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Gene: Vwa7 (von Willebrand factor A domain containing 7) Rattus norvegicus

Analyze

Symbol:

Vwa7

Name:

von Willebrand factor A domain containing 7

RGD ID:

1303137

Description:

Predicted to be located in extracellular region. Orthologous to human VWA7 (von Willebrand factor A domain containing 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C6orf27; G7c; NG37; von Willebrand factor A domain-containing protein 7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,799,646 - 3,810,289 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	3,799,646 - 3,810,178 (-)	Ensembl				GRCr8
mRatBN7.2	20	3,794,991 - 3,805,646 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,794,991 - 3,805,525 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	4,494,538 - 4,505,218 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,856,593 - 3,867,275 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,394,498 - 4,405,154 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,008,508 - 5,019,040 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,008,508 - 5,017,669 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	7,081,524 - 7,092,056 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	3,863,665 - 3,874,196 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	4,220,975 - 4,231,506 (+)	NCBI		Celera
RGSC_v3.1	20	3,863,891 - 3,874,423 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (EXP)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium dichloride (EXP,ISO)

cantharidin (ISO)

cisplatin (ISO)

Cuprizon (EXP)

doxorubicin (ISO)

endosulfan (EXP)

glycidol (EXP)

iron dichloride (ISO)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

methimazole (EXP)

Nutlin-3 (ISO)

okadaic acid (ISO)

paracetamol (EXP)

PCB138 (EXP)

perfluorohexanesulfonic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

propiconazole (EXP)

rac-lactic acid (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulforaphane (ISO)

sunitinib (ISO)

thioacetamide (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

tungsten (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

extracellular region (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	G7c, a novel gene in the mouse and human major histocompatibility complex class III region, possibly controlling lung tumor susceptibility.	Snoek M, etal., Immunogenetics 2000 Apr;51(4-5):383-6.

Additional References at PubMed

PMID:9551980	PMID:15060004

Genomics

Comparative Map Data

Vwa7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,799,646 - 3,810,289 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	3,799,646 - 3,810,178 (-)	Ensembl				GRCr8
mRatBN7.2	20	3,794,991 - 3,805,646 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,794,991 - 3,805,525 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	4,494,538 - 4,505,218 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,856,593 - 3,867,275 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,394,498 - 4,405,154 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,008,508 - 5,019,040 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,008,508 - 5,017,669 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	7,081,524 - 7,092,056 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	3,863,665 - 3,874,196 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	4,220,975 - 4,231,506 (+)	NCBI		Celera
RGSC_v3.1	20	3,863,891 - 3,874,423 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

VWA7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,765,590 - 31,777,328 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,765,590 - 31,777,328 (-)	Ensembl			hg38	GRCh38
GRCh37	6	31,733,367 - 31,745,105 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,841,350 - 31,853,087 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	31,841,494 - 31,852,535	NCBI
Celera	6	33,331,616 - 33,343,354 (-)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,519,785 - 31,531,513 (-)	NCBI		HuRef
CHM1_1	6	31,735,494 - 31,747,244 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,618,637 - 31,630,375 (-)	NCBI		T2T-CHM13v2.0

Vwa7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,235,388 - 35,245,717 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,235,555 - 35,245,717 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	35,016,360 - 35,026,741 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,016,579 - 35,026,741 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	35,153,524 - 35,163,686 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,624,635 - 34,634,797 (+)	NCBI		MGSCv36	mm8
Celera	17	38,112,805 - 38,122,972 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.55	NCBI

Vwa7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	300,753 - 309,823 (-)	Ensembl
ChiLan1.0	NW_004955437	299,554 - 308,609 (-)	NCBI	ChiLan1.0	ChiLan1.0

VWA7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,241,865 - 46,254,429 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,204,106 - 42,215,878 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,426,502 - 31,438,564 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,313,967 - 32,325,738 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,313,967 - 32,325,738 (-)	Ensembl			panPan2	panpan1.1

VWA7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,246,055 - 1,254,829 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,245,105 - 1,254,272 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,381,656 - 1,391,335 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,388,384 - 1,398,073 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,388,283 - 1,398,036 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,247,608 - 1,257,294 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,314,770 - 1,324,458 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,382,700 - 1,392,375 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Vwa7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,786,498 - 35,795,692 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,766,380 - 1,774,937 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,765,689 - 1,774,937 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VWA7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,874,899 - 23,885,994 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	23,874,900 - 23,885,551 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

