| 620641 | Dap | death-associated protein | INVOLVED IN apoptotic process (ortholog); apoptotic signaling pathway (ortholog); negative regulation of autophagy (ortholog); ASSOCIATED WITH ulcerative colitis (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate | 2 | 83910113 | 83962673 | Rat | 119 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 727851 | Acbd3 | acyl-CoA binding domain containing 3 | ENCODES a protein that exhibits protein kinase A regulatory subunit binding (ortholog); INVOLVED IN lipid metabolic process (inferred); steroid biosynthetic process (inferred); FOUND IN Golgi membrane; Golgi apparatus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachloro dibenzodioxine; 2,4-dinitrotoluene | 13 | 94987643 | 95016356 | Rat | 106 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2854 | Iapp | islet amyloid polypeptide | ENCODES a protein that exhibits hormone activity; lipid binding; receptor ligand activity; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; amylin receptor signaling pathway; eating behavior; PARTICIPATES IN maturity-onset diabetes of the young pathway; ASSOCIAT ED WITH Experimental Diabetes Mellitus (ortholog); gastric ulcer (ortholog); type 1 diabetes mellitus (ortholog); FOUND IN extracellular space (ortholog); inclusion body (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; 3,3',5,5'-tetrabromobisphenol A; acrylamide | 4 | 176968097 | 176975363 | Rat | 147 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620223 | Dlgap1 | DLG associated protein 1 | ENCODES a protein that exhibits protein domain specific binding; protein-containing complex binding; structural constituent of postsynaptic density; INVOLVED IN aggresome assembly; modulation of chemical synaptic transmission; protein localization to synapse; PARTICIPATES IN glutamate signaling path way; ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse; postsynaptic density, intracellular component; postsynaptic membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 117304144 | 118173463 | Rat | 141 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620224 | Dlgap2 | DLG associated protein 2 | ENCODES a protein that exhibits protein domain specific binding; INVOLVED IN modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN dendrite; dendritic spine; glutamatergic synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride | 16 | 81489059 | 82198693 | Rat | 88 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 708349 | Dlgap3 | DLG associated protein 3 | ENCODES a protein that exhibits molecular adaptor activity; PDZ domain binding; protein domain specific binding; INVOLVED IN protein-containing complex assembly; modification of postsynaptic structure (ortholog); modulation of chemical synaptic transmission (ort holog); FOUND IN dendritic spine; neuronal cell body; postsynaptic density; INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; ammonium chloride | 5 | 144776414 | 144847097 | Rat | 82 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 708350 | Dlgap4 | DLG associated protein 4 | ENCODES a protein that exhibits protein domain specific binding; INVOLVED IN modification of postsynaptic structure (ortholog); regulation of synapse maturation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN dendrite; neuronal cell body; cholinergic synapse (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl | 3 | 165584271 | 165731868 | Rat | 142 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620179 | Gnpat | glyceronephosphate O-acyltransferase | ENCODES a protein that exhibits catalytic activity (ortholog); glycerone-phosphate O-acyltransferase activity (ortholog); INVOLVED IN response to fatty acid; response to nutrient; response to starvation; PARTICIPATES IN plasmalogen biosynthetic pathway; plasmalogen metabolic pathway; glycerophosphol ipid metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol | 19 | 69719707 | 69746244 | Rat | 123 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 62038 | Dctn1 | dynactin subunit 1 | ENCODES a protein that exhibits identical protein binding; microtubule binding; molecular adaptor activity; INVOLVED IN axonal transport (ortholog); centriole-centriole cohesion (ortholog); cholesterol homeostasis (ortholog); PARTICIPATES IN mitochondria transpo rt pathway; N-cadherin signaling pathway; Huntington's disease pathway; ASSOCIATED WITH synucleinopathy; amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); FOUND IN cytoplasmic dynein complex; cell cortex (ortholog); cell leading edge (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 4 | 117228722 | 117261528 | Rat | 256 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 621766 | Dapk3 | death-associated protein kinase 3 | ENCODES a protein that exhibits ATP binding; DNA-binding transcription factor binding; kinase activity; INVOLVED IN apoptotic process; intracellular signal transduction; neuron differentiation; PARTICIPATES IN urinary bladder cancer pathway; FOUND IN actin filament; membrane raft; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol | 7 | 9174903 | 9183272 | Rat | 230 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620457 | Stk17b | serine/threonine kinase 17b | ENCODES a protein that exhibits ATP binding; protein kinase activity; protein serine/threonine kinase activity; INVOLVED IN apoptotic process; intracellular signal transduction; programmed cell death; FOUND IN actin cytoskeleton; nucleus; nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3 ,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid | 9 | 62801912 | 62832511 | Rat | 181 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305339 | Dap3 | death associated protein 3 | ENCODES a protein that exhibits GTPase activity (ortholog); structural constituent of ribosome (ortholog); INVOLVED IN apoptotic mitochondrial changes (ortholog); mitochondrial translation (ortholog); PARTICIPATES IN Trail mediated signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Perr ault Syndrome 1 (ortholog); Perrault syndrome 7 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 2 | 176617151 | 176645293 | Rat | 95 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1311629 | Dapk1 | death associated protein kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); calcium/calmodulin-dependent protein kinase activity (ortholog); calmodulin binding (ortholog); INVOLVED IN apoptotic process (ortholog); apoptotic signaling pathway (ortholog); cellular