Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Prrc2a | Rat | (+)-catechin | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Catechin results in increased expression of PRRC2A mRNA | CTD | PMID:15465739 | Prrc2a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Prrc2a (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PRRC2A mRNA] | CTD | PMID:22206623 | Prrc2a | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PRRC2A mRNA | CTD | PMID:22206623 | Prrc2a | Rat | 17beta-estradiol | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Estradiol results in increased expression of PRRC2A mRNA | CTD | PMID:39298647 | Prrc2a | Rat | 17beta-estradiol 3-benzoate | increases methylation | EXP | | 6480464 | estradiol 3-benzoate results in increased methylation of PRRC2A promoter | CTD | PMID:27415467 | Prrc2a | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of PRRC2A mRNA | CTD | PMID:31388691 | Prrc2a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PRRC2A mRNA | CTD | PMID:18796159 | Prrc2a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRRC2A mRNA | CTD | PMID:33387578 | Prrc2a | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of PRRC2A mRNA | CTD | PMID:21346803 | Prrc2a | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization more ... | CTD | PMID:38598786 | Prrc2a | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of PRRC2A mRNA | CTD | PMID:21346803 | Prrc2a | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | bisphenol S affects the expression of PRRC2A mRNA | CTD | PMID:39298647 | Prrc2a | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Prrc2a (Mus musculus) | 6480464 | bisphenol S affects the methylation of PRRC2A gene | CTD | PMID:31683443 | Prrc2a | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Prrc2a | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of PRRC2A gene | CTD | PMID:31601247 | Prrc2a | Rat | aflatoxin B1 | increases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PRRC2A exon | CTD | PMID:30157460 | Prrc2a | Rat | arsane | affects methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRRC2A gene | CTD | PMID:25304211 | Prrc2a | Rat | arsenic atom | affects methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRRC2A gene | CTD | PMID:25304211 | Prrc2a | Rat | atrazine | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Atrazine results in increased expression of PRRC2A mRNA | CTD | PMID:22378314 | Prrc2a | Rat | benzo[a]pyrene | affects methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PRRC2A exon | CTD | PMID:30157460 | Prrc2a | Rat | benzo[e]pyrene | increases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of PRRC2A exon | CTD | PMID:30157460 | Prrc2a | Rat | beta-lapachone | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of PRRC2A mRNA | CTD | PMID:38218311 | Prrc2a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PRRC2A mRNA | CTD | PMID:25181051 | Prrc2a | Rat | bisphenol A | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PRRC2A mRNA | CTD | PMID:38074096 | Prrc2a | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Prrc2a | Rat | bisphenol A | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PRRC2A protein | CTD | PMID:37567409 | Prrc2a | Rat | bisphenol A | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRRC2A gene | CTD | PMID:31601247 | Prrc2a | Rat | bisphenol A | increases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of PRRC2A gene | CTD | PMID:31601247 | Prrc2a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PRRC2A mRNA | CTD | PMID:30816183|PMID:32145629 | Prrc2a | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Prrc2a | Rat | buta-1,3-diene | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | 1,3-butadiene results in decreased expression of PRRC2A mRNA | CTD | PMID:29038090 | Prrc2a | Rat | butanal | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of PRRC2A mRNA | CTD | PMID:26079696 | Prrc2a | Rat | Butylbenzyl phthalate | increases methylation | ISO | Prrc2a (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of PRRC2A exon | CTD | PMID:28392331 | Prrc2a | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of PRRC2A mRNA | CTD | PMID:19167457 | Prrc2a | Rat | cadmium dichloride | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PRRC2A mRNA | CTD | PMID:38382870 | Prrc2a | Rat | caffeine | affects phosphorylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PRRC2A protein | CTD | PMID:35688186 | Prrc2a | Rat | carbon nanotube | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of PRRC2A mRNA | CTD | PMID:25554681 | Prrc2a | Rat | CGP 52608 | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PRRC2A gene] | CTD | PMID:28238834 | Prrc2a | Rat | cisplatin | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PRRC2A mRNA | CTD | PMID:27594783 | Prrc2a | Rat | clozapine | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Clozapine results in decreased expression of PRRC2A mRNA | CTD | PMID:18797397 | Prrc2a | Rat | coumarin | affects phosphorylation | ISO | PRRC2A (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of PRRC2A protein | CTD | PMID:35688186 | Prrc2a | Rat | coumestrol | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Coumestrol results in increased expression of PRRC2A mRNA | CTD | PMID:19167446 | Prrc2a | Rat | coumestrol | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRRC2A mRNA | CTD | PMID:19167446 | Prrc2a | Rat | deoxynivalenol | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of PRRC2A protein | CTD | PMID:39638853 | Prrc2a | Rat | dicrotophos | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | dicrotophos results in increased expression of PRRC2A mRNA | CTD | PMID:28302478 | Prrc2a | Rat | Enterolactone | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRRC2A mRNA | CTD | PMID:19167446 | Prrc2a | Rat | enzyme inhibitor | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Prrc2a | Rat | ethanol | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Ethanol results in decreased expression of PRRC2A mRNA | CTD | PMID:29018328 | Prrc2a | Rat | ethanol | affects