VWA7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,245,460 - 40,258,324 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,246,105 - 40,258,125 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	31,677,689 - 31,690,683 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vwa7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,442,721 - 24,451,635 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	24,442,327 - 24,451,739 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Vwa7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	7,616,463 - 7,625,314 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Vwa7
168 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	574
Count of miRNA genes:	256
Interacting mature miRNAs:	314
Transcripts:	ENSRNOT00000001153
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1533200	5306452	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	1	6693431	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26128279	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3626323	10078622	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	6693431	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3626323	9244918	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

RH129081

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,795,579 - 3,795,742 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,018,289 - 5,018,451	NCBI	Rnor6.0
Rnor_5.0	20	7,091,305 - 7,091,467	UniSTS	Rnor5.0
RGSC_v3.4	20	3,864,254 - 3,864,416	UniSTS	RGSC3.4
Celera	20	4,230,755 - 4,230,917	UniSTS
RH 3.4 Map	20	52.22	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH134540

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	3,805,787 - 3,806,488 (-)	MAPPER	mRatBN7.2
Rnor_6.0	20	5,007,545 - 5,008,245	NCBI	Rnor6.0
Rnor_5.0	20	7,080,561 - 7,081,261	UniSTS	Rnor5.0
RGSC_v3.4	20	3,874,459 - 3,875,159	UniSTS	RGSC3.4
Celera	20	4,220,012 - 4,220,712	UniSTS
RH 3.4 Map	20	52.52	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	86	85	54	79	54	6	338	179	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_212499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010060676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001153 ⟹ ENSRNOP00000001153

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	3,799,646 - 3,810,178 (-)	Ensembl
mRatBN7.2 Ensembl	20	3,794,991 - 3,805,525 (-)	Ensembl
Rnor_6.0 Ensembl	20	5,008,508 - 5,017,669 (+)	Ensembl

RefSeq Acc Id:

NM_212499 ⟹ NP_997664

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,799,646 - 3,810,178 (-)	NCBI
mRatBN7.2	20	3,794,991 - 3,805,525 (-)	NCBI
Rnor_6.0	20	5,008,508 - 5,019,040 (+)	NCBI
Rnor_5.0	20	7,081,524 - 7,092,056 (+)	NCBI
RGSC_v3.4	20	3,863,665 - 3,874,196 (-)	RGD
Celera	20	4,220,975 - 4,231,506 (+)	RGD

Sequence:

