Dock10 (dedicator of cytokinesis 10) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Dock10 (dedicator of cytokinesis 10) Chinchilla lanigera
Analyze
Symbol: Dock10
Name: dedicator of cytokinesis 10
RGD ID: 8949450
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN B cell homeostasis (ortholog); dendritic spine morphogenesis (ortholog); marginal zone B cell differentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dedicator of cytokinesis protein 10
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554539,264,666 - 9,424,570 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dock10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554539,264,666 - 9,424,570 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBIChiLan1.0ChiLan1.0
DOCK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,765,090 - 225,042,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,765,090 - 225,042,468 (-)EnsemblGRCh38hg38GRCh38
GRCh372225,629,807 - 225,907,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362225,338,051 - 225,615,574 (-)NCBINCBI36Build 36hg18NCBI36
Build 342225,455,312 - 225,524,418NCBI
Celera2219,395,607 - 219,675,879 (-)NCBICelera
Cytogenetic Map2q36.2NCBI
HuRef2217,481,808 - 217,758,286 (-)NCBIHuRef
CHM1_12225,636,434 - 225,913,936 (-)NCBICHM1_1
T2T-CHM13v2.02225,247,277 - 225,524,737 (-)NCBIT2T-CHM13v2.0
Dock10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39180,478,785 - 80,736,482 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl180,478,790 - 80,736,244 (-)EnsemblGRCm39 Ensembl
GRCm38180,501,068 - 80,758,765 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl180,501,073 - 80,758,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv37180,497,648 - 80,755,128 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36180,380,092 - 80,639,194 (-)NCBIMGSCv36mm8
MGSCv36181,370,369 - 81,462,919 (-)NCBIMGSCv36mm8
Celera180,532,070 - 80,781,493 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map141.41NCBI
Dock10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8989,291,936 - 89,549,871 (-)NCBIGRCr8
mRatBN7.2981,843,599 - 82,101,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl981,843,604 - 82,101,525 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0986,424,638 - 86,571,854 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0986,312,470 - 86,423,054 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl986,312,501 - 86,571,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0986,061,318 - 86,224,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4979,839,310 - 80,100,968 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera979,317,922 - 79,576,133 (-)NCBICelera
Cytogenetic Map9q34NCBI
DOCK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213127,380,252 - 127,658,039 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B127,395,221 - 127,672,642 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B112,006,479 - 112,283,939 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B230,577,925 - 230,794,767 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B230,578,452 - 230,854,877 (-)Ensemblpanpan1.1panPan2
DOCK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12537,962,666 - 38,161,396 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2537,963,297 - 38,161,305 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2538,575,692 - 38,835,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02538,205,067 - 38,465,062 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2538,205,069 - 38,465,132 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12538,145,247 - 38,404,941 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02537,980,034 - 38,244,304 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02538,161,004 - 38,421,331 (-)NCBIUU_Cfam_GSD_1.0
Dock10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303179,931,913 - 180,119,337 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365696,274,714 - 6,462,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365696,274,747 - 6,462,265 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15126,435,579 - 126,711,531 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115126,435,577 - 126,711,755 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215139,929,518 - 140,211,279 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110110,718,256 - 111,001,599 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10110,718,258 - 110,904,005 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604088,415,711 - 88,691,896 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dock10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624823448,189 - 624,740 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624823417,567 - 625,324 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000011594   ⟹   ENSCLAP00000011457
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554539,264,666 - 9,420,326 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000011595   ⟹   ENSCLAP00000011458
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554539,279,785 - 9,424,570 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000011596   ⟹   ENSCLAP00000011459
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554539,331,036 - 9,423,877 (+)Ensembl
RefSeq Acc Id: XM_005395477   ⟹   XP_005395534
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005395478   ⟹   XP_005395535
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005395479   ⟹   XP_005395536
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,264,526 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519949   ⟹   XP_013375403
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519950   ⟹   XP_013375404
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519951   ⟹   XP_013375405
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,264,526 - 9,424,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519952   ⟹   XP_013375406
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554539,264,526 - 9,424,570 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005395534   ⟸   XM_005395477
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005395535   ⟸   XM_005395478
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V7J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005395536   ⟸   XM_005395479
- Peptide Label: isoform X7
- UniProtKB: A0A8C2V7J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375404   ⟸   XM_013519950
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V7J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375403   ⟸   XM_013519949
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V7J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375405   ⟸   XM_013519951
- Peptide Label: isoform X5
- UniProtKB: A0A8C2V7J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375406   ⟸   XM_013519952
- Peptide Label: isoform X6
- UniProtKB: A0A8C2V7J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000011458   ⟸   ENSCLAT00000011595
RefSeq Acc Id: ENSCLAP00000011457   ⟸   ENSCLAT00000011594
RefSeq Acc Id: ENSCLAP00000011459   ⟸   ENSCLAT00000011596
Protein Domains
C2 DOCK-type   DOCKER   PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007903 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011594.1 UniProtKB/TrEMBL
  ENSCLAT00000011595 ENTREZGENE
  ENSCLAT00000011595.1 UniProtKB/TrEMBL
  ENSCLAT00000011596 ENTREZGENE
  ENSCLAT00000011596.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.740 UniProtKB/TrEMBL
  1.25.40.410 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  C2_Dock-D UniProtKB/TrEMBL
  C2_DOCK-type_domain UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK_C/D_N UniProtKB/TrEMBL
  DOCK_C_lobe_A UniProtKB/TrEMBL
  DOCK_C_lobe_C UniProtKB/TrEMBL
  DOCKER_dom UniProtKB/TrEMBL
  DOCKER_Lobe_A UniProtKB/TrEMBL
  DOCKER_Lobe_B UniProtKB/TrEMBL
  DOCKER_Lobe_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Dock10 ENTREZGENE
PANTHER DEDICATOR OF CYTOKINESIS PROTEIN 10 UniProtKB/TrEMBL
  PTHR23317 UniProtKB/TrEMBL
Pfam DHR-2 UniProtKB/TrEMBL
  DHR-2_Lobe_B UniProtKB/TrEMBL
  DHR-2_Lobe_C UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DUF3398 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PROSITE C2_DOCK UniProtKB/TrEMBL
  DOCKER UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A8C2V7J0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V7J1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V7T6_CHILA UniProtKB/TrEMBL