Dclk3 (doublecortin like kinase 3) - Rat Genome Database

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Gene: Dclk3 (doublecortin like kinase 3) Chinchilla lanigera
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Symbol: Dclk3
Name: doublecortin like kinase 3
RGD ID: 9009279
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN negative regulation of protein localization to nucleus (ortholog); protein localization to nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: doublecortin-like kinase 3; serine/threonine-protein kinase DCLK3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554213,590,455 - 3,636,801 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554213,593,328 - 3,618,427 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Dclk3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554213,590,455 - 3,636,801 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554213,593,328 - 3,618,427 (-)NCBIChiLan1.0ChiLan1.0
DCLK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38336,712,421 - 36,764,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl336,712,421 - 36,764,553 (-)EnsemblGRCh38hg38GRCh38
GRCh37336,753,912 - 36,806,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36336,728,917 - 36,756,356 (-)NCBINCBI36Build 36hg18NCBI36
Celera336,696,656 - 36,724,088 (-)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef336,694,656 - 36,722,087 (-)NCBIHuRef
CHM1_1336,704,133 - 36,731,552 (-)NCBICHM1_1
T2T-CHM13v2.0336,713,774 - 36,765,897 (-)NCBIT2T-CHM13v2.0
Dclk3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399111,268,149 - 111,318,679 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9111,268,149 - 111,318,186 (+)EnsemblGRCm39 Ensembl
GRCm389111,439,081 - 111,489,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9111,439,081 - 111,489,118 (+)EnsemblGRCm38mm10GRCm38
MGSCv379111,341,585 - 111,392,115 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369111,283,929 - 111,333,929 (+)NCBIMGSCv36mm8
Celera9111,166,896 - 111,211,288 (+)NCBICelera
Cytogenetic Map9F3NCBI
cM Map961.33NCBI
Dclk3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88120,279,916 - 120,332,362 (+)NCBIGRCr8
mRatBN7.28111,401,544 - 111,453,999 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8111,401,358 - 111,453,999 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8117,017,621 - 117,069,994 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08115,216,862 - 115,269,245 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08113,059,687 - 113,112,073 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,691,567 - 119,744,484 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,691,388 - 119,744,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08119,040,830 - 119,093,605 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,830,472 - 115,883,560 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,849,754 - 115,902,190 (+)NCBI
Celera8110,683,369 - 110,735,326 (+)NCBICelera
Cytogenetic Map8q32NCBI
DCLK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2236,673,826 - 36,726,054 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1336,678,590 - 36,730,815 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0336,620,793 - 36,670,506 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1336,911,427 - 36,936,326 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl336,911,427 - 36,936,326 (-)Ensemblpanpan1.1panPan2
DCLK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,631,052 - 6,662,949 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha236,670,192 - 6,703,255 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,915,927 - 6,948,984 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1236,735,483 - 6,768,548 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0236,878,025 - 6,910,766 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,868,873 - 6,901,240 (-)NCBIUU_Cfam_GSD_1.0
Dclk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118193,161,622 - 193,203,351 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647326,299,761 - 26,341,884 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647326,300,195 - 26,320,953 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCLK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1322,040,510 - 22,095,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11322,040,518 - 22,095,477 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21323,860,743 - 23,989,814 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCLK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,641,036 - 2,690,573 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,666,575 - 2,693,611 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606311,378,325 - 11,429,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dclk3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478814,753,483 - 14,787,715 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478814,753,550 - 14,787,721 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000007797   ⟹   ENSCLAP00000007678
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554213,590,455 - 3,636,801 (-)Ensembl
RefSeq Acc Id: XM_013513810   ⟹   XP_013369264
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554213,593,328 - 3,618,427 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013369264 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007678
  ENSCLAP00000007678.1
RefSeq Acc Id: XP_013369264   ⟸   XM_013513810
- UniProtKB: A0A8C2UZ83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007678   ⟸   ENSCLAT00000007797
Protein Domains
Doublecortin   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005385 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007797 ENTREZGENE
  ENSCLAT00000007797.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.230 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Doublecortin_dom UniProtKB/TrEMBL
  Doublecortin_dom_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Dclk3 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE DCLK3 UniProtKB/TrEMBL
Pfam DCX UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  PS50309 UniProtKB/TrEMBL
SMART DCX UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
  SSF89837 UniProtKB/TrEMBL
UniProt A0A8C2UZ83 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Dclk3  doublecortin like kinase 3    doublecortin-like kinase 3  Symbol and/or name change 5135510 APPROVED