Dock10 (dedicator of cytokinesis 10) - Rat Genome Database

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Gene: Dock10 (dedicator of cytokinesis 10) Rattus norvegicus
Analyze
Symbol: Dock10
Name: dedicator of cytokinesis 10
RGD ID: 1561963
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including B cell homeostasis; dendritic spine morphogenesis; and marginal zone B cell differentiation. Predicted to be located in cytosol; dendritic spine; and nucleoplasm. Predicted to be active in glutamatergic synapse and postsynapse. Orthologous to human DOCK10 (dedicator of cytokinesis 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dedicator of cytokinesis protein 10; LOC301556; RGD1561963; similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8989,291,936 - 89,549,871 (-)NCBIGRCr8
mRatBN7.2981,843,599 - 82,101,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl981,843,604 - 82,101,525 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0986,424,638 - 86,571,854 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0986,312,470 - 86,423,054 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl986,312,501 - 86,571,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0986,061,318 - 86,224,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4979,839,310 - 80,100,968 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera979,317,922 - 79,576,133 (-)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
maneb  (ISO)
mercury atom  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
miconazole  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tacrolimus hydrate  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA,ISO)
dendritic spine  (ISO)
glutamatergic synapse  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)
postsynapse  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15710388   PMID:18499258   PMID:18835169   PMID:19946888   PMID:20458337   PMID:25729399   PMID:25851601   PMID:27502165  


Genomics

Comparative Map Data
Dock10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8989,291,936 - 89,549,871 (-)NCBIGRCr8
mRatBN7.2981,843,599 - 82,101,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl981,843,604 - 82,101,525 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0986,424,638 - 86,571,854 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0986,312,470 - 86,423,054 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl986,312,501 - 86,571,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0986,061,318 - 86,224,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4979,839,310 - 80,100,968 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera979,317,922 - 79,576,133 (-)NCBICelera
Cytogenetic Map9q34NCBI
DOCK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,765,090 - 225,042,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,765,090 - 225,042,468 (-)EnsemblGRCh38hg38GRCh38
GRCh372225,629,807 - 225,907,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362225,338,051 - 225,615,574 (-)NCBINCBI36Build 36hg18NCBI36
Build 342225,455,312 - 225,524,418NCBI
Celera2219,395,607 - 219,675,879 (-)NCBICelera
Cytogenetic Map2q36.2NCBI
HuRef2217,481,808 - 217,758,286 (-)NCBIHuRef
CHM1_12225,636,434 - 225,913,936 (-)NCBICHM1_1
T2T-CHM13v2.02225,247,277 - 225,524,737 (-)NCBIT2T-CHM13v2.0
Dock10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39180,478,785 - 80,736,482 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl180,478,790 - 80,736,244 (-)EnsemblGRCm39 Ensembl
GRCm38180,501,068 - 80,758,765 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl180,501,073 - 80,758,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv37180,497,648 - 80,755,128 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36180,380,092 - 80,639,194 (-)NCBIMGSCv36mm8
MGSCv36181,370,369 - 81,462,919 (-)NCBIMGSCv36mm8
Celera180,532,070 - 80,781,493 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map141.41NCBI
Dock10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554539,264,666 - 9,424,570 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554539,229,535 - 9,424,570 (+)NCBIChiLan1.0ChiLan1.0
DOCK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213127,380,252 - 127,658,039 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B127,395,221 - 127,672,642 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B112,006,479 - 112,283,939 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B230,577,925 - 230,794,767 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B230,578,452 - 230,854,877 (-)Ensemblpanpan1.1panPan2
DOCK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12537,962,666 - 38,161,396 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2537,963,297 - 38,161,305 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2538,575,692 - 38,835,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02538,205,067 - 38,465,062 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2538,205,069 - 38,465,132 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12538,145,247 - 38,404,941 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02537,980,034 - 38,244,304 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02538,161,004 - 38,421,331 (-)NCBIUU_Cfam_GSD_1.0
Dock10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303179,931,913 - 180,119,337 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365696,274,714 - 6,462,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365696,274,747 - 6,462,265 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15126,435,579 - 126,711,531 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115126,435,577 - 126,711,755 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215139,929,518 - 140,211,279 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110110,718,256 - 111,001,599 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10110,718,258 - 110,904,005 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604088,415,711 - 88,691,896 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dock10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624823448,189 - 624,740 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624823417,567 - 625,324 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dock10
1830 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat

Markers in Region
BE102977  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2981,905,896 - 81,906,054 (+)MAPPERmRatBN7.2
Rnor_6.0986,374,923 - 86,375,080NCBIRnor6.0
Rnor_5.0986,123,769 - 86,123,926UniSTSRnor5.0
RGSC_v3.4979,903,019 - 79,903,176UniSTSRGSC3.4
Celera979,380,168 - 79,380,325UniSTS
RH 3.4 Map9714.8UniSTS
Cytogenetic Map9q34UniSTS
RH140602  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2981,844,045 - 81,844,262 (+)MAPPERmRatBN7.2
Rnor_6.0986,312,914 - 86,313,130NCBIRnor6.0
Rnor_5.0986,061,760 - 86,061,976UniSTSRnor5.0
RGSC_v3.4979,839,752 - 79,839,968UniSTSRGSC3.4
Celera979,318,366 - 79,318,582UniSTS
RH 3.4 Map9716.9UniSTS
Cytogenetic Map9q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 10 19 1 1 32 2 6 11 1
Low 1 37 47 41 41 7 9 40 33 32 7
Below cutoff 6 1 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003754541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006226900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000077652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl986,313,108 - 86,475,662 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,847,649 - 82,006,048 (-)Ensembl
Rnor_6.0 Ensembl986,316,519 - 86,475,662 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,843,604 - 82,006,608 (-)Ensembl
Rnor_6.0 Ensembl986,316,695 - 86,459,852 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,843,604 - 82,101,525 (-)Ensembl
Rnor_6.0 Ensembl986,313,108 - 86,571,765 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,843,604 - 82,101,525 (-)Ensembl
Rnor_6.0 Ensembl986,312,501 - 86,419,044 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl986,315,023 - 86,459,852 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl986,396,334 - 86,516,451 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl986,379,398 - 86,571,870 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl981,843,604 - 82,046,557 (-)Ensembl
Rnor_6.0 Ensembl986,312,952 - 86,475,779 (-)Ensembl
RefSeq Acc Id: NM_001419911   ⟹   NP_001406840
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,454,498 (-)NCBI
mRatBN7.2981,843,604 - 82,006,168 (-)NCBI
RefSeq Acc Id: XM_008767311   ⟹   XP_008765533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,495,253 (-)NCBI
mRatBN7.2981,845,710 - 82,046,849 (-)NCBI
Rnor_6.0986,313,527 - 86,423,054 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767315   ⟹   XP_008765537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,495,253 (-)NCBI
mRatBN7.2981,843,599 - 82,046,532 (-)NCBI
Rnor_6.0986,312,470 - 86,423,054 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596832   ⟹   XP_017452321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,496,643 (-)NCBI
mRatBN7.2981,845,710 - 82,046,852 (-)NCBI
Rnor_6.0986,313,527 - 86,423,054 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039084666   ⟹   XP_038940594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,455,408 (-)NCBI
mRatBN7.2981,845,710 - 82,007,131 (-)NCBI
RefSeq Acc Id: XM_039084669   ⟹   XP_038940597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,549,871 (-)NCBI
mRatBN7.2981,843,599 - 82,101,447 (-)NCBI
RefSeq Acc Id: XM_039084671   ⟹   XP_038940599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,318,099 - 89,496,654 (-)NCBI
mRatBN7.2981,869,768 - 82,048,345 (-)NCBI
RefSeq Acc Id: XM_063267000   ⟹   XP_063123070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,495,253 (-)NCBI
RefSeq Acc Id: XM_063267001   ⟹   XP_063123071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,496,642 (-)NCBI
RefSeq Acc Id: XM_063267002   ⟹   XP_063123072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,549,871 (-)NCBI
RefSeq Acc Id: XM_063267003   ⟹   XP_063123073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,549,871 (-)NCBI
RefSeq Acc Id: XM_063267004   ⟹   XP_063123074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,495,253 (-)NCBI
RefSeq Acc Id: XM_063267005   ⟹   XP_063123075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,455,409 (-)NCBI
RefSeq Acc Id: XM_063267006   ⟹   XP_063123076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,495,253 (-)NCBI
RefSeq Acc Id: XM_063267007   ⟹   XP_063123077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,455,408 (-)NCBI
RefSeq Acc Id: XM_063267008   ⟹   XP_063123078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,455,408 (-)NCBI
RefSeq Acc Id: XM_063267009   ⟹   XP_063123079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,294,071 - 89,455,413 (-)NCBI
RefSeq Acc Id: XM_063267010   ⟹   XP_063123080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8989,291,936 - 89,455,398 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008765537   ⟸   XM_008767315
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ADN8 (UniProtKB/TrEMBL),   A6JW89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765533   ⟸   XM_008767311
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452321   ⟸   XM_017596832
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZNM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038940597   ⟸   XM_039084669
- Peptide Label: isoform X15
- UniProtKB: A0A8I6G204 (UniProtKB/TrEMBL),   A6JW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940594   ⟸   XM_039084666
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZZI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038940599   ⟸   XM_039084671
- Peptide Label: isoform X17
RefSeq Acc Id: NP_001406840   ⟸   NM_001419911
- UniProtKB: A0A8I6AIC2 (UniProtKB/TrEMBL),   A0A8I5ZZI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123076   ⟸   XM_063267006
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063123074   ⟸   XM_063267004
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063123080   ⟸   XM_063267010
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063123073   ⟸   XM_063267003
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063123072   ⟸   XM_063267002
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123071   ⟸   XM_063267001
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063123070   ⟸   XM_063267000
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063123079   ⟸   XM_063267009
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063123075   ⟸   XM_063267005
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063123078   ⟸   XM_063267008
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063123077   ⟸   XM_063267007
- Peptide Label: isoform X11
Protein Domains
C2 DOCK-type   DOCKER   PH