show sequence

CCTGGCTTTCGCTACATCGTGTGGCCCTGGGTTGGCATGAATGGAAGAGGGCCAGGGGCTGCCT
GTCCTCAACCCCTTGCTAAGAGCCTCCCTCTCATGCTACTGAGGCCCAGTTAATTATAGCTCTG
ACCTAAGTGCCCTGTGACGCCACACCCGGGCCAGCACTGCCCAGGAGACCCAGCAACCAGGTCC
ATGTTTCAGCCATGCTCCCTGTGGAGGTCCCCCTGTCCCAGCTGGGCCCCCCAGTACTGCTGCT
CCAGCTGCTGTTGCCCCCAACATCTGCCTTCTTTCCCAACATCTGGAGCCTTCTGGCTGCCCCT
GGCTCCATCACTCACCAAGACCTGACTGAAGAGGCTGCACTCAATGTCACCCTTGAGCTCTTTC
TGGAACAGCCACCCCCAGGCCGACCGCACCTCCATCTAGAGGACTACAGGGGCCGGACCCTCCT
CGCCGATGATATCTTTGCTGCCTACTTTGGATCAGGGTTTTCTTCCCGGAGGTTCAGAGCGGCT
TTAGGAGAGGTGTCTCGTGCCAATGCAGCCCAAGACTTCCTGCCAGCTTCCAAGAGCAACCCCG
ACCTGCACTTCGATGCTGAACGGCTGGTCCAGGGGCGCACTCGCCTGGAGGGGGCCCTTCGGGA
AACCCTGGTGGCCGCCAGAGCACTAGAGTATACACTGGCCCGACAGCGTCTCGGGGCTGCACTC
CATGCCCTGCAGGATTTCTATAGCCACAGCAACTGGGTAGAGCTGGGGGAGCGGCAGCCACACC
CTCACCTCCTCTGGCCAAGGCGGGAACTCTGGAGCCTGGCCCAAGTGGGCGATCCTACCTGCTC
TGACTGCGAGGGGCTGAGCTGCCCTGGGAACATGATGAACTTGACAATGCTCACCTCTGGCTAC
TTCGGAACGAATCCCCCCAAACCTCCAGGGAAATGTAGCCATGGAGGTCGTTTTGACCAGAGCA
GCTCCCAGCCACCCCGGGGAGGCATCAACAAGGACAGCACATCCCCAAGCTTCTCCCCGCACCA
TAGGCTGCACCTCCAGGCTGCAGAAGTGGCACTGTTAGCTTCCATCGAGGCCCTCAGCCTCCTG
CGAAGCCGCCTGGGAACCAGGGGGTTCTCCAGGCTGCTGGACATCACCCCCGCTTCCAGCCTGA
GCTTCGTCCTGGACACCACAGGCAGTATGGGCGAGGAGATCAATGCAGCCAAGATCCAGGCTCG
ACGCATAGTGGAGCAGCGGCAAGGCAGCCCCATGGAGCCTGTTTCCTACATCCTGGTGCCCTTC
CACGACCCAGGGTTCGGCCCTGTCTTTACAACCAGTGACCCTGACAGCTTCTGGCAGAAACTCA
CCGAGATCCATGCCTTGGGAGGTGGAGATGAGCCGGAGATGTGCTTGTCTGCCCTGGAGCTAGC
CCTGCTGCATACACCTCCCCTCTCAGACATCTTCGTCTTCACTGACGCCTCCCCCAAGGACGCT
TTTCTTACCAACCGGGTGGAATCCCTGACTCGGGAGAGGCGCTGCAGGGTCACGTTCCTAGTAA
CCGAAGACCCATCGAGGGCTCAGGGTCGAGGACGGCGAGAGGCCTTGTCTCCTTCTCGCTTTGA
GCCATACGAAGCAATAGCCCTGGCATCGGGGGGAGAGGTGATCTTTACCAAAGACCAGCACATC
CGGGATGTGGCTGCCGTTGTTGGGGAGAGCATGGCTGGTCTGGTGACTCTTCCCCTGGAGCCTC
CCATCTTCACCCCCGGGGAGCCCTGTGTGTTCGCTGTGGACAGTCTGCTCTCGAAAGTCACAGT
CCGAATGCACGGGGACATCAGTGGCTTCTGGATCAAGAGCCCTGCAGGGTTGTCCCAGGGCCCA
GAGGAGGGCATAGGTCCTCTGGGCCACACTCGTCGCTTTGGGCAGTTCTGGACAGTGACCATGA
CTGACCCCCCTCAGACAGGGTCTTGGGAGATCCAGGTAGCAGCTGAGGGAACCCCCCGGGTGAG
AGTACAAGCCCAGACCTCTCTGGACTTCCTGTTTCACTTCGGGATCTCTGCAGAGGATGGACCC
CACCCTGGCCTCTACCCCCTGACTCAGCCAGTTGCAGGTCTTCAGACCCAGCTGCTGGTAGAAG
TGACAGGGCTCGTCTCTAGACAGAAACTTGGAGATGGCCAGCCACAGTTTTCCCATGCTGTCCT
