBL
  A0A8D0WMA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WPF2_PIG UniProtKB/TrEMBL
  A0A8D1C746 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FAU5_PIG UniProtKB/TrEMBL
  F1SA11 ENTREZGENE, UniProtKB/TrEMBL
  K7GLK8_PIG UniProtKB/TrEMBL
  K9IW74 ENTREZGENE
UniProt Secondary K9IW74 UniProtKB/TrEMBL
VGNC ID VGNC:94360 ENTREZGENE