Ddah2 (DDAH family member 2, ADMA-independent) - Rat Genome Database

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Gene: Ddah2 (DDAH family member 2, ADMA-independent) Rattus norvegicus
Analyze
Symbol: Ddah2
Name: DDAH family member 2, ADMA-independent
RGD ID: 1302955
Description: Predicted to be located in mitochondrion. Orthologous to human DDAH2 (DDAH family member 2, ADMA-independent); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDAH-2; DDAHII; dimethylargininase-2; dimethylarginine dimethylaminohydrolase 2; inactive dimethylarginine dimethylaminohydrolase 2; inactive N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; MGC105993; n(G),N(G)-dimethylarginine dimethylaminohydrolase 2; putative hydrolase DDAH2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,766,115 - 3,769,161 (-)NCBIGRCr8
mRatBN7.2203,761,460 - 3,764,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,761,465 - 3,764,511 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,460,950 - 4,463,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,823,004 - 3,826,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,360,895 - 4,363,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,049,260 - 5,052,573 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,049,496 - 5,052,585 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,122,457 - 7,125,503 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,829,767 - 3,836,141 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,829,994 - 3,831,997 (-)NCBI
Celera204,261,560 - 4,264,603 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddah2Ratproteasome-associated autoinflammatory syndrome 1  ISODDAH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddah2Ratcoronary artery disease  ISODDAH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17267746
Ddah2Ratpre-eclampsia  ISODDAH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22285683

1 to 20 of 123 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddah2Rat1,2-dimethylhydrazine increases expressionISODdah2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of DDAH2 mRNACTDPMID:22206623
Ddah2Rat17alpha-ethynylestradiol decreases expressionISODdah2 (Mus musculus)6480464Ethinyl Estradiol results in decreased expression of DDAH2 mRNACTDPMID:17555576
Ddah2Rat17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of DDAH2 mRNACTDPMID:26865667
Ddah2Rat17alpha-ethynylestradiol affects expressionISODDAH2 (Homo sapiens)6480464Ethinyl Estradiol affects the expression of DDAH2 mRNACTDPMID:26865667
Ddah2Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of DDAH2 mRNACTDPMID:17557909
Ddah2Rat17beta-estradiol multiple interactionsISODDAH2 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of DDAH2 mRNA and [Progesterone co-treated with Estradiol] results in decreased expression of DDAH2 mRNACTDPMID:17404688 and PMID:30165855
Ddah2Rat17beta-estradiol decreases expressionISODDAH2 (Homo sapiens)6480464Estradiol results in decreased expression of DDAH2 mRNACTDPMID:23373633
Ddah2Rat17beta-estradiol affects expressionISODDAH2 (Homo sapiens)6480464Estradiol affects the expression of DDAH2 mRNACTDPMID:22574217
Ddah2Rat17beta-estradiol 3-benzoate increases methylationEXP 6480464estradiol 3-benzoate results in increased methylation of DDAH2 promoterCTDPMID:27415467
Ddah2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISODdah2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of DDAH2 mRNACTDPMID:19933214
Ddah2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODdah2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DDAH2 mRNACTDPMID:21570461
Ddah2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of DDAH2 mRNACTDPMID:22298810 and PMID:34747641
Ddah2Rat2-hydroxypropanoic acid decreases expressionISODDAH2 (Homo sapiens)6480464Lactic Acid results in decreased expression of DDAH2 mRNACTDPMID:30851411
Ddah2Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISODdah2 (Mus musculus)6480464tetrabromobisphenol A results in decreased expression of DDAH2 mRNACTDPMID:25172293
Ddah2Rat4,4'-sulfonyldiphenol increases expressionISODdah2 (Mus musculus)6480464bisphenol S results in increased expression of DDAH2 mRNACTDPMID:39298647
Ddah2Rat4,4'-sulfonyldiphenol affects methylationISODdah2 (Mus musculus)6480464bisphenol S affects the methylation of DDAH2 geneCTDPMID:31683443
Ddah2Rat4,4'-sulfonyldiphenol increases expressionISODDAH2 (Homo sapiens)6480464bisphenol S results in increased expression of DDAH2 proteinCTDPMID:34186270
Ddah2Rat4-hydroxyphenyl retinamide increases expressionISODdah2 (Mus musculus)6480464Fenretinide results in increased expression of DDAH2 mRNACTDPMID:28973697
Ddah2Rat5-fluorouracil affects response to substanceISODDAH2 (Homo sapiens)6480464DDAH2 protein affects the susceptibility to FluorouracilCTDPMID:16217747
Ddah2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of DDAH2 mRNACTDPMID:24780913

1 to 20 of 123 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddah2Ratcitrulline metabolic process NOT|involved_inISODDAH2 (Homo sapiens)1624291 PMID:21493890 and PMID:37296100RGDPMID:21493890 and PMID:37296100

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ddah2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ddah2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Ddah2Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Ddah2Ratmitochondrion located_inIEAUniProtKB:O95865 and ensembl:ENSP000003649451600115GO_REF:0000107EnsemblGO_REF:0000107
Ddah2Ratmitochondrion located_inIEAUniProtKB:V9HW53 and ensembl:ENSP000003649451600115GO_REF:0000107EnsemblGO_REF:0000107
Ddah2Ratmitochondrion located_inISODDAH2 (Homo sapiens)1624291 RGDGO_REF:0000052
Ddah2Ratmitochondrion located_inIEAUniProtKB-SubCell:SL-01731600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Leiper JM, etal., Biochem J 1999 Oct 1;343 Pt 1:209-14.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats. Sasaki A, etal., Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1480-7. Epub 2007 Feb 23.
PMID:12477932   PMID:15060004   PMID:15489334   PMID:17673667   PMID:18824664   PMID:19056867   PMID:19386725   PMID:19481782   PMID:19528264   PMID:21408057   PMID:21549701   PMID:22871113  
PMID:23376485   PMID:23533145   PMID:23619555   PMID:23702602   PMID:26911182   PMID:27957828   PMID:29119338  



Ddah2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,766,115 - 3,769,161 (-)NCBIGRCr8
mRatBN7.2203,761,460 - 3,764,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,761,465 - 3,764,511 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,460,950 - 4,463,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,823,004 - 3,826,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,360,895 - 4,363,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,049,260 - 5,052,573 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,049,496 - 5,052,585 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,122,457 - 7,125,503 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,829,767 - 3,836,141 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,829,994 - 3,831,997 (-)NCBI
Celera204,261,560 - 4,264,603 (+)NCBICelera
Cytogenetic Map20p12NCBI
DDAH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,727,040 - 31,730,263 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,727,038 - 31,730,617 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,694,817 - 31,698,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,802,796 - 31,806,018 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,802,796 - 31,806,018NCBI
Celera633,293,042 - 33,296,264 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,481,041 - 31,484,263 (-)NCBIHuRef
CHM1_1631,696,934 - 31,700,156 (-)NCBICHM1_1
T2T-CHM13v2.0631,580,073 - 31,583,296 (-)NCBIT2T-CHM13v2.0
Ddah2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,278,011 - 35,281,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,278,011 - 35,281,071 (+)EnsemblGRCm39 Ensembl
GRCm381735,059,035 - 35,062,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,059,035 - 35,062,095 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,195,980 - 35,199,044 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,667,157 - 34,670,151 (+)NCBIMGSCv36mm8
Celera1738,155,720 - 38,158,784 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Ddah2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437260,969 - 269,660 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437265,727 - 269,016 (-)NCBIChiLan1.0ChiLan1.0
DDAH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,204,269 - 46,207,547 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,165,770 - 42,169,008 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,388,401 - 31,391,637 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,277,102 - 32,280,336 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,277,102 - 32,280,338 (-)Ensemblpanpan1.1panPan2
DDAH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,206,180 - 1,209,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,206,309 - 1,208,389 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,342,719 - 1,346,021 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,351,545 - 1,354,847 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,351,552 - 1,354,808 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,210,814 - 1,214,096 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,278,042 - 1,281,342 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,345,682 - 1,348,984 (-)NCBIUU_Cfam_GSD_1.0
Ddah2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,753,903 - 35,757,640 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,804,455 - 1,807,183 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,803,711 - 1,807,441 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDAH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,838,993 - 23,842,516 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,838,993 - 23,842,514 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DDAH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,292,674 - 40,295,917 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,292,707 - 40,295,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,640,050 - 31,643,297 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddah2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,482,114 - 24,489,911 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,482,818 - 24,486,146 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ddah2
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:128
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000001118
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 24 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat

1 to 10 of 24 rows
RH128085  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,761,504 - 3,761,717 (-)MAPPERmRatBN7.2
Rnor_6.0205,052,316 - 5,052,528NCBIRnor6.0
Rnor_5.0207,125,246 - 7,125,458UniSTSRnor5.0
RGSC_v3.4203,829,812 - 3,830,024UniSTSRGSC3.4
Celera204,264,346 - 4,264,558UniSTS
RH 3.4 Map2049.3UniSTS
Cytogenetic Map20p12UniSTS
Clic1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,765,025 - 3,765,180 (-)MAPPERmRatBN7.2
Rnor_6.0205,048,853 - 5,049,007NCBIRnor6.0
Rnor_5.0207,121,783 - 7,121,937UniSTSRnor5.0
RGSC_v3.4203,499,094 - 3,499,248UniSTSRGSC3.4
Celera204,260,886 - 4,261,040UniSTS
Cytogenetic Map20p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000001118   ⟹   ENSRNOP00000001118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,049,505 - 5,052,572 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083353   ⟹   ENSRNOP00000068864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,050,327 - 5,052,572 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088251   ⟹   ENSRNOP00000069121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,761,465 - 3,764,511 (-)Ensembl
Rnor_6.0 Ensembl205,049,496 - 5,052,585 (+)Ensembl
RefSeq Acc Id: NM_001165936   ⟹   NP_001159408
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,766,115 - 3,768,413 (-)NCBI
mRatBN7.2203,761,460 - 3,763,758 (-)NCBI
Rnor_6.0205,050,275 - 5,052,573 (+)NCBI
Rnor_5.0207,122,457 - 7,125,503 (+)NCBI
RGSC_v3.4203,829,767 - 3,836,141 (-)RGD
Celera204,262,308 - 4,264,603 (+)NCBI
Sequence:
RefSeq Acc Id: NM_212532   ⟹   NP_997697
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,766,115 - 3,769,161 (-)NCBI
mRatBN7.2203,761,460 - 3,764,506 (-)NCBI
Rnor_6.0205,049,527 - 5,052,573 (+)NCBI
Rnor_5.0207,122,457 - 7,125,503 (+)NCBI
RGSC_v3.4203,829,767 - 3,836,141 (-)RGD
Celera204,261,560 - 4,264,603 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772715   ⟹   XP_008770937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,766,116 - 3,768,075 (-)NCBI
mRatBN7.2203,761,461 - 3,764,718 (-)NCBI
Rnor_6.0205,049,260 - 5,052,572 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063279000   ⟹   XP_063135070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,766,116 - 3,768,075 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001159408 (Get FASTA)   NCBI Sequence Viewer  
  NP_997697 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770937 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135070 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86443 (Get FASTA)   NCBI Sequence Viewer  
  AAH97930 (Get FASTA)   NCBI Sequence Viewer  
  CAE83986 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069121
  ENSRNOP00000069121.1
GenBank Protein Q6MG60 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_997697   ⟸   NM_212532
- UniProtKB: Q6MG60 (UniProtKB/Swiss-Prot),   A6KTR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159408   ⟸   NM_001165936
- UniProtKB: Q6MG60 (UniProtKB/Swiss-Prot),   A6KTR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770937   ⟸   XM_008772715
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000068864   ⟸   ENSRNOT00000083353
Ensembl Acc Id: ENSRNOP00000069121   ⟸   ENSRNOT00000088251

Name Modeler Protein Id AA Range Protein Structure
AF-Q6MG60-F1-model_v2 AlphaFold Q6MG60 1-285 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701386
Promoter ID:EPDNEW_R11910
Type:initiation region
Name:Ddah2_1
Description:dimethylarginine dimethylaminohydrolase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11911  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,049,509 - 5,049,569EPDNEW
RGD ID:13701387
Promoter ID:EPDNEW_R11911
Type:multiple initiation site
Name:Ddah2_2
Description:dimethylarginine dimethylaminohydrolase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11910  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,050,251 - 5,050,311EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-4636 BioCyc
Ensembl Genes ENSRNOG00000000842 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000088251 ENTREZGENE
  ENSRNOT00000088251.2 UniProtKB/Swiss-Prot
Gene3D-CATH L-arginine/glycine Amidinotransferase, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7303579 IMAGE-MGC_LOAD
  IMAGE:7388716 IMAGE-MGC_LOAD
InterPro DDAH UniProtKB/Swiss-Prot
KEGG Report rno:294239 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105993 IMAGE-MGC_LOAD
  MGC:116040 IMAGE-MGC_LOAD
NCBI Gene 294239 ENTREZGENE
PANTHER PTHR12737 UniProtKB/Swiss-Prot
  PTHR12737:SF16 UniProtKB/Swiss-Prot
PhenoGen Ddah2 PhenoGen
RatGTEx ENSRNOG00000000842 RatGTEx
Superfamily-SCOP Pentein UniProtKB/Swiss-Prot
UniProt A6KTR6 ENTREZGENE, UniProtKB/TrEMBL
  A6KTR7 ENTREZGENE, UniProtKB/TrEMBL
  DDAH2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-03 Ddah2  DDAH family member 2, ADMA-independent  Ddah2  dimethylarginine dimethylaminohydrolase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ddah2  dimethylarginine dimethylaminohydrolase 2      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Ddah2  dimethylarginine dimethylaminohydrolase 2      Symbol and Name status set to provisional 70820 PROVISIONAL