| 1306796 | Enam | enamelin | ENCODES a protein that exhibits structural constituent of tooth enamel (ortholog); INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); odontogenesis of dentin-containing tooth (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog) ; amelogenesis imperfecta type 1B (ortholog); amelogenesis imperfecta type 1C (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; cadmium dichloride | 14 | 19840773 | 19865476 | Rat | 46 | symbol , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 126925993 | Cftrem1Ang | cystic fibrosis transmembrane conductance regulator; CRISPR/Cas9 induced mutant 1, Ang | ASSOCIATED WITH abnormal enamel development; abnormal olfactory epithelium physiology; decreased body weight; ASSOCIATED WITH cystic fibrosis; dental enamel hypoplasia | | | | Rat | 11 | description | gene, allele |
| 126925995 | Cftrem2Ang | cystic fibrosis transmembrane conductance regulator; CRISPR/Cas9 induced mutant 2, Ang | ASSOCIATED WITH abnormal enamel development; abnormal olfactory epithelium physiology; absent vas deferens; ASSOCIATED WITH cystic fibrosis; dental enamel hypoplasia | | | | Rat | 12 | description | gene, allele |
| 1303228 | Klk4 | kallikrein-related peptidase 4 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); extracellular matrix disassembly (ortholog); ASSOCIATED WITH amelog enesis imperfecta (ortholog); amelogenesis imperfecta type 2A1 (ortholog); breast cancer (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; Cuprizon; genistein | 1 | 103480731 | 103485963 | Rat | 61 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308730 | Mmp20 | matrix metallopeptidase 20 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN amelogenesis (ortholog); extracellular matrix disassembly (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH amelogenesis imperfecta hypomaturation type 2A2 (ortholog); amelogenesis imperfecta type 1 C (ortholog); autosomal dominant intellectual developmental disorder 56 (ortholog); FOUND IN extracellular matrix (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; acetamide | 8 | 13074279 | 13114894 | Rat | 46 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306718 | Adgrf2 | adhesion G protein-coupled receptor F2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); gene expression (ortholog); ASSOCIATED WITH autistic diso rder (ortholog); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; lead diacetate; trichloroethene | 9 | 25735607 | 25745962 | Rat | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 2107 | Amelx | amelogenin, X-linked | ENCODES a protein that exhibits identical protein binding; structural constituent of tooth enamel; calcium ion binding (ortholog); INVOLVED IN response to calcium ion; response to nutrient; response to xenobiotic stimulus; ASSOCIATED WITH autosomal dominant hypo calcemia; amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1E (ortholog); FOUND IN endocytic vesicle; basement membrane (ortholog); cell surface (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 6-propyl-2-thiouracil | X | 28648803 | 28660099 | Rat | 85 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1592356 | Amtn | amelotin | INVOLVED IN odontogenesis of dentin-containing tooth; amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta type 3A (ortholog); amelogenesis imperfecta type 3B (ortholog); FOUND IN basement membrane; cell-cell junctio n; extracellular matrix; INTERACTS WITH 17beta-estradiol; bisphenol A; cadmium dichloride | 14 | 19932664 | 19945223 | Rat | 49 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2332 | Cftr | CF transmembrane conductance regulator | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); ATP hydrolysis activity (ortholog); bicarbonate transmembrane transporter activity (ortholog); INVOLVED IN bicarbonate transport; cellular response to anoxia; cellular response to heat; PARTICIPATES IN bile acid transport pathway; AS SOCIATED WITH abnormal chloride level; abnormal circulating protein level; abnormal enamel development; ASSOCIATED WITH autosomal recessive polycystic kidney disease; cholestasis; congenital bilateral absence of vas deferens; FOUND IN apical plasma membrane; basolateral plasma membrane; dendrite; INTERACTS WITH 17beta-estradiol; 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine | 4 | 47422084 | 47694646 | Rat | 773 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305571 | Cnnm4 | cyclin and CBS domain divalent metal cation transport mediator 4 | ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (ortholog); sodium ion transmembrane transporter activity (ortholog); INVOLVED IN enamel mineralization (ortholog); intracellular monoatomic cation homeostasis (ortholog); magnesium ion homeostasis (ortholog); ASSOCIATED WITH Amaurosis Hypertrichosis (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN dendrite; neuronal cell body; basolateral plasma membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; bisphenol A | 9 | 46207602 | 46246817 | Rat | 108 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2441 | Ctbp1 | C-terminal binding protein 1 | ENCODES a protein that exhibits NAD binding; PDZ domain binding; protein homodimerization activity; INVOLVED IN presynapse to nucleus signaling pathway; negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES I N Notch signaling pathway; chronic myeloid leukemia pathway; Notch signaling pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); HYPOTONIA, ATAXIA, DEVELOPMENTAL DELAY, AND TOOTH ENAMEL DEFECT SYNDROME (ortholog); FOUND IN cytoplasm; extrinsic component of presynaptic endocytic zone membrane; glutamatergic synapse; INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil | 14 | 81679956 | 81707331 | Rat | 199 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2508 | Dmp1 | dentin matrix acidic phosphoprotein 1 | ENCODES a protein that exhibits Hsp70 protein binding; calcium ion binding (ortholog); extracellular matrix binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); regulation of enam >el mineralization (ortholog); ASSOCIATED WITH autosomal recessive hypophosphatemic rickets (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); extracellular matrix (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A | 14 | 5833111 | 5867154 | Rat | 83 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306364 | Fam20a | FAM20A, golgi associated secretory pathway pseudokinase | ENCODES a protein that exhibits protein serine/threonine kinase activator activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN biomineral tissue development (ortholog); calcium ion homeostasis (ortholog); enamel mineralization (o rtholog); ASSOCIATED WITH amelogenesis imperfecta type 1G (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 10 | 95136799 | 95197176 | Rat | 133 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2628 | Fosl2 | FOS like 2, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN circadian rhythm; conditioned taste aversion; female pregnancy; ASSOCIATED WITH renal carcinoma; Reperfusion Injury; APLASIA CUTIS-ENAM n>EL DYSPLASIA SYNDROME (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription factor AP-1 complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 6 | 30017952 | 30039269 | Rat | 348 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620283 | Foxo1 | forkhead box O1 | ENCODES a protein that exhibits DNA-binding transcription factor activity; sequence-specific DNA binding; transcription coactivator binding; INVOLVED IN cellular response to dexamethasone stimulus; cellular response to hydrogen peroxide; enamel mineralization; P ARTICIPATES IN interleukin-6 signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; Insulin Resistance; metabolic dysfunction-associated steatotic liver disease; FOUND IN cytoplasm; nucleus; cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 138462974 | 138541420 | Rat | 669 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 6489816 | Odaph | odontogenesis associated phosphoprotein | INVOLVED IN positive regulation of biomineral tissue development (ortholog); positive regulation of enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta hypomaturation type 2A4 (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol (ortholog); 2-palmitoylglycerol (ortholog); acrylamide (ortholog) | 14 | 16356104 | 16364420 | Rat | 24 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563550 | Wdr72 | WD repeat domain 72 | INVOLVED IN ameloblast differentiation (ortholog); amelogenesis (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta hypomaturation type 2A3 (ortholog); amelogenesis imperfecta type 1C (ortholo g); FOUND IN cytoplasm (ortholog); endosome (ortholog); extracellular region (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 8 | 83718897 | 83902128 | Rat | 109 | description | gene, protein-coding, PROVISIONAL [RefSeq] |