Klhl2 (kelch-like family member 2) - Rat Genome Database

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Gene: Klhl2 (kelch-like family member 2) Rattus norvegicus
Analyze
Symbol: Klhl2
Name: kelch-like family member 2
RGD ID: 1306388
Description: Predicted to enable actin binding activity; identical protein binding activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in protein ubiquitination. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KLHL2 (kelch like family member 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kelch-like 2, Mayven; kelch-like 2, Mayven (Drosophila); kelch-like protein 2; LOC290692; LOC364547; mayven; RGD1564686; similar to Klhl2 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81629,627,171 - 29,739,782 (+)NCBIGRCr8
mRatBN7.21624,860,744 - 24,973,348 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1624,860,667 - 24,973,341 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01626,755,246 - 26,852,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1626,739,389 - 26,852,179 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01626,622,472 - 26,731,058 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41626,634,400 - 26,690,756 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11626,648,722 - 26,691,115 (+)NCBI
Celera1624,962,535 - 25,057,740 (+)NCBICelera
Cytogenetic Map16p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
protein ubiquitination  (IEA,ISO,ISS)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10397770   PMID:21549840   PMID:25416956   PMID:31515488  


Genomics

Comparative Map Data
Klhl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81629,627,171 - 29,739,782 (+)NCBIGRCr8
mRatBN7.21624,860,744 - 24,973,348 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1624,860,667 - 24,973,341 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01626,755,246 - 26,852,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1626,739,389 - 26,852,179 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01626,622,472 - 26,731,058 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41626,634,400 - 26,690,756 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11626,648,722 - 26,691,115 (+)NCBI
Celera1624,962,535 - 25,057,740 (+)NCBICelera
Cytogenetic Map16p13NCBI
KLHL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384165,207,561 - 165,323,156 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4165,207,561 - 165,323,156 (+)EnsemblGRCh38hg38GRCh38
GRCh374166,128,713 - 166,244,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364166,348,238 - 166,463,749 (+)NCBINCBI36Build 36hg18NCBI36
Build 344166,486,395 - 166,601,903NCBI
Celera4163,459,950 - 163,579,735 (+)NCBICelera
Cytogenetic Map4q32.3NCBI
HuRef4161,880,568 - 161,996,120 (+)NCBIHuRef
CHM1_14166,105,246 - 166,220,767 (+)NCBICHM1_1
T2T-CHM13v2.04168,553,548 - 168,669,151 (+)NCBIT2T-CHM13v2.0
Klhl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,192,707 - 65,302,821 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl865,192,709 - 65,302,669 (-)EnsemblGRCm39 Ensembl
GRCm38864,739,673 - 64,850,169 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,739,675 - 64,850,017 (-)EnsemblGRCm38mm10GRCm38
MGSCv37867,335,578 - 67,373,716 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36867,631,868 - 67,672,057 (-)NCBIMGSCv36mm8
Celera867,303,934 - 67,417,078 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map832.3NCBI
Klhl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540340,012,453 - 40,094,853 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540340,013,840 - 40,094,853 (-)NCBIChiLan1.0ChiLan1.0
KLHL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23162,956,665 - 163,072,228 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14163,314,357 - 163,430,083 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04157,402,905 - 157,518,639 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14169,572,832 - 169,602,304 (+)NCBIpanpan1.1PanPan1.1panPan2
KLHL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11561,204,371 - 61,289,020 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1561,204,363 - 61,298,581 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1561,500,904 - 61,598,362 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01562,054,076 - 62,151,403 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1562,054,088 - 62,151,392 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11561,235,595 - 61,332,798 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01561,279,065 - 61,376,285 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01561,672,882 - 61,770,206 (+)NCBIUU_Cfam_GSD_1.0
Klhl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494317,804,579 - 17,886,216 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936555684,093 - 766,006 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936555684,300 - 765,934 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl843,749,423 - 43,870,923 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1843,749,423 - 43,871,011 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2845,677,143 - 45,798,587 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17111,569,027 - 111,684,065 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7111,569,125 - 111,684,879 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603791,412,273 - 91,534,401 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475811,649,396 - 11,765,961 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475811,649,603 - 11,765,636 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhl2
724 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:79
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000047223
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat

Markers in Region
D16Mgh9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,891,565 - 24,891,815 (+)MAPPERmRatBN7.2
Rnor_6.01626,770,359 - 26,770,607NCBIRnor6.0
Rnor_5.01626,650,677 - 26,650,925UniSTSRnor5.0
RGSC_v3.41626,915,620 - 26,915,869RGDRGSC3.4
RGSC_v3.41626,915,621 - 26,915,869UniSTSRGSC3.4
RGSC_v3.11626,915,619 - 26,915,867RGD
Celera1624,977,129 - 24,977,377UniSTS
RH 3.4 Map16309.4UniSTS
RH 3.4 Map16309.4RGD
RH 2.0 Map16341.5RGD
Cytogenetic Map16p13UniSTS
RH131362  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,972,309 - 24,972,520 (+)MAPPERmRatBN7.2
Rnor_6.01626,851,098 - 26,851,308NCBIRnor6.0
Rnor_5.01626,730,024 - 26,730,234UniSTSRnor5.0
RGSC_v3.41626,689,931 - 26,690,141UniSTSRGSC3.4
Celera1625,056,704 - 25,056,914UniSTS
Cytogenetic Map16p13UniSTS
RH132283  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,973,083 - 24,973,303 (+)MAPPERmRatBN7.2
Rnor_6.01626,851,872 - 26,852,091NCBIRnor6.0
Rnor_5.01626,730,798 - 26,731,017UniSTSRnor5.0
RGSC_v3.41626,690,705 - 26,690,924UniSTSRGSC3.4
Celera1625,057,478 - 25,057,697UniSTS
Cytogenetic Map16p13UniSTS
BF403575  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,906,552 - 24,906,642 (+)MAPPERmRatBN7.2
Rnor_6.01626,785,355 - 26,785,444NCBIRnor6.0
Rnor_5.01626,665,673 - 26,665,762UniSTSRnor5.0
RGSC_v3.41626,899,764 - 26,899,853UniSTSRGSC3.4
Celera1624,992,143 - 24,992,232UniSTS
RH 3.4 Map16311.2UniSTS
Cytogenetic Map16p13UniSTS
RH138247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,867,281 - 24,867,468 (+)MAPPERmRatBN7.2
Rnor_6.01626,745,517 - 26,745,703NCBIRnor6.0
Rnor_5.01626,627,131 - 26,627,317UniSTSRnor5.0
RGSC_v3.41626,943,657 - 26,943,843UniSTSRGSC3.4
Celera1624,952,904 - 24,953,090UniSTS
RH 3.4 Map16312.8UniSTS
Cytogenetic Map16p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 24 33 17 19 17 74 35 33 11
Low 19 24 24 24 8 11 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000047223   ⟹   ENSRNOP00000049839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1624,860,667 - 24,973,341 (+)Ensembl
Rnor_6.0 Ensembl1626,739,389 - 26,852,179 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096451   ⟹   ENSRNOP00000082044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1624,876,683 - 24,965,485 (+)Ensembl
RefSeq Acc Id: NM_001419565   ⟹   NP_001406494
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81629,627,237 - 29,739,780 (+)NCBI
mRatBN7.21624,860,744 - 24,973,346 (+)NCBI
RefSeq Acc Id: XM_039095083   ⟹   XP_038951011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81629,627,171 - 29,739,782 (+)NCBI
mRatBN7.21624,860,763 - 24,973,348 (+)NCBI
RefSeq Acc Id: XM_063275213   ⟹   XP_063131283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81629,655,088 - 29,739,782 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000049839   ⟸   ENSRNOT00000047223
RefSeq Acc Id: XP_038951011   ⟸   XM_039095083
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000082044   ⟸   ENSRNOT00000096451
RefSeq Acc Id: NP_001406494   ⟸   NM_001419565
- UniProtKB: F1LZF0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063131283   ⟸   XM_063275213
- Peptide Label: isoform X2
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LZF0-F1-model_v2 AlphaFold F1LZF0 1-593 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306388 AgrOrtholog
BioCyc Gene G2FUF-11632 BioCyc
Ensembl Genes ENSRNOG00000029441 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055013284 UniProtKB/Swiss-Prot
  ENSRNOG00060015283 UniProtKB/Swiss-Prot
  ENSRNOG00065005032 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000047223 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000047223.6 UniProtKB/Swiss-Prot
  ENSRNOT00000096451.1 UniProtKB/TrEMBL
  ENSRNOT00055022799 UniProtKB/Swiss-Prot
  ENSRNOT00060026254 UniProtKB/Swiss-Prot
  ENSRNOT00065007369 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KLHL2_BTB/POZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 290692 ENTREZGENE
PANTHER ACTIN-BINDING PROTEIN IPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KELCH PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klhl2 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KELCHREPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029441 RatGTEx
  ENSRNOG00055013284 RatGTEx
  ENSRNOG00060015283 RatGTEx
  ENSRNOG00065005032 RatGTEx
SMART BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MY35_RAT UniProtKB/TrEMBL
  A0A8I5ZTS8_RAT UniProtKB/TrEMBL
  F1LZF0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Klhl2  kelch-like family member 2  RGD1564686  similar to Klhl2 protein  Data merged from RGD:1564686 737654 PROVISIONAL
2013-02-06 Klhl2  kelch-like family member 2  Klhl2  kelch-like 2, Mayven (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl2  kelch-like 2, Mayven (Drosophila)   Klhl2_predicted  kelch-like 2, Mayven (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2008-04-30 RGD1564686  similar to Klhl2 protein   RGD1564686_predicted  similar to Klhl2 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564686_predicted  similar to Klhl2 protein (predicted)  LOC364547  similar to Klhl2 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC364547  similar to Klhl2 protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Klhl2_predicted  kelch-like 2, Mayven (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED