Pfdn6 (prefoldin subunit 6) - Rat Genome Database

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Gene: Pfdn6 (prefoldin subunit 6) Rattus norvegicus
Analyze
Symbol: Pfdn6
Name: prefoldin subunit 6
RGD ID: 1303006
Description: Predicted to enable amyloid-beta binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone-mediated protein complex assembly; negative regulation of amyloid fibril formation; and protein folding. Predicted to be part of RPAP3/R2TP/prefoldin-like complex and prefoldin complex. Predicted to be active in cytoplasm. Orthologous to human PFDN6 (prefoldin subunit 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ke2; MHC class II region expressed gene KE2; prefoldin 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,947,844 - 4,949,318 (+)NCBIGRCr8
mRatBN7.2204,945,959 - 4,947,433 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,945,959 - 4,947,433 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,669,442 - 5,670,913 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,031,187 - 5,032,658 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,511,980 - 5,513,454 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,455,974 - 5,457,448 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,455,974 - 5,457,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,514,586 - 7,516,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,097,725 - 5,099,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1205,097,988 - 5,099,417 (+)NCBI
Celera206,530,176 - 6,531,651 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pfdn6Ratautosomal dominant intellectual developmental disorder 5  ISOPFDN6 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and autosomal dominant 5ClinVarPMID:28492532
Pfdn6RatMHC class I deficiency  ISOPFDN6 (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class I deficiencyClinVarPMID:28492532
Pfdn6Ratproteasome-associated autoinflammatory syndrome 1  ISOPFDN6 (Homo sapiens)8554872ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1ClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pfdn6Rat1,2-dimethylhydrazine increases expressionISOPfdn6 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PFDN6 mRNACTDPMID:22206623
Pfdn6Rat1,2-dimethylhydrazine multiple interactionsISOPfdn6 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PFDN6 mRNACTDPMID:22206623
Pfdn6Rat17alpha-ethynylestradiol multiple interactionsISOPfdn6 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PFDN6 mRNACTDPMID:17942748
Pfdn6Rat17alpha-ethynylestradiol increases expressionISOPfdn6 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of PFDN6 mRNACTDPMID:17942748
Pfdn6Rat17beta-estradiol decreases expressionISOPfdn6 (Mus musculus)6480464Estradiol results in decreased expression of PFDN6 mRNACTDPMID:39298647
Pfdn6Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOPfdn6 (Mus musculus)64804642 more ...CTDPMID:30294300
Pfdn6Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PFDN6 mRNACTDPMID:21215274 more ...
Pfdn6Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPfdn6 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PFDN6 mRNACTDPMID:17942748
Pfdn6Rat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Pfdn6Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PFDN6 mRNACTDPMID:36041667
Pfdn6Rataflatoxin B1 decreases expressionISOPFDN6 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of PFDN6 mRNACTDPMID:21641981
Pfdn6Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PFDN6 mRNACTDPMID:16483693
Pfdn6Ratantirheumatic drug increases expressionISOPFDN6 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of PFDN6 mRNACTDPMID:24449571
Pfdn6Ratarsenite(3-) multiple interactionsISOPFDN6 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to PFDN6 mRNA]CTDPMID:32406909
Pfdn6Ratbenzalkonium chloride affects response to substanceISOPFDN6 (Homo sapiens)6480464PFDN6 SNP affects the susceptibility to Benzalkonium CompoundsCTDPMID:27258892
Pfdn6Ratbenzo[a]pyrene affects methylationISOPFDN6 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of PFDN6 promoterCTDPMID:27901495
Pfdn6Ratbis(2-ethylhexyl) phthalate increases expressionISOPfdn6 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of PFDN6 mRNACTDPMID:33754040
Pfdn6Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of PFDN6 mRNACTDPMID:25181051
Pfdn6Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PFDN6 mRNACTDPMID:36041667
Pfdn6Ratbisphenol A decreases methylationISOPFDN6 (Homo sapiens)6480464bisphenol A results in decreased methylation of PFDN6 geneCTDPMID:31601247

