| 620588 | Cd14 | CD14 molecule | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); lipopolysaccharide immune receptor activity (ortholog); lipoteichoic acid binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide; positive regulation of cytokine production; response to electrical stimulus; PARTI CIPATES IN cardiovascular system disease pathway; innate immune response pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH Acute Liver Failure; Burns; Cerebral Hemorrhage; FOUND IN cell surface; extracellular space; external side of plasma membrane (ortholog); INTERACTS WITH (S)-colchicine; 17alpha-ethynylestradiol; 17beta-estradiol | 18 | 28609558 | 28611409 | Rat | 538 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12790606 | Cd14em1Mcwi | CD14 molecule; CRISPR/Cas9 system induced mutant 1, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 2-bp deletion in the exon 2 of rat Cd14 gene | | | | Rat | | symbol , name , description , old_gene_symbol | gene, allele |
| 12790611 | Cd14em2Mcwi | CD14 molecule; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a net 7-bp deletion in the rat Cd14 gene. | | | | Rat | | symbol , name , description , old_gene_symbol | gene, allele |
| 2493 | Ace | angiotensin I converting enzyme | ENCODES a protein that exhibits heterocyclic compound binding; metallopeptidase activity; peptidase activity; INVOLVED IN angiogenesis involved in coronary vascular morphogenesis; animal organ regeneration; bradykinin catabolic process; PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angi otensin cascade pathway; angiotensin II signaling pathway; ASSOCIATED WITH decreased angiotensin I-converting enzyme activity; increased angiotensin I-converting enzyme activity; ASSOCIATED WITH abdominal aortic aneurysm; Acute Hepatitis; acute kidney failure; FOUND IN basal plasma membrane; brush border membrane; extracellular space; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (R)-lipoic acid | 10 | 91410129 | 91430246 | Rat | 875 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620463 | Mcam | melanoma cell adhesion molecule | INVOLVED IN positive regulation of cell migration; angiogenesis (ortholog); glomerular filtration (ortholog); ASSOCIATED WITH Emphysema; Hypoglossal Nerve Injuries; impotence; FOUND IN extracellular space; external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta -estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 8 | 53376225 | 53384407 | Rat | 207 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 3284 | Pdgfra | platelet derived growth factor receptor alpha | ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding; platelet-derived growth factor alpha-receptor activity; phospholipase C activator activity (ortholog); INVOLVED IN cellular response to fibroblast growth factor stimulus; cellular response to interleukin-1; inner ear development; PARTICIPATES IN platelet-derived growth factor signaling pathway; calcium/calcium-mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Brain Injuries; Chronic Allograft Nephropathy; chronic ulcer of skin; FOUND IN axon; cytoplasm; nucleus; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 14 | 33360027 | 33408604 | Rat | 535 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 3285 | Pdgfrb | platelet derived growth factor receptor beta | ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding; platelet-derived growth factor receptor activity; protein tyrosine kinase activity; INVOLVED IN glycosaminoglycan biosynthetic process; inner ear development; intracellular signal transduction; PARTICIPATES IN platelet-derived gr owth factor signaling pathway; sphingosine 1-phosphate signaling pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Brain Injuries; Cardiomegaly; Chronic Allograft Nephropathy; FOUND IN apical plasma membrane; cell surface; cytoplasm; INTERACTS WITH (+)-dihydromyricetin; (-)-epigallocatechin 3-gallate; (R,R,R)-alpha-tocopherol | 18 | 56770348 | 56809228 | Rat | 601 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |