Nwd1 (NACHT and WD repeat domain containing 1) - Rat Genome Database

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Gene: Nwd1 (NACHT and WD repeat domain containing 1) Chinchilla lanigera
Analyze
Symbol: Nwd1
Name: NACHT and WD repeat domain containing 1
RGD ID: 8885164
Description: INVOLVED IN positive regulation of gene expression (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NACHT domain- and WD repeat-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555241,084,750 - 1,121,689 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555241,083,237 - 1,122,615 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleolus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nwd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555241,084,750 - 1,121,689 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555241,083,237 - 1,122,615 (-)NCBIChiLan1.0ChiLan1.0
NWD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,719,847 - 16,817,963 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1916,719,847 - 16,817,963 (+)EnsemblGRCh38hg38GRCh38
GRCh371916,830,658 - 16,928,774 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,691,787 - 16,789,764 (+)NCBINCBI36Build 36hg18NCBI36
Celera1916,732,646 - 16,830,313 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1916,399,721 - 16,497,684 (+)NCBIHuRef
CHM1_11916,830,805 - 16,928,529 (+)NCBICHM1_1
T2T-CHM13v2.01916,854,654 - 16,952,783 (+)NCBIT2T-CHM13v2.0
Nwd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39873,372,865 - 73,443,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl873,373,339 - 73,444,504 (+)EnsemblGRCm39 Ensembl
GRCm38872,646,225 - 72,716,880 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,646,711 - 72,717,876 (+)EnsemblGRCm38mm10GRCm38
MGSCv37875,170,610 - 75,238,645 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36875,540,415 - 75,604,144 (+)NCBIMGSCv36mm8
Celera876,962,656 - 77,030,120 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map835.08NCBI
Nwd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81617,204,731 - 17,278,184 (-)NCBIGRCr8
mRatBN7.21617,166,479 - 17,242,055 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,170,659 - 17,252,705 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01618,875,768 - 18,944,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1618,877,257 - 18,937,562 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,740,763 - 18,803,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1617,396,593 - 17,464,531 (-)NCBICelera
Cytogenetic Map16p14NCBI
NWD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22021,591,857 - 21,688,508 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11920,598,431 - 20,695,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01916,209,324 - 16,305,897 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11917,189,728 - 17,283,045 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1917,202,805 - 17,281,335 (+)Ensemblpanpan1.1panPan2
NWD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,792,745 - 45,854,889 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,794,306 - 45,852,100 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,706,235 - 45,772,311 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02046,279,282 - 46,345,502 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2046,279,297 - 46,345,510 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12045,514,886 - 45,581,005 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,925,619 - 45,991,612 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,201,195 - 46,266,989 (-)NCBIUU_Cfam_GSD_1.0
Nwd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118204,330,959 - 204,399,516 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365963,884,269 - 3,942,406 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365963,882,259 - 3,948,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NWD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl260,800,438 - 60,906,046 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1260,800,064 - 60,906,536 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2260,406,949 - 60,494,692 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NWD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,255,116 - 15,318,589 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl615,221,120 - 15,318,470 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660744,119,126 - 4,220,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nwd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624908799,402 - 828,353 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624908797,891 - 830,857 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000010949   ⟹   ENSCLAP00000010816
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555241,084,750 - 1,121,689 (-)Ensembl
RefSeq Acc Id: XM_005409503   ⟹   XP_005409560
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555241,083,237 - 1,122,615 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409560 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010816
  ENSCLAP00000010816.1
Reference Protein Sequences
RefSeq Acc Id: XP_005409560   ⟸   XM_005409503
- UniProtKB: A0A8C2V7E1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000010816   ⟸   ENSCLAT00000010949


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007464 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010949 ENTREZGENE
  ENSCLAT00000010949.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro NWD1 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Quinoprotein_ADH-like_supfam UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Nwd1 ENTREZGENE
PANTHER NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR45013 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF50998 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2V7E1 ENTREZGENE, UniProtKB/TrEMBL