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561963 AgrOrtholog
BioCyc Gene G2FUF-27002 BioCyc
Ensembl Genes ENSRNOG00000053200 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081067.2 UniProtKB/TrEMBL
  ENSRNOT00000083988 ENTREZGENE
  ENSRNOT00000083988.2 UniProtKB/TrEMBL
  ENSRNOT00000088747.2 UniProtKB/TrEMBL
  ENSRNOT00000091881.2 UniProtKB/TrEMBL
  ENSRNOT00000093635.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.740 UniProtKB/TrEMBL
  1.25.40.410 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_Dock-D UniProtKB/TrEMBL
  C2_DOCK-type_domain UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK_C/D_N UniProtKB/TrEMBL
  DOCK_C_lobe_A UniProtKB/TrEMBL
  DOCK_C_lobe_C UniProtKB/TrEMBL
  DOCKER_dom UniProtKB/TrEMBL
  DOCKER_Lobe_A UniProtKB/TrEMBL
  DOCKER_Lobe_B UniProtKB/TrEMBL
  DOCKER_Lobe_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene 301556 ENTREZGENE
PANTHER DEDICATOR OF CYTOKINESIS PROTEIN 10 UniProtKB/TrEMBL
  PTHR23317 UniProtKB/TrEMBL
Pfam DHR-2 UniProtKB/TrEMBL
  DHR-2_Lobe_B UniProtKB/TrEMBL
  DHR-2_Lobe_C UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DUF3398 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Dock10 PhenoGen
PROSITE C2_DOCK UniProtKB/TrEMBL
  DOCKER UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053200 RatGTEx
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZNM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G204 ENTREZGENE, UniProtKB/TrEMBL
  A6JW89 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-25 Dock10  dedicator of cytokinesis 10  RGD1561963  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561963  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3)   RGD1561963_predicted  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561963_predicted  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3) (predicted)  LOC301556  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC301556  similar to Dedicator of cytokinesis protein 10 (Protein zizimin 3)      Symbol and Name status set to provisional 70820 PROVISIONAL