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Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pfdn6Ratbiological_process  ND 159840702/2010: no relevant rat dataRGD 
Pfdn6Ratchaperone-mediated protein complex assembly involved_inISOPFDN6 (Homo sapiens)1624291 PMID:9630229RGDPMID:9630229
Pfdn6Ratchaperone-mediated protein complex assembly involved_inIBAPANTHER:PTN000484524 and UniProtKB:O152121600115GO_REF:0000033GO_CentralGO_REF:0000033
Pfdn6Ratchaperone-mediated protein complex assembly involved_inIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6Ratnegative regulation of amyloid fibril formation involved_inISOPFDN6 (Homo sapiens)1624291 PMID:23614719RGDPMID:23614719
Pfdn6Ratnegative regulation of amyloid fibril formation involved_inIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6Ratprotein folding involved_inISOPFDN6 (Homo sapiens)1624291 PMID:30955883RGDPMID:30955883
Pfdn6Ratprotein folding involved_inIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6Ratprotein folding involved_inIEAInterPro:IPR0027771600115GO_REF:0000002InterProGO_REF:0000002
Pfdn6Ratprotein folding involved_inIBAPANTHER:PTN000484524 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 10 of 10 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pfdn6Ratcytoplasm is_active_inIBAPANTHER:PTN000484524 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pfdn6Ratprefoldin complex part_ofISOPFDN6 (Homo sapiens)1624291 PMID:23614719 more ...RGDPMID:23614719 more ...
Pfdn6Ratprefoldin complex part_ofIEAInterPro:IPR0027771600115GO_REF:0000002InterProGO_REF:0000002
Pfdn6Ratprefoldin complex part_ofIBAPANTHER:PTN000484524 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pfdn6Ratprefoldin complex part_ofIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6RatRPAP3/R2TP/prefoldin-like complex part_ofISOPFDN6 (Homo sapiens)1624291 PMID:31738558RGDPMID:31738558
Pfdn6RatRPAP3/R2TP/prefoldin-like complex part_ofIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pfdn6Ratamyloid-beta binding enablesISOPFDN6 (Homo sapiens)1624291 PMID:23614719RGDPMID:23614719
Pfdn6Ratamyloid-beta binding enablesIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6Ratprotein binding enablesISOPFDN6 (Homo sapiens)1624291UniProtKB:O15481 more ...RGDPMID:32296183 and PMID:32814053
Pfdn6Ratprotein-folding chaperone binding enablesISOPFDN6 (Homo sapiens)1624291 PMID:9630229RGDPMID:9630229
Pfdn6Ratprotein-folding chaperone binding enablesIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
Pfdn6Ratprotein-folding chaperone binding enablesIBAPANTHER:PTN000484524 and UniProtKB:O152121600115GO_REF:0000033GO_CentralGO_REF:0000033
Pfdn6Ratunfolded protein binding enablesISOPFDN6 (Homo sapiens)1624291 PMID:30955883RGDPMID:30955883
Pfdn6Ratunfolded protein binding enablesIEAInterPro:IPR0027771600115GO_REF:0000002InterProGO_REF:0000002
Pfdn6Ratunfolded protein binding enablesIEAUniProtKB:O15212 and ensembl:ENSP000003637341600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Expressional patterns of chaperones in ten human tumor cell lines. Myung JK, etal., Proteome Sci 2004 Dec 14;2(1):8.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:9630229   PMID:15060004   PMID:31505169  



Pfdn6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,947,844 - 4,949,318 (+)NCBIGRCr8
mRatBN7.2204,945,959 - 4,947,433 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,945,959 - 4,947,433 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,669,442 - 5,670,913 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,031,187 - 5,032,658 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,511,980 - 5,513,454 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,455,974 - 5,457,448 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,455,974 - 5,457,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,514,586 - 7,516,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,097,725 - 5,099,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1205,097,988 - 5,099,417 (+)NCBI
Celera206,530,176 - 6,531,651 (+)NCBICelera
Cytogenetic Map20p12NCBI
PFDN6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,289,197 - 33,290,934 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,289,302 - 33,298,401 (+)EnsemblGRCh38hg38GRCh38
GRCh37633,257,374 - 33,258,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,365,356 - 33,366,689 (+)NCBINCBI36Build 36hg18NCBI36
Build 34633,365,355 - 33,366,689NCBI
Celera634,811,736 - 34,813,069 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,999,008 - 33,000,345 (+)NCBIHuRef
CHM1_1633,259,314 - 33,260,651 (+)NCBICHM1_1
T2T-CHM13v2.0633,110,554 - 33,112,296 (+)NCBIT2T-CHM13v2.0
Pfdn6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,157,883 - 34,159,317 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,157,795 - 34,159,317 (-)EnsemblGRCm39 Ensembl
GRCm381733,938,909 - 33,940,343 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,938,821 - 33,940,343 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,075,854 - 34,077,288 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,549,377 - 33,550,759 (-)NCBIMGSCv36mm8
Celera1736,691,821 - 36,693,255 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Pfdn6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,848,571 - 1,849,824 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,848,571 - 1,849,824 (+)NCBIChiLan1.0ChiLan1.0
PFDN6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,767,049 - 47,768,838 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,638,721 - 43,640,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,861,793 - 32,863,234 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,975,889 - 33,977,304 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,975,992 - 33,983,245 (+)Ensemblpanpan1.1panPan2
PFDN6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,729,562 - 2,730,858 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,729,562 - 2,737,163 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,810,481 - 2,811,777 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0123,060,976 - 3,062,272 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,060,976 - 3,068,578 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,728,205 - 2,729,498 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,809,691 - 2,810,986 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,884,403 - 2,885,699 (+)NCBIUU_Cfam_GSD_1.0
Pfdn6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,383,438 - 38,384,733 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,575,534 - 25,576,818 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,575,534 - 25,576,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFDN6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl729,653,679 - 29,654,945 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1729,653,569 - 29,654,957 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,157,268 - 34,158,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PFDN6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,786,556 - 38,787,913 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1738,786,045 - 38,787,613 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604433,124,206 - 33,125,566 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfdn6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,531,016 - 23,532,388 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,531,016 - 23,532,350 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pfdn6
23 total Variants

