| 2586 | F2r | coagulation factor II (thrombin) receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN establishment of synaptic specificity at neuromuscular junction; G protein-coupled receptor signaling pathway; negative r egulation of glomerular filtration; PARTICIPATES IN G protein mediated signaling pathway; protease mediated signaling via protease-activated receptor 1; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH abnormal nociception after inflammation; ASSOCIATED WITH brain edema; brain ischemia; Hyperalgesia; FOUND IN neuromuscular junction; plasma membrane; postsynaptic membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 28604066 | 28620579 | Rat | 396 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 13799351 | F2rem1Mcwi | coagulation factor II (thrombin) receptor; CRISPR/Cas9 induced mutant 1, Mcwi | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos. | | | | Rat | | symbol , description | gene, allele |
| 620866 | F2rl1 | F2R like trypsin receptor 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN positive regulation of glomerular filtration; vasodilation; cell-cell junction maintenance (ortholog); PARTICIPATES IN pr otease mediated signaling via protease-activated receptor 2; sleeping sickness pathway; ASSOCIATED WITH lung disease; asthma (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN early endosome (ortholog); plasma membrane (ortholog); pseudopodium (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether | 2 | 28507003 | 28519954 | Rat | 368 | symbol , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620872 | F2rl3 | F2R like thrombin or trypsin receptor 3 | ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); cholestasis (ortholog); peliosis hepatis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; C60 fullerene | 16 | 17151516 | 17153509 | Rat | 77 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620871 | F2rl2 | coagulation factor II (thrombin) receptor-like 2 | ENCODES a protein that exhibits proteinase-activated receptor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN insulin signaling pathway; protease mediated signaling via protease-activated receptor 3; FOUND IN apical plasma membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 2 | 28706766 | 28711808 | Rat | 130 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |