Dmpk (DM1 protein kinase) - Rat Genome Database

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Gene: Dmpk (DM1 protein kinase) Chinchilla lanigera
Analyze
Symbol: Dmpk
Name: DM1 protein kinase
RGD ID: 8834922
Description: ENCODES a protein that exhibits ATP binding (ortholog); myosin phosphatase regulator activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); muscle cell apoptotic process (ortholog); nuclear envelope organization (ortholog); ASSOCIATED WITH catecholaminergic polymorphic ventricular tachycardia 1 (ortholog); genetic disease (ortholog); Myotonia (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrial outer membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dystrophia myotonica protein kinase; dystrophia myotonica-protein kinase; myotonin-protein kinase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574226,292 - 237,526 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574225,615 - 237,526 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dmpk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574226,292 - 237,526 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574225,615 - 237,526 (-)NCBIChiLan1.0ChiLan1.0
DMPK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,769,709 - 45,782,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,769,709 - 45,782,552 (-)EnsemblGRCh38hg38GRCh38
GRCh371946,272,967 - 46,285,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,964,815 - 50,977,655 (-)NCBINCBI36Build 36hg18NCBI36
Build 341950,964,815 - 50,977,576NCBI
Celera1943,079,095 - 43,090,866 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,701,722 - 42,714,534 (-)NCBIHuRef
CHM1_11946,276,489 - 46,288,326 (-)NCBICHM1_1
T2T-CHM13v2.01948,597,244 - 48,609,980 (-)NCBIT2T-CHM13v2.0
Dmpk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,817,571 - 18,827,746 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,817,774 - 18,827,746 (+)EnsemblGRCm39 Ensembl
GRCm38719,083,646 - 19,093,821 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,083,849 - 19,093,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,669,198 - 19,679,170 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,242,517 - 18,251,624 (+)NCBIMGSCv36mm8
Celera716,495,229 - 16,505,182 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Dmpk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,858,294 - 87,868,624 (+)NCBIGRCr8
mRatBN7.2178,730,255 - 78,740,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,730,275 - 78,740,593 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,119,202 - 84,129,502 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,676,889 - 92,687,183 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,874,300 - 85,884,600 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,988,096 - 79,999,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,989,019 - 79,999,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,257,000 - 81,267,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,449,324 - 78,450,578 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,518,239 - 78,529,227 (+)NCBI
Celera173,194,993 - 73,206,254 (+)NCBICelera
Cytogenetic Map1q21NCBI
DMPK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,935,294 - 51,948,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,806,747 - 53,819,563 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,779,173 - 42,791,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,316,099 - 51,329,421 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,316,099 - 51,329,355 (-)Ensemblpanpan1.1panPan2
DMPK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,824,103 - 109,834,986 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,824,597 - 109,834,976 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,309,270 - 109,320,016 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,357,335 - 110,368,093 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,357,272 - 110,368,093 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,032,956 - 110,043,712 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,667,626 - 109,678,376 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,536,417 - 110,547,165 (+)NCBIUU_Cfam_GSD_1.0
Dmpk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,777,894 - 17,788,794 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,124,238 - 2,134,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,125,237 - 2,135,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DMPK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,100,259 - 52,110,478 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,100,259 - 52,110,822 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DMPK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,219,625 - 39,232,203 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,220,355 - 39,232,015 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,852,196 - 18,865,776 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dmpk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,419,689 - 7,429,084 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,419,529 - 7,429,744 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001020   ⟹   ENSCLAP00000000982
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955574226,292 - 237,526 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001021   ⟹   ENSCLAP00000000983
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955574227,019 - 237,526 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001022   ⟹   ENSCLAP00000000984
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955574232,771 - 236,330 (-)Ensembl
RefSeq Acc Id: XM_005413811   ⟹   XP_005413868
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005413812   ⟹   XP_005413869
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574225,615 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005413813   ⟹   XP_005413870
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509518   ⟹   XP_013364972
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509519   ⟹   XP_013364973
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509520   ⟹   XP_013364974
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509521   ⟹   XP_013364975
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,250 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509522   ⟹   XP_013364976
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,271 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509523   ⟹   XP_013364977
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574227,019 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509524   ⟹   XP_013364978
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,271 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509525   ⟹   XP_013364979
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574227,019 - 237,526 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509526   ⟹   XP_013364980
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955574226,292 - 237,526 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005413869   ⟸   XM_005413812
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005413870   ⟸   XM_005413813
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005413868   ⟸   XM_005413811
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YIF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364975   ⟸   XM_013509521
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_013364978   ⟸   XM_013509524
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_013364976   ⟸   XM_013509522
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_013364973   ⟸   XM_013509519
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013364974   ⟸   XM_013509520
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013364972   ⟸   XM_013509518
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013364980   ⟸   XM_013509526
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_013364979   ⟸   XM_013509525
- Peptide Label: isoform X11
- UniProtKB: A0A8C2UJA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364977   ⟸   XM_013509523
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: ENSCLAP00000000982   ⟸   ENSCLAT00000001020
RefSeq Acc Id: ENSCLAP00000000984   ⟸   ENSCLAT00000001022
RefSeq Acc Id: ENSCLAP00000000983   ⟸   ENSCLAT00000001021
Protein Domains
AGC-kinase C-terminal   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000761 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001020 ENTREZGENE
  ENSCLAT00000001020.1 UniProtKB/TrEMBL
  ENSCLAT00000001021 ENTREZGENE
  ENSCLAT00000001021.1 UniProtKB/TrEMBL
  ENSCLAT00000001022.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Myotonic_dystrophy_kinase_coil UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Dmpk ENTREZGENE
PANTHER MYOTONIC DYSTROPHY S/T KINASE-RELATED UniProtKB/TrEMBL
  NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE UniProtKB/TrEMBL
Pfam DMPK_coil UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2UJA7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UNJ0_CHILA UniProtKB/TrEMBL
  A0A8C2YIF3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-06 Dmpk  DM1 protein kinase    dystrophia myotonica protein kinase  Symbol and/or name change 5135510 APPROVED
2016-08-16 Dmpk  dystrophia myotonica protein kinase    dystrophia myotonica-protein kinase  Symbol and/or name change 5135510 APPROVED