response to hydroperoxide (ortholog); PARTICIPATES IN typ e II interferon signaling pathway; urinary bladder cancer pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); adenocarcinoma (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); DAPK1-calmodulin complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17beta-estradiol | 17 | 3935826 | 4096858 | Rat | 319 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304708 | Dapk2 | death-associated protein kinase 2 | ENCODES a protein that exhibits ATP binding (ortholog); calmodulin binding (ortholog); identical protein binding (ortholog); INVOLVED IN anoikis (ortholog); intracellular signal transduction (ortholog); neutrophil migration (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); colorec tal cancer (ortholog); Hepatomegaly (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 75601621 | 75720619 | Rat | 148 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1309610 | Dapl1 | death associated protein-like 1 | INVOLVED IN cell population proliferation (ortholog); gene expression (ortholog); negative regulation of CD8-positive, alpha-beta T cell activation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 3 | 64369734 | 64389677 | Rat | 60 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310189 | Dapp1 | dual adaptor of phosphotyrosine and 3-phosphoinositides 1 | ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; B cell receptor signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); oste oarthritis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 2 | 229099319 | 229148868 | Rat | 84 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307151 | Plekhm3 | pleckstrin homology domain containing M3 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN myoblast differentiation (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; bromobenzene | 9 | 73659998 | 73819079 | Rat | 75 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1359238 | Hcst | hematopoietic cell signal transducer | ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding (ortholog); protein-macromolecule adaptor activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN natural killer cell mediated cytotoxicity (ortholog); positive regulation of p hosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein phosphorylation (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 94804429 | 94806661 | Rat | 74 | old_gene_name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303081 | Tyrobp | transmembrane immune signaling adaptor Tyrobp | ENCODES a protein that exhibits identical protein binding (ortholog); molecular adaptor activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); amyloid-beta clearance (ortholog); apoptotic cell c learance (ortholog); ASSOCIATED WITH rheumatoid arthritis; Desbuquois dysplasia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 94800372 | 94804307 | Rat | 234 | name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 631426 | Atp5mk | ATP synthase membrane subunit K | ASSOCIATED WITH mitochondrial complex V (ATP synthase) deficiency nuclear type 6 (ortholog); FOUND IN proton-transporting ATP synthase complex; mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 255915255 | 255922185 | Rat | 83 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735029 | Dele1 | DAP3 binding cell death enhancer 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN cellular response to stress (ortholog); DNA damage response (ortholog); extrinsic apoptotic signaling pathway via death domain receptors (ortholog); FOUND IN cytosol (ortholog); mitochondrial inner membrane (ortholog); mitochondrial outer membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | 18 | 30325369 | 30349285 | Rat | 90 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9203006 | Atp5mk-ps2 | ATP synthase membrane subunit K, pseudogene 2 | | 10 | 86708854 | 86709185 | Rat | | old_gene_name , ensembl_full_name | gene, pseudo, INFERRED [RefSeq] |
| 40981180 | LOC120094339 | ATP synthase membrane subunit DAPIT, mitochondrial-like | | 8 | 74434571 | 74441263 | Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 1564008 | Dact1 | dishevelled-binding antagonist of beta-catenin 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); delta-catenin binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN canonical Wnt signaling pathway (ortholog); dendrite morphogenesis (ortholog); embryonic hindgut morphogenesis (ortholog); ASSOCIATED WITH Axenfeld-R ieger syndrome (ortholog); Colorectal Neoplasms (ortholog); Townes-Brocks syndrome (ortholog); FOUND IN beta-catenin destruction complex (ortholog); cytoplasm (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil | 6 | 95526645 | 95538625 | Rat | 191 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310742 | Dact2 | dishevelled-binding antagonist of beta-catenin 2 | ENCODES a protein that exhibits beta-catenin binding (ortholog); delta-catenin binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN epithelial cell morphogenesis (ortholog); hematopoietic progenitor cell differentiation (ortholog); inner medullary collecting duct development (ortholo g); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Liver Neoplasms (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 1 | 63854182 | 63864153 | Rat | 126 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1563892 | Dact3 | dishevelled-binding antagonist of beta-catenin 3 | ENCODES a protein that exhibits delta-catenin binding (ortholog); identical protein binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of cell growth (ortholog); negative regulation of epithelial to mesenchymal transition (ortholog); ASSOCIATED WITH intellectual disability (ortholog); polycystic ovary syndrome (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH flusilazole; furan; glyphosate | 1 | 86674989 | 86686722 | Rat | 77 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9281539 | Atp5mkl1 | ATP synthase membrane subunit K like 1 | FOUND IN mitochondrial membrane (inferred) | 10 | 42712118 | 42712487 | Rat | 1 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1566388 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits miRNA binding (ortholog); translation repressor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); G1/S transition of mitotic c ell cycle (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 8 | 123076499 | 123129016 | Rat | 98 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |