Zfp36l1 (ZFP36 ring finger protein like 1) - Rat Genome Database

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Gene: Zfp36l1 (ZFP36 ring finger protein like 1) Chinchilla lanigera
Analyze
Symbol: Zfp36l1
Name: ZFP36 ring finger protein like 1
RGD ID: 9027629
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); mRNA 3'-UTR AU-rich region binding (ortholog); mRNA binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); apoptotic process (ortholog); cell population proliferation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ZFP36 ring finger protein-like 1; zinc finger protein 36, C3H1 type-like 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554661,541,323 - 1,546,617 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,541,367 - 1,546,617 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3'-UTR-mediated mRNA destabilization  (ISO)
apoptotic process  (ISO)
cell population proliferation  (ISO)
cellular response to cAMP  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to glucocorticoid stimulus  (ISO)
cellular response to hypoxia  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to peptide hormone stimulus  (ISO)
cellular response to raffinose  (ISO)
cellular response to salt stress  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to tumor necrosis factor  (ISO)
chorio-allantoic fusion  (ISO)
embryonic organ development  (ISO)
ERK1 and ERK2 cascade  (ISO)
heart development  (ISO)
MAPK cascade  (ISO)
mesendoderm development  (ISO)
mRNA catabolic process  (ISO)
mRNA transport  (ISO)
multicellular organism growth  (ISO)
negative regulation of erythrocyte differentiation  (ISO)
negative regulation of mitotic cell cycle phase transition  (ISO)
neural tube development  (ISO)
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (ISO)
nuclear-transcribed mRNA catabolic process, deadenylation-independent decay  (ISO)
p38MAPK cascade  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of intracellular mRNA localization  (ISO)
positive regulation of monocyte differentiation  (ISO)
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (ISO)
proepicardium development  (ISO)
regulation of B cell differentiation  (ISO)
regulation of gene expression  (ISO)
regulation of keratinocyte apoptotic process  (ISO)
regulation of keratinocyte differentiation  (ISO)
regulation of keratinocyte proliferation  (ISO)
regulation of mRNA 3'-end processing  (ISO)
regulation of mRNA stability  (ISO)
regulation of myoblast differentiation  (ISO)
regulation of stem cell proliferation  (ISO)
regulation of translation  (ISO)
response to wounding  (ISO)
spongiotrophoblast layer development  (ISO)
T cell differentiation in thymus  (ISO)
vasculogenesis  (ISO)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zfp36l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554661,541,323 - 1,546,617 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,541,367 - 1,546,617 (+)NCBIChiLan1.0ChiLan1.0
ZFP36L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381468,787,655 - 68,796,243 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1468,787,660 - 68,796,253 (-)EnsemblGRCh38hg38GRCh38
GRCh371469,254,372 - 69,262,960 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361468,324,128 - 68,329,538 (-)NCBINCBI36Build 36hg18NCBI36
Build 341468,324,127 - 68,329,538NCBI
Celera1449,313,123 - 49,318,532 (-)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1449,422,410 - 49,430,997 (-)NCBIHuRef
CHM1_11469,192,821 - 69,201,405 (-)NCBICHM1_1
T2T-CHM13v2.01462,994,521 - 63,003,244 (-)NCBIT2T-CHM13v2.0
Zfp36l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391280,154,534 - 80,159,787 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1280,154,528 - 80,159,787 (-)EnsemblGRCm39 Ensembl
GRCm381280,107,760 - 80,113,013 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1280,107,754 - 80,113,013 (-)EnsemblGRCm38mm10GRCm38
MGSCv371281,208,747 - 81,214,000 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361281,026,600 - 81,031,853 (-)NCBIMGSCv36mm8
Celera1281,572,651 - 81,577,898 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1236.46NCBI
Zfp36l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86104,663,396 - 104,669,815 (-)NCBIGRCr8
mRatBN7.2698,930,705 - 98,935,748 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,930,718 - 98,935,748 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx699,353,158 - 99,358,199 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0699,652,241 - 99,657,282 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0699,039,210 - 99,044,249 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06103,308,032 - 103,313,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6103,308,045 - 103,313,074 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,987,360 - 115,992,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46103,119,555 - 103,124,576 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16103,123,010 - 103,128,032 (-)NCBI
Celera697,294,425 - 97,299,423 (-)NCBICelera
Cytogenetic Map6q24NCBI
ZFP36L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21569,902,452 - 69,911,122 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11469,118,962 - 69,127,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01449,372,058 - 49,379,116 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11468,247,341 - 68,255,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1468,247,347 - 68,255,805 (-)Ensemblpanpan1.1panPan2
ZFP36L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1842,663,287 - 42,668,665 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl842,664,223 - 42,668,514 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha842,352,777 - 42,358,311 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0842,893,323 - 42,898,832 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl842,893,325 - 42,898,755 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1842,507,658 - 42,513,193 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0842,582,437 - 42,587,961 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0842,941,809 - 42,947,345 (-)NCBIUU_Cfam_GSD_1.0
Zfp36l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864062,140,623 - 62,145,363 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649512,045,377 - 12,051,536 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649512,045,679 - 12,050,737 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFP36L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl792,490,017 - 92,495,554 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1792,490,069 - 92,495,864 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2798,803,589 - 98,809,023 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFP36L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12446,000,222 - 46,005,455 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2445,999,623 - 46,006,218 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605334,233,922 - 34,240,910 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfp36l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473432,251,114 - 32,257,211 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473432,251,100 - 32,256,458 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005302   ⟹   ENSCLAP00000005206
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554661,541,323 - 1,546,617 (+)Ensembl
RefSeq Acc Id: XM_005399050   ⟹   XP_005399107
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554661,541,367 - 1,546,617 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005399107 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005206
  ENSCLAP00000005206.1
Reference Protein Sequences
RefSeq Acc Id: XP_005399107   ⟸   XM_005399050
- UniProtKB: A0A8C2YKE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005206   ⟸   ENSCLAT00000005302
Protein Domains
C3H1-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005302 ENTREZGENE
  ENSCLAT00000005302.1 UniProtKB/TrEMBL
Gene3D-CATH Zinc finger, CCCH-type UniProtKB/TrEMBL
InterPro Tis11B_N UniProtKB/TrEMBL
  ZFP36-like UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
NCBI Gene Zfp36l1 ENTREZGENE
PANTHER MRNA DECAY ACTIVATOR PROTEIN ZFP36L1 UniProtKB/TrEMBL
  PTHR12547 UniProtKB/TrEMBL
Pfam Tis11B_N UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
PROSITE ZF_C3H1 UniProtKB/TrEMBL
SMART ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF90229 UniProtKB/TrEMBL
UniProt A0A8C2YKE8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Zfp36l1  ZFP36 ring finger protein like 1    ZFP36 ring finger protein-like 1  Symbol and/or name change 5135510 APPROVED