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:44
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000000553
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7175096Tcs1T cell selection QTL 1T cell selection trait (VT:0004917)expression2047270785024580Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000000553   ⟹   ENSRNOP00000000553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,945,959 - 4,947,433 (+)Ensembl
Rnor_6.0 Ensembl205,455,974 - 5,457,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092555   ⟹   ENSRNOP00000075836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,456,235 - 5,457,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092676   ⟹   ENSRNOP00000075862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,455,974 - 5,457,444 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,456,013 - 5,456,724 (+)Ensembl
RefSeq Acc Id: NM_001164718   ⟹   NP_001158190
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,947,844 - 4,949,318 (+)NCBI
mRatBN7.2204,945,959 - 4,947,433 (+)NCBI
Rnor_6.0205,455,974 - 5,457,448 (+)NCBI
Rnor_5.0207,514,586 - 7,516,060 (+)NCBI
RGSC_v3.4205,097,725 - 5,099,199 (+)RGD
Celera206,530,176 - 6,531,651 (+)RGD
Sequence:
RefSeq Acc Id: NM_212506   ⟹   NP_997671
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,947,844 - 4,949,318 (+)NCBI
mRatBN7.2204,945,959 - 4,947,433 (+)NCBI
Rnor_6.0205,455,974 - 5,457,448 (+)NCBI
Rnor_5.0207,514,586 - 7,516,060 (+)NCBI
RGSC_v3.4205,097,725 - 5,099,199 (+)RGD
Celera206,530,176 - 6,531,651 (+)RGD
Sequence:
Protein RefSeqs NP_001158190 (Get FASTA)   NCBI Sequence Viewer  
  NP_997671 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAE83922 (Get FASTA)   NCBI Sequence Viewer  
  EDL96846 (Get FASTA)   NCBI Sequence Viewer  
  EDL96847 (Get FASTA)   NCBI Sequence Viewer  
  EDL96848 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000553
  ENSRNOP00000000553.2
RefSeq Acc Id: NP_997671   ⟸   NM_212506
- UniProtKB: Q6MGC4 (UniProtKB/TrEMBL),   F7EQJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001158190   ⟸   NM_001164718
- UniProtKB: Q6MGC4 (UniProtKB/TrEMBL),   F7EQJ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075862   ⟸   ENSRNOT00000092676
Ensembl Acc Id: ENSRNOP00000075836   ⟸   ENSRNOT00000092555
Ensembl Acc Id: ENSRNOP00000000553   ⟸   ENSRNOT00000000553

Name Modeler Protein Id AA Range Protein Structure
AF-Q6MGC4-F1-model_v2 AlphaFold Q6MGC4 1-127 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701413
Promoter ID:EPDNEW_R11936
Type:multiple initiation site
Name:Pfdn6_1
Description:prefoldin subunit 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,455,996 - 5,456,056EPDNEW


1 to 18 of 18 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-4517 BioCyc
Ensembl Genes ENSRNOG00000000473 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000553 ENTREZGENE
  ENSRNOT00000000553.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro PFD_beta-like UniProtKB/TrEMBL
  Prefoldin UniProtKB/TrEMBL
KEGG Report rno:309629 UniProtKB/TrEMBL
NCBI Gene 309629 ENTREZGENE
PANTHER PREFOLDIN SUBUNIT 6 UniProtKB/TrEMBL
  PREFOLDIN SUBUNIT 6 UniProtKB/TrEMBL
Pfam Prefoldin_2 UniProtKB/TrEMBL
PharmGKB PFDN6 RGD
PhenoGen Pfdn6 PhenoGen
RatGTEx ENSRNOG00000000473 RatGTEx
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt F7EQJ2 ENTREZGENE, UniProtKB/TrEMBL
  Q6MGC4 ENTREZGENE, UniProtKB/TrEMBL
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-10-22 Pfdn6  prefoldin subunit 6  Pfdn6  prefoldin 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-11 Pfdn6  prefoldin 6  Pfdn6  prefoldin subunit 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Pfdn6  prefoldin subunit 6  Ke2  MHC class II region expressed gene KE2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ke2  MHC class II region expressed gene KE2      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Ke2  MHC class II region expressed gene KE2      Symbol and Name status set to provisional 70820 PROVISIONAL