TCGAAGGGTCTCAGAGGGCACTCATCTGGGCCGGGTGTCCTTGGAGCCCGTGGGACCCCCGGAG
CGAGGCCTCCTTGCTGCCTCGCTACCGCCCACACTGCTGTCTGTCTCTGTACCCTTCTCCCTGG
AGCTGGTTGGCCAGGATGTAGGGGGACAGTGTCTGCGGAGGTCTGCTCCCCAGCCTTGCAGTGT
GGCTCCCGTGCTTCTGGAGCTCAGTGGCCCGCCAGATTTCTTGACTCCGGGCAGCAAGGCCCCT
CTCAGCCTCCGAGTCGCCAGCTTCTCTGGCCCCCAGGATGTTGATCTTAGGTCATCCGTGAACC
CTAGCTTCTCCCTCACCTCCAACCTCTCCAGGGCTCGCCTGGGACTGAACGAGTCTGCCTGGGG
ATGCCTGTGGCTAGAGGTCCCAGATTCAGCAGCCCCTGACACTGTGGTGACTGTGACTGTGACT
GTGACTGCAGTGGGTCAGGGAGCCAGCCAGGTGCCCCCAACCCATGCCTTCCTCCAGCTCCTGG
TGCTGGCCCAGTCCTCAAAGGACCAGCTGGAGGACCCCACCCACTCAGCTGCCCCTGTGCTGCC
CCCAACCACCCCCGCCCTGCTTCCTTCCACTTTGGTGACTCGGGGCAGAGCTGGGAGAGGGACA
ACAGGCAAAACCTGGTGGGGGACAGTTGGAGGTGTGCTGTTCCTGCTAGGCTGCACTTCCTGGT
AACACAGGGACAGGGCATCGGGCCCCATTCTCAGTCTGCCCTATGGGTGGGATGCTCACATGGC
TTCAGAGCCCTGCCCTGCCTACCTGGTGTGGGGATTTTTTTTTTAAAGATCTATTTATTTATTA
TATCCATAATGTTCTGCACATATATATAAATATCTGCATGTCAAAAGAGGGTACCAGATCTCAT
TACAGATGGTTGTGAGCCACCATGTGGTTGCTGGGAATTGAACTCAGGTCCTCTGGAAGAACAA
TCAGTGGTCTCAACCTCTGAGCCATCTCTCCAGCCCAGGGATCTTTCTTCTATCACATTTGTCC
CTTATCTTTCTTTAGACCAGACTGGCCTCACAGACCTGCCTCTGCGTGTCTTCCTACCGCAGGG
ATCAAAGGCATGCACTGCTGCTGCCTGGCTCCTTTGTCTTTCTAAGACGAGTAGACTGGTGTGC
ACAGGTGGTACAACTTGTAGTCCCTGTAACAGGAAGGACTGCTGCTGTGAGTTCAAGGCCAGCC
TGAGCTATGAGACCCTAGCTCAAAAACATCAATCAAACACACACACACACACACACACACACAC
ACACACACACAGGATTGGGATCTAGGATGATGGGTTTCCCTTGGGGTGCTTTTCCTAACCCCAA
CGGGAACCAAACCAAAGGCTTTCCTTTTCTCTCTCTCTCTCTTTTTTTTTTTTTTTTTTTTTTT
TTTTTAAGAGAGCTGCTGTTTATTCCAGAAGCAGAGCAGGGCAGGGGCACCAGAAAGTACAATT
TTCCTTTAAATTCCAGGGCAGCTTTTTTAGCTTAGTTTTGCTTCAAGCTGAAGGAGAGTCTCCT
TGATCACGCCTCCTCCCCAAATACACTGAAGAAAGACAGGGCTTTGTAGTGGCATGGGGGAGAG
GGAGGGCAAGGGATGTCAAGGAAGTGCGGTGGACACTTTTAGGAGTTGCAGGAGCACTCTACTG
AGTTGTCTGAATTTCTCAGCCTGGAGCCACTGGCTGCTGAATGAAGATTAAATAGATGAGGGGG
GCAGGGGCAGGGGCAGGGGACTCTGACTCCAACCCCACTCCTTACACCAGTGCAGGGAGGGGAG
GGTTTACACAAGGGTAGGCCCCTTTGCTCCTGGTGGGGGAGCCTGGCTGATCACCTCTCCTGTT
CGATGGCTGACTCCTTTCTGCTGCTTTGACAACTCCTGAAAGAGAGAGAACCAGCCTGGCACCC
GCCACTCACCCTGTGGGTTTGTCAGCCAGGGCTCAACACCCCTCAGCTTACCCATCGCTGCCAC
AAGTTCTCTGCCTTGGCATTCCCTCCTGGCCCTGGGCTGCACAGGAATCAGTTTTTCCAGTGGA
TACGGGCAAGGCCGAATCAACCTGACTCCACAAGCCCCCTCCCCGAAGTCTAGAAATTAAGAAC
AATAAACTCACCTTCTGAATCAGACTGCGCAAACAAGCATTCACCTTTTGAATCCTGGT

hide sequence

RefSeq Acc Id:

XM_039098674 ⟹ XP_038954602

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,799,681 - 3,810,289 (-)	NCBI
mRatBN7.2	20	3,795,017 - 3,805,646 (-)	NCBI

RefSeq Acc Id:

XM_039098675 ⟹ XP_038954603

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,799,681 - 3,810,289 (-)	NCBI
mRatBN7.2	20	3,795,017 - 3,805,646 (-)	NCBI

RefSeq Acc Id:

XM_063279117 ⟹ XP_063135187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,799,681 - 3,809,982 (-)	NCBI

RefSeq Acc Id:

XM_063279118 ⟹ XP_063135188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,802,090 - 3,810,289 (-)	NCBI

RefSeq Acc Id:

XR_010060676

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	3,801,412 - 3,810,289 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_997664	(Get FASTA)	NCBI Sequence Viewer
	XP_038954602	(Get FASTA)	NCBI Sequence Viewer
	XP_038954603	(Get FASTA)	NCBI Sequence Viewer
	XP_063135187	(Get FASTA)	NCBI Sequence Viewer
	XP_063135188	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAE83982	(Get FASTA)	NCBI Sequence Viewer
	EDL83487	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001153
	ENSRNOP00000001153.2
GenBank Protein	Q6MG64	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_997664 ⟸ NM_212499
- Peptide Label:	precursor
- UniProtKB:	Q6MG64 (UniProtKB/Swiss-Prot), A6KTQ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPVEVPLSQLGPPVLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLELFLEQP PPGRPHLHLEDYRGRTLLADDIFAAYFGSGFSSRRFRAALGEVSRANAAQDFLPASKSNPDLHF DAERLVQGRTRLEGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLL WPRRELWSLAQVGDPTCSDCEGLSCPGNMMNLTMLTSGYFGTNPPKPPGKCSHGGRFDQSSSQP PRGGINKDSTSPSFSPHHRLHLQAAEVALLASIEALSLLRSRLGTRGFSRLLDITPASSLSFVL DTTGSMGEEINAAKIQARRIVEQRQGSPMEPVSYILVPFHDPGFGPVFTTSDPDSFWQKLTEIH ALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDAFLTNRVESLTRERRCRVTFLVTEDP SRAQGRGRREALSPSRFEPYEAIALASGGEVIFTKDQHIRDVAAVVGESMAGLVTLPLEPPIFT PGEPCVFAVDSLLSKVTVRMHGDISGFWIKSPAGLSQGPEEGIGPLGHTRRFGQFWTVTMTDPP QTGSWEIQVAAEGTPRVRVQAQTSLDFLFHFGISAEDGPHPGLYPLTQPVAGLQTQLLVEVTGL VSRQKLGDGQPQFSHAVLRRVSEGTHLGRVSLEPVGPPERGLLAASLPPTLLSVSVPFSLELVG QDVGGQCLRRSAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLRVASFSGPQDVDLRSSVNPSFS LTSNLSRARLGLNESAWGCLWLEVPDSAAPDTVVTVTVTVTAVGQGASQVPPTHAFLQLLVLAQ SSKDQLEDPTHSAAPVLPPTTPALLPSTLVTRGRAGRGTTGKTWWGTVGGVLFLLGCTSW hide sequence

Ensembl Acc Id:

ENSRNOP00000001153 ⟸ ENSRNOT00000001153

RefSeq Acc Id:	XP_038954603 ⟸ XM_039098675
- Peptide Label:	isoform X1
- UniProtKB:	A6KTQ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954602 ⟸ XM_039098674
- Peptide Label:	isoform X1
- UniProtKB:	A6KTQ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135187 ⟸ XM_063279117
- Peptide Label:	isoform X1
- UniProtKB:	A6KTQ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135188 ⟸ XM_063279118
- Peptide Label:	isoform X2

Protein Domains

Hemicentin-1-like von Willebrand factor A Hemicentin/VWA7 galactose-binding VWA7 beta-sandwich VWA7 Ig-like VWA7 N-terminal VWFA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MG64-F1-model_v2	AlphaFold	Q6MG64	1-892	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303137	AgrOrtholog
BioCyc Gene	G2FUF-4630	BioCyc
Ensembl Genes	ENSRNOG00000000860	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000001153	ENTREZGENE
	ENSRNOT00000001153.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.410	UniProtKB/Swiss-Prot
InterPro	GBD_Hemicentin/VWA7	UniProtKB/Swiss-Prot
	HMCN1-like_VWA	UniProtKB/Swiss-Prot
	VWA7	UniProtKB/Swiss-Prot
	VWA7_N	UniProtKB/Swiss-Prot
	vWFA_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:309611	UniProtKB/Swiss-Prot
NCBI Gene	309611	ENTREZGENE
PANTHER	NG37	UniProtKB/Swiss-Prot
	VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7	UniProtKB/Swiss-Prot
Pfam	GBD_Hemicentin	UniProtKB/Swiss-Prot
	Ig_VWA7	UniProtKB/Swiss-Prot
	VWA7_4	UniProtKB/Swiss-Prot
	VWA7_N	UniProtKB/Swiss-Prot
	VWA_4	UniProtKB/Swiss-Prot
PhenoGen	Vwa7	PhenoGen
RatGTEx	ENSRNOG00000000860	RatGTEx
Superfamily-SCOP	SSF53300	UniProtKB/Swiss-Prot
UniProt	A6KTQ7	ENTREZGENE, UniProtKB/TrEMBL
	Q6MG64	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-07-16	Vwa7	von Willebrand factor A domain containing 7	G7c	G7c protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	G7c	G7c protein			Symbol and Name status set to approved	1299863	APPROVED
2005-02-14	G7c	G7c protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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