| 620436 | Cga | glycoprotein hormones, alpha polypeptide | ENCODES a protein that exhibits follicle-stimulating hormone activity (ortholog); hormone activity (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); developmental growth (ortholog); follicle-stimulating hormone secretion (ortholog); PARTICIPATES IN follicle-stimulating hormon e signaling pathway; luteinizing hormone signaling pathway; autoimmune thyroiditis pathway; ASSOCIATED WITH adrenal gland disease (ortholog); atrial fibrillation (ortholog); breast cancer (ortholog); FOUND IN extracellular space (ortholog); follicle-stimulating hormone complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 54283109 | 54295464 | Rat | 243 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2338 | Chga | chromogranin A | INVOLVED IN negative regulation of cellular process; ovulation cycle; positive regulation of cAMP/PKA signal transduction; PARTICIPATES IN G protein mediated signaling pathway; ASSOCIATED WITH hypertension; basal cell carcinoma (ortholog); end stage renal disease (ortholog); FOUND IN chromaffin gran ule; extracellular space; neuronal dense core vesicle; INTERACTS WITH (S)-nicotine; 6-propyl-2-thiouracil; ammonium chloride | 6 | 127460895 | 127472238 | Rat | 177 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11517013 | Trnas-cga1 | transfer RNA serine (anticodon CGA) 1 | This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104). | 7 | 1465651 | 1465732 | Rat | | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, trna, MODEL [RefSeq] |
| 11393487 | Trnas-cga2 | transfer RNA serine (anticodon CGA) 2 | This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104). | 10 | 54314790 | 54314871 | Rat | | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, trna, MODEL [RefSeq] |
| 11463849 | Trnas-cga3 | transfer RNA serine (anticodon CGA) 3 | This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104). | 17 | 47197051 | 47197132 | Rat | | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, trna, MODEL [RefSeq] |
| 1586939 | Cgas | cyclic GMP-AMP synthase | ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP synthase activity (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); cellular response to exogenous dsRNA (ortholog); cGAS/STING signaling pathway (ortholog); FOUND IN cyt oplasm (ortholog); cytosol (ortholog); nuclear body (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 88172559 | 88187538 | Rat | 212 | symbol , PhenoGen , description | gene, protein-coding, MODEL [RefSeq] |
| 3693 | Slc18a1 | solute carrier family 18 member A1 | ENCODES a protein that exhibits enzyme binding; monoamine:proton antiporter activity; serotonin:sodium:chloride symporter activity; INVOLVED IN cellular response to lithium ion; negative regulation of serotonin uptake; positive regulation of dopamine secretion; PARTICIPATES IN Parkinson's disease pa thway; ASSOCIATED WITH bipolar disorder (ortholog); schizophrenia (ortholog); von Hippel-Lindau disease (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); secretory granule membrane (ortholog); synapse (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 25408485 | 25453786 | Rat | 112 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 3938 | Ugt8 | UDP glycosyltransferase 8 | ENCODES a protein that exhibits N-acylsphingosine galactosyltransferase activity; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity; INVOLVED IN galactosylceramide biosynthetic process; response to immobilization stress; cytoskeleton organization (ortholog); PARTICIPATES IN Fabr y disease pathway; Gaucher's disease pathway; Krabbe disease pathway; FOUND IN endoplasmic reticulum; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 2 | 216938884 | 217007167 | Rat | 127 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 13782372 | Cacna1f csnb | calcium voltage-gated channel subunit alpha1 F; congenital stationary night blindness mutant | ASSOCIATED WITH abnormal b-wave amplitude; abnormal cone electrophysiology; abnormal mechanical nociception; ASSOCIATED WITH congenital stationary night blindness | | | | Rat | 10 | description | gene, allele |
| 126925980 | Ercc6em1Cgen | ERCC excision repair 6, chromatin remodeling factor; CRISPR/Cas9 induced mutant 1, Cgen | ASSOCIATED WITH abnormal base-excision repair; abnormal cerebellar cortex morphology; astrocytosis; ASSOCIATED WITH Cockayne syndrome B | | | | Rat | 7 | description | gene, allele |
| 1562552 | Sting1 | stimulator of interferon response cGAMP interactor 1 | ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding; cyclic-di-GMP binding (ortholog); identical protein binding (ortholog); INVOLVED IN positive regulation of type I interferon production; activation of innate immune response (ortholog); antiviral innate immune response (ortholog); ASSOCIA TED WITH Animal Toxoplasmosis (ortholog); brucellosis (ortholog); Chediak-Higashi syndrome (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; arsane | 18 | 27606196 | 27612544 | Rat | 310 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359277 | Smpdl3a | sphingomyelin phosphodiesterase, acid-like 3A | ENCODES a protein that exhibits phosphoric diester hydrolase activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN negative regulation of cGAS/STING signaling pathway (ortholog); nucleoside triphosphate catabolic process (ortholog); sphing omyelin catabolic process (ortholog); ASSOCIATED WITH endometriosis (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 20 | 37679004 | 37701979 | Rat | 164 | old_gene_name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310617 | Aars2 | alanyl-tRNA synthetase 2, mitochondrial | ENCODES a protein that exhibits alanine-tRNA ligase activity (ortholog); peptide lactyltransferase (ATP-dependent) activity (ortholog); INVOLVED IN mitochondrial alanyl-tRNA aminoacylation (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); PARTICIPATES IN alanine metabolic p athway; lactic acidosis pathway; primary hyperoxaluria type 1 pathway; ASSOCIATED WITH combined oxidative phosphorylation deficiency (ortholog); combined oxidative phosphorylation deficiency 8 (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; aconitine | 9 | 22981880 | 22993536 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311195 | Lyplal1 | lysophospholipase-like 1 | ENCODES a protein that exhibits hydrolase activity, acting on ester bonds (ortholog); lipase activity (ortholog); palmitoyl-(protein) hydrolase activity (ortholog); INVOLVED IN negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of Golgi to plasma membrane protein tra nsport (ortholog); protein depalmitoylation (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 100158060 | 100189339 | Rat | 105 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305617 | Marchf5 | membrane associated ring-CH-type finger 5 | ENCODES a protein that exhibits GTPase binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of cytoplasmic pattern recognition receptor signaling pathway (ortholog); positive regulation of cGAS/STING signaling pathway (ortholog); positive regulation of mi tochondrial fission (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrial outer membrane (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 1 | 244343674 | 244365160 | Rat | 112 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 127284866 | Nppcem1Kyo | natriuretic peptide C; ZFN induced mutant 1, Kyo | Selected ZFNs were designed to target exon 1 of rat Nppc, which encodes the N-terminus of natriuretic peptide precursor C (target sequence: CGAAGCCAAGCCCGGGACaccaccGAAGGTGGGTGCTGTCGCG; nucleotides 179 - 221, NC_005108.4). This allele ( delta 6) was deduced to ge nerate a two a.a. deletion (a.a. 28 and 29, Pro and Pro, NP_446202, at nucleotides 198 - 203, NM_053750.1). | | | | Rat | | description | gene, allele |
| 127284869 | Nppcem2Kyo | natriuretic peptide C; ZFN induced mutant 2 , Kyo | Selected ZFNs were designed to target exon 1 of rat Nppc, which encodes the N-terminus of natriuretic peptide precursor C (target sequence: CGAAGCCAAGCCCGGGACaccaccGAAGGTGGGTGCTGTCGCG; nucleotides 179 - 221, NC_005108.4). This allele ( delta 9) was deduced to ge nerate one amino-acid substitution (a.a. 26, from Gly to Ala, NP_446202, at nucleotides 192 - 194, NM_053750.1) and a three amino-acid deletion (a.a. 27 - 29, Thr, Pro and Pro, NP_446202, at nucleotides 193 - 201, NM_053750.1), within the N-terminal portion of the full-length Nppc | | | | Rat | | description | gene, allele |
| 127284871 | Nppcem3Kyo | natriuretic peptide C; ZFN induced mutant 3, Kyo | ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length | | | | Rat | 10 | description | gene, allele |
| 127284873 | Nppcem4Kyo | natriuretic peptide C; ZFN induced mutant 4, Kyo | ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length | | | | Rat | 8 | description | gene, allele |
| 1309626 | Pcbp2 | poly(rC) binding protein 2 | ENCODES a protein that exhibits C-rich single-stranded DNA binding (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN chromatin looping (ortholog); IRES-dependent viral translational initiation (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); PARTIC IPATES IN iron homeostasis pathway; iron storage pathway; FOUND IN postsynaptic density; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 7 | 135483702 | 135508254 | Rat | 146 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708460 | Ppp6c | protein phosphatase 6, catalytic subunit | ENCODES a protein that exhibits protein serine/threonine phosphatase activity; INVOLVED IN protein dephosphorylation; negative regulation of cGAS/STING signaling pathway (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog) ; melanoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; ammonium chloride | 3 | 43339521 | 43371807 | Rat | 72 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628854 | Rnf39 | ring finger protein 39 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of cytoplasmic pattern recognition receptor signaling pathway (ortholog); positive regulation of cGAS/STING signaling pathway (ortholog); protein K63-linked ubiquitination (ortholog); ASSOCI ATED WITH cholangiocarcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 1610027 | 1615516 | Rat | 91 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310936 | Spsb3 | splA/ryanodine receptor domain and SOCS box containing 3 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of epithelial to mesenchymal transition (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic p rocess (ortholog); FOUND IN Cul5-RING ubiquitin ligase complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 14411692 | 14417357 | Rat | 77 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309334 | Zdhhc18 | zDHHC palmitoyltransferase 18 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); INVOLVED IN intracellular protein localization (ortholog); negative regulation of cGAS/STING signaling pathway (ortholog); negative regulation of innate immune respo nse (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 151105303 | 151143843 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561389 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A | X | 132230243 | 132266139 | Rat | 105 | description | gene, protein-coding, PROVISIONAL [RefSeq] |