Gene: Scn2a (sodium voltage-gated channel alpha subunit 2) Rattus norvegicus
Analyze
Symbol: Scn2a
Name: sodium voltage-gated channel alpha subunit 2
Description: ENCODES a protein that exhibits leucine zipper domain binding; sodium ion binding; voltage-gated sodium channel activity; INVOLVED IN myelination; neuronal action potential; sodium ion transmembrane transport; ASSOCIATED WITH Abnormalities, Multiple (ortholog); adolescence-adult electroclinical syndrome (ortholog); autism spectrum disorder (ortholog); FOUND IN axon initial segment; intrinsic component of plasma membrane; neuron projection; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alternative product; NachII; Nav1.2; RII/RIIA; RIIA sodium channel protein; RNSCPIIR; SCN; Scn2a1; Scn2a2; ScpII; sodium channel protein brain II subunit alpha; sodium channel protein type 2 subunit alpha; sodium channel protein type II subunit alpha; sodium channel protein, brain II subunit alpha; Sodium channel voltage-gated type II alpha polypeptide; sodium channel, voltage-gated, type 2, alpha 1 polypeptide; sodium channel, voltage-gated, type 2, alpha 1 subunit; sodium channel, voltage-gated, type II, alpha 1; Sodium channel, voltage-gated, type II, alpha polypeptide; sodium channel, voltage-gated, type II, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.2
Orthologs:
Is Marker For: QTLs:   BpQTLcluster4   Tsu1   Hrtrt17  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0351,687,910 - 51,822,008 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0358,322,640 - 58,456,658 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4347,588,413 - 47,722,800 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1347,484,784 - 47,619,172 (+)NCBI
Celera349,896,043 - 50,030,402 (+)NCBI
Cytogenetic Map3q21NCBImapview
RH 3.4 Map3613.5RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scn2a
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3632
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE