Trhde (thyrotropin releasing hormone degrading enzyme) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Trhde (thyrotropin releasing hormone degrading enzyme) Chinchilla lanigera
Analyze
Symbol: Trhde
Name: thyrotropin releasing hormone degrading enzyme
RGD ID: 8735671
Description: ASSOCIATED WITH long QT syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thyrotropin-releasing hormone degrading enzyme; thyrotropin-releasing hormone-degrading ectoenzyme
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540512,229,448 - 12,623,675 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540512,229,448 - 12,624,753 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trhde
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540512,229,448 - 12,623,675 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540512,229,448 - 12,624,753 (+)NCBIChiLan1.0ChiLan1.0
TRHDE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381272,087,266 - 72,670,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1272,087,266 - 72,670,758 (+)EnsemblGRCh38hg38GRCh38
GRCh371272,666,150 - 73,064,538 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361270,952,730 - 71,345,689 (+)NCBINCBI36Build 36hg18NCBI36
Build 341270,952,729 - 71,345,688NCBI
Celera1272,329,850 - 72,723,987 (+)NCBICelera
Cytogenetic Map12q21.1NCBI
HuRef1269,714,852 - 70,107,634 (+)NCBIHuRef
CHM1_11272,632,089 - 73,024,946 (+)NCBICHM1_1
T2T-CHM13v2.01272,063,195 - 72,646,521 (+)NCBIT2T-CHM13v2.0
Trhde
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910114,234,725 - 114,638,207 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10114,234,726 - 114,638,212 (-)EnsemblGRCm39 Ensembl
GRCm3810114,398,820 - 114,802,302 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10114,398,821 - 114,802,307 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl10114,398,823 - 114,802,307 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710113,835,877 - 114,238,426 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610113,803,133 - 114,205,474 (-)NCBIMGSCv36mm8
Celera10116,334,960 - 116,737,119 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1061.59NCBI
Trhde
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8751,829,473 - 52,236,843 (-)NCBIGRCr8
mRatBN7.2749,943,271 - 50,350,613 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl749,945,766 - 50,367,371 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx751,852,771 - 52,257,524 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0754,055,893 - 54,460,654 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0753,833,748 - 54,238,531 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0757,253,023 - 57,679,795 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl757,253,023 - 57,679,795 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0757,265,684 - 57,693,174 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4753,591,770 - 54,021,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1753,612,156 - 54,024,183 (-)NCBI
Celera746,740,631 - 47,161,218 (-)NCBICelera
Cytogenetic Map7q22NCBI
TRHDE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21080,300,714 - 80,696,949 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11280,297,114 - 80,693,349 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01269,795,208 - 70,191,298 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11272,652,776 - 73,047,182 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1272,652,958 - 73,073,418 (+)Ensemblpanpan1.1panPan2
TRHDE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11013,744,907 - 14,118,023 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1013,744,591 - 14,115,437 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1013,685,019 - 14,055,891 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01013,883,046 - 14,254,797 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1013,883,046 - 14,249,827 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11013,743,941 - 14,115,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01013,995,000 - 14,365,815 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01014,116,319 - 14,488,005 (+)NCBIUU_Cfam_GSD_1.0
Trhde
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494544,067,297 - 44,437,562 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365681,290,774 - 1,662,542 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365681,290,758 - 1,660,520 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRHDE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl536,274,165 - 36,658,701 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1536,266,883 - 36,663,208 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2539,289,649 - 39,520,695 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRHDE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11167,912,122 - 68,313,509 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1167,912,138 - 68,315,962 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037177,295,134 - 177,727,707 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trhde
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475025,007,540 - 25,419,433 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475025,000,907 - 25,419,628 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000008467   ⟹   ENSCLAP00000008340
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540512,229,448 - 12,623,675 (+)Ensembl
RefSeq Acc Id: XM_005374325   ⟹   XP_005374382
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540512,229,448 - 12,624,753 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374382 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008340
  ENSCLAP00000008340.1
RefSeq Acc Id: XP_005374382   ⟸   XM_005374325
- UniProtKB: A0A8C2YLX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008340   ⟸   ENSCLAT00000008467

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005841 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008467 ENTREZGENE
  ENSCLAT00000008467.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.390.10 UniProtKB/TrEMBL
  1.25.50.20 UniProtKB/TrEMBL
  2.60.40.1730 UniProtKB/TrEMBL
  2.60.40.1910 UniProtKB/TrEMBL
InterPro Aminopeptidase_N-like_N UniProtKB/TrEMBL
  Aminopeptidase_N-like_N_sf UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/TrEMBL
  Peptidase_M4/M1_CTD_sf UniProtKB/TrEMBL
NCBI Gene Trhde ENTREZGENE
PANTHER PROTEASE M1 ZINC METALLOPROTEASE UniProtKB/TrEMBL
  PTHR11533:SF40 UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_N UniProtKB/TrEMBL
PRINTS ALADIPTASE UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF63737 UniProtKB/TrEMBL
UniProt A0A8C2YLX7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Trhde  thyrotropin releasing hormone degrading enzyme    thyrotropin-releasing hormone degrading enzyme  Symbol and/or name change 5135510 APPROVED