splicing | ISO | Prrc2a (Mus musculus) | 6480464 | Ethanol affects the splicing of PRRC2A mRNA | CTD | PMID:30319688 | Prrc2a | Rat | ethanol | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Ethanol results in increased expression of PRRC2A mRNA | CTD | PMID:30319688 | Prrc2a | Rat | flavonoids | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Flavonoids results in increased expression of PRRC2A mRNA | CTD | PMID:15465739 | Prrc2a | Rat | folic acid | multiple interactions | ISO | Prrc2a (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PRRC2A mRNA] | CTD | PMID:22206623 | Prrc2a | Rat | FR900359 | affects phosphorylation | ISO | PRRC2A (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PRRC2A protein | CTD | PMID:37730182 | Prrc2a | Rat | fulvestrant | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRRC2A gene | CTD | PMID:31601247 | Prrc2a | Rat | fulvestrant | increases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of PRRC2A gene | CTD | PMID:31601247 | Prrc2a | Rat | furfural | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization more ... | CTD | PMID:38598786 | Prrc2a | Rat | gold atom | multiple interactions | ISO | Prrc2a (Mus musculus) | 6480464 | [Gold co-treated with Polyethylene Glycols] results in increased expression of PRRC2A mRNA | CTD | PMID:19695318 | Prrc2a | Rat | gold(0) | multiple interactions | ISO | Prrc2a (Mus musculus) | 6480464 | [Gold co-treated with Polyethylene Glycols] results in increased expression of PRRC2A mRNA | CTD | PMID:19695318 | Prrc2a | Rat | haloperidol | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Haloperidol results in decreased expression of PRRC2A mRNA | CTD | PMID:18797397 | Prrc2a | Rat | ivermectin | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PRRC2A protein | CTD | PMID:32959892 | Prrc2a | Rat | methapyrilene | increases methylation | ISO | PRRC2A (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of PRRC2A exon | CTD | PMID:30157460 | Prrc2a | Rat | methidathion | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | methidathion affects the expression of PRRC2A mRNA | CTD | PMID:34813904 | Prrc2a | Rat | nitrofen | decreases expression | EXP | | 6480464 | nitrofen results in decreased expression of PRRC2A mRNA | CTD | PMID:33484710 | Prrc2a | Rat | olanzapine | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | olanzapine results in decreased expression of PRRC2A mRNA | CTD | PMID:18797397 | Prrc2a | Rat | ozone | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of PRRC2A mRNA | CTD | PMID:35430440 | Prrc2a | Rat | paracetamol | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | Acetaminophen affects the expression of PRRC2A mRNA | CTD | PMID:17562736 | Prrc2a | Rat | paracetamol | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PRRC2A mRNA | CTD | PMID:22230336 | Prrc2a | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Prrc2a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of PRRC2A mRNA | CTD | PMID:36331819 | Prrc2a | Rat | phenobarbital | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | Phenobarbital affects the expression of PRRC2A mRNA | CTD | PMID:19136022 | Prrc2a | Rat | pirinixic acid | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | pirinixic acid affects the expression of PRRC2A mRNA | CTD | PMID:19136022 | Prrc2a | Rat | progesterone | decreases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Progesterone results in decreased expression of PRRC2A mRNA | CTD | PMID:18070364 | Prrc2a | Rat | resveratrol | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | resveratrol results in increased expression of PRRC2A mRNA | CTD | PMID:12002526 | Prrc2a | Rat | resveratrol | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PRRC2A mRNA | CTD | PMID:23557933 | Prrc2a | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of PRRC2A protein | CTD | PMID:35544339 | Prrc2a | Rat | sodium arsenite | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PRRC2A mRNA | CTD | PMID:39719251 | Prrc2a | Rat | sodium chloride | multiple interactions | ISO | PRRC2A (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in increased expression of and affects the more ... | CTD | PMID:38598786 | Prrc2a | Rat | sodium dodecyl sulfate | affects response to substance | ISO | PRRC2A (Homo sapiens) | 6480464 | PRRC2A SNP affects the susceptibility to Sodium Dodecyl Sulfate | CTD | PMID:27258892 | Prrc2a | Rat | thiram | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Thiram results in increased expression of PRRC2A mRNA | CTD | PMID:38568856 | Prrc2a | Rat | titanium dioxide | increases expression | ISO | Prrc2a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PRRC2A mRNA | CTD | PMID:29264374 | Prrc2a | Rat | titanium dioxide | decreases methylation | ISO | Prrc2a (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PRRC2A gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Prrc2a | Rat | triphenyl phosphate | affects expression | ISO | PRRC2A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PRRC2A mRNA | CTD | PMID:37042841 | Prrc2a | Rat | troglitazone | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | troglitazone results in decreased expression of PRRC2A mRNA | CTD | PMID:28973697 | Prrc2a | Rat | tungsten | decreases expression | ISO | Prrc2a (Mus musculus) | 6480464 | Tungsten results in decreased expression of PRRC2A mRNA | CTD | PMID:30912803 | Prrc2a | Rat | urethane | increases expression | ISO | PRRC2A (Homo sapiens) | 6480464 | Urethane results in increased expression of PRRC2A mRNA | CTD | PMID:28818685 | Prrc2a | Rat | valproic acid | affects expression | ISO | Prrc2a (Mus musculus) | 6480464 | Valproic Acid affects the expression of PRRC2A mRNA | CTD | PMID:17292431 | Prrc2a | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of PRRC2A mRNA | CTD | PMID:29427782 | Prrc2a | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of PRRC2A mRNA | CTD | PMID:20566332 | Prrc2a | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PRRC2A mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















