| 620309 | Cap1 | cyclase associated actin cytoskeleton regulatory protein 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); ameboidal-type cell migration (ortholog); cell morphogenesis (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Neoplasm Metastasis (ortholog); osteoporosis ( ortholog); FOUND IN cortical actin cytoskeleton (ortholog); cytoplasm (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 5 | 140427265 | 140507678 | Rat | 136 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1586623 | Cap1-ps1 | cyclase associated actin cytoskeleton regulatory protein 1, pseudogene 1 | | 16 | 16200385 | 16216164 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 621808 | Park7 | Parkinsonism associated deglycase | ENCODES a protein that exhibits copper ion binding (ortholog); cupric ion binding (ortholog); cuprous ion binding (ortholog); INVOLVED IN cellular response to hypoxia; cellular response to lipopolysaccharide; maternal process involved in female pregnancy; PARTICIPATES IN transforming growth factor-b eta signaling pathway; Parkinson's disease pathway; ASSOCIATED WITH abnormal gait; abnormal motor coordination/balance; abnormal muscle tone; ASSOCIATED WITH Parkinson's disease; Parkinsonism; Pulmonary Arterial Hypertension; FOUND IN axon; endoplasmic reticulum; mitochondrion; INTERACTS WITH 1-bromopropane; 15-deoxy-Delta(12,14)-prostaglandin J2; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 166636551 | 166659825 | Rat | 541 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 619973 | Prss8 | serine protease 8 | ENCODES a protein that exhibits sodium channel regulator activity (ortholog); INVOLVED IN positive regulation of sodium ion transmembrane transport; response to mineralocorticoid; response to peptide hormone; ASSOCIATED WITH alopecia; autosomal recessive congenital ichthyosis 4B (ortholog); breast c arcinoma (ortholog); FOUND IN extracellular space; external side of plasma membrane (ortholog); membrane raft (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 191966701 | 191971271 | Rat | 163 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 70924 | Pdzk1 | PDZ domain containing 1 | ENCODES a protein that exhibits protein-containing complex binding; scavenger receptor binding; PDZ domain binding (ortholog); INVOLVED IN carnitine transmembrane transport (ortholog); in utero embryonic development (ortholog); positive regulation of protein localization to membrane (ortholog); ASSO CIATED WITH adenoid cystic carcinoma (ortholog); Breast Neoplasms (ortholog); Prostatic Neoplasms (ortholog); FOUND IN apical plasma membrane; microvillus membrane; brush border (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 187064995 | 187096348 | Rat | 184 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307801 | Cmtr1 | cap methyltransferase 1 | ENCODES a protein that exhibits methyltransferase cap1 activity (ortholog); INVOLVED IN 7-methylguanosine mRNA capping (ortholog); mRNA processing (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; at razine | 20 | 7724286 | 7784787 | Rat | 103 | old_gene_name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2074 | Ahr | aryl hydrocarbon receptor | ENCODES a protein that exhibits arachidonate omega-hydroxylase activity; nuclear receptor activity; promoter-specific chromatin binding; INVOLVED IN cellular response to 2,3,7,8-tetrachlorodibenzodioxine; cellular response to dexamethasone stimulus; cellular response to glucocorticoid stimulus; PART ICIPATES IN aryl hydrocarbon receptor signaling pathway; ASSOCIATED WITH abnormal kidney medullary ray morphology; abnormal urothelium morphology; absent ductus venosus; ASSOCIATED WITH Cardiac Fibrosis; Cardiomegaly; Chemical and Drug Induced Liver Injury; FOUND IN cytoplasm; nucleus; cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1,10-phenanthroline | 6 | 57961423 | 57998901 | Rat | 1839 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 620412 | Jup | junction plakoglobin | ENCODES a protein that exhibits protein kinase binding; protein tyrosine kinase binding; protein-containing complex binding; INVOLVED IN bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); cell adhesion (ortholog); cell migration (ortholog); PARTICIPATES IN E-cadh erin signaling pathway; N-cadherin signaling pathway; acute myeloid leukemia pathway; ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); arrhythmogenic right ventricular dysplasia 12 (ortholog); Breast Neoplasms (ortholog); FOUND IN actin cytoskeleton; adherens junction; apicolateral plasma membrane; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 10 | 85800812 | 85827881 | Rat | 374 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3663 | Mapk10 | mitogen activated protein kinase 10 | ENCODES a protein that exhibits ATP binding; JUN kinase activity; INVOLVED IN cellular hyperosmotic response; JNK cascade; JUN phosphorylation; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIAT ED WITH Alzheimer's disease (ortholog); congestive heart failure (ortholog); generalized epilepsy (ortholog); FOUND IN glutamatergic synapse; perikaryon; postsynaptic Golgi apparatus; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2-ethoxyethanol; 2-methoxyethanol | 14 | 6802247 | 7094103 | Rat | 284 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1307472 | Pkp1 | plakophilin 1 | ENCODES a protein that exhibits DNA binding (ortholog); lamin binding (ortholog); INVOLVED IN ameloblast differentiation (ortholog); desmosome assembly (ortholog); desmosome maintenance (ortholog); ASSOCIATED WITH ectodermal dysplasia (ortholog); Ectodermal Dysplasia-Skin Fragility Syndrome (ortholo g); genetic disease (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); desmosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 13 | 49861340 | 49909162 | Rat | 166 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3632 | Scn2a | sodium voltage-gated channel alpha subunit 2 | ENCODES a protein that exhibits leucine zipper domain binding; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; voltage-gated sodium channel activity; INVOLVED IN axon development; cellular response to hypoxia; cerebral cortex development; ASSOC IATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); autosomal dominant intellectual developmental disorder (ortholog); FOUND IN axon; axon initial segment; node of Ranvier; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl | 3 | 70710862 | 70845569 | Rat | 221 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3635 | Scn3a | sodium voltage-gated channel alpha subunit 3 | ENCODES a protein that exhibits calmodulin binding; voltage-gated sodium channel activity (ortholog); INVOLVED IN cellular response to antibiotic; nervous system development; response to pyrethroid; ASSOCIATED WITH Spinal Cord Injuries; complex cortical dysplasia with other brain malformations 14B ( ortholog); complex partial epilepsy (ortholog); FOUND IN axon; neuronal cell body; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 70554496 | 70666198 | Rat | 132 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 69368 | Scn9a | sodium voltage-gated channel alpha subunit 9 | ENCODES a protein that exhibits voltage-gated sodium channel activity (ortholog); INVOLVED IN behavioral response to formalin induced pain; negative regulation of action potential; action potential propagation (ortholog); ASSOCIATED WITH abnormal afterhyperpolarization; abnormal pain threshold; decr eased susceptibility to induced hypothermia; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate B (ortholog); Chronic Pain (ortholog); Congenital Indifference to Pain, Autosomal Recessive (ortholog); FOUND IN axon; axon terminus (ortholog); node of Ranvier (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 3 | 71553185 | 71701377 | Rat | 192 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1305548 | Stac2 | SH3 and cysteine rich domain 2 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of protein localization to plasma membrane (ortholog); positive regulation of voltage-gated calcium channel activity (ortholog); ASSOCIATED WITH Childhood Schizophrenia (ortholo g); High Myopia (ortholog); FOUND IN cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 83528741 | 83544583 | Rat | 84 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |