Tlr1 (toll like receptor 1) - Rat Genome Database

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Gene: Tlr1 (toll like receptor 1) Chinchilla lanigera
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Symbol: Tlr1
Name: toll like receptor 1
RGD ID: 9021853
Description: ENCODES a protein that exhibits identical protein binding (ortholog); lipopeptide binding (ortholog); Toll-like receptor 2 binding (ortholog); INVOLVED IN cellular response to triacyl bacterial lipopeptide (ortholog); defense response (ortholog); detection of triacyl bacterial lipopeptide (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; ASSOCIATED WITH aspergillosis (ortholog); asthma (ortholog); Brain Injuries (ortholog); FOUND IN Golgi apparatus (ortholog); membrane raft (ortholog); receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: toll-like receptor 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554438,447,956 - 8,450,382 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554438,442,419 - 8,450,318 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tlr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554438,447,956 - 8,450,382 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554438,442,419 - 8,450,318 (+)NCBIChiLan1.0ChiLan1.0
TLR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38438,787,569 - 38,805,644 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl438,790,677 - 38,856,817 (-)EnsemblGRCh38hg38GRCh38
GRCh37438,797,876 - 38,806,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36438,474,271 - 38,482,807 (-)NCBINCBI36Build 36hg18NCBI36
Build 34438,620,443 - 38,628,978NCBI
Cytogenetic Map4p14NCBI
HuRef438,122,243 - 38,130,779 (-)NCBIHuRef
CHM1_1438,797,457 - 38,805,993 (-)NCBICHM1_1
T2T-CHM13v2.0438,758,769 - 38,775,212 (-)NCBIT2T-CHM13v2.0
Tlr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,082,023 - 65,090,945 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,082,022 - 65,090,906 (-)EnsemblGRCm39 Ensembl
GRCm38564,924,680 - 64,933,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl564,924,679 - 64,933,563 (-)EnsemblGRCm38mm10GRCm38
MGSCv37565,316,073 - 65,323,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,203,969 - 65,211,834 (-)NCBIMGSCv36mm8
Celera562,197,667 - 62,205,494 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.53NCBI
Tlr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,737,761 - 43,750,389 (+)NCBIGRCr8
mRatBN7.21443,384,127 - 43,396,765 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,384,932 - 43,397,125 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,753,982 - 43,756,546 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01445,053,936 - 45,056,500 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01443,534,102 - 43,536,666 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01445,062,662 - 45,065,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,062,662 - 45,081,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,871,931 - 44,874,283 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41446,114,913 - 46,124,820 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1442,538,240 - 42,540,804 (+)NCBICelera
Cytogenetic Map14p11NCBI
TLR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2338,984,530 - 39,034,230 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,177,045 - 39,226,757 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0433,119,485 - 33,133,541 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1438,973,623 - 38,981,413 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl438,979,006 - 38,981,366 (-)Ensemblpanpan1.1panPan2
TLR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1373,504,359 - 73,544,822 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl373,539,715 - 73,544,624 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha376,089,340 - 76,091,709 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0374,285,167 - 74,325,228 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl374,315,975 - 74,325,027 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1373,588,991 - 73,591,359 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,735,203 - 73,737,572 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0374,115,278 - 74,117,647 (+)NCBIUU_Cfam_GSD_1.0
Tlr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,707,097 - 39,715,850 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364826,582,584 - 6,584,971 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364826,582,430 - 6,591,128 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,147,624 - 30,155,466 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,147,600 - 30,155,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2831,627,675 - 31,660,825 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12711,482,307 - 11,490,847 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2711,488,294 - 11,490,654 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604757,897,098 - 57,911,767 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tlr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248407,287,781 - 7,290,162 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248407,287,772 - 7,349,282 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000025753   ⟹   ENSCLAP00000025494
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554438,447,956 - 8,450,382 (+)Ensembl
RefSeq Acc Id: XM_005391996   ⟹   XP_005392053
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554438,442,419 - 8,450,318 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005392053 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025494
  ENSCLAP00000025494.1
RefSeq Acc Id: XP_005392053   ⟸   XM_005391996
- UniProtKB: A0A8C2W6B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000025494   ⟸   ENSCLAT00000025753
Protein Domains
TIR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017579 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000025753 ENTREZGENE
  ENSCLAT00000025753.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  Toll-like_receptor UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
NCBI Gene Tlr1 ENTREZGENE
PANTHER PTHR24365 UniProtKB/TrEMBL
  PTHR24365:SF261 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PIRSF Toll-like_receptor UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF52200 UniProtKB/TrEMBL
UniProt A0A8C2W6B2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Tlr1  toll like receptor 1    toll-like receptor 1  Symbol and/or name change 5135510 APPROVED