Snx25 (sorting nexin 25) - Rat Genome Database

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Gene: Snx25 (sorting nexin 25) Chinchilla lanigera
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Symbol: Snx25
Name: sorting nexin 25
RGD ID: 8953266
Description: ENCODES a protein that exhibits type I transforming growth factor beta receptor binding (ortholog); INVOLVED IN negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); receptor catabolic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); dilated cardiomyopathy (ortholog); genetic disease (ortholog); FOUND IN endosome (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sorting nexin-25
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540323,676,002 - 23,787,308 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540323,678,301 - 23,787,256 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Snx25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540323,676,002 - 23,787,308 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540323,678,301 - 23,787,256 (-)NCBIChiLan1.0ChiLan1.0
SNX25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384185,204,237 - 185,378,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4185,204,237 - 185,370,185 (+)EnsemblGRCh38hg38GRCh38
GRCh374186,125,391 - 186,285,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364186,368,278 - 186,522,114 (+)NCBINCBI36Build 36hg18NCBI36
Build 344186,506,432 - 186,660,267NCBI
Celera4183,458,214 - 183,611,271 (+)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4181,885,306 - 182,038,630 (+)NCBIHuRef
CHM1_14186,107,800 - 186,261,551 (+)NCBICHM1_1
T2T-CHM13v2.04188,547,948 - 188,721,939 (+)NCBIT2T-CHM13v2.0
Snx25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39846,486,298 - 46,605,535 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl846,486,298 - 46,605,196 (-)EnsemblGRCm39 Ensembl
GRCm38846,033,261 - 46,152,441 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl846,033,261 - 46,152,159 (-)EnsemblGRCm38mm10GRCm38
MGSCv37847,118,615 - 47,209,500 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36847,532,089 - 47,615,519 (-)NCBIMGSCv36mm8
Celera848,716,126 - 48,805,692 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.03NCBI
Snx25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81652,867,102 - 52,971,028 (+)NCBIGRCr8
mRatBN7.21646,134,552 - 46,238,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,125,804 - 46,238,440 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01649,328,958 - 49,432,415 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1649,350,884 - 49,432,118 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,051,539 - 49,159,381 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,415,658 - 49,518,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11649,415,438 - 49,518,714 (+)NCBI
Celera1644,133,781 - 44,236,984 (+)NCBICelera
Cytogenetic Map16q11NCBI
SNX25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23182,919,189 - 183,101,546 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14183,267,470 - 183,449,896 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04177,377,302 - 177,529,601 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,631,239 - 189,746,590 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,631,239 - 189,746,590 (+)Ensemblpanpan1.1panPan2
SNX25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,269,434 - 45,411,890 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,269,412 - 45,403,719 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1645,757,002 - 45,899,584 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01647,485,851 - 47,628,628 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1647,485,862 - 47,621,172 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11645,454,112 - 45,588,797 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,066,177 - 46,201,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,197,403 - 46,340,369 (-)NCBIUU_Cfam_GSD_1.0
Snx25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,020,358 - 34,127,227 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,979,441 - 4,087,162 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,982,755 - 4,093,143 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1546,266,762 - 46,388,324 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11546,306,967 - 46,388,404 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,105,358 - 53,186,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNX25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17131,171,833 - 131,320,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7131,207,046 - 131,313,261 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037111,432,323 - 111,584,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476916,058,827 - 16,220,716 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000018250   ⟹   ENSCLAP00000018072
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540323,676,002 - 23,787,308 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000018251   ⟹   ENSCLAP00000018073
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540323,678,818 - 23,772,793 (-)Ensembl
RefSeq Acc Id: XM_005373470   ⟹   XP_005373527
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540323,678,301 - 23,787,255 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512963   ⟹   XP_013368417
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540323,678,301 - 23,782,026 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512965   ⟹   XP_013368419
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540323,678,301 - 23,787,256 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373527 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368417 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368419 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018072
  ENSCLAP00000018072.1
  ENSCLAP00000018073
  ENSCLAP00000018073.1
RefSeq Acc Id: XP_005373527   ⟸   XM_005373470
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VTD2 (UniProtKB/TrEMBL),   A0A8C2VMZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368419   ⟸   XM_013512965
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VMZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368417   ⟸   XM_013512963
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VMZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018072   ⟸   ENSCLAT00000018250
RefSeq Acc Id: ENSCLAP00000018073   ⟸   ENSCLAT00000018251
Protein Domains
PX   PXA   RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012397 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018250 ENTREZGENE
  ENSCLAT00000018250.1 UniProtKB/TrEMBL
  ENSCLAT00000018251 ENTREZGENE
  ENSCLAT00000018251.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
InterPro Phox_assoc UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
  SNX25_PX UniProtKB/TrEMBL
  Sorting_nexin_C UniProtKB/TrEMBL
NCBI Gene Snx25 ENTREZGENE
PANTHER PTHR22775:SF29 UniProtKB/TrEMBL
  SORTING NEXIN UniProtKB/TrEMBL
Pfam Nexin_C UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
SMART PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A8C2VMZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VTD2 ENTREZGENE, UniProtKB/TrEMBL