| 619921 | Rhoa | ras homolog family member A | ENCODES a protein that exhibits GDP binding; GTP binding; GTPase activity; INVOLVED IN GTP metabolic process; microtubule depolymerization; negative regulation of canonical NF-kappaB signal transduction; PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; E-cadherin signaling pathway; eicosanoid signaling pathway; ASSOCIATED WITH acute myocardial infarction; asthma; Brain Injuries; FOUND IN axon; cytosol; dendrite; INTERACTS WITH (R,R,R)-alpha-tocopherol; (S)-(-)-perillyl alcohol; 1-octadec-9-enoylglycero-3-phosphate | 8 | 117870548 | 117904303 | Rat | 694 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1597692 | Rhoa-ps1 | ras homolog family member A, pseudogene 1 | ENCODES a pseudogene that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred) | X | 23147741 | 23148772 | Rat | 5 | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 3590 | Rock2 | Rho-associated coiled-coil containing protein kinase 2 | ENCODES a protein that exhibits endopeptidase activator activity (ortholog); protease binding (ortholog); protein kinase activity (ortholog); INVOLVED IN positive regulation of cardiac muscle hypertrophy; positive regulation of connective tissue growth factor production; positive regulation of conne ctive tissue replacement; PARTICIPATES IN chemokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; Wnt signaling pathway; ASSOCIATED WITH Left Ventricular Hypertrophy; primary biliary cholangitis; Animal Disease Models (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 45407823 | 45502773 | Rat | 354 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1303132 | Plekhg5 | pleckstrin homology and RhoGEF domain containing G5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN endothelial cell chemotaxis (ortholog); endothelial cell migration (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH autosomal dominant distal hered itary motor neuronopathy 14 (ortholog); autosomal recessive distal hereditary motor neuronopathy 4 (ortholog); Charcot-Marie-Tooth disease recessive intermediate C (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); endocytic vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; azoxystrobin | 5 | 167860730 | 167904229 | Rat | 131 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2319924 | Lamtor1l1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cholesterol homeostasis (ortholog); endosomal transport (orthol og); FOUND IN late endosome membrane; membrane raft; lysosomal membrane (ortholog) | X | 38446140 | 38447189 | Rat | 45 | old_gene_name | gene, protein-coding, INFERRED [RefSeq] |
| 735210 | Arhgef25 | Rho guanine nucleotide exchange factor 25 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN myofibril (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 64891260 | 64898382 | Rat | 80 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 735078 | Lamtor1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | ENCODES a protein that exhibits GTPase binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to nutrient levels (ortholog); cholesterol homeostasis (ortholog ); PARTICIPATES IN mTOR signaling pathway; FOUND IN late endosome membrane; membrane raft; FNIP-folliculin RagC/D GAP (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 165684001 | 165689698 | Rat | 136 | old_gene_name , ensembl_full_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620424 | Rock1 | Rho-associated coiled-coil containing protein kinase 1 | ENCODES a protein that exhibits small GTPase binding; protein serine/threonine kinase activity (ortholog); Rho-dependent protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization; positive regulation of gene expression; response to transforming growth factor beta; PA RTICIPATES IN E-cadherin signaling pathway; eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH Left Ventricular Hypertrophy; acute promyelocytic leukemia (ortholog); basal cell carcinoma (ortholog); FOUND IN synapse; cytoplasmic stress granule (ortholog); cytoskeleton (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 18 | 1387360 | 1509218 | Rat | 367 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1591979 | Kctd10 | potassium channel tetramerization domain containing 10 | ENCODES a protein that exhibits identical protein binding (ortholog); Notch binding (ortholog); INVOLVED IN angiogenesis (ortholog); heart development (ortholog); negative regulation of Notch signaling pathway (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); MKS complex (ortholog) ; nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 12 | 47890777 | 47909391 | Rat | 95 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735189 | Kctd13 | potassium channel tetramerization domain containing 13 | ENCODES a protein that exhibits protein domain specific binding; identical protein binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of DNA replication; cell migration (ortholog); negative regulation of Rho protein signal transduction (o rtholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant nocturnal frontal lobe epilepsy 5 (ortholog); spondylocostal dysostosis 5 (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 1 | 190965073 | 190983381 | Rat | 89 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3877 | Tnfaip1 | TNF alpha induced protein 1 | ENCODES a protein that exhibits cyclin binding; identical protein binding (ortholog); small GTPase binding (ortholog); INVOLVED IN positive regulation of DNA replication; cell migration (ortholog); immune response (ortholog); ASSOCIATED WITH Diabetic Nephropathies (ortholog); FOUND IN Cul3-RING ubiq uitin ligase complex (ortholog); cytoplasm (ortholog); endosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 63915824 | 63930514 | Rat | 118 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735071 | Rhoal1 | ras homolog family member A like 1 | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); PARTICIPATES IN chemokine mediated signaling pathway; colorectal cancer pathway; endocytosis pathway; FOUND IN cleavage furrow (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride | 4 | 96581411 | 96582783 | Rat | 20 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |