Nek1 (NIMA related kinase 1) - Rat Genome Database

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Gene: Nek1 (NIMA related kinase 1) Chinchilla lanigera
Analyze
Symbol: Nek1
Name: NIMA related kinase 1
RGD ID: 8855100
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); kinase activity (ortholog); protein kinase activity (ortholog); INVOLVED IN cilium assembly (ortholog); DNA damage response (ortholog); kidney development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 24 (ortholog); asphyxiating thoracic dystrophy (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NIMA-related kinase 1; serine/threonine-protein kinase Nek1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540336,720,162 - 36,881,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540336,710,248 - 36,878,901 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nek1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540336,720,162 - 36,881,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540336,710,248 - 36,878,901 (+)NCBIChiLan1.0ChiLan1.0
NEK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384169,392,809 - 169,612,583 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4169,369,704 - 169,612,632 (-)EnsemblGRCh38hg38GRCh38
GRCh374170,313,960 - 170,533,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364170,551,004 - 170,770,189 (-)NCBINCBI36Build 36hg18NCBI36
Build 344170,689,158 - 170,908,344NCBI
Celera4167,647,120 - 167,866,584 (-)NCBICelera
Cytogenetic Map4q33NCBI
HuRef4166,069,151 - 166,288,552 (-)NCBIHuRef
CHM1_14170,290,871 - 170,510,372 (-)NCBICHM1_1
T2T-CHM13v2.04172,752,512 - 172,972,332 (-)NCBIT2T-CHM13v2.0
Nek1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39861,446,184 - 61,584,383 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl861,446,229 - 61,584,380 (+)EnsemblGRCm39 Ensembl
GRCm38860,993,157 - 61,131,349 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl860,993,195 - 61,131,346 (+)EnsemblGRCm38mm10GRCm38
MGSCv37863,472,017 - 63,609,031 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36863,885,335 - 64,023,496 (+)NCBIMGSCv36mm8
Celera863,560,390 - 63,696,381 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map830.91NCBI
Nek1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81634,009,092 - 34,137,418 (-)NCBIGRCr8
mRatBN7.21628,998,229 - 29,125,426 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,998,231 - 29,117,723 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1632,593,117 - 32,712,602 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01636,026,844 - 36,146,328 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01632,228,326 - 32,347,844 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01632,321,010 - 32,439,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1632,321,010 - 32,439,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01632,155,914 - 32,274,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01631,025,718 - 31,032,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41632,317,987 - 32,438,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11632,320,904 - 32,431,386 (-)NCBI
Celera1628,993,115 - 29,112,552 (-)NCBICelera
Cytogenetic Map16p12NCBI
NEK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23167,174,897 - 167,388,951 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14167,530,541 - 167,744,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04161,618,181 - 161,830,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14173,690,074 - 173,902,100 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4173,690,074 - 173,902,100 (-)Ensemblpanpan1.1panPan2
NEK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12520,297,190 - 20,528,537 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2520,299,079 - 20,518,483 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2520,934,647 - 21,153,217 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02520,475,506 - 20,704,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2520,475,503 - 20,694,127 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12520,318,819 - 20,578,371 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02520,295,186 - 20,524,672 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02520,394,714 - 20,624,101 (-)NCBIUU_Cfam_GSD_1.0
Nek1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494321,094,565 - 21,252,579 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365161,508,811 - 1,666,869 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365161,508,800 - 1,666,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,144,659 - 20,332,245 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,144,631 - 20,332,248 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,439,141 - 21,626,347 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17115,621,917 - 115,819,349 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7115,621,916 - 115,819,291 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603795,560,952 - 95,765,438 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nek1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624769945,644 - 1,147,246 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624769945,788 - 1,146,921 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000020625   ⟹   ENSCLAP00000020427
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540336,720,162 - 36,881,891 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020626   ⟹   ENSCLAP00000020428
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540336,720,162 - 36,881,891 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020627   ⟹   ENSCLAP00000020429
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540336,720,162 - 36,881,891 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020628   ⟹   ENSCLAP00000020430
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540336,728,762 - 36,877,697 (+)Ensembl
RefSeq Acc Id: XM_013513368   ⟹   XP_013368822
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540336,710,248 - 36,878,901 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013368822 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020427
  ENSCLAP00000020427.1
  ENSCLAP00000020428.1
  ENSCLAP00000020429.1
  ENSCLAP00000020430.1
Reference Protein Sequences
RefSeq Acc Id: XP_013368822   ⟸   XM_013513368
- UniProtKB: A0A8C2VTI4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000020427   ⟸   ENSCLAT00000020625
RefSeq Acc Id: ENSCLAP00000020429   ⟸   ENSCLAT00000020627
RefSeq Acc Id: ENSCLAP00000020428   ⟸   ENSCLAT00000020626
RefSeq Acc Id: ENSCLAP00000020430   ⟸   ENSCLAT00000020628
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013999 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020625 ENTREZGENE
  ENSCLAT00000020625.1 UniProtKB/TrEMBL
  ENSCLAT00000020626.1 UniProtKB/TrEMBL
  ENSCLAT00000020627.1 UniProtKB/TrEMBL
  ENSCLAT00000020628.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Nek1 ENTREZGENE
PANTHER CAMK FAMILY PROTEIN KINASE UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE NEK1 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VTI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VTV4_CHILA UniProtKB/TrEMBL
  A0A8C2YSN9_CHILA UniProtKB/TrEMBL
  A0A8C2YSP2_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Nek1  NIMA related kinase 1    NIMA-related kinase 1  Symbol and/or name change 5135510 APPROVED