Ppp1r9b (protein phosphatase 1 regulatory subunit 9B) - Rat Genome Database

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Gene: Ppp1r9b (protein phosphatase 1 regulatory subunit 9B) Chinchilla lanigera
Analyze
Symbol: Ppp1r9b
Name: protein phosphatase 1 regulatory subunit 9B
RGD ID: 8890650
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurabin-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,516,548 - 11,530,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,516,548 - 11,530,263 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament depolymerization  (ISO)
actin filament organization  (ISO)
calcium-mediated signaling  (ISO)
cell migration  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to morphine  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to peptide  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (ISO)
dendrite development  (ISO)
developmental process involved in reproduction  (ISO)
filopodium assembly  (ISO)
hippocampus development  (ISO)
learning  (ISO)
male mating behavior  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of phosphoprotein phosphatase activity  (ISO)
positive regulation of protein localization  (ISO)
positive regulation of protein localization to actin cortical patch  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
protein localization to actin cytoskeleton  (ISO)
protein localization to cell periphery  (ISO)
regulation of opioid receptor signaling pathway  (ISO)
regulation of postsynapse assembly  (ISO)
regulation of protein phosphorylation  (ISO)
reproductive system development  (ISO)
response to amino acid  (ISO)
response to amphetamine  (ISO)
response to estradiol  (ISO)
response to immobilization stress  (ISO)
response to kainic acid  (ISO)
response to L-phenylalanine derivative  (ISO)
response to nicotine  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to prostaglandin E  (ISO)
response to steroid hormone  (ISO)
response to xenobiotic stimulus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ppp1r9b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,516,548 - 11,530,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,516,548 - 11,530,263 (+)NCBIChiLan1.0ChiLan1.0
PPP1R9B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381750,133,737 - 50,150,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1750,133,737 - 50,150,677 (-)EnsemblGRCh38hg38GRCh38
GRCh371748,211,101 - 48,228,038 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,566,100 - 45,582,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 341745,567,694 - 45,582,873NCBI
Celera1744,671,218 - 44,687,998 (-)NCBICelera
Cytogenetic Map17q21.33NCBI
HuRef1743,578,978 - 43,595,756 (-)NCBIHuRef
CHM1_11748,275,419 - 48,292,198 (-)NCBICHM1_1
T2T-CHM13v2.01751,000,814 - 51,017,737 (-)NCBIT2T-CHM13v2.0
Ppp1r9b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,882,038 - 94,897,724 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,881,861 - 94,897,725 (+)EnsemblGRCm39 Ensembl
GRCm381194,991,212 - 95,006,898 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,991,035 - 95,006,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,852,526 - 94,868,212 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,807,302 - 94,822,974 (+)NCBIMGSCv36mm8
Celera11104,604,585 - 104,620,251 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
Ppp1r9b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81080,434,888 - 80,450,919 (+)NCBIGRCr8
mRatBN7.21079,938,055 - 79,954,085 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1079,938,066 - 79,954,083 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1084,887,200 - 84,903,206 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01084,385,269 - 84,401,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01079,778,362 - 79,794,325 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,800,704 - 82,816,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,800,704 - 82,816,731 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,616,223 - 82,632,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,674,797 - 83,690,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11083,689,166 - 83,705,009 (+)NCBI
Celera1078,712,214 - 78,727,757 (+)NCBICelera
Cytogenetic Map10q26NCBI
PPP1R9B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,322,412 - 66,339,660 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11771,128,896 - 71,146,153 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,224,007 - 44,240,906 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11749,098,089 - 49,129,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,098,089 - 49,126,932 (-)Ensemblpanpan1.1panPan2
PPP1R9B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,135,982 - 26,152,303 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,529,124 - 25,544,951 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0926,930,469 - 26,946,307 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl926,930,469 - 26,946,307 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1925,698,261 - 25,714,094 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0925,956,940 - 25,972,777 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0926,086,858 - 26,102,695 (-)NCBIUU_Cfam_GSD_1.0
Ppp1r9b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,560,948 - 25,577,086 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649011,497,389 - 11,514,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R9B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,319,124 - 26,336,562 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,319,123 - 26,337,089 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,358,245 - 26,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R9B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11643,188,400 - 43,205,621 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1643,188,022 - 43,205,680 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607713,904,402 - 13,921,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r9b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247956,124,159 - 6,137,955 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247956,124,273 - 6,137,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018077   ⟹   ENSCLAP00000017899
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545111,516,548 - 11,530,830 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018078   ⟹   ENSCLAP00000017900
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545111,516,644 - 11,528,706 (+)Ensembl
RefSeq Acc Id: XM_005394179   ⟹   XP_005394236
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545111,516,548 - 11,530,263 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394236 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017899
  ENSCLAP00000017899.1
  ENSCLAP00000017900.1
Reference Protein Sequences
RefSeq Acc Id: XP_005394236   ⟸   XM_005394179
- UniProtKB: A0A8C2VV08 (UniProtKB/TrEMBL),   A0A8C2VPX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017900   ⟸   ENSCLAT00000018078
RefSeq Acc Id: ENSCLAP00000017899   ⟸   ENSCLAT00000018077
Protein Domains
PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012282 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018077 ENTREZGENE
  ENSCLAT00000018077.1 UniProtKB/TrEMBL
  ENSCLAT00000018078.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro Neurabin-1/2_PDZ UniProtKB/TrEMBL
  Neurabin-like UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene Ppp1r9b ENTREZGENE
PANTHER PTHR16154 UniProtKB/TrEMBL
  PTHR16154:SF24 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PDZ_5 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A8C2VPX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VV08 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Ppp1r9b  protein phosphatase 1 regulatory subunit 9B    protein phosphatase 1, regulatory subunit 9B  Symbol and/or name change 5135510 APPROVED