Mdm2 Gene Search Result

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13 records found for search term Mdm2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1305332	Mdm2	MDM2 proto-oncogene	ENCODES a protein that exhibits p53 binding; peroxisome proliferator activated receptor binding; receptor serine/threonine kinase binding; INVOLVED IN cellular response to alkaloid; cellular response to antibiotic; cellular response to estrogen stimulus; PARTICIPATES IN altered p53 signaling pathway ... (more) ; p53 signaling pathway; cell cycle pathway, mitotic; ASSOCIATED WITH Acute Experimental Pancreatitis; Brain Injuries; breast cancer; FOUND IN glutamatergic synapse; postsynaptic density; cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine	7	55176558	55201757	Rat	835	symbol , old_gene_name , PhenoGen , name	gene, protein-coding, VALIDATED [RefSeq]
1565672	Mtbp	MDM2 binding protein	INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of mitotic nuclear division (ortholog); protein localization to kinetochore (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); prostate cancer (ortholog); FOUND IN chromatin (ortholog); kin ... (more) etochore (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide	7	88862939	88945491	Rat	79	old_gene_name , name	gene, protein-coding, VALIDATED [RefSeq]
1309306	Mdm4	MDM4 regulator of p53	ENCODES a protein that exhibits enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN atrial septum development (ortholog); atrioventricular valve morphogenesis (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN altered p53 signaling pathway; p53 signaling pa ... (more) thway; ASSOCIATED WITH Alzheimer's disease (ortholog); Bone Marrow Failure Syndrome 6 (ortholog); Breast Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine	13	46922236	47068241	Rat	176	old_gene_name	gene, protein-coding, PROVISIONAL [RefSeq]
1305685	Naa25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil	12	40758909	40811192	Rat	66	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
620002	Cdk5rap3	CDK5 regulatory subunit associated protein 3	ENCODES a protein that exhibits protein-containing complex binding; cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of cyclin-depende ... (more) nt protein serine/threonine kinase activity; apoptotic nuclear changes (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine	10	82390845	82402814	Rat	199	description	gene, protein-coding, VALIDATED [RefSeq]
1308993	Marchf7	membrane associated ring-CH-type finger 7	ENCODES a protein that exhibits enzyme binding (ortholog); MDM2/MDM4 family protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN negative regulation of cilium assembly (ortholog); negative regulation of DNA damage response, signal transduction b ... (more) y p53 class mediator (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); FOUND IN centrosome (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine	3	65090640	65128768	Rat	110	description	gene, protein-coding, PROVISIONAL [RefSeq]
3369	Ppara	peroxisome proliferator activated receptor alpha	ENCODES a protein that exhibits DNA-binding transcription factor binding; MDM2/MDM4 family protein binding; mitogen-activated protein kinase kinase kinase binding; INVOLVED IN behavioral response to nicotine; cellular response to fructose stimulus; fatty acid me ... (more) tabolic process; PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; hepatitis C pathway; ASSOCIATED WITH alcohol use disorder; alcoholic hepatitis; Brain Injuries; FOUND IN fibrillar center (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH (+)-catechin; (+)-schisandrin B; (3-phenoxyphenyl)methanol	7	118712261	118780723	Rat	1519	description	gene, protein-coding, PROVISIONAL [RefSeq]
1306996	Psme3	proteasome activator subunit 3	ENCODES a protein that exhibits endopeptidase activator activity (ortholog); identical protein binding (ortholog); MDM2/MDM4 family protein binding (ortholog); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway (ortholog); regulation of pro ... (more) teasomal protein catabolic process (ortholog); PARTICIPATES IN antigen processing and presentation pathway; hepatitis C pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene	10	86757933	86765719	Rat	117	description	gene, protein-coding, PROVISIONAL [RefSeq]
1305243	Rfwd3	ring finger and WD repeat domain 3	ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog); p53 binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN DNA damage response (ortholog); double-strand break repair via homologous recombination (ortholog); int ... (more) erstrand cross-link repair (ortholog); ASSOCIATED WITH Fanconi anemia (ortholog); Fanconi anemia complementation group W (ortholog); Testicular Germ Cell Tumor (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; cobalt dichloride; ochratoxin A	19	56145221	56177871	Rat	106	description	gene, protein-coding, VALIDATED [RefSeq]
41394010	Rpl37	ribosomal protein L37	ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog); structural constituent of ribosome (ortholog); ubiquitin ligase inhibitor activity (ortholog); INVOLVED IN cytoplasmic translation (ortholog); positive regulation of signal transduction ... (more) by p53 class mediator (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; FOUND IN cytoplasm (ortholog); cytosolic large ribosomal subunit (ortholog); cytosolic ribosome (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine	2	55942827	55944905	Rat	135	description	gene, protein-coding, VALIDATED [RefSeq]
62026	Rps15	ribosomal protein S15	ENCODES a protein that exhibits structural constituent of ribosome; MDM2/MDM4 family protein binding (ortholog); ubiquitin ligase inhibitor activity (ortholog); INVOLVED IN liver regeneration; ribosomal small subunit assembly; positive regulation of signal trans ... (more) duction by p53 class mediator (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH insulinoma; Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosolic small ribosomal subunit; nucleoplasm; synapse; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol	7	10066572	10068167	Rat	167	description	gene, protein-coding, VALIDATED [RefSeq]
621037	Rps20	ribosomal protein S20	ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog); structural constituent of ribosome (ortholog); ubiquitin ligase inhibitor activity (ortholog); INVOLVED IN positive regulation of signal transduction by p53 class mediator (ortholog); P ... (more) ARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Colorectal Cancer 10 (ortholog); Diamond-Blackfan anemia (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytosolic small ribosomal subunit; cytoplasmic side of rough endoplasmic reticulum membrane (ortholog); cytosol (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine	5	21616687	21618068	Rat	168	description	gene, protein-coding, VALIDATED [RefSeq]
3889	Tp53	tumor protein p53	ENCODES a protein that exhibits MDM2/MDM4 family protein binding; RNA polymerase II-specific DNA-binding transcription factor binding; sequence-specific DNA binding; INVOLVED IN apoptotic signaling pathway; cellular response to heat; cellular response to hypoxia ... (more) ; PARTICIPATES IN altered p53 signaling pathway; endometrial cancer pathway; non-small cell lung carcinoma pathway; ASSOCIATED WITH abnormal vacuole morphology; decreased body weight; decreased testis weight; ASSOCIATED WITH bronchiolo-alveolar adenocarcinoma; bronchopulmonary dysplasia; colorectal cancer; FOUND IN chromatin; nucleus; PML body; INTERACTS WITH (+)-catechin; (+)-dexrazoxane; (+)-schisandrin B	10	54798871	54810300	Rat	4013	description	gene, protein-coding, REVIEWED [RefSeq]